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Items: 43

1.

Environmental arginine controls multinuclear giant cell metabolism and formation.

Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O'Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G.

Nat Commun. 2020 Jan 22;11(1):431. doi: 10.1038/s41467-020-14285-1.

2.

Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis.

Göschl L, Preglej T, Boucheron N, Saferding V, Müller L, Platzer A, Hirahara K, Shih HY, Backlund J, Matthias P, Niederreiter B, Hladik A, Kugler M, Gualdoni GA, Scheinecker C, Knapp S, Seiser C, Holmdahl R, Tillmann K, Plasenzotti R, Podesser B, Aletaha D, Smolen JS, Karonitsch T, Steiner G, Ellmeier W, Bonelli M.

J Autoimmun. 2019 Dec 26:102379. doi: 10.1016/j.jaut.2019.102379. [Epub ahead of print]

PMID:
31883829
3.

IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.

Bonelli M, Dalwigk K, Platzer A, Olmos Calvo I, Hayer S, Niederreiter B, Holinka J, Sevelda F, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T.

Exp Mol Med. 2019 Jul 8;51(7):75. doi: 10.1038/s12276-019-0267-6.

4.

Multimodal [18 F]FDG PET/CT Is a Direct Readout for Inflammatory Bone Repair: A Longitudinal Study in TNFα Transgenic Mice.

Hayer S, Zeilinger M, Weiss V, Dumanic M, Seibt M, Niederreiter B, Shvets T, Pichler F, Wadsak W, Podesser BK, Helbich TH, Hacker M, Smolen JS, Redlich K, Mitterhauser M.

J Bone Miner Res. 2019 Sep;34(9):1632-1645. doi: 10.1002/jbmr.3748. Epub 2019 Jul 30.

5.

PI3K activity in dendritic cells exerts paradoxical effects during autoimmune inflammation.

Datler H, Vogel A, Kerndl M, Baumgartinger C, Musiejovsky L, Makivic N, Frech S, Niederreiter B, Haider T, Pühringer M, Brunner JS, Sharif O, Schabbauer G.

Mol Immunol. 2019 Jul;111:32-42. doi: 10.1016/j.molimm.2019.03.015. Epub 2019 Apr 5.

6.

FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes.

Brandstetter B, Dalwigk K, Platzer A, Niederreiter B, Kartnig F, Fischer A, Vladimer GI, Byrne RA, Sevelda F, Holinka J, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T.

Lab Invest. 2019 May;99(5):648-658. doi: 10.1038/s41374-018-0184-7. Epub 2019 Jan 24.

PMID:
30679758
7.

CCR6 controls autoimmune but not innate immunity-driven experimental arthritis.

Bonelli M, Puchner A, Göschl L, Hayer S, Niederreiter B, Steiner G, Tillmann K, Plasenzotti R, Podesser B, Georgel P, Smolen J, Scheinecker C, Blüml S.

J Cell Mol Med. 2018 Nov;22(11):5278-5285. doi: 10.1111/jcmm.13783. Epub 2018 Aug 22.

8.

The involvement of Toll-like receptor 9 in the pathogenesis of erosive autoimmune arthritis.

Fischer A, Abdollahi-Roodsaz S, Böhm C, Niederreiter B, Meyer B, Yau ACY, Lönnblom E, Joosten LAB, Koenders M, Lehmann CHK, Dudziak D, Krönke G, Holmdahl R, Steiner G.

J Cell Mol Med. 2018 Sep;22(9):4399-4409. doi: 10.1111/jcmm.13735. Epub 2018 Jul 11.

9.

Non-classical monocytes as mediators of tissue destruction in arthritis.

Puchner A, Saferding V, Bonelli M, Mikami Y, Hofmann M, Brunner JS, Caldera M, Goncalves-Alves E, Binder NB, Fischer A, Simader E, Steiner CW, Leiss H, Hayer S, Niederreiter B, Karonitsch T, Koenders MI, Podesser BK, O'Shea JJ, Menche J, Smolen JS, Redlich K, Blüml S.

Ann Rheum Dis. 2018 Oct;77(10):1490-1497. doi: 10.1136/annrheumdis-2018-213250. Epub 2018 Jun 29.

10.

mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation.

Karonitsch T, Kandasamy RK, Kartnig F, Herdy B, Dalwigk K, Niederreiter B, Holinka J, Sevelda F, Windhager R, Bilban M, Weichhart T, Säemann M, Pap T, Steiner G, Smolen JS, Kiener HP, Superti-Furga G.

Cell Rep. 2018 May 15;23(7):2157-2167. doi: 10.1016/j.celrep.2018.04.044.

11.

Targeted inhibition of Janus kinases abates interfon gamma-induced invasive behaviour of fibroblast-like synoviocytes.

Karonitsch T, Beckmann D, Dalwigk K, Niederreiter B, Studenic P, Byrne RA, Holinka J, Sevelda F, Korb-Pap A, Steiner G, Smolen JS, Pap T, Kiener HP.

Rheumatology (Oxford). 2018 Mar 1;57(3):572-577. doi: 10.1093/rheumatology/kex426.

PMID:
29228301
12.

Therapeutic Modulation of Plasmacytoid Dendritic Cells in Experimental Arthritis.

Nehmar R, Alsaleh G, Voisin B, Flacher V, Mariotte A, Saferding V, Puchner A, Niederreiter B, Vandamme T, Schabbauer G, Kastner P, Chan S, Kirstetter P, Holcmann M, Mueller C, Sibilia J, Bahram S, Blüml S, Georgel P.

Arthritis Rheumatol. 2017 Nov;69(11):2124-2135. doi: 10.1002/art.40225.

13.

MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.

Saferding V, Puchner A, Goncalves-Alves E, Hofmann M, Bonelli M, Brunner JS, Sahin E, Niederreiter B, Hayer S, Kiener HP, Einwallner E, Nehmar R, Carapito R, Georgel P, Koenders MI, Boldin M, Schabbauer G, Kurowska-Stolarska M, Steiner G, Smolen JS, Redlich K, Blüml S.

J Autoimmun. 2017 Aug;82:74-84. doi: 10.1016/j.jaut.2017.05.006. Epub 2017 May 22.

PMID:
28545737
14.

Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury.

Kral-Pointner JB, Schrottmaier WC, Horvath V, Datler H, Hell L, Ay C, Niederreiter B, Jilma B, Schmid JA, Assinger A, Mackman N, Knapp S, Schabbauer G.

J Thromb Haemost. 2017 Aug;15(8):1625-1639. doi: 10.1111/jth.13737. Epub 2017 Jun 20.

15.

Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression.

Linke M, Pham HT, Katholnig K, Schnöller T, Miller A, Demel F, Schütz B, Rosner M, Kovacic B, Sukhbaatar N, Niederreiter B, Blüml S, Kuess P, Sexl V, Müller M, Mikula M, Weckwerth W, Haschemi A, Susani M, Hengstschläger M, Gambello MJ, Weichhart T.

Nat Immunol. 2017 Mar;18(3):293-302. doi: 10.1038/ni.3655. Epub 2017 Jan 16.

16.

Cartilage damage and bone erosion are more prominent determinants of functional impairment in longstanding experimental arthritis than synovial inflammation.

Hayer S, Bauer G, Willburger M, Sinn K, Alasti F, Plasenzotti R, Shvets T, Niederreiter B, Aschauer C, Steiner G, Podesser BK, Smolen JS, Redlich K.

Dis Model Mech. 2016 Nov 1;9(11):1329-1338. Epub 2016 Sep 16.

17.

Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis.

Blüml S, Sahin E, Saferding V, Goncalves-Alves E, Hainzl E, Niederreiter B, Hladik A, Lohmeyer T, Brunner JS, Bonelli M, Koenders MI, van den Berg WB, Superti-Furga G, Smolen JS, Schabbauer G, Redlich K.

Arthritis Res Ther. 2015 Aug 26;17:230. doi: 10.1186/s13075-015-0742-y.

18.

Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.

Sahin E, Brunner JS, Kral JB, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal AM, Krönke G, Blüml S, Schabbauer G.

J Immunol. 2015 Sep 15;195(6):2560-70. doi: 10.4049/jimmunol.1402511. Epub 2015 Aug 5.

19.

The MAPK-Activated Kinase MK2 Attenuates Dendritic Cell-Mediated Th1 Differentiation and Autoimmune Encephalomyelitis.

Soukup K, Halfmann A, Le Bras M, Sahin E, Vittori S, Poyer F, Schuh C, Luger R, Niederreiter B, Haider T, Stoiber D, Blüml S, Schabbauer G, Kotlyarov A, Gaestel M, Felzmann T, Dohnal AM.

J Immunol. 2015 Jul 15;195(2):541-52. doi: 10.4049/jimmunol.1401663. Epub 2015 Jun 15.

20.

Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease.

Hadaschik EN, Wei X, Leiss H, Heckmann B, Niederreiter B, Steiner G, Ulrich W, Enk AH, Smolen JS, Stummvoll GH.

Arthritis Res Ther. 2015 Feb 23;17:35. doi: 10.1186/s13075-015-0538-0.

21.

CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis.

Karpus ON, Kiener HP, Niederreiter B, Yilmaz-Elis AS, van der Kaa J, Ramaglia V, Arens R, Smolen JS, Botto M, Tak PP, Verbeek JS, Hamann J.

Arthritis Res Ther. 2015 Jan 17;17:6. doi: 10.1186/s13075-015-0518-4.

22.

FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.

Wixler V, Cromme C, Retser E, Meyer LH, Smyth N, Mühlenberg K, Korb-Pap A, Koers-Wunrau C, Sotsios Y, Bassel-Duby R, Baeten D, Tak PP, Niederreiter B, Redlich K, Bertrand J, Skryabin BV, Ludwig S, Pap T.

Ann Rheum Dis. 2015 Dec;74(12):2216-23. doi: 10.1136/annrheumdis-2013-205061. Epub 2014 Aug 14.

PMID:
25125695
23.

Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells.

Blüml S, Friedrich M, Lohmeyer T, Sahin E, Saferding V, Brunner J, Puchner A, Mandl P, Niederreiter B, Smolen JS, Schabbauer G, Redlich K.

Ann Rheum Dis. 2015 Jan;74(1):227-33. doi: 10.1136/annrheumdis-2013-203486. Epub 2013 Sep 27.

PMID:
24078675
24.

Interphalangeal Osteoarthritis Radiographic Simplified (iOARS) score: a radiographic method to detect osteoarthritis of the interphalangeal finger joints based on its histopathological alterations.

Sunk IG, Amoyo-Minar L, Stamm T, Haider S, Niederreiter B, Supp G, Soleiman A, Kainberger F, Smolen JS, Bobacz K.

Ann Rheum Dis. 2014 Nov;73(11):1983-9. doi: 10.1136/annrheumdis-2012-203117. Epub 2013 Jul 29.

PMID:
23897771
25.

Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation.

Leiss H, Niederreiter B, Bandur T, Schwarzecker B, Blüml S, Steiner G, Ulrich W, Smolen JS, Stummvoll GH.

Lupus. 2013 Jul;22(8):778-92. doi: 10.1177/0961203313492869.

PMID:
23817510
26.

Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis.

Binder NB, Puchner A, Niederreiter B, Hayer S, Leiss H, Blüml S, Kreindl R, Smolen JS, Redlich K.

Arthritis Rheum. 2013 Mar;65(3):608-17. doi: 10.1002/art.37797.

27.

Abatacept (CTLA-4IG) treatment reduces the migratory capacity of monocytes in patients with rheumatoid arthritis.

Bonelli M, Ferner E, Göschl L, Blüml S, Hladik A, Karonitsch T, Kiener HP, Byrne R, Niederreiter B, Steiner CW, Rath E, Bergmann M, Smolen JS, Scheinecker C.

Arthritis Rheum. 2013 Mar;65(3):599-607. doi: 10.1002/art.37787.

28.

The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats.

Hoffmann MH, Bruns H, Bäckdahl L, Neregård P, Niederreiter B, Herrmann M, Catrina AI, Agerberth B, Holmdahl R.

Ann Rheum Dis. 2013 Jul;72(7):1239-48. doi: 10.1136/annrheumdis-2012-202218. Epub 2012 Nov 21.

PMID:
23172753
29.

Cell death and cytokine production induced by autoimmunogenic hydrocarbon oils.

Herman S, Kny A, Schorn C, Pfatschbacher J, Niederreiter B, Herrmann M, Holmdahl R, Steiner G, Hoffmann MH.

Autoimmunity. 2012 Dec;45(8):602-11. doi: 10.3109/08916934.2012.719948. Epub 2012 Sep 17.

PMID:
22917079
30.

Histopathological correlation supports the use of x-rays in the diagnosis of hand osteoarthritis.

Sunk IG, Amoyo-Minar L, Niederreiter B, Soleiman A, Kainberger F, Smolen JS, Bobacz K.

Ann Rheum Dis. 2013 Apr;72(4):572-7. doi: 10.1136/annrheumdis-2011-200925. Epub 2012 May 12.

PMID:
22580584
31.

A dynamic real time in vivo and static ex vivo analysis of granulomonocytic cell migration in the collagen-induced arthritis model.

Byrne R, Rath E, Hladik A, Niederreiter B, Bonelli M, Frantal S, Smolen JS, Scheinecker C.

PLoS One. 2012;7(4):e35194. doi: 10.1371/journal.pone.0035194. Epub 2012 Apr 18.

32.

Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis.

Korb-Pap A, Stratis A, Mühlenberg K, Niederreiter B, Hayer S, Echtermeyer F, Stange R, Zwerina J, Pap T, Pavenstädt H, Schett G, Smolen JS, Redlich K.

Ann Rheum Dis. 2012 Jun;71(6):1004-11. doi: 10.1136/annrheumdis-2011-200386. Epub 2012 Jan 18.

PMID:
22258493
33.

Effects of 18β-Glycyrrhetinic acid in hTNFtg mice - a model of rheumatoid arthritis.

Puchner A, Hayer S, Niederreiter B, Hladik A, Blueml S, Bonelli M, Scheinecker C, Smolen J, Redlich K.

Wien Klin Wochenschr. 2012 Mar;124(5-6):170-6. doi: 10.1007/s00508-011-0103-z. Epub 2012 Jan 3.

PMID:
22210441
34.

Nucleic acid-stimulated antigen-presenting cells trigger T cells to induce disease in a rat transfer model of inflammatory arthritis.

Hoffmann MH, Skriner K, Herman S, Baumann C, Steiner CW, Ospelt C, Meyer B, Gleiss A, Pfatschbacher J, Niederreiter B, Tuncel J, Zanoni G, Steiner G.

J Autoimmun. 2011 May;36(3-4):288-300. doi: 10.1016/j.jaut.2011.02.007. Epub 2011 Mar 24.

PMID:
21439786
35.

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice.

Blüml S, Bonelli M, Niederreiter B, Puchner A, Mayr G, Hayer S, Koenders MI, van den Berg WB, Smolen J, Redlich K.

Arthritis Rheum. 2011 May;63(5):1281-8. doi: 10.1002/art.30281.

36.

Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis.

Cejka D, Hayer S, Niederreiter B, Sieghart W, Fuereder T, Zwerina J, Schett G.

Arthritis Rheum. 2010 Aug;62(8):2294-302. doi: 10.1002/art.27504.

37.

Interleukin 6 is not a crucial regulator in an animal model of tumour necrosis factor-mediated bilateral sacroiliitis.

Hayer S, Niederreiter B, Nagelreiter I, Smolen J, Redlich K.

Ann Rheum Dis. 2010 Jul;69(7):1403-6. doi: 10.1136/ard.2010.129148. Epub 2010 May 24.

PMID:
20498200
38.

Gait changes precede overt arthritis and strongly correlate with symptoms and histopathological events in pristane-induced arthritis.

Hoffmann MH, Hopf R, Niederreiter B, Redl H, Smolen JS, Steiner G.

Arthritis Res Ther. 2010;12(2):R41. doi: 10.1186/ar2950. Epub 2010 Mar 11.

39.

Antiinflammatory effects of tumor necrosis factor on hematopoietic cells in a murine model of erosive arthritis.

Blüml S, Binder NB, Niederreiter B, Polzer K, Hayer S, Tauber S, Schett G, Scheinecker C, Kollias G, Selzer E, Bilban M, Smolen JS, Superti-Furga G, Redlich K.

Arthritis Rheum. 2010 Jun;62(6):1608-19. doi: 10.1002/art.27399.

40.

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.

Kiener HP, Watts GF, Cui Y, Wright J, Thornhill TS, Sköld M, Behar SM, Niederreiter B, Lu J, Cernadas M, Coyle AJ, Sims GP, Smolen J, Warman ML, Brenner MB, Lee DM.

Arthritis Rheum. 2010 Mar;62(3):742-52. doi: 10.1002/art.27285.

41.

Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes.

Kiener HP, Niederreiter B, Lee DM, Jimenez-Boj E, Smolen JS, Brenner MB.

Arthritis Rheum. 2009 May;60(5):1305-10. doi: 10.1002/art.24453.

42.

Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.

Binder NB, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig TM, Mack M, Erben RG, Smolen JS, Redlich K.

Nat Med. 2009 Apr;15(4):417-24. doi: 10.1038/nm.1945. Epub 2009 Mar 29.

PMID:
19330010
43.

[Platelet aggregation with SIN 1: comparison with isosorbide-5-mononitrate and acetylsalicylic acid].

Gerzer R, Karrenbrock B, Niederreiter B, Heim JM, Drummer C.

Z Kardiol. 1991;80 Suppl 5:9-11. German.

PMID:
1776339

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