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Epistatic regulation of growth in Atlantic salmon revealed: a QTL study performed on the domesticated-wild interface.

Besnier F, Solberg MF, Harvey AC, Carvalho GR, Bekkevold D, Taylor MI, Creer S, Nielsen EE, Skaala Ø, Ayllon F, Dahle G, Glover KA.

BMC Genet. 2020 Feb 7;21(1):13. doi: 10.1186/s12863-020-0816-y.


Northern European Salmo trutta (L.) populations are genetically divergent across geographical regions and environmental gradients.

Bekkevold D, Höjesjö J, Nielsen EE, Aldvén D, Als TD, Sodeland M, Kent MP, Lien S, Hansen MM.

Evol Appl. 2019 Nov 1;13(2):400-416. doi: 10.1111/eva.12877. eCollection 2020 Feb.


Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how.

Nørskov AK, Lange T, Nielsen EE, Gluud C, Winkel P, Beyersmann J, de Uña-Álvarez J, Torri V, Billot L, Putter H, Wetterslev J, Thabane L, Jakobsen JC.

BMJ Evid Based Med. 2020 Jan 27. pii: bmjebm-2019-111268. doi: 10.1136/bmjebm-2019-111268. [Epub ahead of print]


Extension of pharmacokinetic/pharmacodynamic (PK/PD) time-kill studies to include LPS/endotoxin release from E. coli exposed to cefuroxime.

Thorsted A, Tano E, Kaivonen K, Sjölin J, Friberg LE, Nielsen EI.

Antimicrob Agents Chemother. 2020 Jan 27. pii: AAC.02070-19. doi: 10.1128/AAC.02070-19. [Epub ahead of print]


Doxazosin treatment in cocaine use disorder: pharmacogenetic response based on an alpha-1 adrenoreceptor subtype D genetic variant.

Shorter DI, Zhang X, Domingo CB, Nielsen EM, Kosten TR, Nielsen DA.

Am J Drug Alcohol Abuse. 2020 Jan 8:1-10. doi: 10.1080/00952990.2019.1674864. [Epub ahead of print]


Adding exercise to usual care in patients with hypertension, type 2 diabetes mellitus and/or cardiovascular disease: a protocol for a systematic review with meta-analysis and trial sequential analysis.

Rijal A, Nielsen EE, Hemmingsen B, Neupane D, Gæde PH, Olsen MH, Jakobsen JC.

Syst Rev. 2019 Dec 17;8(1):330. doi: 10.1186/s13643-019-1233-z.


Beta-blockers for suspected or diagnosed acute myocardial infarction.

Safi S, Sethi NJ, Nielsen EE, Feinberg J, Jakobsen JC, Gluud C.

Cochrane Database Syst Rev. 2019 Dec 17;12:CD012484. doi: 10.1002/14651858.CD012484.pub2. Review.


A Cross-Sectional Study Assessing Appropriateness Of Inhaled Corticosteroid Treatment In Primary And Secondary Care Patients With COPD In Sweden.

Sulku J, Janson C, Melhus H, Malinovschi A, Ställberg B, Bröms K, Högman M, Lisspers K, Hammarlund-Udenaes M, Nielsen EI.

Int J Chron Obstruct Pulmon Dis. 2019 Nov 5;14:2451-2460. doi: 10.2147/COPD.S218747. eCollection 2019.


The problem of standardized breast cancer narratives.

Nielsen E.

CMAJ. 2019 Nov 25;191(47):E1311-E1312. doi: 10.1503/cmaj.190549. No abstract available.


Author Correction: Gene-associated markers provide tools for tackling illegal fishing and false eco-certification.

Nielsen EE, Cariani A, Aoidh EM, Maes GE, Milano I, Ogden R, Taylor M, Hemmer-Hansen J, Babbucci M, Bargelloni L, Bekkevold D, Diopere E, Grenfell L, Helyar S, Limborg MT, Martinsohn JT, McEwing R, Panitz F, Patarnello T, Tinti F, Van Houdt JKJ, Volckaert FAM, Waples RS; FishPopTrace Consortium, Carvalho GR.

Nat Commun. 2019 Nov 22;10(1):5325. doi: 10.1038/s41467-019-13399-5.


WGS based study of the population structure of Salmonella enterica serovar Infantis.

Gymoese P, Kiil K, Torpdahl M, Østerlund MT, Sørensen G, Olsen JE, Nielsen EM, Litrup E.

BMC Genomics. 2019 Nov 15;20(1):870. doi: 10.1186/s12864-019-6260-6.


A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria.

Kristoffersson AN, Bissantz C, Okujava R, Haldimann A, Walter I, Shi T, Zampaloni C, Nielsen EI.

J Antimicrob Chemother. 2020 Feb 1;75(2):400-408. doi: 10.1093/jac/dkz440.


Bayesian Forecasting Utilizing Bleeding Information to Support Dose Individualization of Factor VIII.

Abrantes JA, Solms A, Garmann D, Nielsen EI, Jönsson S, Karlsson MO.

CPT Pharmacometrics Syst Pharmacol. 2019 Dec;8(12):894-903. doi: 10.1002/psp4.12464. Epub 2019 Oct 30.


Coronary artery bypass surgery plus medical therapy versus medical therapy alone for ischaemic heart disease: a protocol for a systematic review with meta-analysis and trial sequential analysis.

Lorenzen US, Buggeskov KB, Nielsen EE, Sethi NJ, Carranza CL, Gluud C, Jakobsen JC.

Syst Rev. 2019 Oct 28;8(1):246. doi: 10.1186/s13643-019-1155-9.


Erratum to: Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen.

Thorsted A, Kristoffersson AN, Maarbjerg SF, Schrøder H, Wang M, Brock B, Nielsen EI, Friberg LE.

J Antimicrob Chemother. 2020 Jan 1;75(1):254-255. doi: 10.1093/jac/dkz429. No abstract available.


The impact of dietary habits on contaminant exposures.

Petersen A, Jensen BH, Löbl NM, Nielsen E, Bredsdorff L, Fagt S, Christensen T, Boberg J.

Food Chem Toxicol. 2020 Jan;135:110885. doi: 10.1016/j.fct.2019.110885. Epub 2019 Oct 15.


Comparison of Ponte Osteotomies and 3-Column Osteotomies in the Treatment of Congenital Spinal Deformity.

Chan P, Andras LM, Nielsen E, Sousa T, Joiner E, Choi PD, Tolo VT, Skaggs DL.

J Pediatr Orthop. 2019 Nov/Dec;39(10):495-499. doi: 10.1097/BPO.0000000000001057.


Elbow Biomechanics, Radiocapitellar Joint Pressure, and Interosseous Membrane Strain Before and After Radial Head Arthroplasty.

Hemmingsen CK, Thillemann TM, Elmengaard B, de Raedt S, Nielsen ET, Mosegaard SB, Stentz-Olesen K, Stilling M.

J Orthop Res. 2020 Mar;38(3):510-522. doi: 10.1002/jor.24488. Epub 2019 Oct 15.


Direct Randomized Benchmarking for Multiqubit Devices.

Proctor TJ, Carignan-Dugas A, Rudinger K, Nielsen E, Blume-Kohout R, Young K.

Phys Rev Lett. 2019 Jul 19;123(3):030503. doi: 10.1103/PhysRevLett.123.030503.


Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients.

Abrantes JA, Solms A, Garmann D, Nielsen EI, Jönsson S, Karlsson MO.

Haematologica. 2019 Aug 1. pii: haematol.2019.217133. doi: 10.3324/haematol.2019.217133. [Epub ahead of print]


"These Things Don't Work." Young People's Views on Harm Minimization Strategies as a Proxy for Self-Harm: A Mixed Methods Approach.

Wadman R, Nielsen E, O'Raw L, Brown K, Williams AJ, Sayal K, Townsend E.

Arch Suicide Res. 2019 Jul 19:1-18. doi: 10.1080/13811118.2019.1624669. [Epub ahead of print]


Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen.

Thorsted A, Kristoffersson AN, Maarbjerg SF, Schrøder H, Wang M, Brock B, Nielsen EI, Friberg LE.

J Antimicrob Chemother. 2019 Oct 1;74(10):2984-2993. doi: 10.1093/jac/dkz270.


Changes in Pediatric Spine Surgery Patterns Over the Last 10 Years Among ABOS Part II Candidates.

Nielsen E, Andras LM, Hosseinzadeh P, Mignemi M, Sawyer JR, Flynn JM, Albanese S, Skaggs DL.

Spine (Phila Pa 1976). 2019 Sep;44(18):E1103-E1107. doi: 10.1097/BRS.0000000000003072.


Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model.

Pischke SE, Hestenes S, Johansen HT, Fure H, Bugge JF, Espinoza A, Skulstad H, Edvardsen T, Fosse E, Mollnes TE, Halvorsen PS, Nielsen EW.

PLoS One. 2019 Jun 27;14(6):e0218624. doi: 10.1371/journal.pone.0218624. eCollection 2019.


Toward Understanding the Relationship Between Prioritized Values and Preferences for Cardiopulmonary Resuscitation Among Seriously Ill Adults.

Modes ME, Engelberg RA, Downey L, Nielsen EL, Lee RY, Curtis JR, Kross EK.

J Pain Symptom Manage. 2019 Oct;58(4):567-577.e1. doi: 10.1016/j.jpainsymman.2019.06.011. Epub 2019 Jun 19.


Language use and suicide: An online cross-sectional survey.

Padmanathan P, Biddle L, Hall K, Scowcroft E, Nielsen E, Knipe D.

PLoS One. 2019 Jun 13;14(6):e0217473. doi: 10.1371/journal.pone.0217473. eCollection 2019.


Supported and valued? A survey of early career researchers' experiences and perceptions of youth and adult involvement in mental health, self-harm and suicide research.

Wadman R, Williams AJ, Brown K, Nielsen E.

Res Involv Engagem. 2019 Apr 29;5:16. doi: 10.1186/s40900-019-0149-z. eCollection 2019.


Simultaneous Measurements of Tension and Free H2S in Mesenteric Arteries.

Nielsen ER, Winther AK, Simonsen U.

Methods Mol Biol. 2019;2007:125-136. doi: 10.1007/978-1-4939-9528-8_9.


Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14.

Skjeflo EW, Christiansen D, Landsem A, Stenvik J, Woodruff TM, Espevik T, Nielsen EW, Mollnes TE.

Mol Immunol. 2019 Aug;112:131-139. doi: 10.1016/j.molimm.2019.03.014. Epub 2019 May 15.


Pharmacogenetic role of dopamine transporter (SLC6A3) variation on response to disulfiram treatment for cocaine addiction.

Kampangkaew JP, Spellicy CJ, Nielsen EM, Harding MJ, Ye A, Hamon SC, Kosten TR, Nielsen DA.

Am J Addict. 2019 Jul;28(4):311-317. doi: 10.1111/ajad.12891. Epub 2019 May 14.


Improvement of phytochemical production by plant cells and organ culture and by genetic engineering.

Nielsen E, Temporiti MEE, Cella R.

Plant Cell Rep. 2019 Oct;38(10):1199-1215. doi: 10.1007/s00299-019-02415-z. Epub 2019 May 4. Review.


Genetic analyses reveal complex dynamics within a marine fish management area.

Hemmer-Hansen J, Hüssy K, Baktoft H, Huwer B, Bekkevold D, Haslob H, Herrmann JP, Hinrichsen HH, Krumme U, Mosegaard H, Nielsen EE, Reusch TBH, Storr-Paulsen M, Velasco A, von Dewitz B, Dierking J, Eero M.

Evol Appl. 2019 Jan 20;12(4):830-844. doi: 10.1111/eva.12760. eCollection 2019 Apr.


Pharmacokinetics of Caspofungin in Critically Ill Patients in Relation to Liver Dysfunction: Differential Impact of Plasma Albumin and Bilirubin Levels.

Kurland S, Furebring M, Löwdin E, Eliasson E, Nielsen EI, Sjölin J.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e02466-18. doi: 10.1128/AAC.02466-18. Print 2019 Jun.


Assessing assumptions for statistical analyses in randomised clinical trials.

Nielsen EE, Nørskov AK, Lange T, Thabane L, Wetterslev J, Beyersmann J, de Uña-Álvarez J, Torri V, Billot L, Putter H, Winkel P, Gluud C, Jakobsen JC.

BMJ Evid Based Med. 2019 Oct;24(5):185-189. doi: 10.1136/bmjebm-2019-111174. Epub 2019 Apr 4.


Modeling cocaine traffickers and counterdrug interdiction forces as a complex adaptive system.

Magliocca NR, McSweeney K, Sesnie SE, Tellman E, Devine JA, Nielsen EA, Pearson Z, Wrathall DJ.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7784-7792. doi: 10.1073/pnas.1812459116. Epub 2019 Apr 1.


A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6.

Thorsted A, Bouchene S, Tano E, Castegren M, Lipcsey M, Sjölin J, Karlsson MO, Friberg LE, Nielsen EI.

PLoS One. 2019 Feb 21;14(2):e0211981. doi: 10.1371/journal.pone.0211981. eCollection 2019.


Handling interoccasion variability in model-based dose individualization using therapeutic drug monitoring data.

Abrantes JA, Jönsson S, Karlsson MO, Nielsen EI.

Br J Clin Pharmacol. 2019 Jun;85(6):1326-1336. doi: 10.1111/bcp.13901. Epub 2019 Apr 29.


Piperacillin pharmacokinetics and target attainment in children with cancer and fever: Can we optimize our dosing strategy?

Maarbjerg SF, Thorsted A, Kristoffersson A, Friberg LE, Nielsen EI, Wang M, Brock B, Schrøder H.

Pediatr Blood Cancer. 2019 Jun;66(6):e27654. doi: 10.1002/pbc.27654. Epub 2019 Feb 10.


A successful new method for single left lobe recruitment.

Dybwik K, Nielsen EW.

Clin Case Rep. 2018 Oct 18;6(12):2309-2312. doi: 10.1002/ccr3.1787. eCollection 2018 Dec.


Determinants of sporadic Campylobacter infections in Denmark: a nationwide case-control study among children and young adults.

Kuhn KG, Nielsen EM, Mølbak K, Ethelberg S.

Clin Epidemiol. 2018 Nov 21;10:1695-1707. doi: 10.2147/CLEP.S177141. eCollection 2018.


Did a Goals-of-Care Discussion Happen? Differences in the Occurrence of Goals-of-Care Discussions as Reported by Patients, Clinicians, and in the Electronic Health Record.

Modes ME, Engelberg RA, Downey L, Nielsen EL, Curtis JR, Kross EK.

J Pain Symptom Manage. 2019 Feb;57(2):251-259. doi: 10.1016/j.jpainsymman.2018.10.507. Epub 2018 Nov 1.


Pediatric Sports Medicine, A New Subspeciality in Orthopedics: An Analysis of the Surgical Volume of Candidates for the American Board of Orthopaedic Surgery Part II Certification Exam Over the Past Decade.

Obey MR, Lamplot J, Nielsen ED, Andras LM, Mignemi M, Sawyer J, Flynn JM, Albanese SA, Hosseinzadeh P.

J Pediatr Orthop. 2019 Jan;39(1):e71-e76. doi: 10.1097/BPO.0000000000001276.


Orthopaedic Care for Children: Who Provides It? How Has It Changed Over the Past Decade? Analysis of the Database of the American Board of Orthopaedic Surgery.

Hosseinzadeh P, Obey MR, Nielsen E, Andras L, Kiebzak GM, Mignemi M, Sawyer JR, Albanese S, Flynn JM.

J Pediatr Orthop. 2019 Mar;39(3):e227-e231. doi: 10.1097/BPO.0000000000001277.


Optimizing Osteogenic Differentiation of Ovine Adipose-Derived Stem Cells by Osteogenic Induction Medium and FGFb, BMP2, or NELL1 In Vitro.

Nielsen EØ, Chen L, Hansen JO, Degn M, Overgaard S, Ding M.

Stem Cells Int. 2018 Sep 26;2018:9781393. doi: 10.1155/2018/9781393. eCollection 2018.


Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs.

Lillethorup TP, Glud AN, Alstrup AKO, Noer O, Nielsen EHT, Schacht AC, Landeck N, Kirik D, Orlowski D, Sørensen JCH, Doudet DJ, Landau AM.

Sci Rep. 2018 Oct 24;8(1):15715. doi: 10.1038/s41598-018-34084-5.


Don't You Wish You Had Fused to the Pelvis the First Time: A Comparison of Reoperation Rate and Correction of Pelvic Obliquity.

Nielsen E, Andras LM, Bellaire LL, Fletcher ND, Minkara A, Vitale MG, Troy M, Glotzbecker M, Skaggs DL.

Spine (Phila Pa 1976). 2019 Apr 15;44(8):E465-E469. doi: 10.1097/BRS.0000000000002888.


Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurisation - a pilot study.

Nielsen ES, Garnås E, Jensen KJ, Hansen LH, Olsen PS, Ritz C, Krych L, Nielsen DS.

Food Funct. 2018 Oct 17;9(10):5323-5335. doi: 10.1039/c8fo00968f.


Validation of Catquest-9SF in Danish: developing a revised form of the Catquest-9SF - the Danish Catquest-7SF.

Nielsen E, Lundström M, Pesudovs K, Hjortdal J.

Acta Ophthalmol. 2019 Mar;97(2):173-177. doi: 10.1111/aos.13921. Epub 2018 Sep 21.


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