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Items: 1 to 50 of 232

1.

Dual HER2 blockade in the first-line treatment of metastatic breast cancer - A retrospective population-based observational study in Danish patients.

Christensen T, Berg T, Nielsen LB, Andersson M, Jensen MB, Knoop A.

Breast. 2020 Mar 13;51:34-39. doi: 10.1016/j.breast.2020.03.002. [Epub ahead of print]

2.

Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs.

Mirza AH, Kaur S, Nielsen LB, Størling J, Yarani R, Roursgaard M, Mathiesen ER, Damm P, Svare J, Mortensen HB, Pociot F.

Front Immunol. 2019 Oct 25;10:2543. doi: 10.3389/fimmu.2019.02543. eCollection 2019.

3.

The clinical course of common bile duct stone clearance with endoscopic retrograde cholangio-pancreaticography.

Nielsen LBJ, Shabanzadeh DM, Aaresøn A, Sørensen LT.

Scand J Gastroenterol. 2019 Sep;54(9):1166-1171. doi: 10.1080/00365521.2019.1663259. Epub 2019 Sep 17.

PMID:
31526285
4.

Influenza and associated co-infections in critically ill immunosuppressed patients.

Martin-Loeches I, Lemiale V, Geoghegan P, McMahon MA, Pickkers P, Soares M, Perner A, Meyhoff TS, Bukan RB, Rello J, Bauer PR, van de Louw A, Taccone FS, Salluh J, Hemelaar P, Schellongowski P, Rusinova K, Terzi N, Mehta S, Antonelli M, Kouatchet A, Klepstad P, Valkonen M, Landburg PP, Barratt-Due A, Bruneel F, Pène F, Metaxa V, Moreau AS, Souppart V, Burghi G, Girault C, Silva UVA, Montini L, Barbier F, Nielsen LB, Gaborit B, Mokart D, Chevret S, Azoulay E; Efraim investigators and the Nine-I study group.

Crit Care. 2019 May 2;23(1):152. doi: 10.1186/s13054-019-2425-6.

5.

Acute intramyocardial lipid accumulation in rats does not slow cardiac conduction per se.

Jensen CF, Bartels ED, Braunstein TH, Nielsen LB, Holstein-Rathlou NH, Axelsen LN, Nielsen MS.

Physiol Rep. 2019 Apr;7(7):e14049. doi: 10.14814/phy2.14049.

6.

High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs.

Bartels ED, Guo S, Kousholt BS, Larsen JR, Hasenkam JM, Burnett J Jr, Nielsen LB, Ashina M, Goetze JP.

Peptides. 2019 Feb;112:43-47. doi: 10.1016/j.peptides.2018.11.003. Epub 2018 Nov 30.

PMID:
30508635
7.

Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes.

Samandari N, Mirza AH, Kaur S, Hougaard P, Nielsen LB, Fredheim S, Mortensen HB, Pociot F.

Noncoding RNA. 2018 Nov 21;4(4). pii: E35. doi: 10.3390/ncrna4040035.

8.

Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate.

Yafasova A, Mandrup CM, Egelund J, Nyberg M, Stallknecht B, Hellsten Y, Nielsen LB, Christoffersen C.

J Appl Physiol (1985). 2019 Jan 1;126(1):214-220. doi: 10.1152/japplphysiol.00527.2018. Epub 2018 Nov 15.

9.

Differential Effects of Digoxin on Imiquimod-Induced Psoriasis-Like Skin Inflammation on the Ear and Back.

Madsen M, Pedersen TX, Nielsen LB, Johansen C, Hansen PR.

Ann Dermatol. 2018 Aug;30(4):485-488. doi: 10.5021/ad.2018.30.4.485. Epub 2018 Jun 28. No abstract available.

10.

Apolipoprotein M in patients with chronic kidney disease.

Sørensen IM, Bertelsen M, Freese E, Lindhard K, Ullum H, Feldt-Rasmussen B, Nielsen LB, Christoffersen C, Bro S.

Atherosclerosis. 2018 Aug;275:304-311. doi: 10.1016/j.atherosclerosis.2018.06.815. Epub 2018 Jun 15.

PMID:
29980057
11.

Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs.

Al-Mashhadi AL, Poulsen CB, von Wachenfeldt K, Robertson AK, Bentzon JF, Nielsen LB, Thygesen J, Tolbod LP, Larsen JR, Moestrup SK, Frendéus B, Mortensen B, Drouet L, Al-Mashhadi RH, Falk E.

J Diabetes Res. 2018 Feb 25;2018:6823193. doi: 10.1155/2018/6823193. eCollection 2018.

12.

Personlig medicin vil involvere alle specialer, og det handler om andet end genomet.

Ullum H, Hersom C, Wewer U, Skøtt O, Nielsen LB, Rasmussen LH.

Ugeskr Laeger. 2018 Mar 19;180(12). pii: V69884. Danish. No abstract available.

PMID:
29559072
13.

Imiquimod-Induced Psoriasis-Like Skin Lesions Do Not Accelerate Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice.

Madsen M, Hansen PR, Nielsen LB, Cardoso RM, van Eck M, Pedersen TX.

Am J Pathol. 2018 Jun;188(6):1486-1496. doi: 10.1016/j.ajpath.2018.02.005. Epub 2018 Mar 12.

14.

Exercise and weight loss effects on cardiovascular risk factors in overweight men.

Rosenkilde M, Rygaard L, Nordby P, Nielsen LB, Stallknecht B.

J Appl Physiol (1985). 2018 Sep 1;125(3):901-908. doi: 10.1152/japplphysiol.01092.2017. Epub 2018 Mar 15.

15.

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity.

Christoffersen C, Federspiel CK, Borup A, Christensen PM, Madsen AN, Heine M, Nielsen CH, Kjaer A, Holst B, Heeren J, Nielsen LB.

Cell Rep. 2018 Jan 2;22(1):175-188. doi: 10.1016/j.celrep.2017.12.029.

16.

Concordance in BRAF V600E status over time in malignant melanoma and corresponding metastases.

Nielsen LB, Dabrosin N, Sloth K, Bønnelykke-Behrndtz ML, Steiniche T, Lade-Keller J.

Histopathology. 2018 Apr;72(5):814-825. doi: 10.1111/his.13431. Epub 2018 Feb 6.

PMID:
29119584
17.

Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes.

Christensen PM, Bosteen MH, Hajny S, Nielsen LB, Christoffersen C.

Sci Rep. 2017 Nov 8;7(1):14983. doi: 10.1038/s41598-017-15043-y.

18.

Acute hypoxemic respiratory failure in immunocompromised patients: the Efraim multinational prospective cohort study.

Azoulay E, Pickkers P, Soares M, Perner A, Rello J, Bauer PR, van de Louw A, Hemelaar P, Lemiale V, Taccone FS, Martin Loeches I, Meyhoff TS, Salluh J, Schellongowski P, Rusinova K, Terzi N, Mehta S, Antonelli M, Kouatchet A, Barratt-Due A, Valkonen M, Landburg PP, Bruneel F, Bukan RB, Pène F, Metaxa V, Moreau AS, Souppart V, Burghi G, Girault C, Silva UVA, Montini L, Barbier F, Nielsen LB, Gaborit B, Mokart D, Chevret S; Efraim investigators and the Nine-I study group.

Intensive Care Med. 2017 Dec;43(12):1808-1819. doi: 10.1007/s00134-017-4947-1. Epub 2017 Sep 25.

PMID:
28948369
19.

Effects of apolipoprotein M in uremic atherosclerosis.

Bosteen MH, Madsen Svarrer EM, Bisgaard LS, Martinussen T, Madsen M, Nielsen LB, Christoffersen C, Pedersen TX.

Atherosclerosis. 2017 Oct;265:93-101. doi: 10.1016/j.atherosclerosis.2017.08.005. Epub 2017 Aug 18.

PMID:
28866363
20.

Uremia does not affect neointima formation in mice.

Aarup A, Nielsen CH, Bisgaard LS, Bot I, El-Ali HH, Kjaer A, Nielsen LB, Pedersen TX.

Sci Rep. 2017 Jul 26;7(1):6496. doi: 10.1038/s41598-017-06816-6.

21.

The Bipolar Illness Onset study: research protocol for the BIO cohort study.

Kessing LV, Munkholm K, Faurholt-Jepsen M, Miskowiak KW, Nielsen LB, Frikke-Schmidt R, Ekstrøm C, Winther O, Pedersen BK, Poulsen HE, McIntyre RS, Kapczinski F, Gattaz WF, Bardram J, Frost M, Mayora O, Knudsen GM, Phillips M, Vinberg M.

BMJ Open. 2017 Jun 23;7(6):e015462. doi: 10.1136/bmjopen-2016-015462.

22.

Protocol for a randomised controlled trial of the effect of dapagliflozin, metformin and exercise on glycaemic variability, body composition and cardiovascular risk in prediabetes (the PRE-D Trial).

Færch K, Amadid H, Nielsen LB, Ried-Larsen M, Karstoft K, Persson F, Jørgensen ME.

BMJ Open. 2017 Jun 6;7(5):e013802. doi: 10.1136/bmjopen-2016-013802.

23.

Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels.

Reimann MJ, Møller JE, Häggström J, Martinussen T, Zatrazemi SSC, Svanholm L, Nielsen LBM, Pedersen HD, Olsen LH.

J Vet Intern Med. 2017 Jul;31(4):1008-1016. doi: 10.1111/jvim.14759. Epub 2017 Jun 1.

24.

Laparoscopy in major abdominal emergency surgery seems to be a safe procedure.

Nielsen LBJ, Tengberg LT, Bay-Nielsen M.

Dan Med J. 2017 May;64(5). pii: A5370.

PMID:
28552093
25.

ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis.

Christoffersen C, Bartels ED, Aarup A, Nielsen LB, Pedersen TX.

Eur J Pharmacol. 2017 Dec 5;816:154-160. doi: 10.1016/j.ejphar.2017.03.053. Epub 2017 Mar 25. Review.

PMID:
28351665
26.

Uremia modulates the phenotype of aortic smooth muscle cells.

Madsen M, Aarup A, Albinsson S, Hartvigsen K, Sørensen CM, Turczynska K, Nielsen LB, Pedersen TX.

Atherosclerosis. 2017 Feb;257:64-70. doi: 10.1016/j.atherosclerosis.2016.12.022. Epub 2016 Dec 23.

PMID:
28107707
27.

HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver.

Ding BS, Liu CH, Sun Y, Chen Y, Swendeman SL, Jung B, Chavez D, Cao Z, Christoffersen C, Nielsen LB, Schwab SR, Rafii S, Hla T.

JCI Insight. 2016 Dec 22;1(21):e87058. doi: 10.1172/jci.insight.87058.

28.

Liraglutide Reduces Both Atherosclerosis and Kidney Inflammation in Moderately Uremic LDLr-/- Mice.

Bisgaard LS, Bosteen MH, Fink LN, Sørensen CM, Rosendahl A, Mogensen CK, Rasmussen SE, Rolin B, Nielsen LB, Pedersen TX.

PLoS One. 2016 Dec 16;11(12):e0168396. doi: 10.1371/journal.pone.0168396. eCollection 2016.

29.

Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus.

Samandari N, Mirza AH, Nielsen LB, Kaur S, Hougaard P, Fredheim S, Mortensen HB, Pociot F.

Diabetologia. 2017 Feb;60(2):354-363. doi: 10.1007/s00125-016-4156-4. Epub 2016 Nov 19.

PMID:
27866223
30.

Complications after emergency laparotomy beyond the immediate postoperative period - a retrospective, observational cohort study of 1139 patients.

Tengberg LT, Cihoric M, Foss NB, Bay-Nielsen M, Gögenur I, Henriksen R, Jensen TK, Tolstrup MB, Nielsen LB.

Anaesthesia. 2017 Mar;72(3):309-316. doi: 10.1111/anae.13721. Epub 2016 Nov 3.

31.

Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression - implications for atherosclerosis research.

Bisgaard LS, Mogensen CK, Rosendahl A, Cucak H, Nielsen LB, Rasmussen SE, Pedersen TX.

Sci Rep. 2016 Oct 13;6:35234. doi: 10.1038/srep35234.

32.

Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis.

Aarup A, Pedersen TX, Junker N, Christoffersen C, Bartels ED, Madsen M, Nielsen CH, Nielsen LB.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1782-90. doi: 10.1161/ATVBAHA.116.307830. Epub 2016 Jul 21.

PMID:
27444197
33.

Effects of the genome on immune regulation in type 1 diabetes.

Pociot F, Kaur S, Nielsen LB.

Pediatr Diabetes. 2016 Jul;17 Suppl 22:37-42. doi: 10.1111/pedi.12336.

PMID:
27411435
34.

Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice.

Madsen M, Hansen PR, Nielsen LB, Hartvigsen K, Pedersen AE, Christensen JP, Aarup A, Pedersen TX.

BMC Dermatol. 2016 Jul 11;16(1):9. doi: 10.1186/s12895-016-0046-1.

35.

Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions.

Poulsen CB, Al-Mashhadi AL, von Wachenfeldt K, Bentzon JF, Nielsen LB, Al-Mashhadi RH, Thygesen J, Tolbod L, Larsen JR, Frøkiær J, Tawakol A, Vucic E, Fredrickson J, Baruch A, Frendéus B, Robertson AK, Moestrup SK, Drouet L, Falk E.

Int J Cardiol. 2016 Jul 15;215:506-15. doi: 10.1016/j.ijcard.2016.03.222. Epub 2016 Apr 2.

PMID:
27135822
36.

Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years.

Sandahl K, Nielsen LB, Svensson J, Johannesen J, Pociot F, Mortensen HB, Hougaard P, Broe R, Rasmussen ML, Grauslund J, Peto T, Olsen BS.

Diabet Med. 2017 Mar;34(3):380-386. doi: 10.1111/dme.13124. Epub 2016 Apr 21.

PMID:
27027777
37.

Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1.

Christensen PM, Liu CH, Swendeman SL, Obinata H, Qvortrup K, Nielsen LB, Hla T, Di Lorenzo A, Christoffersen C.

FASEB J. 2016 Jun;30(6):2351-9. doi: 10.1096/fj.201500064. Epub 2016 Mar 8.

38.

Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.

Brorsson CA, Nielsen LB, Andersen ML, Kaur S, Bergholdt R, Hansen L, Mortensen HB, Pociot F, Størling J; Hvidoere Study Group On Childhood Diabetes.

J Diabetes Res. 2016;2016:9570424. doi: 10.1155/2016/9570424. Epub 2016 Jan 20.

39.

Plasma ADAMTS-13 protein is not associated with portal hypertension or hemodynamic changes in patients with cirrhosis.

Wiese S, Timm A, Nielsen LB, Goetze JP, Bendtsen F, Møller S.

Dig Liver Dis. 2016 Apr;48(4):404-8. doi: 10.1016/j.dld.2015.12.003. Epub 2015 Dec 17.

PMID:
26775093
40.

Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43.

Morel S, Christoffersen C, Axelsen LN, Montecucco F, Rochemont V, Frias MA, Mach F, James RW, Naus CC, Chanson M, Lampe PD, Nielsen MS, Nielsen LB, Kwak BR.

Cardiovasc Res. 2016 Mar 1;109(3):385-96. doi: 10.1093/cvr/cvw004. Epub 2016 Jan 13.

41.

A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.

Fukaya M, Brorsson CA, Meyerovich K, Catrysse L, Delaroche D, Vanzela EC, Ortis F, Beyaert R, Nielsen LB, Andersen ML, Mortensen HB, Pociot F, van Loo G, Størling J, Cardozo AK.

Mol Endocrinol. 2016 Jan;30(1):48-61. doi: 10.1210/me.2015-1176. Epub 2015 Dec 10.

42.

[Amyloidosis presenting as melaena].

Jessen EM, Nielsen LB, Bønnelycke MK, Nordholm-Carstensen A.

Ugeskr Laeger. 2015 Nov 30;177(49):V06150544. Danish.

PMID:
26651555
43.

Urinary apolipoprotein M as a biomarker of acute kidney injury in children undergoing heart surgery.

Svarrer EM, Andersen HØ, Helvind M, Slagman MC, Navis G, Dullaart RP, Dahlbäck B, Nielsen LB.

Biomark Med. 2016;10(1):81-93. doi: 10.2217/bmm.15.105. Epub 2015 Dec 7.

44.

Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.

Bartels ED, Christoffersen C, Lindholm MW, Nielsen LB.

Circ Res. 2015 Nov 6;117(11):933-42. doi: 10.1161/CIRCRESAHA.115.307182. Epub 2015 Sep 10.

PMID:
26358193
45.

Impaired Glucose Tolerance in Healthy Men Treated with St. John's Wort.

Stage TB, Damkier P, Christensen MM, Nielsen LB, Højlund K, Brøsen K.

Basic Clin Pharmacol Toxicol. 2016 Mar;118(3):219-24. doi: 10.1111/bcpt.12486. Epub 2015 Oct 8.

46.

Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987).

Thorsen SU, Sandahl K, Nielsen LB, Broe R, Rasmussen ML, Peto T, Grauslund J, Andersen ML, Mortensen HB, Pociot F, Olsen BS, Brorsson C.

Graefes Arch Clin Exp Ophthalmol. 2015 Nov;253(11):1959-65. doi: 10.1007/s00417-015-3118-8. Epub 2015 Aug 6.

PMID:
26245339
47.

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis.

Axelsen LN, Calloe K, Braunstein TH, Riemann M, Hofgaard JP, Liang B, Jensen CF, Olsen KB, Bartels ED, Baandrup U, Jespersen T, Nielsen LB, Holstein-Rathlou NH, Nielsen MS.

Cardiovasc Diabetol. 2015 Jul 14;14:87. doi: 10.1186/s12933-015-0246-8.

48.

Genetic analysis of ligation-induced neointima formation in an F2 intercross of C57BL/6 and FVB/N inbred mouse strains.

Östergren C, Shim J, Larsen JV, Nielsen LB, Bentzon JF.

PLoS One. 2015 Apr 13;10(4):e0121899. doi: 10.1371/journal.pone.0121899. eCollection 2015.

49.

Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA.

Bosteen MH, Dahlbäck B, Nielsen LB, Christoffersen C.

J Lipid Res. 2015 Mar;56(3):754-9. doi: 10.1194/jlr.D055947. Epub 2015 Jan 5.

50.

Apolipoprotein M in lipid metabolism and cardiometabolic diseases.

Borup A, Christensen PM, Nielsen LB, Christoffersen C.

Curr Opin Lipidol. 2015 Feb;26(1):48-55. doi: 10.1097/MOL.0000000000000142. Review.

PMID:
25551802

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