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Items: 49

1.

Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3.

Schneider T, Hung LH, Aziz M, Wilmen A, Thaum S, Wagner J, Janowski R, Müller S, Schreiner S, Friedhoff P, Hüttelmaier S, Niessing D, Sattler M, Schlundt A, Bindereif A.

Nat Commun. 2019 May 22;10(1):2266. doi: 10.1038/s41467-019-09769-8.

2.

Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains.

Heber S, Gáspár I, Tants JN, Günther J, Moya SMF, Janowski R, Ephrussi A, Sattler M, Niessing D.

Nat Commun. 2019 Apr 10;10(1):1659. doi: 10.1038/s41467-019-09655-3.

3.

Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.

Fuenzalida-Werner JP, Janowski R, Mishra K, Weidenfeld I, Niessing D, Ntziachristos V, Stiel AC.

J Struct Biol. 2018 Dec;204(3):519-522. doi: 10.1016/j.jsb.2018.09.013. Epub 2018 Oct 1.

PMID:
30287387
4.

A high-content screen for small-molecule regulators of epithelial cell-adhesion molecule (EpCAM) cleavage yields a robust inhibitor.

Tretter JY, Schorpp K, Luxenburger E, Trambauer J, Steiner H, Hadian K, Gires O, Niessing D.

J Biol Chem. 2018 Jun 8;293(23):8994-9005. doi: 10.1074/jbc.RA118.002776. Epub 2018 Apr 26.

5.

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.

Hofweber M, Hutten S, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D.

Cell. 2018 Apr 19;173(3):706-719.e13. doi: 10.1016/j.cell.2018.03.004.

6.

Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.

Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V.

Nat Commun. 2018 Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1.

7.

PURA syndrome: clinical delineation and genotype-phenotype study in 32 individuals with review of published literature.

Reijnders MRF, Janowski R, Alvi M, Self JE, van Essen TJ, Vreeburg M, Rouhl RPW, Stevens SJC, Stegmann APA, Schieving J, Pfundt R, van Dijk K, Smeets E, Stumpel CTRM, Bok LA, Cobben JM, Engelen M, Mansour S, Whiteford M, Chandler KE, Douzgou S, Cooper NS, Tan EC, Foo R, Lai AHM, Rankin J, Green A, Lönnqvist T, Isohanni P, Williams S, Ruhoy I, Carvalho KS, Dowling JJ, Lev DL, Sterbova K, Lassuthova P, Neupauerová J, Waugh JL, Keros S, Clayton-Smith J, Smithson SF, Brunner HG, van Hoeckel C, Anderson M, Clowes VE, Siu VM, Ddd Study T, Selber P, Leventer RJ, Nellaker C, Niessing D, Hunt D, Baralle D.

J Med Genet. 2018 Feb;55(2):104-113. doi: 10.1136/jmedgenet-2017-104946. Epub 2017 Nov 2. Review.

8.

mRNA transport in fungal top models.

Niessing D, Jansen RP, Pohlmann T, Feldbrügge M.

Wiley Interdiscip Rev RNA. 2018 Jan;9(1). doi: 10.1002/wrna.1453. Epub 2017 Oct 10. Review.

PMID:
28994236
9.

Evidence for Complex Formation of the Bacillus cereus Haemolysin BL Components in Solution.

Tausch F, Dietrich R, Schauer K, Janowski R, Niessing D, Märtlbauer E, Jessberger N.

Toxins (Basel). 2017 Sep 16;9(9). pii: E288. doi: 10.3390/toxins9090288.

10.

Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.

Schlundt A, Buchner S, Janowski R, Heydenreich T, Heermann R, Lassak J, Geerlof A, Stehle R, Niessing D, Jung K, Sattler M.

Sci Rep. 2017 Apr 21;7(1):1051. doi: 10.1038/s41598-017-01031-9.

11.

Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.

Edelmann FT, Schlundt A, Heym RG, Jenner A, Niedner-Boblenz A, Syed MI, Paillart JC, Stehle R, Janowski R, Sattler M, Jansen RP, Niessing D.

Nat Struct Mol Biol. 2017 Feb;24(2):152-161. doi: 10.1038/nsmb.3351. Epub 2017 Jan 16.

PMID:
28092367
12.

Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.

Janowski R, Scanu S, Niessing D, Madl T.

Acta Crystallogr F Struct Biol Commun. 2016 Oct 1;72(Pt 10):743-749. Epub 2016 Sep 22.

13.

Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.

Janowski R, Heinz GA, Schlundt A, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessing D, Heissmeyer V, Sattler M.

Nat Commun. 2016 Mar 24;7:11032. doi: 10.1038/ncomms11032.

14.

RNA recognition by Roquin in posttranscriptional gene regulation.

Schlundt A, Niessing D, Heissmeyer V, Sattler M.

Wiley Interdiscip Rev RNA. 2016 Jul;7(4):455-69. doi: 10.1002/wrna.1333. Epub 2016 Feb 4. Review.

PMID:
26844532
15.

Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.

Weber J, Bao H, Hartlmüller C, Wang Z, Windhager A, Janowski R, Madl T, Jin P, Niessing D.

Elife. 2016 Jan 8;5. pii: e11297. doi: 10.7554/eLife.11297.

16.

Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.

Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D.

Sci Rep. 2016 Jan 7;6:18934. doi: 10.1038/srep18934.

17.

Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity.

Morgen M, Jöst C, Malz M, Janowski R, Niessing D, Klein CD, Gunkel N, Miller AK.

ACS Chem Biol. 2016 Apr 15;11(4):1001-11. doi: 10.1021/acschembio.5b00755. Epub 2016 Jan 19.

PMID:
26686773
18.

ASH1 mRNP-core factors form stable complexes in absence of cargo RNA at physiological conditions.

Edelmann FT, Niedner A, Niessing D.

RNA Biol. 2015;12(3):233-7. doi: 10.1080/15476286.2015.1017217.

19.

Of social molecules: The interactive assembly of ASH1 mRNA-transport complexes in yeast.

Niedner A, Edelmann FT, Niessing D.

RNA Biol. 2014;11(8):998-1009. doi: 10.4161/rna.29946. Epub 2014 Oct 31. Review.

20.

mRNA transport meets membrane traffic.

Jansen RP, Niessing D, Baumann S, Feldbrügge M.

Trends Genet. 2014 Sep;30(9):408-17. doi: 10.1016/j.tig.2014.07.002. Epub 2014 Aug 7. Review.

PMID:
25110341
21.

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.

Schlundt A, Heinz GA, Janowski R, Geerlof A, Stehle R, Heissmeyer V, Niessing D, Sattler M.

Nat Struct Mol Biol. 2014 Aug;21(8):671-8. doi: 10.1038/nsmb.2855. Epub 2014 Jul 13.

PMID:
25026077
22.

In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation.

Heym RG, Zimmermann D, Edelmann FT, Israel L, Ökten Z, Kovar DR, Niessing D.

J Cell Biol. 2013 Dec 23;203(6):971-84. doi: 10.1083/jcb.201302095.

23.

Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.

Velvarska H, Niessing D.

PLoS One. 2013 Dec 10;8(12):e82065. doi: 10.1371/journal.pone.0082065. eCollection 2013.

24.

Role of Loc1p in assembly and reorganization of nuclear ASH1 messenger ribonucleoprotein particles in yeast.

Niedner A, Müller M, Moorthy BT, Jansen RP, Niessing D.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):E5049-58. doi: 10.1073/pnas.1315289111. Epub 2013 Dec 9.

25.

Purification, crystallization and preliminary crystallographic analysis of the globular domain of the human type V myosin Myo5a.

Velvarska H, Niessing D.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1220-3. doi: 10.1107/S1744309113025578. Epub 2013 Oct 17.

26.

Structural features of Argonaute-GW182 protein interactions.

Pfaff J, Hennig J, Herzog F, Aebersold R, Sattler M, Niessing D, Meister G.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3770-9. doi: 10.1073/pnas.1308510110. Epub 2013 Sep 16.

27.

Production of pure and functional RNA for in vitro reconstitution experiments.

Edelmann FT, Niedner A, Niessing D.

Methods. 2014 Feb;65(3):333-41. doi: 10.1016/j.ymeth.2013.08.034. Epub 2013 Sep 8. Review.

28.

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation.

Walcher T, Xie Q, Sun J, Irmler M, Beckers J, Öztürk T, Niessing D, Stoykova A, Cvekl A, Ninkovic J, Götz M.

Development. 2013 Mar;140(5):1123-36. doi: 10.1242/dev.082875.

29.

Purification, crystallization and preliminary crystallographic analysis of Kar9p from Saccharomyces cerevisiae.

Hüls D, Niessing D.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1251-4. doi: 10.1107/S1744309112036342. Epub 2012 Sep 29.

30.

Assembly of mRNA-protein complexes for directional mRNA transport in eukaryotes--an overview.

Jansen RP, Niessing D.

Curr Protein Pept Sci. 2012 Jun;13(4):284-93. Review.

31.

Drosophila Pur-α binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte.

Aumiller V, Graebsch A, Kremmer E, Niessing D, Förstemann K.

RNA Biol. 2012 May;9(5):633-43. doi: 10.4161/rna.19760. Epub 2012 May 1.

PMID:
22614836
32.

Post-translational modifications regulate assembly of early spindle orientation complex in yeast.

Hüls D, Storchova Z, Niessing D.

J Biol Chem. 2012 May 11;287(20):16238-45. doi: 10.1074/jbc.M112.347872. Epub 2012 Mar 29.

33.

Principles of mRNA transport in yeast.

Heym RG, Niessing D.

Cell Mol Life Sci. 2012 Jun;69(11):1843-53. doi: 10.1007/s00018-011-0902-4. Epub 2011 Dec 13. Review.

34.

A cytoplasmic complex mediates specific mRNA recognition and localization in yeast.

Müller M, Heym RG, Mayer A, Kramer K, Schmid M, Cramer P, Urlaub H, Jansen RP, Niessing D.

PLoS Biol. 2011 Apr;9(4):e1000611. doi: 10.1371/journal.pbio.1000611. Epub 2011 Apr 19.

35.

Of bits and bugs--on the use of bioinformatics and a bacterial crystal structure to solve a eukaryotic repeat-protein structure.

Graebsch A, Roche S, Kostrewa D, Söding J, Niessing D.

PLoS One. 2010 Oct 14;5(10):e13402. doi: 10.1371/journal.pone.0013402.

36.

The structure of the Myo4p globular tail and its function in ASH1 mRNA localization.

Heuck A, Fetka I, Brewer DN, Hüls D, Munson M, Jansen RP, Niessing D.

J Cell Biol. 2010 May 3;189(3):497-510. doi: 10.1083/jcb.201002076.

37.

X-ray structure of Pur-alpha reveals a Whirly-like fold and an unusual nucleic-acid binding surface.

Graebsch A, Roche S, Niessing D.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18521-6. doi: 10.1073/pnas.0907990106. Epub 2009 Oct 21.

38.

Formation of She2p tetramers is required for mRNA binding, mRNP assembly, and localization.

Müller M, Richter K, Heuck A, Kremmer E, Buchner J, Jansen RP, Niessing D.

RNA. 2009 Nov;15(11):2002-12. doi: 10.1261/rna.1753309. Epub 2009 Aug 26.

39.

Helical growth of the Arabidopsis mutant tortifolia2 does not depend on cell division patterns but involves handed twisting of isolated cells.

Buschmann H, Hauptmann M, Niessing D, Lloyd CW, Schäffner AR.

Plant Cell. 2009 Jul;21(7):2090-106. doi: 10.1105/tpc.108.061242. Epub 2009 Jul 28.

40.

Nuclear transit of the RNA-binding protein She2 is required for translational control of localized ASH1 mRNA.

Du TG, Jellbauer S, Müller M, Schmid M, Niessing D, Jansen RP.

EMBO Rep. 2008 Aug;9(8):781-7. doi: 10.1038/embor.2008.112. Epub 2008 Jun 20.

41.

Monomeric myosin V uses two binding regions for the assembly of stable translocation complexes.

Heuck A, Du TG, Jellbauer S, Richter K, Kruse C, Jaklin S, Müller M, Buchner J, Jansen RP, Niessing D.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19778-83. Epub 2007 Dec 4.

42.

Directional mRNA transport in eukaryotes: lessons from yeast.

Müller M, Heuck A, Niessing D.

Cell Mol Life Sci. 2007 Jan;64(2):171-80. Review.

PMID:
17131056
43.

She2p is a novel RNA binding protein with a basic helical hairpin motif.

Niessing D, Hüttelmaier S, Zenklusen D, Singer RH, Burley SK.

Cell. 2004 Nov 12;119(4):491-502.

44.

bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish.

Leung T, Bischof J, Söll I, Niessing D, Zhang D, Ma J, Jäckle H, Driever W.

Development. 2003 Aug;130(16):3639-49.

45.

Bicoid associates with the 5'-cap-bound complex of caudal mRNA and represses translation.

Niessing D, Blanke S, Jäckle H.

Genes Dev. 2002 Oct 1;16(19):2576-82.

46.

Homeodomain position 54 specifies transcriptional versus translational control by Bicoid.

Niessing D, Driever W, Sprenger F, Taubert H, Jäckle H, Rivera-Pomar R.

Mol Cell. 2000 Feb;5(2):395-401.

48.

A cascade of transcriptional control leading to axis determination in Drosophila.

Niessing D, Rivera-Pomar R, La Rosée A, Häder T, Schöck F, Purnell BA, Jäckle H.

J Cell Physiol. 1997 Nov;173(2):162-7. Review. No abstract available.

PMID:
9365516
49.

RNA binding and translational suppression by bicoid.

Rivera-Pomar R, Niessing D, Schmidt-Ott U, Gehring WJ, Jäckle H.

Nature. 1996 Feb 22;379(6567):746-9.

PMID:
8602224

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