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Items: 1 to 50 of 77

1.

Ensuring Sustainability of Needed Antibiotics: Aiming for the DART Board.

Spellberg B, Nielsen TB, Gilbert DN, Shorr AF, Brass EP.

Ann Intern Med. 2019 Oct 8. doi: 10.7326/M19-1893. [Epub ahead of print] No abstract available.

PMID:
31590184
2.

Natural history of Acinetobacter baumannii infection in mice.

Luna BM, Yan J, Reyna Z, Moon E, Nielsen TB, Reza H, Lu P, Bonomo R, Louie A, Drusano G, Bulitta J, She R, Spellberg B.

PLoS One. 2019 Jul 18;14(7):e0219824. doi: 10.1371/journal.pone.0219824. eCollection 2019.

3.

Sustainable Discovery and Development of Antibiotics - Is a Nonprofit Approach the Future?

Nielsen TB, Brass EP, Gilbert DN, Bartlett JG, Spellberg B.

N Engl J Med. 2019 Aug 8;381(6):503-505. doi: 10.1056/NEJMp1905589. Epub 2019 Jun 19. No abstract available.

4.

Vaccines targeting Staphylococcus aureus skin and bloodstream infections require different composition.

Luna BM, Nielsen TB, Cheng B, Pantapalangkoor P, Yan J, Boyle-Vavra S, Bruhn KW, Montgomery C, Spellberg B, Daum R.

PLoS One. 2019 Jun 10;14(6):e0217439. doi: 10.1371/journal.pone.0217439. eCollection 2019.

5.

Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria.

Luna BM, Ershova K, Yan J, Ulhaq A, Nielsen TB, Hsieh S, Pantapalangkoor P, Vanscoy B, Ambrose P, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar EP, Spellberg B.

J Antimicrob Chemother. 2019 Sep 1;74(9):2631-2639. doi: 10.1093/jac/dkz225.

6.

Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM.

Nielsen TB, Thomsen RP, Mortensen MR, Kjems J, Nielsen PF, Nielsen TE, Kodal ALB, Cló E, Gothelf KV.

Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9068-9072. doi: 10.1002/anie.201903134. Epub 2019 May 28.

PMID:
30995340
7.

Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation.

Choi YJ, Kim S, Choi Y, Nielsen TB, Yan J, Lu A, Ruan J, Lee HR, Wu H, Spellberg B, Jung JU.

Nat Immunol. 2019 May;20(5):664. doi: 10.1038/s41590-019-0361-x.

PMID:
30846880
8.

Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect.

Ambrose PG, VanScoy BD, Luna BM, Yan J, Ulhaq A, Nielsen TB, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar E, Spellberg B.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00112-19. doi: 10.1128/AAC.00112-19. Print 2019 May.

9.

SERPINB1-mediated checkpoint of inflammatory caspase activation.

Choi YJ, Kim S, Choi Y, Nielsen TB, Yan J, Lu A, Ruan J, Lee HR, Wu H, Spellberg B, Jung JU.

Nat Immunol. 2019 Mar;20(3):276-287. doi: 10.1038/s41590-018-0303-z. Epub 2019 Jan 28. Erratum in: Nat Immunol. 2019 Mar 7;:.

10.

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia.

Nielsen TB, Yan J, Luna B, Spellberg B.

J Vis Exp. 2018 Jun 28;(136). doi: 10.3791/57672.

11.

Publisher Correction: Development of a genetically encodable FRET system using fluorescent RNA aptamers.

Jepsen MDE, Sparvath SM, Nielsen TB, Langvad AH, Grossi G, Gothelf KV, Andersen ES.

Nat Commun. 2018 Feb 9;9(1):669. doi: 10.1038/s41467-018-03075-5.

12.

Development of a genetically encodable FRET system using fluorescent RNA aptamers.

Jepsen MDE, Sparvath SM, Nielsen TB, Langvad AH, Grossi G, Gothelf KV, Andersen ES.

Nat Commun. 2018 Jan 2;9(1):18. doi: 10.1038/s41467-017-02435-x. Erratum in: Nat Commun. 2018 Feb 9;9(1):669.

13.

Monoclonal Antibody Protects Against Acinetobacter baumannii Infection by Enhancing Bacterial Clearance and Evading Sepsis.

Nielsen TB, Pantapalangkoor P, Luna BM, Bruhn KW, Yan J, Dekitani K, Hsieh S, Yeshoua B, Pascual B, Vinogradov E, Hujer KM, Domitrovic TN, Bonomo RA, Russo TA, Lesczcyniecka M, Schneider T, Spellberg B.

J Infect Dis. 2017 Aug 15;216(4):489-501. doi: 10.1093/infdis/jix315.

14.

Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE.

Nielsen TB, Pantapalangkoor P, Yan J, Luna BM, Dekitani K, Bruhn K, Tan B, Junus J, Bonomo RA, Schmidt AM, Everson M, Duncanson F, Doherty TM, Lin L, Spellberg B.

MBio. 2017 Aug 22;8(4). pii: e00818-17. doi: 10.1128/mBio.00818-17.

15.

Heterogeneous FDG-guided dose-escalation for locally advanced NSCLC (the NARLAL2 trial): Design and early dosimetric results of a randomized, multi-centre phase-III study.

Møller DS, Nielsen TB, Brink C, Hoffmann L, Lutz CM, Drøgemüller Lund M, Hansen O, Schytte T, Khalil AA, Knap MM, Nyhus CH, Ottosson W, Sibolt P, Borissova S, Josipovic M, Persson G, Appelt AL.

Radiother Oncol. 2017 Aug;124(2):311-317. doi: 10.1016/j.radonc.2017.06.022. Epub 2017 Jul 5.

16.

Selectable Markers for Use in Genetic Manipulation of Extensively Drug-Resistant (XDR) Acinetobacter baumannii HUMC1.

Luna BM, Ulhaq A, Yan J, Pantapalangkoor P, Nielsen TB, Davies BW, Actis LA, Spellberg B.

mSphere. 2017 Apr 26;2(2). pii: e00140-17. doi: 10.1128/mSphere.00140-17. eCollection 2017 Mar-Apr.

17.

Evaluation of serotypes 5 and 8 capsular polysaccharides in protection against Staphylococcus aureus in murine models of infection.

Cheng BL, Nielsen TB, Pantapalangkoor P, Zhao F, Lee JC, Montgomery CP, Luna B, Spellberg B, Daum RS.

Hum Vaccin Immunother. 2017 Jul 3;13(7):1609-1614. doi: 10.1080/21645515.2017.1304334. Epub 2017 Apr 19.

18.

Microvesicles Correlated with Components of Metabolic Syndrome in Men with Type 2 Diabetes Mellitus and Lowered Testosterone Levels But Were Unaltered by Testosterone Therapy.

Botha J, Velling Magnussen L, Nielsen MH, Nielsen TB, Højlund K, Andersen MS, Handberg A.

J Diabetes Res. 2017;2017:4257875. doi: 10.1155/2017/4257875. Epub 2017 Jan 12.

19.

Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges.

Wong D, Nielsen TB, Bonomo RA, Pantapalangkoor P, Luna B, Spellberg B.

Clin Microbiol Rev. 2017 Jan;30(1):409-447. Review.

20.

Ly6G-mediated depletion of neutrophils is dependent on macrophages.

Bruhn KW, Dekitani K, Nielsen TB, Pantapalangkoor P, Spellberg B.

Results Immunol. 2015 Dec 21;6:5-7. doi: 10.1016/j.rinim.2015.12.001. eCollection 2016.

21.

In vitro Incubation of Platelets with oxLDL Does Not Induce Microvesicle Release When Measured by Sensitive Flow Cytometry.

Nielsen TB, Nielsen MH, Handberg A.

Front Cardiovasc Med. 2015 Nov 30;2:37. doi: 10.3389/fcvm.2015.00037. eCollection 2015.

22.

Impact of 4D image quality on the accuracy of target definition.

Nielsen TB, Hansen CR, Westberg J, Hansen O, Brink C.

Australas Phys Eng Sci Med. 2016 Mar;39(1):103-12. doi: 10.1007/s13246-015-0400-3. Epub 2015 Nov 17.

PMID:
26577711
23.

Cryopreservation of virulent Acinetobacter baumannii to reduce variability of in vivo studies.

Nielsen TB, Bruhn KW, Pantapalangkoor P, Junus JL, Spellberg B.

BMC Microbiol. 2015 Nov 2;15:252. doi: 10.1186/s12866-015-0580-8.

24.

Pattern of loco-regional failure after definitive radiotherapy for non-small cell lung cancer.

Schytte T, Nielsen TB, Brink C, Hansen O.

Acta Oncol. 2014 Mar;53(3):336-41. doi: 10.3109/0284186X.2013.868035. Epub 2013 Dec 26.

PMID:
24369735
25.

Comparison of three immobilisation systems for radiation therapy in head and neck cancer.

Hansen CR, Christiansen RL, Nielsen TB, Bertelsen AS, Johansen J, Brink C.

Acta Oncol. 2014 Mar;53(3):423-7. doi: 10.3109/0284186X.2013.813966. Epub 2013 Sep 24. No abstract available.

PMID:
24063295
26.

Four-dimensional dose evaluation of inhomogeneous dose distributions planned for non-small cell lung cancer patients with lymph node involvement.

Nielsen TB, Hansen O, Schytte T, Brink C.

Acta Oncol. 2014 May;53(5):707-12. doi: 10.3109/0284186X.2013.835492. Epub 2013 Sep 12. No abstract available.

PMID:
24028531
27.

Inhomogeneous dose escalation increases expected local control for NSCLC patients with lymph node involvement without increased mean lung dose.

Nielsen TB, Hansen O, Schytte T, Brink C.

Acta Oncol. 2014 Jan;53(1):119-25. doi: 10.3109/0284186X.2013.790560. Epub 2013 Apr 29.

PMID:
23627917
28.

A dual centre study of setup accuracy for thoracic patients based on cone-beam CT data.

Nielsen TB, Hansen VN, Westberg J, Hansen O, Brink C.

Radiother Oncol. 2012 Feb;102(2):281-6. doi: 10.1016/j.radonc.2011.11.012. Epub 2011 Dec 21.

PMID:
22196681
29.

Influence of dose calculation algorithms on the predicted dose distribution and NTCP values for NSCLC patients.

Nielsen TB, Wieslander E, Fogliata A, Nielsen M, Hansen O, Brink C.

Med Phys. 2011 May;38(5):2412-8.

PMID:
21776775
30.

Thermodynamic investigations of methyl tert-butyl ether and water mixtures.

Nielsen TB, Hvidt S, Keiding SR, Petersen C, Westh P, Keiding K.

Phys Chem Chem Phys. 2011 Jan 21;13(3):1182-8. doi: 10.1039/c0cp00494d. Epub 2010 Nov 12.

PMID:
21072404
31.

A giant outburst two years before the core-collapse of a massive star.

Pastorello A, Smartt SJ, Mattila S, Eldridge JJ, Young D, Itagaki K, Yamaoka H, Navasardyan H, Valenti S, Patat F, Agnoletto I, Augusteijn T, Benetti S, Cappellaro E, Boles T, Bonnet-Bidaud JM, Botticella MT, Bufano F, Cao C, Deng J, Dennefeld M, Elias-Rosa N, Harutyunyan A, Keenan FP, Iijima T, Lorenzi V, Mazzali PA, Meng X, Nakano S, Nielsen TB, Smoker JV, Stanishev V, Turatto M, Xu D, Zampieri L.

Nature. 2007 Jun 14;447(7146):829-32.

PMID:
17568740
32.

OAS1 splice site polymorphism controlling antiviral enzyme activity influences susceptibility to type 1 diabetes.

Field LL, Bonnevie-Nielsen V, Pociot F, Lu S, Nielsen TB, Beck-Nielsen H.

Diabetes. 2005 May;54(5):1588-91.

33.

Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.

Bonnevie-Nielsen V, Field LL, Lu S, Zheng DJ, Li M, Martensen PM, Nielsen TB, Beck-Nielsen H, Lau YL, Pociot F.

Am J Hum Genet. 2005 Apr;76(4):623-33. Epub 2005 Feb 24.

34.

[Islet transplantation in type 1 diabetes. Status and perspectives].

Jensen JE, Laursen SB, Nielsen TB, Yderstraede KB, Beck-Nielsen H.

Ugeskr Laeger. 2003 Dec 8;165(50):4859-61. Review. Danish. No abstract available.

PMID:
14716906
35.

Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.

Nielsen TB, Yderstraede KB, Schrøder HD, Holst JJ, Brusgaard K, Beck-Nielsen H.

Cell Transplant. 2003;12(1):13-25.

PMID:
12693660
36.

Isolation, transplantation, and functional studies of adult porcine islets of Langerhans.

Nielsen TB, Yderstraede KB, Beck-Nielsen H.

Comp Med. 2002 Apr;52(2):127-35.

PMID:
12022392
37.

Cyclopentyladenosine improves cell proliferation, wound healing, and hair growth.

Sun LL, Xu LL, Nielsen TB, Rhee P, Burris D.

J Surg Res. 1999 Nov;87(1):14-24.

PMID:
10527699
38.

Electric cautery lowers the contamination threshold for infection of laparotomies.

Soballe PW, Nimbkar NV, Hayward I, Nielsen TB, Drucker WR.

Am J Surg. 1998 Apr;175(4):263-6.

PMID:
9568648
39.

Transfection with aFGF cDNA improves wound healing.

Sun L, Xu L, Chang H, Henry FA, Miller RM, Harmon JM, Nielsen TB.

J Invest Dermatol. 1997 Mar;108(3):313-8.

40.

Cellular responses to surgical trauma, hemorrhage, and resuscitation with diaspirin cross-linked hemoglobin in rats.

Xu L, Sun L, Rollwagen FM, Li Y, Pacheco ND, Pikoulis E, Leppäniemi A, Soltero R, Burris D, Malcolm D, Nielsen TB.

J Trauma. 1997 Jan;42(1):32-41.

PMID:
9003255
41.

Systemic bacteraemia following haemorrhagic shock in mice: alleviation with oral Interleukin 6.

Rollwagen FM, Li YY, Pacheco ND, Nielsen TB.

Cytokine. 1996 Feb;8(2):121-9.

PMID:
8777269
42.

A new wound healing agent--sphingosylphosphorylcholine.

Sun L, Xu L, Henry FA, Spiegel S, Nielsen TB.

J Invest Dermatol. 1996 Feb;106(2):232-7.

43.

Multiple responses to administration of liposome-encapsulated hemoglobin (LEH): Effects on hematopoiesis and serum IL-6 levels.

Rollwagen FM, Gafney WC, Pacheco ND, Davis TA, Hickey TM, Nielsen TB, Rudolph AS.

Exp Hematol. 1996 Feb;24(3):429-36.

PMID:
8599972
44.

Biochemical properties of cloned lipases from the Pseudomonas family.

Svendsen A, Borch K, Barfoed M, Nielsen TB, Gormsen E, Patkar SA.

Biochim Biophys Acta. 1995 Oct 26;1259(1):9-17.

PMID:
7492621
45.

Spatially controlled adhesion, spreading, and differentiation of endothelial cells on self-assembled molecular monolayers.

Spargo BJ, Testoff MA, Nielsen TB, Stenger DA, Hickman JJ, Rudolph AS.

Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11070-4.

46.
47.

Retroviral transformation of cerebral microvascular endothelial cells: macrophage-like and microvascular endothelial cell properties.

Robinson DH, Warren MK, Liang LT, Oprandy JJ, Nielsen TB, Kang YH.

Blood. 1991 Jan 15;77(2):294-305.

PMID:
1985696
48.

Morphologic plasticity and periodicity: porcine cerebral microvascular cells in culture.

Robinson DH, Kang YH, Deschner SH, Nielsen TB.

In Vitro Cell Dev Biol. 1990 Feb;26(2):169-80.

PMID:
2312500
50.

Bradykinin and bradykinin antagonists effects on endothelial cell phosphoinositide metabolism; implications for septic shock.

Nielsen TB, Wood DK.

Prog Clin Biol Res. 1989;286:101-8. No abstract available.

PMID:
2538844

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