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Items: 1 to 50 of 553

1.

Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation.

Momper JD, Yang J, Gockenbach M, Vaida F, Nigam SK.

Clin J Am Soc Nephrol. 2019 Apr 5;14(4):540-548. doi: 10.2215/CJN.10350818. Epub 2019 Mar 18.

PMID:
30885911
2.

Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling.

Nigam SK, Bush KT.

Nat Rev Nephrol. 2019 May;15(5):301-316. doi: 10.1038/s41581-019-0111-1. Review.

PMID:
30728454
3.

Polyarteritis nodosa presenting atypically as appendicitis and pyelonephritis in a single patient.

Corbitt M, Kurtkoti J, Rashid M, Nigam S.

BMJ Case Rep. 2019 Feb 1;12(2). pii: e228072. doi: 10.1136/bcr-2018-228072.

PMID:
30709887
4.

Inverse Association Between HDL (High-Density Lipoprotein) Cholesterol and Stroke Risk Among Patients With Type 2 Diabetes Mellitus.

Shen Y, Shi L, Nauman E, Katzmarzyk PT, Price-Haywood EG, Bazzano AN, Nigam S, Hu G.

Stroke. 2019 Feb;50(2):291-297. doi: 10.1161/STROKEAHA.118.023682.

PMID:
30626289
5.

Epigenetic Silencing of miRNA-338-5p and miRNA-421 Drives SPINK1-Positive Prostate Cancer.

Bhatia V, Yadav A, Tiwari R, Nigam S, Goel S, Carskadon S, Gupta N, Goel A, Palanisamy N, Ateeq B.

Clin Cancer Res. 2019 May 1;25(9):2755-2768. doi: 10.1158/1078-0432.CCR-18-3230. Epub 2018 Dec 26.

PMID:
30587549
6.

Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.

Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P.

Am J Med Genet A. 2019 Jan;179(1):71-77. doi: 10.1002/ajmg.a.40481. Epub 2018 Nov 13.

PMID:
30422383
7.

Neurotheranostics as personalized medicines.

Kevadiya BD, Ottemann BM, Thomas MB, Mukadam I, Nigam S, McMillan J, Gorantla S, Bronich TK, Edagwa B, Gendelman HE.

Adv Drug Deliv Rev. 2018 Oct 26. pii: S0169-409X(18)30261-8. doi: 10.1016/j.addr.2018.10.011. [Epub ahead of print] Review.

8.

Race and sex differences in rates of diabetic complications.

Shen Y, Shi L, Nauman E, Katzmarzyk PT, Price-Haywood EG, Yin P, Bazzano AN, Nigam S, Hu G.

J Diabetes. 2019 Jun;11(6):449-456. doi: 10.1111/1753-0407.12869. Epub 2018 Nov 13.

PMID:
30315628
9.

Single atom alloy catalyst for SO3 decomposition: enhancement of platinum catalyst's performance by Ag atom embedding.

Nigam S, Majumder C.

Nanoscale. 2018 Nov 15;10(44):20599-20610. doi: 10.1039/c8nr05179h.

PMID:
30277248
10.

Desulfination by 2'-hydroxybiphenyl-2-sulfinate desulfinase proceeds via electrophilic aromatic substitution by the cysteine-27 proton.

Geronimo I, Nigam SR, Payne CM.

Chem Sci. 2017 Jul 1;8(7):5078-5086. doi: 10.1039/c7sc00496f. Epub 2017 May 17.

11.

Sporadic Burkitt's lymphoma masquerading as an intussuscepted Meckel's diverticulum in a 9-year-old child.

Ng JY, Thompson RJ, Lam A, Nigam S.

BMJ Case Rep. 2018 Jul 24;2018. pii: bcr-2018-224333. doi: 10.1136/bcr-2018-224333.

PMID:
30042102
12.

Temporal transcriptomic analysis of metabolic genes in maternal organs and placenta during murine pregnancy.

Paquette A, Baloni P, Holloman AB, Nigam S, Bammler T, Mao Q, Price ND.

Biol Reprod. 2018 Dec 1;99(6):1255-1265. doi: 10.1093/biolre/ioy148.

PMID:
29939228
13.

Synthesis, crystal structure, and cytotoxicity studies of titanacalix[4 and 8]arene complexes.

Miller-Shakesby DM, Nigam S, Hughes DL, Lopez-Estelles E, Elsegood MRJ, Cawthorne CJ, Archibald SJ, Redshaw C.

Dalton Trans. 2018 Jul 10;47(27):8992-8999. doi: 10.1039/c8dt01992d.

PMID:
29922776
14.

The systems biology of uric acid transporters: the role of remote sensing and signaling.

Nigam SK, Bhatnagar V.

Curr Opin Nephrol Hypertens. 2018 Jul;27(4):305-313. doi: 10.1097/MNH.0000000000000427. Review.

15.

Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication.

Momper JD, Nigam SK.

Expert Opin Drug Metab Toxicol. 2018 Jun;14(6):561-570. doi: 10.1080/17425255.2018.1473376. Epub 2018 Jun 4. Review.

16.

Overexpression of SNX3 Decreases Amyloid-β Peptide Production by Reducing Internalization of Amyloid Precursor Protein.

Xu S, Nigam SM, Brodin L.

Neurodegener Dis. 2018;18(1):26-37. doi: 10.1159/000486199. Epub 2018 Feb 7.

17.

Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin.

Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolic I, Vallon V.

Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F386-F394. doi: 10.1152/ajprenal.00503.2017. Epub 2018 Feb 7.

PMID:
29412698
18.

Doxorubicin-loaded dendritic-Fe3O4 supramolecular nanoparticles for magnetic drug targeting and tumor regression in spheroid murine melanoma model.

Nigam S, Bahadur D.

Nanomedicine. 2018 Apr;14(3):759-768. doi: 10.1016/j.nano.2018.01.005. Epub 2018 Jan 12.

PMID:
29339187
19.

The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease.

Nigam SK.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:663-687. doi: 10.1146/annurev-pharmtox-010617-052713.

20.

Bimetallic Ag-Pt Sub-nanometer Supported Clusters as Highly Efficient and Robust Oxidation Catalysts.

Negreiros FR, Halder A, Yin C, Singh A, Barcaro G, Sementa L, Tyo EC, Pellin MJ, Bartling S, Meiwes-Broer KH, Seifert S, Sen P, Nigam S, Majumder C, Fukui N, Yasumatsu H, Vajda S, Fortunelli A.

Angew Chem Int Ed Engl. 2018 Jan 26;57(5):1209-1213. doi: 10.1002/anie.201709784. Epub 2017 Dec 29.

PMID:
29239093
21.
22.

Anti-glomerular basement membrane glomerulonephritis following nintedanib for idiopathic pulmonary fibrosis: a case report.

Ismail I, Nigam S, Parnham A, Srinivasa V.

J Med Case Rep. 2017 Aug 6;11(1):214. doi: 10.1186/s13256-017-1384-2.

23.

The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut-liver-kidney axis.

Bush KT, Wu W, Lun C, Nigam SK.

J Biol Chem. 2017 Sep 22;292(38):15789-15803. doi: 10.1074/jbc.M117.796516. Epub 2017 Aug 1.

24.

Storage of nitroglycerin (NTG) admixed with HBOC-201 for 30 days in polyolefin plastic bags: a pilot study.

Nigam S, McCarron R, Arnaud F.

Drug Deliv Transl Res. 2017 Oct;7(5):674-682. doi: 10.1007/s13346-017-0411-6.

PMID:
28744782
25.

ORR viability of alumina-supported platinum nanocluster: exploring oxidation behaviour by DFT.

Nigam S, Majumder C.

Phys Chem Chem Phys. 2017 Jul 26;19(29):19308-19315. doi: 10.1039/c7cp04029f.

PMID:
28703240
26.

Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes.

Wu W, Bush KT, Nigam SK.

Sci Rep. 2017 Jul 10;7(1):4939. doi: 10.1038/s41598-017-04949-2.

27.

Molecular Mapping of Oil Content and Fatty Acids Using Dense Genetic Maps in Groundnut (Arachis hypogaea L.).

Shasidhar Y, Vishwakarma MK, Pandey MK, Janila P, Variath MT, Manohar SS, Nigam SN, Guo B, Varshney RK.

Front Plant Sci. 2017 May 22;8:794. doi: 10.3389/fpls.2017.00794. eCollection 2017.

28.

Dendrimer-conjugated iron oxide nanoparticles as stimuli-responsive drug carriers for thermally-activated chemotherapy of cancer.

Nigam S, Bahadur D.

Colloids Surf B Biointerfaces. 2017 Jul 1;155:182-192. doi: 10.1016/j.colsurfb.2017.04.025. Epub 2017 Apr 13.

PMID:
28431327
29.

Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP.

Nigam SM, Xu S, Kritikou JS, Marosi K, Brodin L, Mattson MP.

J Neurochem. 2017 Jul;142(2):286-296. doi: 10.1111/jnc.14034. Epub 2017 May 18.

30.

Ag/AgO Nanoparticles Grown via Time Dependent Double Mechanism in a 2D Layered Ni-PCP and Their Antibacterial Efficacy.

Agarwal RA, Gupta NK, Singh R, Nigam S, Ateeq B.

Sci Rep. 2017 Mar 21;7:44852. doi: 10.1038/srep44852.

31.

Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic and Ca2+-Handling Deficits in Alzheimer's Disease Models.

Eitan E, Hutchison ER, Marosi K, Comotto J, Mustapic M, Nigam SM, Suire C, Maharana C, Jicha GA, Liu D, Machairaki V, Witwer KW, Kapogiannis D, Mattson MP.

NPJ Aging Mech Dis. 2016;2. pii: 16019. Epub 2016 Sep 22.

32.

Vehicular traffic noise prediction using soft computing approach.

Singh D, Nigam SP, Agrawal VP, Kumar M.

J Environ Manage. 2016 Dec 1;183:59-66. doi: 10.1016/j.jenvman.2016.08.053. Epub 2016 Aug 27.

PMID:
27576153
33.

Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach.

Liu HC, Goldenberg A, Chen Y, Lun C, Wu W, Bush KT, Balac N, Rodriguez P, Abagyan R, Nigam SK.

J Pharmacol Exp Ther. 2016 Oct;359(1):215-29. doi: 10.1124/jpet.116.232660. Epub 2016 Aug 3.

34.

Population-Level Prediction of Type 2 Diabetes From Claims Data and Analysis of Risk Factors.

Razavian N, Blecker S, Schmidt AM, Smith-McLallen A, Nigam S, Sontag D.

Big Data. 2015 Dec;3(4):277-87. doi: 10.1089/big.2015.0020.

PMID:
27441408
35.

An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.

Liu HC, Jamshidi N, Chen Y, Eraly SA, Cho SY, Bhatnagar V, Wu W, Bush KT, Abagyan R, Palsson BO, Nigam SK.

J Biol Chem. 2016 Sep 9;291(37):19474-86. doi: 10.1074/jbc.M116.745216. Epub 2016 Jul 20.

36.

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.

Bhatnagar V, Richard EL, Wu W, Nievergelt CM, Lipkowitz MS, Jeff J, Maihofer AX, Nigam SK.

Clin Kidney J. 2016 Jun;9(3):444-53. doi: 10.1093/ckj/sfw010. Epub 2016 Apr 5.

37.

Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells.

Nigam S, Burke BP, Davies LH, Domarkas J, Wallis JF, Waddell PG, Waby JS, Benoit DM, Seymour AM, Cawthorne C, Higham LJ, Archibald SJ.

Chem Commun (Camb). 2016 May 24;52(44):7114-7. doi: 10.1039/c5cc08325g.

PMID:
27166476
38.

High-Degree Neurons Feed Cortical Computations.

Timme NM, Ito S, Myroshnychenko M, Nigam S, Shimono M, Yeh FC, Hottowy P, Litke AM, Beggs JM.

PLoS Comput Biol. 2016 May 9;12(5):e1004858. doi: 10.1371/journal.pcbi.1004858. eCollection 2016 May.

39.

Alveolar proteinosis associated with aluminium dust inhalation.

Chew R, Nigam S, Sivakumaran P.

Occup Med (Lond). 2016 Aug;66(6):492-4. doi: 10.1093/occmed/kqw049. Epub 2016 Apr 19.

PMID:
27099254
40.

Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2.

He X, Garza D, Nigam SK, Chang G.

PLoS One. 2016 Apr 5;11(4):e0152969. doi: 10.1371/journal.pone.0152969. eCollection 2016.

41.

Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers.

Martovetsky G, Bush KT, Nigam SK.

Drug Metab Dispos. 2016 Jul;44(7):1050-60. doi: 10.1124/dmd.115.068254. Epub 2016 Apr 4.

42.

Endogenous APP accumulates in synapses after BACE1 inhibition.

Nigam SM, Xu S, Ackermann F, Gregory JA, Lundkvist J, Lendahl U, Brodin L.

Neurosci Res. 2016 Aug;109:9-15. doi: 10.1016/j.neures.2016.02.002. Epub 2016 Feb 22.

PMID:
26907521
43.

Self-sustainable Chlorella pyrenoidosa strain NCIM 2738 based photobioreactor for removal of Direct Red-31 dye along with other industrial pollutants to improve the water-quality.

Sinha S, Singh R, Chaurasia AK, Nigam S.

J Hazard Mater. 2016 Apr 5;306:386-394. doi: 10.1016/j.jhazmat.2015.12.011. Epub 2015 Dec 10.

PMID:
26826964
44.

Rich-Club Organization in Effective Connectivity among Cortical Neurons.

Nigam S, Shimono M, Ito S, Yeh FC, Timme N, Myroshnychenko M, Lapish CC, Tosi Z, Hottowy P, Smith WC, Masmanidis SC, Litke AM, Sporns O, Beggs JM.

J Neurosci. 2016 Jan 20;36(3):670-84. doi: 10.1523/JNEUROSCI.2177-15.2016.

45.

Platinum-Mediated Activation of Coordinated Organonitriles by Telluroethers in Tetrahydrofuran: Isolation, Structural Characterization, and Density Functional Theory Analysis of Intermediate Complexes.

Kolay S, Wadawale A, Nigam S, Kumar M, Majumder C, Das D, Jain VK.

Inorg Chem. 2015 Dec 21;54(24):11741-50. doi: 10.1021/acs.inorgchem.5b02024. Epub 2015 Dec 15.

PMID:
26669361
46.

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells.

Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K.

Elife. 2015 Nov 10;4. pii: e08413. doi: 10.7554/eLife.08413.

47.

Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs.

Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH Jr, Wu W, Nigam SK.

PLoS One. 2015 Nov 4;10(11):e0140569. doi: 10.1371/journal.pone.0140569. eCollection 2015.

48.

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.

Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V.

Clin J Am Soc Nephrol. 2015 Nov 6;10(11):2039-49. doi: 10.2215/CJN.02440314. Epub 2015 Oct 21.

49.

Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors.

Wu W, Bush KT, Liu HC, Zhu C, Abagyan R, Nigam SK.

Drug Metab Dispos. 2015 Dec;43(12):1855-63. doi: 10.1124/dmd.115.065250. Epub 2015 Sep 10.

50.

Targets in anticancer research--A review.

Jayashree BS, Nigam S, Pai A, Patel HK, Reddy ND, Kumar N, Rao CM.

Indian J Exp Biol. 2015 Aug;53(8):489-507. Review.

PMID:
26349312

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