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Items: 1 to 50 of 64

1.

Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases.

Holzer T, Probst K, Etich J, Auler M, Georgieva VS, Bluhm B, Frie C, Heilig J, Niehoff A, Nüchel J, Plomann M, Seeger JM, Kashkar H, Baris OR, Wiesner RJ, Brachvogel B.

J Cell Biol. 2019 May 13. pii: jcb.201809056. doi: 10.1083/jcb.201809056. [Epub ahead of print]

PMID:
31085560
2.

Complementary Molecular and Elemental Mass-Spectrometric Imaging of Human Brain Tumors Resected by Fluorescence-Guided Surgery.

Kröger S, Niehoff AC, Jeibmann A, Sperling M, Paulus W, Stummer W, Karst U.

Anal Chem. 2018 Oct 16;90(20):12253-12260. doi: 10.1021/acs.analchem.8b03516. Epub 2018 Oct 2.

PMID:
30215510
3.

Plastin 3 influences bone homeostasis through regulation of osteoclast activity.

Neugebauer J, Heilig J, Hosseinibarkooie S, Ross BC, Mendoza-Ferreira N, Nolte F, Peters M, Hölker I, Hupperich K, Tschanz T, Grysko V, Zaucke F, Niehoff A, Wirth B.

Hum Mol Genet. 2018 Dec 15;27(24):4249-4262. doi: 10.1093/hmg/ddy318.

PMID:
30204862
4.

Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function.

Probst K, Stermann J, von Bomhard I, Etich J, Pitzler L, Niehoff A, Bluhm B, Xu HC, Lang PA, Chmielewski M, Abken H, Blissenbach B, Machova A, Papadopoulou N, Brachvogel B.

Stem Cells. 2018 Nov;36(11):1752-1763. doi: 10.1002/stem.2892. Epub 2018 Sep 11.

PMID:
30063808
5.

Effect of increased mechanical knee joint loading during running on the serum concentration of cartilage oligomeric matrix protein (COMP).

Firner S, Willwacher S, de Marées M, Bleuel J, Zaucke F, Brüggemann GP, Niehoff A.

J Orthop Res. 2018 Jul;36(7):1937-1946. doi: 10.1002/jor.23859. Epub 2018 Feb 13.

PMID:
29369406
6.

Spatially resolved quantification of gadolinium deposited in the brain of a patient treated with gadolinium-based contrast agents.

Fingerhut S, Niehoff AC, Sperling M, Jeibmann A, Paulus W, Niederstadt T, Allkemper T, Heindel W, Holling M, Karst U.

J Trace Elem Med Biol. 2018 Jan;45:125-130. doi: 10.1016/j.jtemb.2017.10.004. Epub 2017 Oct 13.

PMID:
29173468
7.

Combinatory effects of phytoestrogens and exercise on body fat mass and lipid metabolism in ovariectomized female rats.

Zheng W, Rogoschin J, Niehoff A, Oden K, Kulling SE, Xie M, Diel P.

J Steroid Biochem Mol Biol. 2018 Apr;178:73-81. doi: 10.1016/j.jsbmb.2017.11.002. Epub 2017 Nov 6.

PMID:
29122708
8.

Investigating the Lymphatic System by Dual-Color Elemental Mass Spectrometry Imaging.

Niehoff AC, Klasen T, Schmidt R, Palmes D, Faber C, Karst U, Hadrian R.

Contrast Media Mol Imaging. 2017 Jan 29;2017:4035721. doi: 10.1155/2017/4035721. eCollection 2017.

9.

The influence of cryopreservation and quick-freezing on the mechanical properties of tendons.

Oswald I, Rickert M, Brüggemann GP, Niehoff A, Fonseca Ulloa CA, Jahnke A.

J Biomech. 2017 Nov 7;64:226-230. doi: 10.1016/j.jbiomech.2017.08.018. Epub 2017 Aug 26.

PMID:
28893393
10.

miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage.

Bluhm B, Ehlen HWA, Holzer T, Georgieva VS, Heilig J, Pitzler L, Etich J, Bortecen T, Frie C, Probst K, Niehoff A, Belluoccio D, Van den Bergen J, Brachvogel B.

Development. 2017 Oct 1;144(19):3562-3577. doi: 10.1242/dev.148429. Epub 2017 Aug 29.

11.

Extracellular Distribution of Collagen II and Perifibrillar Adapter Proteins in Healthy and Osteoarthritic Human Knee Joint Cartilage.

Firner S, Zaucke F, Michael J, Dargel J, Schiwy-Bochat KH, Heilig J, Rothschild MA, Eysel P, Brüggemann GP, Niehoff A.

J Histochem Cytochem. 2017 Oct;65(10):593-606. doi: 10.1369/0022155417729154. Epub 2017 Aug 28.

12.

Quantitative bioimaging of platinum group elements in tumor spheroids.

Niehoff AC, Grünebaum J, Moosmann A, Mulac D, Söbbing J, Niehaus R, Buchholz R, Kröger S, Wiehe A, Wagner S, Sperling M, von Briesen H, Langer K, Karst U.

Anal Chim Acta. 2016 Sep 28;938:106-13. doi: 10.1016/j.aca.2016.07.021. Epub 2016 Jul 25.

PMID:
27619092
13.

Imaging by Elemental and Molecular Mass Spectrometry Reveals the Uptake of an Arsenolipid in the Brain of Drosophila melanogaster.

Niehoff AC, Schulz J, Soltwisch J, Meyer S, Kettling H, Sperling M, Jeibmann A, Dreisewerd K, Francesconi KA, Schwerdtle T, Karst U.

Anal Chem. 2016 May 17;88(10):5258-63. doi: 10.1021/acs.analchem.6b00333. Epub 2016 May 2.

PMID:
27098356
14.

Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin.

Zigrino P, Brinckmann J, Niehoff A, Lu Y, Giebeler N, Eckes B, Kadler KE, Mauch C.

J Invest Dermatol. 2016 Aug;136(8):1575-1583. doi: 10.1016/j.jid.2016.03.036. Epub 2016 Apr 9.

15.

Laser desorption/ionization mass spectrometry of lipids using etched silver substrates.

Schnapp A, Niehoff AC, Koch A, Dreisewerd K.

Methods. 2016 Jul 15;104:194-203. doi: 10.1016/j.ymeth.2016.01.014. Epub 2016 Jan 28.

PMID:
26827933
16.

COMP-assisted collagen secretion--a novel intracellular function required for fibrosis.

Schulz JN, Nüchel J, Niehoff A, Bloch W, Schönborn K, Hayashi S, Kamper M, Brinckmann J, Plomann M, Paulsson M, Krieg T, Zaucke F, Eckes B.

J Cell Sci. 2016 Feb 15;129(4):706-16. doi: 10.1242/jcs.180216. Epub 2016 Jan 8.

17.

Dose-dependent effects of isoflavone exposure during early lifetime on development and androgen sensitivity in male Wistar rats.

Müller DR, Basso F, Kurrat A, Soukup ST, Niehoff A, Kulling SE, Diel P.

Mol Nutr Food Res. 2016 Feb;60(2):325-36. doi: 10.1002/mnfr.201500559. Epub 2015 Dec 7.

PMID:
26573877
18.

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair.

Knipper JA, Willenborg S, Brinckmann J, Bloch W, Maaß T, Wagener R, Krieg T, Sutherland T, Munitz A, Rothenberg ME, Niehoff A, Richardson R, Hammerschmidt M, Allen JE, Eming SA.

Immunity. 2015 Oct 20;43(4):803-16. doi: 10.1016/j.immuni.2015.09.005.

19.

Early changes in morphology, bone mineral density and matrix composition of vertebrae lead to disc degeneration in aged collagen IX -/- mice.

Kamper M, Hamann N, Prein C, Clausen-Schaumann H, Farkas Z, Aszodi A, Niehoff A, Paulsson M, Zaucke F.

Matrix Biol. 2016 Jan;49:132-143. doi: 10.1016/j.matbio.2015.09.005. Epub 2015 Sep 30.

PMID:
26429145
20.

Quantitative Bioimaging to Investigate the Uptake of Mercury Species in Drosophila melanogaster.

Niehoff AC, Bauer OB, Kröger S, Fingerhut S, Schulz J, Meyer S, Sperling M, Jeibmann A, Schwerdtle T, Karst U.

Anal Chem. 2015 Oct 20;87(20):10392-6. doi: 10.1021/acs.analchem.5b02500. Epub 2015 Oct 7.

PMID:
26424032
21.

Biomechanical comparison of transosseous re-fixation of the deep fibres of the distal radioulnar ligaments versus deep and superficial fibres: a cadaver study.

Spies CK, Niehoff A, Unglaub F, Müller LP, Langer MF, Neiss WF, Oppermann J.

Int Orthop. 2016 Feb;40(2):315-21. doi: 10.1007/s00264-015-2986-1. Epub 2015 Sep 22.

PMID:
26395009
22.

Effects of cyclic tensile strain on chondrocyte metabolism: a systematic review.

Bleuel J, Zaucke F, Brüggemann GP, Niehoff A.

PLoS One. 2015 Mar 30;10(3):e0119816. doi: 10.1371/journal.pone.0119816. eCollection 2015. Review.

23.

Moderate cyclic tensile strain alters the assembly of cartilage extracellular matrix proteins in vitro.

Bleuel J, Zaucke F, Brüggemann GP, Heilig J, Wolter ML, Hamann N, Firner S, Niehoff A.

J Biomech Eng. 2015 Jun;137(6):061009. doi: 10.1115/1.4030053. Epub 2015 Apr 14.

PMID:
25782164
24.

Reduced granulation tissue and wound strength in the absence of α11β1 integrin.

Schulz JN, Zeltz C, Sørensen IW, Barczyk M, Carracedo S, Hallinger R, Niehoff A, Eckes B, Gullberg D.

J Invest Dermatol. 2015 May;135(5):1435-1444. doi: 10.1038/jid.2015.24. Epub 2015 Jan 29.

25.

Rapid cell mode switching and dual laser ablation inductively coupled plasma mass spectrometry for elemental bioimaging.

Wehe CA, Niehoff AC, Thyssen GM, Sperling M, Karst U.

Rapid Commun Mass Spectrom. 2014 Dec 15;28(23):2627-35. doi: 10.1002/rcm.7054.

PMID:
25366409
26.

Analysis of Drosophila lipids by matrix-assisted laser desorption/ionization mass spectrometric imaging.

Niehoff AC, Kettling H, Pirkl A, Chiang YN, Dreisewerd K, Yew JY.

Anal Chem. 2014 Nov 18;86(22):11086-92. doi: 10.1021/ac503171f. Epub 2014 Nov 5.

PMID:
25329240
27.

Col6a1 null mice as a model to study skin phenotypes in patients with collagen VI related myopathies: expression of classical and novel collagen VI variants during wound healing.

Lettmann S, Bloch W, Maaß T, Niehoff A, Schulz JN, Eckes B, Eming SA, Bonaldo P, Paulsson M, Wagener R.

PLoS One. 2014 Aug 26;9(8):e105686. doi: 10.1371/journal.pone.0105686. eCollection 2014.

28.

Effect of exercise-induced enhancement of the leg-extensor muscle-tendon unit capacities on ambulatory mechanics and knee osteoarthritis markers in the elderly.

Karamanidis K, Oberländer KD, Niehoff A, Epro G, Brüggemann GP.

PLoS One. 2014 Jun 6;9(6):e99330. doi: 10.1371/journal.pone.0099330. eCollection 2014.

29.

Topographical variations in articular cartilage and subchondral bone of the normal rat knee are age-related.

Hamann N, Brüggemann GP, Niehoff A.

Ann Anat. 2014 Sep;196(5):278-85. doi: 10.1016/j.aanat.2014.04.006. Epub 2014 May 13.

PMID:
24889323
30.

A palladium label to monitor nanoparticle-assisted drug delivery of a photosensitizer into tumor spheroids by elemental bioimaging.

Niehoff AC, Moosmann A, Söbbing J, Wiehe A, Mulac D, Wehe CA, Reifschneider O, Blaske F, Wagner S, Sperling M, von Briesen H, Langer K, Karst U.

Metallomics. 2014 Jan;6(1):77-81. doi: 10.1039/c3mt00223c.

PMID:
24311052
31.

Effect of whole-body vibration and insulin-like growth factor-I on muscle paralysis-induced bone degeneration after botulinum toxin injection in mice.

Niehoff A, Lechner P, Ratiu O, Reuter S, Hamann N, Brüggemann GP, Schönau E, Bloch W, Beccard R.

Calcif Tissue Int. 2014 Apr;94(4):373-83. doi: 10.1007/s00223-013-9818-3. Epub 2013 Nov 29.

PMID:
24292598
32.

Elucidation of the structure of poly(γ-benzyl-l-glutamate) nanofibers and gel networks in a helicogenic solvent.

Niehoff A, Mantion A, McAloney R, Huber A, Falkenhagen J, Goh CM, Thünemann AF, Winnik MA, Menzel H.

Colloid Polym Sci. 2013 Jun;291(6):1353-1363. Epub 2012 Dec 14.

33.

Doxycycline-induced expression of transgenic human tumor necrosis factor α in adult mice results in psoriasis-like arthritis.

Retser E, Schied T, Skryabin BV, Vogl T, Kanczler JM, Hamann N, Niehoff A, Hermann S, Eisenblätter M, Wachsmuth L, Pap T, van Lent PL, Loser K, Roth J, Zaucke F, Ludwig S, Wixler V.

Arthritis Rheum. 2013 Sep;65(9):2290-300. doi: 10.1002/art.38026.

34.

Growth-related structural, biochemical, and mechanical properties of the functional bone-cartilage unit.

Hamann N, Zaucke F, Dayakli M, Brüggemann GP, Niehoff A.

J Anat. 2013 Feb;222(2):248-59. doi: 10.1111/joa.12003. Epub 2012 Oct 22.

35.

Effect of different running modes on the morphological, biochemical, and mechanical properties of articular cartilage.

Hamann N, Zaucke F, Heilig J, Oberländer KD, Brüggemann GP, Niehoff A.

Scand J Med Sci Sports. 2014 Feb;24(1):179-88. doi: 10.1111/j.1600-0838.2012.01513.x. Epub 2012 Aug 13.

PMID:
22889098
36.

Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response.

Grskovic I, Kutsch A, Frie C, Groma G, Stermann J, Schlötzer-Schrehardt U, Niehoff A, Moss SE, Rosenbaum S, Pöschl E, Chmielewski M, Rappl G, Abken H, Bateman JF, Cheah KS, Paulsson M, Brachvogel B.

J Bone Miner Res. 2012 Nov;27(11):2399-412. doi: 10.1002/jbmr.1682.

37.

Effect of pendant group structure on the hydrolytic stability of polyaspartamide polymers under physiological conditions.

Lu Y, Chau M, Boyle AJ, Liu P, Niehoff A, Weinrich D, Reilly RM, Winnik MA.

Biomacromolecules. 2012 May 14;13(5):1296-306. doi: 10.1021/bm2018239. Epub 2012 Apr 3.

PMID:
22471754
38.

The effect of level and downhill running on cortical and trabecular bone in growing rats.

Hamann N, Kohler T, Müller R, Brüggemann GP, Niehoff A.

Calcif Tissue Int. 2012 May;90(5):429-37. doi: 10.1007/s00223-012-9593-6. Epub 2012 Apr 1.

PMID:
22466445
39.

Abnormal bone quality in cartilage oligomeric matrix protein and matrilin 3 double-deficient mice caused by increased tissue inhibitor of metalloproteinases 3 deposition and delayed aggrecan degradation.

Groma G, Xin W, Grskovic I, Niehoff A, Brachvogel B, Paulsson M, Zaucke F.

Arthritis Rheum. 2012 Aug;64(8):2644-54. doi: 10.1002/art.34435.

40.

Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels.

Blumbach K, Niehoff A, Belgardt BF, Ehlen HW, Schmitz M, Hallinger R, Schulz JN, Brüning JC, Krieg T, Schubert M, Gullberg D, Eckes B.

J Biol Chem. 2012 Feb 24;287(9):6431-40. doi: 10.1074/jbc.M111.283119. Epub 2011 Dec 30.

41.

Deformational behaviour of knee cartilage and changes in serum cartilage oligomeric matrix protein (COMP) after running and drop landing.

Niehoff A, Müller M, Brüggemann L, Savage T, Zaucke F, Eckstein F, Müller-Lung U, Brüggemann GP.

Osteoarthritis Cartilage. 2011 Aug;19(8):1003-10. doi: 10.1016/j.joca.2011.04.012. Epub 2011 May 12.

42.

Effect of exercise on bone and articular cartilage in heterozygous manganese superoxide dismutase (SOD2) deficient mice.

Baur A, Henkel J, Bloch W, Treiber N, Scharffetter-Kochanek K, Brüggemann GP, Niehoff A.

Free Radic Res. 2011 May;45(5):550-8. doi: 10.3109/10715762.2011.555483. Epub 2011 Feb 4.

PMID:
21291351
43.

Different mechanical loading protocols influence serum cartilage oligomeric matrix protein levels in young healthy humans.

Niehoff A, Kersting UG, Helling S, Dargel J, Maurer J, Thevis M, Brüggemann GP.

Eur J Appl Physiol. 2010 Oct;110(3):651-7. doi: 10.1007/s00421-010-1529-0. Epub 2010 Jun 11.

PMID:
20544356
44.

PTPN1 polymorphisms are associated with total and low-density lipoprotein cholesterol.

Bauer F, Onland-Moret NC, Niehoff AG, Elbers CC, Grobbee DE, Wijmenga C, van der Schouw YT.

Eur J Cardiovasc Prev Rehabil. 2010 Feb;17(1):28-34. doi: 10.1097/HJR.0b013e32832d30c4. Erratum in: Eur J Cardiovasc Prev Rehabil. 2010 Dec;17(6):737. Charlotte, Onland-Moret N [corrected to Onland-Moret, N Charlotte].

PMID:
20177231
45.

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization.

Belluoccio D, Grskovic I, Niehoff A, Schlötzer-Schrehardt U, Rosenbaum S, Etich J, Frie C, Pausch F, Moss SE, Pöschl E, Bateman JF, Brachvogel B.

J Bone Miner Res. 2010 Jan;25(1):141-53. doi: 10.1359/jbmr.090710.

46.

The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment.

de Boer TN, Huisman AM, Polak AA, Niehoff AG, van Rinsum AC, Saris D, Bijlsma JW, Lafeber FJ, Mastbergen SC.

Osteoarthritis Cartilage. 2009 Apr;17(4):482-8. doi: 10.1016/j.joca.2008.09.002. Epub 2008 Oct 15.

47.

No association of PTPN1 polymorphisms with macronutrient intake and measures of adiposity.

Bauer F, Onland-Moret NC, Niehoff AG, Elbers CC, Grobbee DE, Wijmenga C, van der Schouw YT.

Obesity (Silver Spring). 2008 Dec;16(12):2767-71. doi: 10.1038/oby.2008.426. Epub 2008 Oct 9.

48.

Stability changes after cryosurgery in long tubular bones in correlation to histological results: an animal trial.

Popken F, Michael JW, Zarghooni K, Sobottke R, Kasper HU, Blaecker D, Niehoff A, Emrich F, Eysel P.

Arch Orthop Trauma Surg. 2009 Jun;129(6):857-62. doi: 10.1007/s00402-008-0704-9. Epub 2008 Jul 24.

PMID:
18651109
49.

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

Blumbach K, Niehoff A, Paulsson M, Zaucke F.

Matrix Biol. 2008 May;27(4):306-18. doi: 10.1016/j.matbio.2007.11.007. Epub 2007 Dec 3.

PMID:
18191556
50.

Dynamic and static mechanical compression affects Akt phosphorylation in porcine patellofemoral joint cartilage.

Niehoff A, Offermann M, Dargel J, Schmidt A, Brüggemann GP, Bloch W.

J Orthop Res. 2008 May;26(5):616-23.

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