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Items: 43

1.

Redox signals at the ER-mitochondria interface control melanoma progression.

Zhang X, Gibhardt CS, Will T, Stanisz H, Körbel C, Mitkovski M, Stejerean I, Cappello S, Pacheu-Grau D, Dudek J, Tahbaz N, Mina L, Simmen T, Laschke MW, Menger MD, Schön MP, Helms V, Niemeyer BA, Rehling P, Vultur A, Bogeski I.

EMBO J. 2019 Jul 15:e100871. doi: 10.15252/embj.2018100871. [Epub ahead of print]

PMID:
31304984
2.

Stepping out of the shadow: STIM2 promotes IL-3-induced cytokine release.

Alansary D, Niemeyer BA.

Sci Signal. 2019 Apr 9;12(576). pii: eaax0210. doi: 10.1126/scisignal.aax0210. Review.

PMID:
30967511
3.

Reaction-diffusion model for STIM-ORAI interaction: The role of ROS and mutations.

Schmidt B, Alansary D, Bogeski I, Niemeyer BA, Rieger H.

J Theor Biol. 2019 Jun 7;470:64-75. doi: 10.1016/j.jtbi.2019.02.010. Epub 2019 Mar 7.

PMID:
30853394
4.

Modulation of intracellular calcium signaling by microRNA-34a-5p.

Diener C, Hart M, Alansary D, Poth V, Walch-Rückheim B, Menegatti J, Grässer F, Fehlmann T, Rheinheimer S, Niemeyer BA, Lenhof HP, Keller A, Meese E.

Cell Death Dis. 2018 Sep 27;9(10):1008. doi: 10.1038/s41419-018-1050-7.

5.

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.

Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M.

Nat Med. 2018 Aug;24(8):1192-1203. doi: 10.1038/s41591-018-0095-6. Epub 2018 Jul 9.

PMID:
29988124
6.

Profiling calcium signals of in vitro polarized human effector CD4+ T cells.

Kircher S, Merino-Wong M, Niemeyer BA, Alansary D.

Biochim Biophys Acta Mol Cell Res. 2018 Jun;1865(6):932-943. doi: 10.1016/j.bbamcr.2018.04.001. Epub 2018 Apr 5.

7.

Cross-linking of Orai1 channels by STIM proteins.

Zhou Y, Nwokonko RM, Cai X, Loktionova NA, Abdulqadir R, Xin P, Niemeyer BA, Wang Y, Trebak M, Gill DL.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3398-E3407. doi: 10.1073/pnas.1720810115. Epub 2018 Mar 26.

8.

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.

Zhou X, Friedmann KS, Lyrmann H, Zhou Y, Schoppmeyer R, Knörck A, Mang S, Hoxha C, Angenendt A, Backes CS, Mangerich C, Zhao R, Cappello S, Schwär G, Hässig C, Neef M, Bufe B, Zufall F, Kruse K, Niemeyer BA, Lis A, Qu B, Kummerow C, Schwarz EC, Hoth M.

J Physiol. 2018 Jul;596(14):2681-2698. doi: 10.1113/JP274964. Epub 2018 Mar 12.

9.

The STIM-Orai Pathway: Regulation of STIM and Orai by Thiol Modifications.

Niemeyer BA.

Adv Exp Med Biol. 2017;993:99-116. doi: 10.1007/978-3-319-57732-6_6. Review.

PMID:
28900911
10.

Large dense-core vesicle exocytosis from mouse dorsal root ganglion neurons is regulated by neuropeptide Y.

Bost A, Shaib AH, Schwarz Y, Niemeyer BA, Becherer U.

Neuroscience. 2017 Mar 27;346:1-13. doi: 10.1016/j.neuroscience.2017.01.006. Epub 2017 Jan 13.

PMID:
28089870
11.

Thiol dependent intramolecular locking of Orai1 channels.

Alansary D, Schmidt B, Dörr K, Bogeski I, Rieger H, Kless A, Niemeyer BA.

Sci Rep. 2016 Sep 14;6:33347. doi: 10.1038/srep33347.

12.

Visualizing Quantum Dot Labeled ORAI1 Proteins in Intact Cells Via Correlative Light and Electron Microscopy.

Peckys DB, Alansary D, Niemeyer BA, de Jonge N.

Microsc Microanal. 2016 Aug;22(4):902-12. doi: 10.1017/S1431927616011491. Epub 2016 Aug 12.

PMID:
27515473
13.

A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels.

Saul S, Gibhardt CS, Schmidt B, Lis A, Pasieka B, Conrad D, Jung P, Gaupp R, Wonnenberg B, Diler E, Stanisz H, Vogt T, Schwarz EC, Bischoff M, Herrmann M, Tschernig T, Kappl R, Rieger H, Niemeyer BA, Bogeski I.

Sci Signal. 2016 Mar 8;9(418):ra26. doi: 10.1126/scisignal.aaf1639.

PMID:
26956485
14.

Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry.

Dörr K, Kilch T, Kappel S, Alansary D, Schwär G, Niemeyer BA, Peinelt C.

Sci Signal. 2016 Mar 8;9(418):ra25. doi: 10.1126/scisignal.aaa9913.

PMID:
26956484
15.

Changing calcium: CRAC channel (STIM and Orai) expression, splicing, and posttranslational modifiers.

Niemeyer BA.

Am J Physiol Cell Physiol. 2016 May 1;310(9):C701-9. doi: 10.1152/ajpcell.00034.2016. Epub 2016 Feb 24. Review.

16.

A STIM2 splice variant negatively regulates store-operated calcium entry.

Miederer AM, Alansary D, Schwär G, Lee PH, Jung M, Helms V, Niemeyer BA.

Nat Commun. 2015 Apr 21;6:6899. doi: 10.1038/ncomms7899.

17.

Facilitation of Orai3 targeting and store-operated function by Orai1.

Alansary D, Bogeski I, Niemeyer BA.

Biochim Biophys Acta. 2015 Jul;1853(7):1541-50. doi: 10.1016/j.bbamcr.2015.03.007. Epub 2015 Mar 17.

18.

Redox regulation of ion channels.

Bogeski I, Niemeyer BA.

Antioxid Redox Signal. 2014 Aug 20;21(6):859-62. doi: 10.1089/ars.2014.6019. Epub 2014 Jul 8.

19.

Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry.

Stanisz H, Saul S, Müller CS, Kappl R, Niemeyer BA, Vogt T, Hoth M, Roesch A, Bogeski I.

Pigment Cell Melanoma Res. 2014 May;27(3):442-53. doi: 10.1111/pcmr.12222. Epub 2014 Mar 7.

PMID:
24472175
20.

The neglected CRAC proteins: Orai2, Orai3, and STIM2.

Hoth M, Niemeyer BA.

Curr Top Membr. 2013;71:237-71. doi: 10.1016/B978-0-12-407870-3.00010-X. Review.

PMID:
23890118
21.

Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1.

Kilch T, Alansary D, Peglow M, Dörr K, Rychkov G, Rieger H, Peinelt C, Niemeyer BA.

J Biol Chem. 2013 Jan 18;288(3):1653-64. doi: 10.1074/jbc.M112.417246. Epub 2012 Dec 4.

22.

ORMDL3 modulates store-operated calcium entry and lymphocyte activation.

Carreras-Sureda A, Cantero-Recasens G, Rubio-Moscardo F, Kiefer K, Peinelt C, Niemeyer BA, Valverde MA, Vicente R.

Hum Mol Genet. 2013 Feb 1;22(3):519-30. doi: 10.1093/hmg/dds450. Epub 2012 Oct 25.

23.

ROS and SOCE: recent advances and controversies in the regulation of STIM and Orai.

Bogeski I, Kilch T, Niemeyer BA.

J Physiol. 2012 Sep 1;590(17):4193-200. doi: 10.1113/jphysiol.2012.230565. Epub 2012 May 21. Review.

24.

Can we see PIP(3) and hydrogen peroxide with a single probe?

Mishina NM, Bogeski I, Bolotin DA, Hoth M, Niemeyer BA, Schultz C, Zagaynova EV, Lukyanov S, Belousov VV.

Antioxid Redox Signal. 2012 Aug 1;17(3):505-12. doi: 10.1089/ars.2012.4574. Epub 2012 Apr 10.

PMID:
22369174
25.

ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes.

Stanisz H, Stark A, Kilch T, Schwarz EC, Müller CS, Peinelt C, Hoth M, Niemeyer BA, Vogt T, Bogeski I.

J Invest Dermatol. 2012 May;132(5):1443-51. doi: 10.1038/jid.2011.478. Epub 2012 Feb 9.

26.

Excitable T cells: Ca(v)1.4 channel contributions and controversies.

Niemeyer BA, Hoth M.

Immunity. 2011 Sep 23;35(3):315-7. doi: 10.1016/j.immuni.2011.09.001.

27.

Redox regulation of calcium ion channels: chemical and physiological aspects.

Bogeski I, Kappl R, Kummerow C, Gulaboski R, Hoth M, Niemeyer BA.

Cell Calcium. 2011 Nov;50(5):407-23. doi: 10.1016/j.ceca.2011.07.006. Epub 2011 Sep 17. Review.

PMID:
21930299
28.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

Quintana A, Pasche M, Junker C, Al-Ansary D, Rieger H, Kummerow C, Nuñez L, Villalobos C, Meraner P, Becherer U, Rettig J, Niemeyer BA, Hoth M.

EMBO J. 2011 Aug 16;30(19):3895-912. doi: 10.1038/emboj.2011.289.

29.

Pharmacology of ORAI channels as a tool to understand their physiological functions.

Bogeski I, Al-Ansary D, Qu B, Niemeyer BA, Hoth M, Peinelt C.

Expert Rev Clin Pharmacol. 2010 May;3(3):291-303. doi: 10.1586/ecp.10.23.

PMID:
22111611
30.

Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling.

Bogeski I, Kummerow C, Al-Ansary D, Schwarz EC, Koehler R, Kozai D, Takahashi N, Peinelt C, Griesemer D, Bozem M, Mori Y, Hoth M, Niemeyer BA.

Sci Signal. 2010 Mar 30;3(115):ra24. doi: 10.1126/scisignal.2000672.

31.

ATP modulates Ca2+ uptake by TRPV6 and is counteracted by isoform-specific phosphorylation.

Al-Ansary D, Bogeski I, Disteldorf BM, Becherer U, Niemeyer BA.

FASEB J. 2010 Feb;24(2):425-35. doi: 10.1096/fj.09-141481. Epub 2009 Oct 5.

PMID:
19805577
32.

TRPV6.

Wissenbach U, Niemeyer BA.

Handb Exp Pharmacol. 2007;(179):221-34. Review.

PMID:
17217060
33.

Trafficking and assembly of the cold-sensitive TRPM8 channel.

Erler I, Al-Ansary DM, Wissenbach U, Wagner TF, Flockerzi V, Niemeyer BA.

J Biol Chem. 2006 Dec 15;281(50):38396-404. Epub 2006 Oct 25.

34.

TRPV6 potentiates calcium-dependent cell proliferation.

Schwarz EC, Wissenbach U, Niemeyer BA, Strauss B, Philipp SE, Flockerzi V, Hoth M.

Cell Calcium. 2006 Feb;39(2):163-73. Epub 2005 Dec 13.

PMID:
16356545
35.

Structure-function analysis of TRPV channels.

Niemeyer BA.

Naunyn Schmiedebergs Arch Pharmacol. 2005 Apr;371(4):285-94. Review.

PMID:
15889240
36.

Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat.

Erler I, Hirnet D, Wissenbach U, Flockerzi V, Niemeyer BA.

J Biol Chem. 2004 Aug 13;279(33):34456-63. Epub 2004 Jun 10.

37.

TRP channels as potential drug targets.

Wissenbach U, Niemeyer BA, Flockerzi V.

Biol Cell. 2004 Feb;96(1):47-54. Review.

PMID:
15093127
38.

Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability.

Bhattacharya S, Stewart BA, Niemeyer BA, Burgess RW, McCabe BD, Lin P, Boulianne G, O'Kane CJ, Schwarz TL.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13867-72. Epub 2002 Oct 3.

39.

Ion channels in health and disease. 83rd Boehringer Ingelheim Fonds International Titisee Conference.

Niemeyer BA, Mery L, Zawar C, Suckow A, Monje F, Pardo LA, Stuhmer W, Flockerzi V, Hoth M.

EMBO Rep. 2001 Jul;2(7):568-73. No abstract available.

40.

Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancer.

Wissenbach U, Niemeyer BA, Fixemer T, Schneidewind A, Trost C, Cavalie A, Reus K, Meese E, Bonkhoff H, Flockerzi V.

J Biol Chem. 2001 Jun 1;276(22):19461-8. Epub 2001 Feb 2.

41.

Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin.

Niemeyer BA, Bergs C, Wissenbach U, Flockerzi V, Trost C.

Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3600-5.

43.

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

Niemeyer BA, Suzuki E, Scott K, Jalink K, Zuker CS.

Cell. 1996 May 31;85(5):651-9.

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