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Diagnostic accuracy of alpha-defensin enzyme-linked immunosorbent assay in the clinical evaluation of painful hip and knee arthroplasty with possible prosthetic joint infection: a prospective study of 202 cases.

Kleiss S, Jandl NM, Novo de Oliveira A, Rüther W, Niemeier A.

Bone Joint J. 2019 Aug;101-B(8):970-977. doi: 10.1302/0301-620X.101B8.BJJ-2018-1390.R2.


Hip abductor tendon pathology visualized by 1.5 versus 3. 0 Tesla MRIs.

Oehler N, Ruby JK, Strahl A, Maas R, Ruether W, Niemeier A.

Arch Orthop Trauma Surg. 2019 Jun 26. doi: 10.1007/s00402-019-03228-1. [Epub ahead of print]


General synovitis score and immunologic synovitis score reflect clinical disease activity in patients with advanced stage rheumatoid arthritis.

Schmidt T, Najm A, Mussawy H, Burghardt R, Oehler N, Krenn V, Rüther W, Niemeier A.

Sci Rep. 2019 Jun 11;9(1):8448. doi: 10.1038/s41598-019-44895-9.


The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: a systematic literature review.

Burghardt RD, Kazim MA, Rüther W, Niemeier A, Strahl A.

Rheumatol Int. 2019 May;39(5):793-804. doi: 10.1007/s00296-019-04284-x. Epub 2019 Mar 21. Review.


Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration.

Hawellek T, Hubert J, Hischke S, Krause M, Bertrand J, Schmidt BC, Kronz A, Püschel K, Rüther W, Niemeier A.

Arthritis Res Ther. 2018 May 30;20(1):104. doi: 10.1186/s13075-018-1595-y.


Autologous bridging of rotator cuff tears with a hamstring tendon patch. A cadaver feasibility study and biomechanical testing.

Kircher J, Schmidt F, Hawellek T, Hubert J, Hedtmann A, Püschel K, Hahn M, Niemeier A.

Clin Biomech (Bristol, Avon). 2018 Jul;56:36-39. doi: 10.1016/j.clinbiomech.2018.05.004. Epub 2018 May 19. No abstract available.


[Arthur Vick Prize 2017 of the German Society of Orthopaedic Rheumatology].

Bause L, Niemeier A, Krenn V.

Z Rheumatol. 2018 Mar;77(2):168-174. doi: 10.1007/s00393-018-0433-6. Review. German.


Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling.

Bartelt A, Behler-Janbeck F, Beil FT, Koehne T, Müller B, Schmidt T, Heine M, Ochs L, Yilmaz T, Dietrich M, Tuckermann JP, Amling M, Herz J, Schinke T, Heeren J, Niemeier A.

Bone Res. 2018 Feb 26;6:4. doi: 10.1038/s41413-017-0006-3. eCollection 2018.


Labral calcification in end-stage osteoarthritis of the hip correlates with pain and clinical function.

Hubert J, Hawellek T, Moe M, Hischke S, Krause M, Rolvien T, Schmidt T, Rüther W, Niemeier A.

J Orthop Res. 2018 Apr;36(4):1248-1255. doi: 10.1002/jor.23736. Epub 2017 Oct 9.


Differential effects of Calca-derived peptides in male mice with diet-induced obesity.

Bartelt A, Jeschke A, Müller B, Gaziano I, Morales M, Yorgan T, Heckt T, Heine M, Gagel RF, Emeson RB, Amling M, Niemeier A, Heeren J, Schinke T, Keller J.

PLoS One. 2017 Jun 30;12(6):e0180547. doi: 10.1371/journal.pone.0180547. eCollection 2017.


Quantification of Bone Fatty Acid Metabolism and Its Regulation by Adipocyte Lipoprotein Lipase.

Bartelt A, Koehne T, Tödter K, Reimer R, Müller B, Behler-Janbeck F, Heeren J, Scheja L, Niemeier A.

Int J Mol Sci. 2017 Jun 13;18(6). pii: E1264. doi: 10.3390/ijms18061264.


Microcalcification of lumbar spine intervertebral discs and facet joints is associated with cartilage degeneration, but differs in prevalence and its relation to age.

Hawellek T, Hubert J, Hischke S, Rolvien T, Krause M, Püschel K, Rüther W, Niemeier A.

J Orthop Res. 2017 Dec;35(12):2692-2699. doi: 10.1002/jor.23591. Epub 2017 May 18.


Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.

Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J.

Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010.


Symptomatic Os VesalianumA Case Report and Review of the Literature.

Beil FT, Burghardt RD, Strahl A, Ruether W, Niemeier A.

J Am Podiatr Med Assoc. 2017 Mar;107(2):162-165. doi: 10.7547/15-160. Review.


[Total Joint Replacement and Return to Sports].

Oehler N, Schmidt T, Niemeier A.

Sportverletz Sportschaden. 2016 Dec;30(4):195-203. Epub 2016 Dec 16. Review. German.


Hyaline cartilage calcification of the first metatarsophalangeal joint is associated with osteoarthritis but independent of age and BMI.

Hubert J, Hawellek T, Hischke S, Bertrand J, Krause M, Püschel K, Rüther W, Niemeier A.

BMC Musculoskelet Disord. 2016 Nov 15;17(1):474.


Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder.

Hawellek T, Hubert J, Hischke S, Krause M, Bertrand J, Pap T, Püschel K, Rüther W, Niemeier A.

Osteoarthritis Cartilage. 2016 Dec;24(12):2092-2099. doi: 10.1016/j.joca.2016.06.020. Epub 2016 Jul 5.


Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population.

Hawellek T, Hubert J, Hischke S, Vettorazzi E, Wegscheider K, Bertrand J, Pap T, Krause M, Püschel K, Rüther W, Niemeier A.

J Orthop Res. 2016 Nov;34(11):1984-1990. doi: 10.1002/jor.23227. Epub 2016 Apr 6.


Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.

Lin NY, Distler A, Beyer C, Philipi-Schöbinger A, Breda S, Dees C, Stock M, Tomcik M, Niemeier A, Dell'Accio F, Gelse K, Mattson MP, Schett G, Distler JH.

Ann Rheum Dis. 2016 Nov;75(11):2037-2044. doi: 10.1136/annrheumdis-2015-208420. Epub 2016 Feb 5.


Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness.

Jeschke A, Bonitz M, Simon M, Peters S, Baum W, Schett G, Ruether W, Niemeier A, Schinke T, Amling M.

PLoS One. 2015 Dec 2;10(12):e0144272. doi: 10.1371/journal.pone.0144272. eCollection 2015.


Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo.

Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J, Pitzalis C, Perretti M, Dell'Accio F.

Ann Rheum Dis. 2016 Jun;75(6):1228-35. doi: 10.1136/annrheumdis-2015-207316. Epub 2015 Aug 19.


The 2013 austrian-swiss-german traveling fellowship tour.

Renkawitz T, Niemeier A, von Knoch F, Biedermann R.

Orthop Rev (Pavia). 2014 May 6;6(2):5469. doi: 10.4081/or.2014.5469. eCollection 2014 Apr 22. No abstract available.


Signature of circulating microRNAs in osteoarthritis.

Beyer C, Zampetaki A, Lin NY, Kleyer A, Perricone C, Iagnocco A, Distler A, Langley SR, Gelse K, Sesselmann S, Lorenzini R, Niemeier A, Swoboda B, Distler JH, Santer P, Egger G, Willeit J, Mayr M, Schett G, Kiechl S.

Ann Rheum Dis. 2015 Mar;74(3):e18. doi: 10.1136/annrheumdis-2013-204698. Epub 2014 Feb 10.


Massive accumulation of osteoclastic giant cells in rapid destructive hip disease.

Seitz S, Zustin J, Amling M, Rüther W, Niemeier A.

J Orthop Res. 2014 May;32(5):702-8. doi: 10.1002/jor.22573. Epub 2014 Jan 31.


Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity.

Bartelt A, Beil FT, Müller B, Koehne T, Yorgan TA, Heine M, Yilmaz T, Rüther W, Heeren J, Schinke T, Niemeier A.

Bone. 2014 May;62:90-8. doi: 10.1016/j.bone.2014.01.001. Epub 2014 Jan 16.


[Resurfacing of the humeral head : sensible indications].

Fink B, Niemeier A, Rüther W.

Orthopade. 2013 Jul;42(7):490-4. doi: 10.1007/s00132-012-2019-3. German.


Structural brain changes in chronic pain reflect probably neither damage nor atrophy.

Rodriguez-Raecke R, Niemeier A, Ihle K, Ruether W, May A.

PLoS One. 2013;8(2):e54475. doi: 10.1371/journal.pone.0054475. Epub 2013 Feb 6.


European lipoprotein club: report of the 35th ELC annual conference (Tutzing, 10th-13th September 2012).

Costet P, Ehrenborg E, Fisher R, Fielding B, Groen A, Kardassis D, Malle E, Mulder M, Niemeier A, Norata GD, Hansen AT, Eckardstein Av.

Atherosclerosis. 2013 Feb;226(2):510-6. doi: 10.1016/j.atherosclerosis.2012.11.030. Epub 2012 Dec 5. No abstract available.


Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning.

Bartelt A, Weigelt C, Cherradi ML, Niemeier A, Tödter K, Heeren J, Scheja L.

Biochim Biophys Acta. 2013 May;1831(5):934-42. doi: 10.1016/j.bbalip.2012.11.011. Epub 2012 Dec 8.


Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.

Dieckmann M, Beil FT, Mueller B, Bartelt A, Marshall RP, Koehne T, Amling M, Ruether W, Cooper JA, Humphries SE, Herz J, Niemeier A.

J Bone Miner Res. 2013 Feb;28(2):236-45. doi: 10.1002/jbmr.1757.


Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.

Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Huebner AK, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T.

J Neuroendocrinol. 2013 Jan;25(1):14-22. doi: 10.1111/j.1365-2826.2012.02366.x.


Serum levels of fetal antigen 1 in extreme nutritional States.

Andries A, Niemeier A, Støving RK, Abdallah BM, Wolf AM, Hørder K, Kassem M.

ISRN Endocrinol. 2012;2012:592648. doi: 10.5402/2012/592648. Epub 2012 Jul 15.


Osteochondritis dissecans of the tarsal navicular bone: a case report.

Beil FT, Bruns J, Habermann CR, Rüther W, Niemeier A.

J Am Podiatr Med Assoc. 2012 Jul-Aug;102(4):338-42.


European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011.

Bernini F, Costet P, Ehrenborg E, Fisher R, Fielding B, Freeman D, Groen A, Malle E, Mulder M, Niemeier A, Hansen AT, von Eckardstein A.

Atherosclerosis. 2012 Mar;221(1):287-93. doi: 10.1016/j.atherosclerosis.2011.12.002. Epub 2011 Dec 11. No abstract available.


The role of apolipoprotein E in bone metabolism.

Niemeier A, Schinke T, Heeren J, Amling M.

Bone. 2012 Feb;50(2):518-24. doi: 10.1016/j.bone.2011.07.015. Epub 2011 Jul 23. Review.


[Shoulder arthroplasty for primary synovial diseases].

Niemeier A, Rüther W.

Z Rheumatol. 2011 Jul;70(5):380, 382-7. doi: 10.1007/s00393-011-0769-7. German.


Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010.

Bernini F, Fisher R, Freeman D, Groen A, Kalopissis A, Malle E, Mulder M, Niemeier A, Parini P, Hansen AT, von Eckardstein A.

Atherosclerosis. 2011 Mar;215(1):249-55. doi: 10.1016/j.atherosclerosis.2010.12.002. Epub 2010 Dec 10. No abstract available.


Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo.

Prawitt J, Beil FT, Marshall RP, Bartelt A, Ruether W, Heeren J, Amling M, Staels B, Niemeier A.

Bone. 2011 Feb;48(2):339-46. doi: 10.1016/j.bone.2010.08.018. Epub 2010 Sep 15.


Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity.

Bartelt A, Beil FT, Schinke T, Roeser K, Ruether W, Heeren J, Niemeier A.

Bone. 2010 Oct;47(4):736-45. doi: 10.1016/j.bone.2010.07.002. Epub 2010 Jul 12.


Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo.

Choi HY, Dieckmann M, Herz J, Niemeier A.

PLoS One. 2009 Nov 20;4(11):e7930. doi: 10.1371/journal.pone.0007930.


Brain gray matter decrease in chronic pain is the consequence and not the cause of pain.

Rodriguez-Raecke R, Niemeier A, Ihle K, Ruether W, May A.

J Neurosci. 2009 Nov 4;29(44):13746-50. doi: 10.1523/JNEUROSCI.3687-09.2009.


Early microvascular complications of prediabetes in mice with impaired glucose tolerance and dyslipidemia.

Schaefer C, Biermann T, Schroeder M, Fuhrhop I, Niemeier A, Rüther W, Algenstaedt P, Hansen-Algenstaedt N.

Acta Diabetol. 2010 Dec;47 Suppl 1:19-27. doi: 10.1007/s00592-009-0114-7. Epub 2009 Apr 15.


Uptake of postprandial lipoproteins into bone in vivo: impact on osteoblast function.

Niemeier A, Niedzielska D, Secer R, Schilling A, Merkel M, Enrich C, Rensen PC, Heeren J.

Bone. 2008 Aug;43(2):230-7. doi: 10.1016/j.bone.2008.03.022. Epub 2008 Apr 10.


Atherogenic diet leads to posttranslational down-regulation of murine hepatocyte SR-BI expression.

Niemeier A, Kovacs WJ, Strobl W, Stangl H.

Atherosclerosis. 2009 Jan;202(1):169-75. doi: 10.1016/j.atherosclerosis.2008.04.018. Epub 2008 Apr 24.


Characterization of lipid metabolism in insulin-sensitive adipocytes differentiated from immortalized human mesenchymal stem cells.

Prawitt J, Niemeier A, Kassem M, Beisiegel U, Heeren J.

Exp Cell Res. 2008 Feb 15;314(4):814-24. Epub 2007 Nov 22.


Knockdown of hepatic ABCA1 by RNA interference decreases plasma HDL cholesterol levels and influences postprandial lipemia in mice.

Ragozin S, Niemeier A, Laatsch A, Loeffler B, Merkel M, Beisiegel U, Heeren J.

Arterioscler Thromb Vasc Biol. 2005 Jul;25(7):1433-8. Epub 2005 Apr 21.


Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone.

Niemeier A, Kassem M, Toedter K, Wendt D, Ruether W, Beisiegel U, Heeren J.

J Bone Miner Res. 2005 Feb;20(2):283-93. Epub 2004 Nov 1.


Increased bone formation in mice lacking apolipoprotein E.

Schilling AF, Schinke T, Münch C, Gebauer M, Niemeier A, Priemel M, Streichert T, Rueger JM, Amling M.

J Bone Miner Res. 2005 Feb;20(2):274-82. Epub 2004 Nov 1.


Endothelial-derived lipoprotein lipase is bound to postprandial triglyceride-rich lipoproteins and mediates their hepatic clearance in vivo.

Heeren J, Niemeier A, Merkel M, Beisiegel U.

J Mol Med (Berl). 2002 Sep;80(9):576-84. Epub 2002 Jun 18.


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