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Items: 1 to 50 of 181

1.

Identification of the decumbenone biosynthetic gene cluster in Penicillium decumbens and the importance for production of calbistrin.

Grijseels S, Pohl C, Nielsen JC, Wasil Z, Nygård Y, Nielsen J, Frisvad JC, Nielsen KF, Workman M, Larsen TO, Driessen AJM, Frandsen RJN.

Fungal Biol Biotechnol. 2018 Dec 19;5:18. doi: 10.1186/s40694-018-0063-4. eCollection 2018.

2.

Uncovering secondary metabolite evolution and biosynthesis using gene cluster networks and genetic dereplication.

Theobald S, Vesth TC, Rendsvig JK, Nielsen KF, Riley R, de Abreu LM, Salamov A, Frisvad JC, Larsen TO, Andersen MR, Hoof JB.

Sci Rep. 2018 Dec 18;8(1):17957. doi: 10.1038/s41598-018-36561-3.

3.

Secondary metabolite profiles of small-spored Alternaria support the new phylogenetic organization of the genus.

Patriarca A, da Cruz Cabral L, Pavicich MA, Nielsen KF, Andersen B.

Int J Food Microbiol. 2019 Feb 16;291:135-143. doi: 10.1016/j.ijfoodmicro.2018.11.022. Epub 2018 Nov 23.

PMID:
30500690
4.

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri.

Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, Lyhne EK, Kogle ME, Strasser K, McDonnell E, Barry K, Clum A, Chen C, LaButti K, Haridas S, Nolan M, Sandor L, Kuo A, Lipzen A, Hainaut M, Drula E, Tsang A, Magnuson JK, Henrissat B, Wiebenga A, Simmons BA, Mäkelä MR, de Vries RP, Grigoriev IV, Mortensen UH, Baker SE, Andersen MR.

Nat Genet. 2018 Dec;50(12):1688-1695. doi: 10.1038/s41588-018-0246-1. Epub 2018 Oct 22.

PMID:
30349117
5.

Secondary metabolite production by cereal-associated penicillia during cultivation on cereal grains.

Hallas-Møller M, Nielsen KF, Frisvad JC.

Appl Microbiol Biotechnol. 2018 Oct;102(19):8477-8491. doi: 10.1007/s00253-018-9213-0. Epub 2018 Jul 11.

PMID:
29995241
6.

Phylogenetic distribution of roseobacticides in the Roseobacter group and their effect on microalgae.

Sonnenschein EC, Phippen CBW, Bentzon-Tilia M, Rasmussen SA, Nielsen KF, Gram L.

Environ Microbiol Rep. 2018 Jun;10(3):383-393. doi: 10.1111/1758-2229.12649. Epub 2018 Apr 23.

PMID:
29624899
7.

Cyclopiamines C and D: Epoxide Spiroindolinone Alkaloids from Penicillium sp. CML 3020.

Kildgaard S, de Medeiros LS, Phillips E, Gotfredsen CH, Frisvad JC, Nielsen KF, Abreu LM, Larsen TO.

J Nat Prod. 2018 Apr 27;81(4):785-790. doi: 10.1021/acs.jnatprod.7b00825. Epub 2018 Feb 28.

PMID:
29488766
8.

Plasma ceramide levels are altered in low and normal birth weight men in response to short-term high-fat overfeeding.

Ribel-Madsen A, Ribel-Madsen R, Nielsen KF, Brix S, Vaag AA, Brøns C.

Sci Rep. 2018 Feb 22;8(1):3452. doi: 10.1038/s41598-018-21419-5.

9.

Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals.

Theilmann MC, Goh YJ, Nielsen KF, Klaenhammer TR, Barrangou R, Abou Hachem M.

MBio. 2017 Nov 21;8(6). pii: e01421-17. doi: 10.1128/mBio.01421-17.

10.

Physiological characterization of secondary metabolite producing Penicillium cell factories.

Grijseels S, Nielsen JC, Nielsen J, Larsen TO, Frisvad JC, Nielsen KF, Frandsen RJN, Workman M.

Fungal Biol Biotechnol. 2017 Oct 17;4:8. doi: 10.1186/s40694-017-0036-z. eCollection 2017.

11.

Phaeobacter piscinae sp. nov., a species of the Roseobacter group and potential aquaculture probiont.

Sonnenschein EC, Phippen CBW, Nielsen KF, Mateiu RV, Melchiorsen J, Gram L, Overmann J, Freese HM.

Int J Syst Evol Microbiol. 2017 Nov;67(11):4559-4564. doi: 10.1099/ijsem.0.002331. Epub 2017 Oct 6.

PMID:
28984543
12.

Structure dependent antioxidant capacity of phlorotannins from Icelandic Fucus vesiculosus by UHPLC-DAD-ECD-QTOFMS.

Hermund DB, Plaza M, Turner C, Jónsdóttir R, Kristinsson HG, Jacobsen C, Nielsen KF.

Food Chem. 2018 Feb 1;240:904-909. doi: 10.1016/j.foodchem.2017.08.032. Epub 2017 Aug 10.

PMID:
28946360
13.

Prolonged hospitalization, primary refractory disease, performance status and age are prognostic factors for survival in patients with diffuse large B-cell lymphoma and transformed indolent lymphoma undergoing autologous stem cell transplantation.

Arboe B, Halgren Olsen M, Duun-Henriksen AK, Gørløv JS, Nielsen KF, Thomsen RH, Madsen C, Nielsen SR, Dalton SO, Brown PN.

Leuk Lymphoma. 2018 May;59(5):1153-1162. doi: 10.1080/10428194.2017.1369061. Epub 2017 Sep 4.

PMID:
28868963
14.

HPLC-HRMS Quantification of the Ichthyotoxin Karmitoxin from Karlodinium armiger.

Andersen AJC, de Medeiros LS, Binzer SB, Rasmussen SA, Hansen PJ, Nielsen KF, Jørgensen K, Larsen TO.

Mar Drugs. 2017 Aug 31;15(9). pii: E278. doi: 10.3390/md15090278.

15.

A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria.

Kildgaard S, Subko K, Phillips E, Goidts V, de la Cruz M, Díaz C, Gotfredsen CH, Andersen B, Frisvad JC, Nielsen KF, Larsen TO.

Mar Drugs. 2017 Aug 13;15(8). pii: E253. doi: 10.3390/md15080253.

16.

The cereal pathogen Fusarium pseudograminearum produces a new class of active cytokinins during infection.

Sørensen JL, Benfield AH, Wollenberg RD, Westphal K, Wimmer R, Nielsen MR, Nielsen KF, Carere J, Covarelli L, Beccari G, Powell J, Yamashino T, Kogler H, Sondergaard TE, Gardiner DM.

Mol Plant Pathol. 2018 May;19(5):1140-1154. doi: 10.1111/mpp.12593. Epub 2017 Oct 24.

PMID:
28802024
17.

Biosynthesis of the antimicrobial cyclic lipopeptides nunamycin and nunapeptin by Pseudomonas fluorescens strain In5 is regulated by the LuxR-type transcriptional regulator NunF.

Hennessy RC, Phippen CBW, Nielsen KF, Olsson S, Stougaard P.

Microbiologyopen. 2017 Dec;6(6). doi: 10.1002/mbo3.516. Epub 2017 Aug 6.

18.

Karmitoxin: An Amine-Containing Polyhydroxy-Polyene Toxin from the Marine Dinoflagellate Karlodinium armiger.

Rasmussen SA, Binzer SB, Hoeck C, Meier S, de Medeiros LS, Andersen NG, Place A, Nielsen KF, Hansen PJ, Larsen TO.

J Nat Prod. 2017 May 26;80(5):1287-1293. doi: 10.1021/acs.jnatprod.6b00860. Epub 2017 Apr 5.

19.

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species.

Nielsen JC, Grijseels S, Prigent S, Ji B, Dainat J, Nielsen KF, Frisvad JC, Workman M, Nielsen J.

Nat Microbiol. 2017 Apr 3;2:17044. doi: 10.1038/nmicrobiol.2017.44.

PMID:
28368369
20.

Effects of Gelling Agent and Extracellular Signaling Molecules on the Culturability of Marine Bacteria.

Rygaard AM, Thøgersen MS, Nielsen KF, Gram L, Bentzon-Tilia M.

Appl Environ Microbiol. 2017 Apr 17;83(9). pii: e00243-17. doi: 10.1128/AEM.00243-17. Print 2017 May 1.

21.

Dynamic Cluster Analysis: An Unbiased Method for Identifying A + 2 Element Containing Compounds in Liquid Chromatographic High-Resolution Time-of-Flight Mass Spectrometric Data.

Andersen AJ, Hansen PJ, Jørgensen K, Nielsen KF.

Anal Chem. 2016 Dec 20;88(24):12461-12469. doi: 10.1021/acs.analchem.6b03902. Epub 2016 Dec 6.

PMID:
28193030
22.

Global occurrence and heterogeneity of the Roseobacter-clade species Ruegeria mobilis.

Sonnenschein EC, Nielsen KF, D'Alvise P, Porsby CH, Melchiorsen J, Heilmann J, Kalatzis PG, López-Pérez M, Bunk B, Spröer C, Middelboe M, Gram L.

ISME J. 2017 Feb;11(2):588. doi: 10.1038/ismej.2016.125. No abstract available.

23.

Diversity and taxonomy of Chaetomium and chaetomium-like fungi from indoor environments.

Wang XW, Houbraken J, Groenewald JZ, Meijer M, Andersen B, Nielsen KF, Crous PW, Samson RA.

Stud Mycol. 2016 Jun;84:145-224. doi: 10.1016/j.simyco.2016.11.005. Epub 2016 Dec 8.

24.

Growth on Chitin Impacts the Transcriptome and Metabolite Profiles of Antibiotic-Producing Vibrio coralliilyticus S2052 and Photobacterium galatheae S2753.

Giubergia S, Phippen C, Nielsen KF, Gram L.

mSystems. 2017 Jan 3;2(1). pii: e00141-16. doi: 10.1128/mSystems.00141-16. eCollection 2017 Jan-Feb.

25.

Biofilm as a production platform for heterologous production of rhamnolipids by the non-pathogenic strain Pseudomonas putida KT2440.

Wigneswaran V, Nielsen KF, Sternberg C, Jensen PR, Folkesson A, Jelsbak L.

Microb Cell Fact. 2016 Oct 24;15(1):181.

26.

Diversity in Secondary Metabolites Including Mycotoxins from Strains of Aspergillus Section Nigri Isolated from Raw Cashew Nuts from Benin, West Africa.

Lamboni Y, Nielsen KF, Linnemann AR, Gezgin Y, Hell K, Nout MJ, Smid EJ, Tamo M, van Boekel MA, Hoof JB, Frisvad JC.

PLoS One. 2016 Oct 21;11(10):e0164310. doi: 10.1371/journal.pone.0164310. eCollection 2016.

27.

Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites.

Grijseels S, Nielsen JC, Randelovic M, Nielsen J, Nielsen KF, Workman M, Frisvad JC.

Sci Rep. 2016 Oct 14;6:35112. doi: 10.1038/srep35112.

28.

Production of the Bioactive Compounds Violacein and Indolmycin Is Conditional in a maeA Mutant of Pseudoalteromonas luteoviolacea S4054 Lacking the Malic Enzyme.

Thøgersen MS, Delpin MW, Melchiorsen J, Kilstrup M, Månsson M, Bunk B, Spröer C, Overmann J, Nielsen KF, Gram L.

Front Microbiol. 2016 Sep 16;7:1461. eCollection 2016.

29.

Global occurrence and heterogeneity of the Roseobacter-clade species Ruegeria mobilis.

Sonnenschein EC, Nielsen KF, D'Alvise P, Porsby CH, Melchiorsen J, Heilmann J, Kalatzis PG, López-Pérez M, Bunk B, Spröer C, Middelboe M, Gram L.

ISME J. 2017 Feb;11(2):569-583. doi: 10.1038/ismej.2016.111. Epub 2016 Aug 23. Erratum in: ISME J. 2017 Feb;11(2):588.

30.

Chemodiversity of Ladder-Frame Prymnesin Polyethers in Prymnesium parvum.

Rasmussen SA, Meier S, Andersen NG, Blossom HE, Duus JØ, Nielsen KF, Hansen PJ, Larsen TO.

J Nat Prod. 2016 Sep 23;79(9):2250-6. doi: 10.1021/acs.jnatprod.6b00345. Epub 2016 Aug 23.

PMID:
27550620
31.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N.

Nat Biotechnol. 2016 Aug 9;34(8):828-837. doi: 10.1038/nbt.3597.

32.

Stachybotrys mycotoxins: from culture extracts to dust samples.

Došen I, Andersen B, Phippen CB, Clausen G, Nielsen KF.

Anal Bioanal Chem. 2016 Aug;408(20):5513-26. doi: 10.1007/s00216-016-9649-y. Epub 2016 Jun 2.

33.

Production of the Fusarium Mycotoxin Moniliformin by Penicillium melanoconidium.

Hallas-Møller M, Nielsen KF, Frisvad JC.

J Agric Food Chem. 2016 Jun 8;64(22):4505-10. doi: 10.1021/acs.jafc.6b00298. Epub 2016 May 31.

PMID:
27195914
34.

Influence of Niche-Specific Nutrients on Secondary Metabolism in Vibrionaceae.

Giubergia S, Phippen C, Gotfredsen CH, Nielsen KF, Gram L.

Appl Environ Microbiol. 2016 Jun 13;82(13):4035-4044. doi: 10.1128/AEM.00730-16. Print 2016 Jul 1.

35.

Pre-contamination of new gypsum wallboard with potentially harmful fungal species.

Andersen B, Dosen I, Lewinska AM, Nielsen KF.

Indoor Air. 2017 Jan;27(1):6-12. doi: 10.1111/ina.12298. Epub 2016 Mar 31.

PMID:
26970063
36.

Identification of the non-ribosomal peptide synthetase responsible for biosynthesis of the potential anti-cancer drug sansalvamide in Fusarium solani.

Romans-Fuertes P, Sondergaard TE, Sandmann MI, Wollenberg RD, Nielsen KF, Hansen FT, Giese H, Brodersen DE, Sørensen JL.

Curr Genet. 2016 Nov;62(4):799-807. Epub 2016 Mar 2.

PMID:
26936154
37.

Isolation of TDA-producing Phaeobacter strains from sea bass larval rearing units and their probiotic effect against pathogenic Vibrio spp. in Artemia cultures.

Grotkjær T, Bentzon-Tilia M, D'Alvise P, Dourala N, Nielsen KF, Gram L.

Syst Appl Microbiol. 2016 May;39(3):180-188. doi: 10.1016/j.syapm.2016.01.005. Epub 2016 Feb 12.

PMID:
26922490
38.

Chemical Diversity, Origin, and Analysis of Phycotoxins.

Rasmussen SA, Andersen AJ, Andersen NG, Nielsen KF, Hansen PJ, Larsen TO.

J Nat Prod. 2016 Mar 25;79(3):662-73. doi: 10.1021/acs.jnatprod.5b01066. Epub 2016 Feb 22. Review.

PMID:
26901085
39.

Potentially harmful secondary metabolites produced by indoor Chaetomium species on artificially and naturally contaminated building materials.

Došen I, Nielsen KF, Clausen G, Andersen B.

Indoor Air. 2017 Jan;27(1):34-46. doi: 10.1111/ina.12290. Epub 2016 Mar 15.

PMID:
26880675
40.

Keep the sick from harm in spontaneous bacterial peritonitis: Dose of beta blockers matters.

Madsen BS, Nielsen KF, Fialla AD, Krag A.

J Hepatol. 2016 Jun;64(6):1455-6. doi: 10.1016/j.jhep.2016.01.031. Epub 2016 Feb 2. No abstract available.

PMID:
26845036
41.

Draft genome sequence and chemical profiling of Fusarium langsethiae, an emerging producer of type A trichothecenes.

Lysøe E, Frandsen RJ, Divon HH, Terzi V, Orrù L, Lamontanara A, Kolseth AK, Nielsen KF, Thrane U.

Int J Food Microbiol. 2016 Mar 16;221:29-36. doi: 10.1016/j.ijfoodmicro.2016.01.008. Epub 2016 Jan 12.

PMID:
26803271
42.

Identification of a Classical Mutant in the Industrial Host Aspergillus niger by Systems Genetics: LaeA Is Required for Citric Acid Production and Regulates the Formation of Some Secondary Metabolites.

Niu J, Arentshorst M, Nair PD, Dai Z, Baker SE, Frisvad JC, Nielsen KF, Punt PJ, Ram AF.

G3 (Bethesda). 2015 Nov 13;6(1):193-204. doi: 10.1534/g3.115.024067.

43.

Rumen microbial communities influence metabolic phenotypes in lambs.

Morgavi DP, Rathahao-Paris E, Popova M, Boccard J, Nielsen KF, Boudra H.

Front Microbiol. 2015 Oct 12;6:1060. doi: 10.3389/fmicb.2015.01060. eCollection 2015.

44.

Influence of Iron on Production of the Antibacterial Compound Tropodithietic Acid and Its Noninhibitory Analog in Phaeobacter inhibens.

D'Alvise PW, Phippen CB, Nielsen KF, Gram L.

Appl Environ Microbiol. 2015 Oct 30;82(2):502-9. doi: 10.1128/AEM.02992-15. Print 2016 Jan 15.

45.

Dichlorinated and Brominated Rugulovasines, Ergot Alkaloids Produced by Talaromyces wortmannii.

de Medeiros LS, da Silva JV, Abreu LM, Pfenning LH, Silva CL, Thomasi SS, Venâncio T, van Pée KH, Nielsen KF, Rodrigues-Filho E.

Molecules. 2015 Sep 23;20(9):17627-44. doi: 10.3390/molecules200917627.

46.
47.

Quantifying intracellular metabolites in yeast using a matrix with minimal interference from naturally occurring analytes.

Magdenoska O, Knudsen PB, Svenssen DK, Nielsen KF.

Anal Biochem. 2015 Oct 15;487:17-26. doi: 10.1016/j.ab.2015.06.033. Epub 2015 Jul 2.

PMID:
26142219
48.

Combining UHPLC-High Resolution MS and Feeding of Stable Isotope Labeled Polyketide Intermediates for Linking Precursors to End Products.

Klitgaard A, Frandsen RJ, Holm DK, Knudsen PB, Frisvad JC, Nielsen KF.

J Nat Prod. 2015 Jul 24;78(7):1518-25. doi: 10.1021/np500979d. Epub 2015 Jul 1.

PMID:
26132344
49.

Combining Stable Isotope Labeling and Molecular Networking for Biosynthetic Pathway Characterization.

Klitgaard A, Nielsen JB, Frandsen RJ, Andersen MR, Nielsen KF.

Anal Chem. 2015 Jul 7;87(13):6520-6. doi: 10.1021/acs.analchem.5b01934. Epub 2015 Jun 9.

PMID:
26020678
50.

Stepwise emergence of azole, echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations.

Jensen RH, Astvad KM, Silva LV, Sanglard D, Jørgensen R, Nielsen KF, Mathiasen EG, Doroudian G, Perlin DS, Arendrup MC.

J Antimicrob Chemother. 2015 Sep;70(9):2551-5. doi: 10.1093/jac/dkv140. Epub 2015 May 27.

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