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Items: 1 to 50 of 72

1.

An invertebrate model for CNS drug discovery: Transcriptomic and functional analysis of a mammalian P-glycoprotein ortholog.

Al-Qadi S, Schiøtt M, Hansen SH, Nielsen PA, Badolo L.

Biochim Biophys Acta. 2015 Dec;1850(12):2439-51. doi: 10.1016/j.bbagen.2015.09.002. Epub 2015 Sep 10.

PMID:
26363463
2.

Characterization of a novel brain barrier ex vivo insect-based P-glycoprotein screening model.

Andersson O, Badisco L, Hansen AH, Hansen SH, Hellman K, Nielsen PA, Olsen LR, Verdonck R, Abbott NJ, Vanden Broeck J, Andersson G.

Pharmacol Res Perspect. 2014 Aug;2(4):e00050. doi: 10.1002/prp2.50. Epub 2014 Jun 9.

3.

Identification of a functional homolog of the mammalian CYP3A4 in locusts.

Olsen LR, Gabel-Jensen C, Nielsen PA, Hansen SH, Badolo L.

Drug Metab Dispos. 2014 Jul;42(7):1153-62. doi: 10.1124/dmd.114.057430. Epub 2014 Apr 28.

PMID:
24778367
4.

The grasshopper: a novel model for assessing vertebrate brain uptake.

Andersson O, Hansen SH, Hellman K, Olsen LR, Andersson G, Badolo L, Svenstrup N, Nielsen PA.

J Pharmacol Exp Ther. 2013 Aug;346(2):211-8. doi: 10.1124/jpet.113.205476. Epub 2013 May 13.

PMID:
23671124
5.

Models for predicting blood-brain barrier permeation.

Nielsen PA, Andersson O, Hansen SH, Simonsen KB, Andersson G.

Drug Discov Today. 2011 Jun;16(11-12):472-5. doi: 10.1016/j.drudis.2011.04.004. Epub 2011 Apr 12.

PMID:
21513815
6.

Moulds in floor dust - a particular problem in mechanically ventilated rooms? A study of adolescent schoolboys under the Danish moulds in buildings program.

Meyer HW, Suadicani P, Nielsen PA, Sigsgaard T, Gyntelberg F.

Scand J Work Environ Health. 2011 Jul;37(4):332-40. doi: 10.5271/sjweh.3135. Epub 2010 Nov 23.

7.

Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists.

Grimstrup M, Receveur JM, Rist Ø, Frimurer TM, Nielsen PA, Mathiesen JM, Högberg T.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1638-41. doi: 10.1016/j.bmcl.2010.01.092. Epub 2010 Jan 22.

PMID:
20137942
8.

Conversion of 4-cyanomethyl-pyrazole-3-carboxamides into CB1 antagonists with lowered propensity to pass the blood-brain-barrier.

Receveur JM, Murray A, Linget JM, Nørregaard PK, Cooper M, Bjurling E, Nielsen PA, Högberg T.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):453-7. doi: 10.1016/j.bmcl.2009.12.003. Epub 2009 Dec 4.

PMID:
20015647
9.

Exploring SAR features in diverse library of 4-cyanomethyl-pyrazole-3-carboxamides suitable for further elaborations as CB1 antagonists.

Cooper M, Receveur JM, Bjurling E, Nørregaard PK, Nielsen PA, Sköld N, Högberg T.

Bioorg Med Chem Lett. 2010 Jan 1;20(1):26-30. doi: 10.1016/j.bmcl.2009.11.047. Epub 2009 Nov 15.

PMID:
19954978
10.

Automated 2D peptide separation on a 1D nano-LC-MS system.

Taylor P, Nielsen PA, Trelle MB, Hørning OB, Andersen MB, Vorm O, Moran MF, Kislinger T.

J Proteome Res. 2009 Mar;8(3):1610-6. doi: 10.1021/pr800986c.

PMID:
19178303
11.
12.

Proteomic mapping of brain plasma membrane proteins.

Nielsen PA, Olsen JV, Podtelejnikov AV, Andersen JR, Mann M, Wisniewski JR.

Mol Cell Proteomics. 2005 Apr;4(4):402-8. Epub 2005 Jan 30.

13.

Warm or cold saline for volume preload before spinal anaesthesia for caesarean section?

Jørgensen HS, Bach LF, Helbo-Hansen HS, Nielsen PA.

Int J Obstet Anesth. 2000 Jan;9(1):20-5. Erratum in: Int J Obstet Anesth. 2000 Apr;9(2):148.

PMID:
15321106
14.

Experimental Peptide Identification Repository (EPIR): an integrated peptide-centric platform for validation and mining of tandem mass spectrometry data.

Kristensen DB, Brønd JC, Nielsen PA, Andersen JR, Sørensen OT, Jørgensen V, Budin K, Matthiesen J, Venø P, Jespersen HM, Ahrens CH, Schandorff S, Ruhoff PT, Wisniewski JR, Bennett KL, Podtelejnikov AV.

Mol Cell Proteomics. 2004 Oct;3(10):1023-38. Epub 2004 Jul 29.

15.

HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain.

Olsen JV, Andersen JR, Nielsen PA, Nielsen ML, Figeys D, Mann M, Wisniewski JR.

Mol Cell Proteomics. 2004 Jan;3(1):82-92. Epub 2003 Nov 10.

16.

Sequence and phylogenetic analyses of 4 TMS junctional proteins of animals: connexins, innexins, claudins and occludins.

Hua VB, Chang AB, Tchieu JH, Kumar NM, Nielsen PA, Saier MH Jr.

J Membr Biol. 2003 Jul 1;194(1):59-76.

PMID:
14502443
17.

Sensory evaluation of emissions from selected building products exposed to ozone.

Knudsen HN, Nielsen PA, Clausen PA, Wilkins CK, Wolkoff P.

Indoor Air. 2003 Sep;13(3):223-31.

PMID:
12950584
18.

Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues.

Söhl G, Nielsen PA, Eiberger J, Willecke K.

Cell Commun Adhes. 2003 Jan-Feb;10(1):27-36.

PMID:
12881038
19.

Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1).

Nielsen PA, Baruch A, Shestopalov VI, Giepmans BN, Dunia I, Benedetti EL, Kumar NM.

Mol Biol Cell. 2003 Jun;14(6):2470-81. Epub 2003 Mar 7.

20.

Determination of fungal spore release from wet building materials.

Kildesø J, Würtz H, Nielsen KF, Kruse P, Wilkins K, Thrane U, Gravesen S, Nielsen PA, Schneider T.

Indoor Air. 2003 Jun;13(2):148-55.

PMID:
12756008
22.

Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1.

Nielsen PA, Beahm DL, Giepmans BN, Baruch A, Hall JE, Kumar NM.

J Biol Chem. 2002 Oct 11;277(41):38272-83. Epub 2002 Aug 1.

23.

Characterization of the association of connexins and ZO-1 in the lens.

Nielsen PA, Baruch A, Giepmans BN, Kumar NM.

Cell Commun Adhes. 2001;8(4-6):213-7.

PMID:
12064591
24.

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.

Ho Y, Gruhler A, Heilbut A, Bader GD, Moore L, Adams SL, Millar A, Taylor P, Bennett K, Boutilier K, Yang L, Wolting C, Donaldson I, Schandorff S, Shewnarane J, Vo M, Taggart J, Goudreault M, Muskat B, Alfarano C, Dewar D, Lin Z, Michalickova K, Willems AR, Sassi H, Nielsen PA, Rasmussen KJ, Andersen JR, Johansen LE, Hansen LH, Jespersen H, Podtelejnikov A, Nielsen E, Crawford J, Poulsen V, Sørensen BD, Matthiesen J, Hendrickson RC, Gleeson F, Pawson T, Moran MF, Durocher D, Mann M, Hogue CW, Figeys D, Tyers M.

Nature. 2002 Jan 10;415(6868):180-3.

PMID:
11805837
25.
26.
27.

Defining a link between gap junction communication, proteolysis, and cataract formation.

Baruch A, Greenbaum D, Levy ET, Nielsen PA, Gilula NB, Kumar NM, Bogyo M.

J Biol Chem. 2001 Aug 3;276(31):28999-9006. Epub 2001 Jun 6.

28.

The effect of dextromethorphan, alone or in combination with ibuprofen, on postoperative pain after minor gynaecological surgery.

Ilkjaer S, Nielsen PA, Bach LF, Wernberg M, Dahl JB.

Acta Anaesthesiol Scand. 2000 Aug;44(7):873-7.

PMID:
10939702
29.
30.

Production of mycotoxins on artificially and naturally infested building materials.

Nielsen KF, Gravesen S, Nielsen PA, Andersen B, Thrane U, Frisvad JC.

Mycopathologia. 1999;145(1):43-56.

PMID:
10560628
31.

Microfungal contamination of damp buildings--examples of risk constructions and risk materials.

Gravesen S, Nielsen PA, Iversen R, Nielsen KF.

Environ Health Perspect. 1999 Jun;107 Suppl 3:505-8.

32.

MUC5B and MUC7 are differentially expressed in mucous and serous cells of submucosal glands in human bronchial airways.

Sharma P, Dudus L, Nielsen PA, Clausen H, Yankaskas JR, Hollingsworth MA, Engelhardt JF.

Am J Respir Cell Mol Biol. 1998 Jul;19(1):30-7.

PMID:
9651178
33.

A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family.

Amado M, Almeida R, Carneiro F, Levery SB, Holmes EH, Nomoto M, Hollingsworth MA, Hassan H, Schwientek T, Nielsen PA, Bennett EP, Clausen H.

J Biol Chem. 1998 May 22;273(21):12770-8.

34.

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.

Wandall HH, Hassan H, Mirgorodskaya E, Kristensen AK, Roepstorff P, Bennett EP, Nielsen PA, Hollingsworth MA, Burchell J, Taylor-Papadimitriou J, Clausen H.

J Biol Chem. 1997 Sep 19;272(38):23503-14.

35.

Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B.

Nielsen PA, Bennett EP, Wandall HH, Therkildsen MH, Hannibal J, Clausen H.

Glycobiology. 1997 Apr;7(3):413-9.

PMID:
9147051
36.

Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody.

Reis CA, David L, Nielsen PA, Clausen H, Mirgorodskaya K, Roepstorff P, Sobrinho-Simões M.

Int J Cancer. 1997 Feb 20;74(1):112-21.

37.

Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas.

Nielsen PA, Mandel U, Therkildsen MH, Ravn V, David L, Reis CA, Wandall HH, Dabelsteen E, Clausen H.

Cancer Res. 1997 Feb 15;57(4):634-40.

38.

Differential expression of human high-molecular-weight salivary mucin (MG1) and low-molecular-weight salivary mucin (MG2).

Nielsen PA, Mandel U, Therkildsen MH, Clausen H.

J Dent Res. 1996 Nov;75(11):1820-6.

PMID:
9003227
39.

PVC cling film in contact with cheese: health aspects related to global migration and specific migration of DEHA.

Petersen JH, Naamansen ET, Nielsen PA.

Food Addit Contam. 1995 Mar-Apr;12(2):245-53.

PMID:
7781821
40.

Microsomal metabolism of the food mutagen 2-amino-3,4,8-trimethyl-3H-imidazo[4,5-f]-quinoxaline to mutagenic metabolites.

Frandsen H, Nielsen PA, Grivas S, Larsen JC.

Mutagenesis. 1994 Jan;9(1):59-65.

PMID:
8208131
41.

Chemical carcinogens in the environment: risk assessment for the environment.

Nielsen PA.

Pharmacol Toxicol. 1993;72 Suppl 1:46-50. Review.

PMID:
8474989
42.

Mutagenic activity of nine N,N-disubstituted hydrazines in the Salmonella/mammalian microsome assay.

Nielsen PA, Lagersted A, Danielsen S, Jensen AA, Hart J, Larsen JC.

Mutat Res. 1992 Apr;278(4):215-26.

PMID:
1373858
43.

Ca(2+)-ATPase and Na(+)-K(+)-ATPase content in skeletal muscle from malignant hyperthermia patients.

Everts ME, Ording H, Hansen O, Nielsen PA.

Muscle Nerve. 1992 Feb;15(2):162-7.

PMID:
1312675
44.

Quality of care: discovering a modified practice theory.

Nielsen PA.

J Nurs Care Qual. 1992 Jan;6(2):63-76. No abstract available.

PMID:
1728332
45.
46.

Metabolic formation, synthesis and genotoxicity of the N-hydroxy derivative of the food mutagen 2-amino-1-methyl-6-phenylimidazo (4,5-b) pyridine (PhIP).

Frandsen H, Rasmussen ES, Nielsen PA, Farmer P, Dragsted L, Larsen JC.

Mutagenesis. 1991 Jan;6(1):93-8.

PMID:
1903830
47.

House dust mite allergy and anti-mite measures in the indoor environment.

Harving H, Hansen LG, Korsgaard J, Nielsen PA, Olsen OF, Rømer J, Svendsen UG, Osterballe O.

Allergy. 1991;46 Suppl 11:33-8. Review. No abstract available.

PMID:
1897699
48.

Carcinogenicity of mutagens from cooked meats.

Larsen JC, Dragsted LO, Frandsen H, Kristiansen E, Rasmussen ES, Nielsen PA, Knudsen I.

Prog Clin Biol Res. 1990;347:89-108. Review. No abstract available.

PMID:
2217404
49.

[Comparison of propofol and thiopentone in young and elderly patients].

Nielsen PA, Ahlburg P, Schnedler HO, Christensen JH.

Ugeskr Laeger. 1989 Aug 28;151(35):2204-6. Danish.

PMID:
2789447
50.

[Permanent central venous catheter in pediatric oncology].

Nielsen PA, Jøhncke H, Due E.

Ugeskr Laeger. 1989 Jun 5;151(23):1470-2. Danish.

PMID:
2734952

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