Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 165

1.

The Bilayer Collective Properties Govern the Interaction of an HIV-1 Antibody with the Viral Membrane.

Carravilla P, Darré L, Oar-Arteta IR, Vesga AG, Rujas E, de Las Heras-Martínez G, Domene C, Nieva JL, Requejo-Isidro J.

Biophys J. 2019 Nov 14. pii: S0006-3495(19)30910-5. doi: 10.1016/j.bpj.2019.11.005. [Epub ahead of print]

PMID:
31787208
2.

Mandatory Research Biopsy Requirements Delay Initiation of Clinical Trials.

Cheng JH, Tiulim JW, Zhou S, El-Khoueiry A, Nieva J.

Front Oncol. 2019 Oct 18;9:968. doi: 10.3389/fonc.2019.00968. eCollection 2019.

3.

A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study.

Schenk EL, Mandrekar SJ, Dy GK, Aubry MC, Tan AD, Dakhil SR, Sachs BA, Nieva JJ, Bertino E, Lee Hann C, Schild SE, Wadsworth TW, Adjei AA, Molina JR.

J Thorac Oncol. 2019 Oct 9. pii: S1556-0864(19)33411-2. doi: 10.1016/j.jtho.2019.09.083. [Epub ahead of print]

PMID:
31605793
4.

Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer.

Shishido SN, Carlsson A, Nieva J, Bethel K, Hicks JB, Bazhenova L, Kuhn P.

J Transl Med. 2019 Aug 28;17(1):294. doi: 10.1186/s12967-019-2035-8.

5.

Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer.

Horn L, Whisenant JG, Wakelee H, Reckamp KL, Qiao H, Leal TA, Du L, Hernandez J, Huang V, Blumenschein GR, Waqar SN, Patel SP, Nieva J, Oxnard GR, Sanborn RE, Shaffer T, Garg K, Holzhausen A, Harrow K, Liang C, Lim LP, Li M, Lovly CM.

J Thorac Oncol. 2019 Nov;14(11):1901-1911. doi: 10.1016/j.jtho.2019.08.003. Epub 2019 Aug 22.

PMID:
31446141
6.

Patient reported outcomes can improve performance status assessment: a pilot study.

Broderick JE, May M, Schwartz JE, Li M, Mejia A, Nocera L, Kolatkar A, Ueno NT, Yennu S, Lee JSH, Hanlon SE, Cozzens Philips FA, Shahabi C, Kuhn P, Nieva J.

J Patient Rep Outcomes. 2019 Jul 16;3(1):41. doi: 10.1186/s41687-019-0136-z.

7.

Trimodality vs Chemoradiation and Salvage Resection in cN2 Stage IIIA Non-Small Cell Lung Cancer.

Ye JC, Ding L, Atay SM, Nieva JJ, McFadden PM, Chang E, Kim AW.

Semin Thorac Cardiovasc Surg. 2019 Jun 17. pii: S1043-0679(19)30172-8. doi: 10.1053/j.semtcvs.2019.06.002. [Epub ahead of print]

PMID:
31220530
8.

Detection of NRG1 Gene Fusions in Solid Tumors.

Jonna S, Feldman RA, Swensen J, Gatalica Z, Korn WM, Borghaei H, Ma PC, Nieva JJ, Spira AI, Vanderwalde AM, Wozniak AJ, Kim ES, Liu SV.

Clin Cancer Res. 2019 Aug 15;25(16):4966-4972. doi: 10.1158/1078-0432.CCR-19-0160. Epub 2019 Apr 15.

PMID:
30988082
9.

Intracellular delivery of mRNA to human primary T cells with microfluidic vortex shedding.

Jarrell JA, Twite AA, Lau KHWJ, Kashani MN, Lievano AA, Acevedo J, Priest C, Nieva J, Gottlieb D, Pawell RS.

Sci Rep. 2019 Mar 1;9(1):3214. doi: 10.1038/s41598-019-40147-y.

10.

Tuberculosis following PD-1 blockade for cancer immunotherapy.

Barber DL, Sakai S, Kudchadkar RR, Fling SP, Day TA, Vergara JA, Ashkin D, Cheng JH, Lundgren LM, Raabe VN, Kraft CS, Nieva JJ, Cheever MA, Nghiem PT, Sharon E.

Sci Transl Med. 2019 Jan 16;11(475). pii: eaat2702. doi: 10.1126/scitranslmed.aat2702.

PMID:
30651320
11.

Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions.

Carravilla P, Chojnacki J, Rujas E, Insausti S, Largo E, Waithe D, Apellaniz B, Sicard T, Julien JP, Eggeling C, Nieva JL.

Nat Commun. 2019 Jan 8;10(1):78. doi: 10.1038/s41467-018-07962-9.

12.

Radiomics in Pulmonary Lesion Imaging.

Hassani C, Varghese BA, Nieva J, Duddalwar V.

AJR Am J Roentgenol. 2019 Mar;212(3):497-504. doi: 10.2214/AJR.18.20623. Epub 2019 Jan 8.

PMID:
30620678
13.

A new anion exchange purification method for Cu stable isotopes in blood samples.

Yang SC, Welter L, Kolatkar A, Nieva J, Waitman KR, Huang KF, Liao WH, Takano S, Berelson WM, West AJ, Kuhn P, John SG.

Anal Bioanal Chem. 2019 Jan;411(3):765-776. doi: 10.1007/s00216-018-1498-4. Epub 2018 Nov 22.

PMID:
30467768
14.

Identification of Novel Gymnodimines and Spirolides from the Marine Dinoflagellate Alexandrium ostenfeldii.

Zurhelle C, Nieva J, Tillmann U, Harder T, Krock B, Tebben J.

Mar Drugs. 2018 Nov 14;16(11). pii: E446. doi: 10.3390/md16110446.

15.

Development of metastatic brain disease involves progression through lung metastases in EGFR mutated non-small cell lung cancer.

In G, Mason J, Lin S, Newton PK, Kuhn P, Nieva J.

Converg Sci Phys Oncol. 2017 Sep;3(3). pii: 034001. Epub 2017 Jul 13.

16.

Molecular Characterization of the Viroporin Function of Foot-and-Mouth Disease Virus Nonstructural Protein 2B.

Gladue DP, Largo E, de la Arada I, Aguilella VM, Alcaraz A, Arrondo JLR, Holinka LG, Brocchi E, Ramirez-Medina E, Vuono EA, Berggren KA, Carrillo C, Nieva JL, Borca MV.

J Virol. 2018 Nov 12;92(23). pii: e01360-18. doi: 10.1128/JVI.01360-18. Print 2018 Dec 1.

17.

Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum.

Gladue DP, Largo E, Holinka LG, Ramirez-Medina E, Vuono EA, Berggren KA, Risatti GR, Nieva JL, Borca MV.

Viruses. 2018 Aug 28;10(9). pii: E460. doi: 10.3390/v10090460.

18.

Low-dimensional dynamical characterization of human performance of cancer patients using motion data.

Hasnain Z, Li M, Dorff T, Quinn D, Ueno NT, Yennu S, Kolatkar A, Shahabi C, Nocera L, Nieva J, Kuhn P, Newton PK.

Clin Biomech (Bristol, Avon). 2018 Jul;56:61-69. doi: 10.1016/j.clinbiomech.2018.05.007. Epub 2018 May 18.

PMID:
29803824
19.

When it comes to genomic analysis of tumours, don't buy in bulk.

Nieva J, Hicks J.

Br J Cancer. 2018 May;118(10):1281-1282. doi: 10.1038/s41416-018-0096-8. Epub 2018 May 10.

20.

Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds.

Oakes V, Torralba J, Rujas E, Nieva JL, Domene C, Apellaniz B.

Biochim Biophys Acta Biomembr. 2018 Jun;1860(6):1259-1271. doi: 10.1016/j.bbamem.2018.02.019. Epub 2018 Feb 23.

21.

Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions.

Rujas E, Leaman DP, Insausti S, Ortigosa-Pascual L, Zhang L, Zwick MB, Nieva JL.

J Virol. 2018 Mar 28;92(8). pii: e02249-17. doi: 10.1128/JVI.02249-17. Print 2018 Apr 15.

22.

Mutation-induced changes of transmembrane pore size revealed by combined ion-channel conductance and single vesicle permeabilization analyses.

Largo E, Gladue DP, Torralba J, Aguilella VM, Alcaraz A, Borca MV, Nieva JL.

Biochim Biophys Acta Biomembr. 2018 May;1860(5):1015-1021. doi: 10.1016/j.bbamem.2018.01.012. Epub 2018 Jan 6.

23.

Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay.

Rodríguez-Lee M, Kolatkar A, McCormick M, Dago AD, Kendall J, Carlsson NA, Bethel K, Greenspan EJ, Hwang SE, Waitman KR, Nieva JJ, Hicks J, Kuhn P.

Arch Pathol Lab Med. 2018 Feb;142(2):198-207. doi: 10.5858/arpa.2016-0483-OA. Epub 2017 Nov 16.

PMID:
29144792
24.

Structure-Related Roles for the Conservation of the HIV-1 Fusion Peptide Sequence Revealed by Nuclear Magnetic Resonance.

Serrano S, Huarte N, Rujas E, Andreu D, Nieva JL, Jiménez MA.

Biochemistry. 2017 Oct 17;56(41):5503-5511. doi: 10.1021/acs.biochem.7b00745. Epub 2017 Sep 29.

PMID:
28930470
25.

Biophysical technologies for understanding circulating tumor cell biology and metastasis.

Su DW, Nieva J.

Transl Lung Cancer Res. 2017 Aug;6(4):473-485. doi: 10.21037/tlcr.2017.05.08. Review.

26.

Effects of HIV-1 gp41-Derived Virucidal Peptides on Virus-like Lipid Membranes.

Carravilla P, Cruz A, Martin-Ugarte I, Oar-Arteta IR, Torralba J, Apellaniz B, Pérez-Gil J, Requejo-Isidro J, Huarte N, Nieva JL.

Biophys J. 2017 Sep 19;113(6):1301-1310. doi: 10.1016/j.bpj.2017.06.061. Epub 2017 Aug 7.

27.

Cellular Expression of PD-L1 in the Peripheral Blood of Lung Cancer Patients is Associated with Worse Survival.

Boffa DJ, Graf RP, Salazar MC, Hoag J, Lu D, Krupa R, Louw J, Dugan L, Wang Y, Landers M, Suraneni M, Greene SB, Magaña M, Makani S, Bazhenova L, Dittamore RV, Nieva J.

Cancer Epidemiol Biomarkers Prev. 2017 Jul;26(7):1139-1145. doi: 10.1158/1055-9965.EPI-17-0120. Epub 2017 Apr 26.

28.

Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane.

Rujas E, Insausti S, García-Porras M, Sánchez-Eugenia R, Tsumoto K, Nieva JL, Caaveiro JM.

J Mol Biol. 2017 Apr 21;429(8):1213-1226. doi: 10.1016/j.jmb.2017.03.008. Epub 2017 Mar 11.

29.

Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody.

Rujas E, Caaveiro JM, Insausti S, García-Porras M, Tsumoto K, Nieva JL.

J Biol Chem. 2017 Mar 31;292(13):5571-5583. doi: 10.1074/jbc.M117.775429. Epub 2017 Feb 17.

30.

Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.

Rujas E, Caaveiro JM, Partida-Hanon A, Gulzar N, Morante K, Apellániz B, García-Porras M, Bruix M, Tsumoto K, Scott JK, Jiménez MÁ, Nieva JL.

Sci Rep. 2016 Dec 1;6:38177. doi: 10.1038/srep38177.

31.

Alteration of a Second Putative Fusion Peptide of Structural Glycoprotein E2 of Classical Swine Fever Virus Alters Virus Replication and Virulence in Swine.

Holinka LG, Largo E, Gladue DP, O'Donnell V, Risatti GR, Nieva JL, Borca MV.

J Virol. 2016 Oct 28;90(22):10299-10308. doi: 10.1128/JVI.01530-16. Print 2016 Nov 15.

32.

A Randomized Phase II Study of Linsitinib (OSI-906) Versus Topotecan in Patients With Relapsed Small-Cell Lung Cancer.

Chiappori AA, Otterson GA, Dowlati A, Traynor AM, Horn L, Owonikoko TK, Ross HJ, Hann CL, Abu Hejleh T, Nieva J, Zhao X, Schell M, Sullivan DM.

Oncologist. 2016 Oct;21(10):1163-1164. Epub 2016 Sep 30.

33.

Functional organization of the HIV lipid envelope.

Huarte N, Carravilla P, Cruz A, Lorizate M, Nieto-Garai JA, Kräusslich HG, Pérez-Gil J, Requejo-Isidro J, Nieva JL.

Sci Rep. 2016 Sep 28;6:34190. doi: 10.1038/srep34190.

34.

Reply to "The Broadly Neutralizing, Anti-HIV Antibody 4E10: an Open and Shut Case?".

Rujas E, Gulzar N, Morante K, Tsumoto K, Scott JK, Nieva JL, Caaveiro JM.

J Virol. 2016 Feb 26;90(6):3276-7. doi: 10.1128/JVI.02970-15. Print 2016 Mar. No abstract available.

35.

Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites.

Newton PK, Mason J, Venkatappa N, Jochelson MS, Hurt B, Nieva J, Comen E, Norton L, Kuhn P.

NPJ Breast Cancer. 2015 Oct 21;1:15018. doi: 10.1038/npjbcancer.2015.18. eCollection 2015.

36.

Ion channel activity of the CSFV p7 viroporin in surrogates of the ER lipid bilayer.

Largo E, Verdiá-Báguena C, Aguilella VM, Nieva JL, Alcaraz A.

Biochim Biophys Acta. 2016 Jan;1858(1):30-7. doi: 10.1016/j.bbamem.2015.10.007. Epub 2015 Oct 14.

37.

Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10.

Rujas E, Gulzar N, Morante K, Tsumoto K, Scott JK, Nieva JL, Caaveiro JM.

J Virol. 2015 Dec;89(23):11975-89. doi: 10.1128/JVI.01793-15. Epub 2015 Sep 16.

38.

The Use of Liposomes to Shape Epitope Structure and Modulate Immunogenic Responses of Peptide Vaccines Against HIV MPER.

Apellániz B, Nieva JL.

Adv Protein Chem Struct Biol. 2015;99:15-54. doi: 10.1016/bs.apcsb.2015.03.002. Epub 2015 Apr 18. Review.

PMID:
26067815
39.

Oncolytic viruses: perspectives on clinical development.

Burke J, Nieva J, Borad MJ, Breitbach CJ.

Curr Opin Virol. 2015 Aug;13:55-60. doi: 10.1016/j.coviro.2015.03.020. Epub 2015 May 16. Review.

PMID:
25989094
40.

The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region.

Apellániz B, Rujas E, Serrano S, Morante K, Tsumoto K, Caaveiro JM, Jiménez MÁ, Nieva JL.

J Biol Chem. 2015 May 22;290(21):12999-3015. doi: 10.1074/jbc.M115.644351. Epub 2015 Mar 18.

41.

Two-photon Laurdan studies of the ternary lipid mixture DOPC:SM:cholesterol reveal a single liquid phase at sphingomyelin:cholesterol ratios lower than 1.

Carravilla P, Nieva JL, Goñi FM, Requejo-Isidro J, Huarte N.

Langmuir. 2015 Mar 10;31(9):2808-17. doi: 10.1021/la504251u. Epub 2015 Feb 25.

PMID:
25658036
42.

Fusion-competent state induced by a C-terminal HIV-1 fusion peptide in cholesterol-rich membranes.

Apellániz B, Nieva JL.

Biochim Biophys Acta. 2015 Apr;1848(4):1014-22. doi: 10.1016/j.bbamem.2015.01.011. Epub 2015 Jan 21.

43.

A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma.

Gilbert J, Schell MJ, Zhao X, Murphy B, Tanvetyanon T, Leon ME, Neil Hayes D, Haigentz M Jr, Saba N, Nieva J, Bishop J, Sidransky D, Ravi R, Bedi A, Chung CH.

Oral Oncol. 2015 Apr;51(4):376-82. doi: 10.1016/j.oraloncology.2014.12.011. Epub 2015 Jan 13.

44.

Entropy, complexity, and Markov diagrams for random walk cancer models.

Newton PK, Mason J, Hurt B, Bethel K, Bazhenova L, Nieva J, Kuhn P.

Sci Rep. 2014 Dec 19;4:7558. doi: 10.1038/srep07558.

45.

Cholesterol-dependent membrane fusion induced by the gp41 membrane-proximal external region-transmembrane domain connection suggests a mechanism for broad HIV-1 neutralization.

Apellániz B, Rujas E, Carravilla P, Requejo-Isidro J, Huarte N, Domene C, Nieva JL.

J Virol. 2014 Nov;88(22):13367-77. doi: 10.1128/JVI.02151-14. Epub 2014 Sep 10.

46.

Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer.

Carlsson A, Nair VS, Luttgen MS, Keu KV, Horng G, Vasanawala M, Kolatkar A, Jamali M, Iagaru AH, Kuschner W, Loo BW Jr, Shrager JB, Bethel K, Hoh CK, Bazhenova L, Nieva J, Kuhn P, Gambhir SS.

J Thorac Oncol. 2014 Aug;9(8):1111-9. doi: 10.1097/JTO.0000000000000235.

47.

Effect of specific amino acid substitutions in the putative fusion peptide of structural glycoprotein E2 on Classical Swine Fever Virus replication.

Fernández-Sainz IJ, Largo E, Gladue DP, Fletcher P, O'Donnell V, Holinka LG, Carey LB, Lu X, Nieva JL, Borca MV.

Virology. 2014 May;456-457:121-30. doi: 10.1016/j.virol.2014.03.005. Epub 2014 Apr 4.

48.

Adrenal metastases in lung cancer: clinical implications of a mathematical model.

Bazhenova L, Newton P, Mason J, Bethel K, Nieva J, Kuhn P.

J Thorac Oncol. 2014 Apr;9(4):442-6. doi: 10.1097/JTO.0000000000000133. Review.

49.

The three lives of viral fusion peptides.

Apellániz B, Huarte N, Largo E, Nieva JL.

Chem Phys Lipids. 2014 Jul;181:40-55. doi: 10.1016/j.chemphyslip.2014.03.003. Epub 2014 Apr 2. Review.

50.

Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: implications for antibody recognition mechanism and immunogen design.

Serrano S, Araujo A, Apellániz B, Bryson S, Carravilla P, de la Arada I, Huarte N, Rujas E, Pai EF, Arrondo JL, Domene C, Jiménez MA, Nieva JL.

J Biol Chem. 2014 Mar 7;289(10):6565-80. doi: 10.1074/jbc.M113.527747. Epub 2014 Jan 15.

Supplemental Content

Support Center