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Items: 40


Constitutive Inactivation of the PRRT2 Gene Alters Short-Term Synaptic Plasticity and Promotes Network Hyperexcitability in Hippocampal Neurons.

Valente P, Romei A, Fadda M, Sterlini B, Lonardoni D, Forte N, Fruscione F, Castroflorio E, Michetti C, Giansante G, Valtorta F, Tsai JW, Zara F, Nieus T, Corradi A, Fassio A, Baldelli P, Benfenati F.

Cereb Cortex. 2019 May 1;29(5):2010-2033. doi: 10.1093/cercor/bhy079.


State-dependent representation of stimulus-evoked activity in high-density recordings of neural cultures.

Nieus T, D'Andrea V, Amin H, Di Marco S, Safaai H, Maccione A, Berdondini L, Panzeri S.

Sci Rep. 2018 Apr 3;8(1):5578. doi: 10.1038/s41598-018-23853-x.


PRRT2 controls neuronal excitability by negatively modulating Na+ channel 1.2/1.6 activity.

Fruscione F, Valente P, Sterlini B, Romei A, Baldassari S, Fadda M, Prestigio C, Giansante G, Sartorelli J, Rossi P, Rubio A, Gambardella A, Nieus T, Broccoli V, Fassio A, Baldelli P, Corradi A, Zara F, Benfenati F.

Brain. 2018 Apr 1;141(4):1000-1016. doi: 10.1093/brain/awy051.


The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis.

Maggi S, Balzani E, Lassi G, Garcia-Garcia C, Plano A, Espinoza S, Mus L, Tinarelli F, Nolan PM, Gainetdinov RR, Balci F, Nieus T, Tucci V.

Sci Rep. 2017 Dec 19;7(1):17765. doi: 10.1038/s41598-017-18130-2.


Fast wide-volume functional imaging of engineered in vitro brain tissues.

Palazzolo G, Moroni M, Soloperto A, Aletti G, Naldi G, Vassalli M, Nieus T, Difato F.

Sci Rep. 2017 Aug 17;7(1):8499. doi: 10.1038/s41598-017-08979-8.


Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks.

Lonardoni D, Amin H, Di Marco S, Maccione A, Berdondini L, Nieus T.

PLoS Comput Biol. 2017 Jul 27;13(7):e1005672. doi: 10.1371/journal.pcbi.1005672. eCollection 2017 Jul.


Inter-Synaptic Lateral Diffusion of GABAA Receptors Shapes Inhibitory Synaptic Currents.

de Luca E, Ravasenga T, Petrini EM, Polenghi A, Nieus T, Guazzi S, Barberis A.

Neuron. 2017 Jul 5;95(1):63-69.e5. doi: 10.1016/j.neuron.2017.06.022.


High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies.

Amin H, Nieus T, Lonardoni D, Maccione A, Berdondini L.

Sci Rep. 2017 May 26;7(1):2460. doi: 10.1038/s41598-017-02635-x.


Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.

Pennacchietti F, Vascon S, Nieus T, Rosillo C, Das S, Tyagarajan SK, Diaspro A, Del Bue A, Petrini EM, Barberis A, Cella Zanacchi F.

J Neurosci. 2017 Feb 15;37(7):1747-1756. doi: 10.1523/JNEUROSCI.0514-16.2016. Epub 2017 Jan 10.


Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays.

Amin H, Maccione A, Marinaro F, Zordan S, Nieus T, Berdondini L.

Front Neurosci. 2016 Mar 30;10:121. doi: 10.3389/fnins.2016.00121. eCollection 2016.


Corrigendum: Regulation of output spike patterns by phasic inhibition in cerebellar granule cells.

Nieus TR, Mapelli L, D'Angelo E.

Front Cell Neurosci. 2016 Feb 16;10:30. doi: 10.3389/fncel.2016.00030. eCollection 2016.


High-density MEA recordings unveil the dynamics of bursting events in Cell Cultures.

Lonardoni D, Di Marco S, Amin H, Maccione A, Berdondini L, Nieus T.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3763-6. doi: 10.1109/EMBC.2015.7319212.


Investigating cell culture dynamics combining high density recordings with dimensional reduction techniques.

Nieus T, Di Marco S, Maccione A, Amin H, Berdondini L.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3759-62. doi: 10.1109/EMBC.2015.7319211.


Characterizing the Input-Output Function of the Olfactory-Limbic Pathway in the Guinea Pig.

Breschi GL, Ciliberto C, Nieus T, Rosasco L, Taverna S, Chiappalone M, Pasquale V.

Comput Intell Neurosci. 2015;2015:359590. doi: 10.1155/2015/359590. Epub 2015 Jul 28.


Microelectronics, bioinformatics and neurocomputation for massive neuronal recordings in brain circuits with large scale multielectrode array probes.

Maccione A, Gandolfo M, Zordan S, Amin H, Di Marco S, Nieus T, Angotzi GN, Berdondini L.

Brain Res Bull. 2015 Oct;119(Pt B):118-26. doi: 10.1016/j.brainresbull.2015.07.008. Epub 2015 Jul 29. Review.


Functional Interaction between the Scaffold Protein Kidins220/ARMS and Neuronal Voltage-Gated Na+ Channels.

Cesca F, Satapathy A, Ferrea E, Nieus T, Benfenati F, Scholz-Starke J.

J Biol Chem. 2015 Jul 17;290(29):18045-55. doi: 10.1074/jbc.M115.654699. Epub 2015 Jun 2.


From 2D to 3D: novel nanostructured scaffolds to investigate signalling in reconstructed neuronal networks.

Bosi S, Rauti R, Laishram J, Turco A, Lonardoni D, Nieus T, Prato M, Scaini D, Ballerini L.

Sci Rep. 2015 Apr 24;5:9562. doi: 10.1038/srep09562.


Functional connectivity estimation over large networks at cellular resolution based on electrophysiological recordings and structural prior.

Ullo S, Nieus TR, Sona D, Maccione A, Berdondini L, Murino V.

Front Neuroanat. 2014 Nov 20;8:137. doi: 10.3389/fnana.2014.00137. eCollection 2014.


Integration of microstructured scaffolds, neurons, and multielectrode arrays.

Simi A, Amin H, Maccione A, Nieus T, Berdondini L.

Prog Brain Res. 2014;214:415-42. doi: 10.1016/B978-0-444-63486-3.00017-7. Review.


Regulation of output spike patterns by phasic inhibition in cerebellar granule cells.

Nieus TR, Mapelli L, D'Angelo E.

Front Cell Neurosci. 2014 Aug 25;8:246. doi: 10.3389/fncel.2014.00246. eCollection 2014. Erratum in: Front Cell Neurosci. 2016;10:30.


Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features.

Tucci V, Kleefstra T, Hardy A, Heise I, Maggi S, Willemsen MH, Hilton H, Esapa C, Simon M, Buenavista MT, McGuffin LJ, Vizor L, Dodero L, Tsaftaris S, Romero R, Nillesen WN, Vissers LE, Kempers MJ, Vulto-van Silfhout AT, Iqbal Z, Orlando M, Maccione A, Lassi G, Farisello P, Contestabile A, Tinarelli F, Nieus T, Raimondi A, Greco B, Cantatore D, Gasparini L, Berdondini L, Bifone A, Gozzi A, Wells S, Nolan PM.

J Clin Invest. 2014 Apr;124(4):1468-82. doi: 10.1172/JCI70372. Epub 2014 Mar 10.


Dynamics of action potential firing in electrically connected striatal fast-spiking interneurons.

Russo G, Nieus TR, Maggi S, Taverna S.

Front Cell Neurosci. 2013 Nov 14;7:209. doi: 10.3389/fncel.2013.00209. eCollection 2013.


Large-scale, high-resolution electrophysiological imaging of field potentials in brain slices with microelectronic multielectrode arrays.

Ferrea E, Maccione A, Medrihan L, Nieus T, Ghezzi D, Baldelli P, Benfenati F, Berdondini L.

Front Neural Circuits. 2012 Nov 14;6:80. doi: 10.3389/fncir.2012.00080. eCollection 2012.


Loss of Gnas imprinting differentially affects REM/NREM sleep and cognition in mice.

Lassi G, Ball ST, Maggi S, Colonna G, Nieus T, Cero C, Bartolomucci A, Peters J, Tucci V.

PLoS Genet. 2012;8(5):e1002706. doi: 10.1371/journal.pgen.1002706. Epub 2012 May 10.


Site-specific synapsin I phosphorylation participates in the expression of post-tetanic potentiation and its enhancement by BDNF.

Valente P, Casagrande S, Nieus T, Verstegen AM, Valtorta F, Benfenati F, Baldelli P.

J Neurosci. 2012 Apr 25;32(17):5868-79. doi: 10.1523/JNEUROSCI.5275-11.2012.


Multiscale functional connectivity estimation on low-density neuronal cultures recorded by high-density CMOS Micro Electrode Arrays.

Maccione A, Garofalo M, Nieus T, Tedesco M, Berdondini L, Martinoia S.

J Neurosci Methods. 2012 Jun 15;207(2):161-71. doi: 10.1016/j.jneumeth.2012.04.002. Epub 2012 Apr 9.


Emergent functional properties of neuronal networks with controlled topology.

Marconi E, Nieus T, Maccione A, Valente P, Simi A, Messa M, Dante S, Baldelli P, Berdondini L, Benfenati F.

PLoS One. 2012;7(4):e34648. doi: 10.1371/journal.pone.0034648. Epub 2012 Apr 6.


Synaptic and extrasynaptic origin of the excitation/inhibition imbalance in the hippocampus of synapsin I/II/III knockout mice.

Farisello P, Boido D, Nieus T, Medrihan L, Cesca F, Valtorta F, Baldelli P, Benfenati F.

Cereb Cortex. 2013 Mar;23(3):581-93. doi: 10.1093/cercor/bhs041. Epub 2012 Feb 24.


Influence of GABAAR monoliganded states on GABAergic responses.

Petrini EM, Nieus T, Ravasenga T, Succol F, Guazzi S, Benfenati F, Barberis A.

J Neurosci. 2011 Feb 2;31(5):1752-61. doi: 10.1523/JNEUROSCI.1453-10.2011.


A realistic large-scale model of the cerebellum granular layer predicts circuit spatio-temporal filtering properties.

Solinas S, Nieus T, D'Angelo E.

Front Cell Neurosci. 2010 May 14;4:12. doi: 10.3389/fncel.2010.00012. eCollection 2010.


Experimental Investigation on Spontaneously Active Hippocampal Cultures Recorded by Means of High-Density MEAs: Analysis of the Spatial Resolution Effects.

Maccione A, Gandolfo M, Tedesco M, Nieus T, Imfeld K, Martinoia S, Berdondini L.

Front Neuroeng. 2010 May 10;3:4. doi: 10.3389/fneng.2010.00004. eCollection 2010.


How synaptic release probability shapes neuronal transmission: information-theoretic analysis in a cerebellar granule cell.

Arleo A, Nieus T, Bezzi M, D'Errico A, D'Angelo E, Coenen OJ.

Neural Comput. 2010 Aug;22(8):2031-58. doi: 10.1162/NECO_a_00006-Arleo.


Low-frequency stimulation enhances burst activity in cortical cultures during development.

Bologna LL, Nieus T, Tedesco M, Chiappalone M, Benfenati F, Martinoia S.

Neuroscience. 2010 Feb 3;165(3):692-704. doi: 10.1016/j.neuroscience.2009.11.018. Epub 2009 Nov 14.


Evaluation of the performance of information theory-based methods and cross-correlation to estimate the functional connectivity in cortical networks.

Garofalo M, Nieus T, Massobrio P, Martinoia S.

PLoS One. 2009 Aug 4;4(8):e6482. doi: 10.1371/journal.pone.0006482.


Tonic activation of GABAB receptors reduces release probability at inhibitory connections in the cerebellar glomerulus.

Mapelli L, Rossi P, Nieus T, D'Angelo E.

J Neurophysiol. 2009 Jun;101(6):3089-99. doi: 10.1152/jn.91190.2008. Epub 2009 Apr 1.


Event-driven simulation of cerebellar granule cells.

Carrillo RR, Ros E, Tolu S, Nieus T, D'Angelo E.

Biosystems. 2008 Oct-Nov;94(1-2):10-7. doi: 10.1016/j.biosystems.2008.05.007. Epub 2008 Jun 20.


LTP regulates burst initiation and frequency at mossy fiber-granule cell synapses of rat cerebellum: experimental observations and theoretical predictions.

Nieus T, Sola E, Mapelli J, Saftenku E, Rossi P, D'Angelo E.

J Neurophysiol. 2006 Feb;95(2):686-99. Epub 2005 Oct 5.


Role of calcium binding proteins in the control of cerebellar granule cell neuronal excitability: experimental and modeling studies.

Gall D, Roussel C, Nieus T, Cheron G, Servais L, D'Angelo E, Schiffmann SN.

Prog Brain Res. 2005;148:321-8. Review.


Long-term potentiation of synaptic transmission at the mossy fiber-granule cell relay of cerebellum.

D'Angelo E, Rossi P, Gall D, Prestori F, Nieus T, Maffei A, Sola E.

Prog Brain Res. 2005;148:69-80. Review.


Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

D'Angelo E, Nieus T, Maffei A, Armano S, Rossi P, Taglietti V, Fontana A, Naldi G.

J Neurosci. 2001 Feb 1;21(3):759-70.

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