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Items: 1 to 50 of 73

1.

Subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize in zebrafish sensory hair cells.

Pacentine IV, Nicolson T.

PLoS Genet. 2019 Feb 6;15(2):e1007635. doi: 10.1371/journal.pgen.1007635. eCollection 2019 Feb.

2.

Zebrafish: from genes and neurons to circuits, behavior and disease.

Chandrasekhar A, Guo S, Masai I, Nicolson T, Wu CF.

J Neurogenet. 2017 Sep;31(3):59-60. doi: 10.1080/01677063.2017.1359589. No abstract available.

PMID:
28868983
3.

The genetics of hair-cell function in zebrafish.

Nicolson T.

J Neurogenet. 2017 Sep;31(3):102-112. doi: 10.1080/01677063.2017.1342246. Epub 2017 Jul 13. Review.

4.

Enlargement of Ribbons in Zebrafish Hair Cells Increases Calcium Currents But Disrupts Afferent Spontaneous Activity and Timing of Stimulus Onset.

Sheets L, He XJ, Olt J, Schreck M, Petralia RS, Wang YX, Zhang Q, Beirl A, Nicolson T, Marcotti W, Trapani JG, Kindt KS.

J Neurosci. 2017 Jun 28;37(26):6299-6313. doi: 10.1523/JNEUROSCI.2878-16.2017. Epub 2017 May 25.

5.

Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).

Erickson T, Morgan CP, Olt J, Hardy K, Busch-Nentwich E, Maeda R, Clemens R, Krey JF, Nechiporuk A, Barr-Gillespie PG, Marcotti W, Nicolson T.

Elife. 2017 May 23;6. pii: e28474. doi: 10.7554/eLife.28474.

6.

Functional Analysis of the Transmembrane and Cytoplasmic Domains of Pcdh15a in Zebrafish Hair Cells.

Maeda R, Pacentine IV, Erickson T, Nicolson T.

J Neurosci. 2017 Mar 22;37(12):3231-3245. doi: 10.1523/JNEUROSCI.2216-16.2017. Epub 2017 Feb 20.

7.

Cell type-specific transcriptomic analysis by thiouracil tagging in zebrafish.

Erickson T, Nicolson T.

Methods Cell Biol. 2016;135:309-28. doi: 10.1016/bs.mcb.2016.04.009. Epub 2016 May 4.

PMID:
27443933
8.

Dopamine Modulates the Activity of Sensory Hair Cells.

Toro C, Trapani JG, Pacentine I, Maeda R, Sheets L, Mo W, Nicolson T.

J Neurosci. 2015 Dec 16;35(50):16494-503. doi: 10.1523/JNEUROSCI.1691-15.2015.

9.

Identification of sensory hair-cell transcripts by thiouracil-tagging in zebrafish.

Erickson T, Nicolson T.

BMC Genomics. 2015 Oct 23;16:842. doi: 10.1186/s12864-015-2072-5.

10.

It takes two.

Nicolson T.

Elife. 2015 Oct 6;4. doi: 10.7554/eLife.11399.

11.

Ribbon synapses in zebrafish hair cells.

Nicolson T.

Hear Res. 2015 Dec;330(Pt B):170-7. doi: 10.1016/j.heares.2015.04.003. Epub 2015 Apr 25. Review.

12.

Expression of drug transporters in human kidney: impact of sex, age, and ethnicity.

Joseph S, Nicolson TJ, Hammons G, Word B, Green-Knox B, Lyn-Cook B.

Biol Sex Differ. 2015 Mar 2;6:4. doi: 10.1186/s13293-015-0020-3. eCollection 2015.

13.

Characterization of Ribeye subunits in zebrafish hair cells reveals that exogenous Ribeye B-domain and CtBP1 localize to the basal ends of synaptic ribbons.

Sheets L, Hagen MW, Nicolson T.

PLoS One. 2014 Sep 10;9(9):e107256. doi: 10.1371/journal.pone.0107256. eCollection 2014.

14.

Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2.

Maeda R, Kindt KS, Mo W, Morgan CP, Erickson T, Zhao H, Clemens-Grisham R, Barr-Gillespie PG, Nicolson T.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12907-12. doi: 10.1073/pnas.1402152111. Epub 2014 Aug 11.

15.

Preclinical safety and efficacy of an anti-HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor.

Wolstein O, Boyd M, Millington M, Impey H, Boyer J, Howe A, Delebecque F, Cornetta K, Rothe M, Baum C, Nicolson T, Koldej R, Zhang J, Keech N, Camba Colón J, Breton L, Bartlett J, An DS, Chen IS, Burke B, Symonds GP.

Mol Ther Methods Clin Dev. 2014 Feb 12;1:11. doi: 10.1038/mtm.2013.11. eCollection 2014.

16.

Who needs tip links? Backwards transduction by hair cells.

Barr-Gillespie PG, Nicolson T.

J Gen Physiol. 2013 Nov;142(5):481-6. doi: 10.1085/jgp.201311111. Epub 2013 Oct 14. No abstract available.

17.

Mutations in ap1b1 cause mistargeting of the Na(+)/K(+)-ATPase pump in sensory hair cells.

Clemens Grisham R, Kindt K, Finger-Baier K, Schmid B, Nicolson T.

PLoS One. 2013 Apr 12;8(4):e60866. doi: 10.1371/journal.pone.0060866. Print 2013.

18.

Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond.

Kalueff AV, Gebhardt M, Stewart AM, Cachat JM, Brimmer M, Chawla JS, Craddock C, Kyzar EJ, Roth A, Landsman S, Gaikwad S, Robinson K, Baatrup E, Tierney K, Shamchuk A, Norton W, Miller N, Nicolson T, Braubach O, Gilman CP, Pittman J, Rosemberg DB, Gerlai R, Echevarria D, Lamb E, Neuhauss SC, Weng W, Bally-Cuif L, Schneider H; Zebrafish Neuroscience Research Consortium.

Zebrafish. 2013 Mar;10(1):70-86. doi: 10.1089/zeb.2012.0861. Review.

19.

Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells.

Sheets L, Kindt KS, Nicolson T.

J Neurosci. 2012 Nov 28;32(48):17273-86. doi: 10.1523/JNEUROSCI.3005-12.2012.

20.

Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing.

Obholzer N, Swinburne IA, Schwab E, Nechiporuk AV, Nicolson T, Megason SG.

Development. 2012 Nov;139(22):4280-90. doi: 10.1242/dev.083931. Epub 2012 Oct 10.

21.

The Usher gene cadherin 23 is expressed in the zebrafish brain and a subset of retinal amacrine cells.

Glover G, Mueller KP, Söllner C, Neuhauss SC, Nicolson T.

Mol Vis. 2012;18:2309-22. Epub 2012 Sep 5.

22.

Kinocilia mediate mechanosensitivity in developing zebrafish hair cells.

Kindt KS, Finch G, Nicolson T.

Dev Cell. 2012 Aug 14;23(2):329-41. doi: 10.1016/j.devcel.2012.05.022.

23.

Rabconnectin3α promotes stable activity of the H+ pump on synaptic vesicles in hair cells.

Einhorn Z, Trapani JG, Liu Q, Nicolson T.

J Neurosci. 2012 Aug 8;32(32):11144-56. doi: 10.1523/JNEUROSCI.1705-12.2012.

24.

Both pre- and postsynaptic activity of Nsf prevents degeneration of hair-cell synapses.

Mo W, Nicolson T.

PLoS One. 2011;6(11):e27146. doi: 10.1371/journal.pone.0027146. Epub 2011 Nov 3.

25.

Gene therapy: therapeutic applications and relevance to pathology.

Both G, Alexander I, Fletcher S, Nicolson TJ, Rasko JE, Wilton SD, Symonds G.

Pathology. 2011 Oct;43(6):642-56. doi: 10.1097/PAT.0b013e32834b1dad. Review.

PMID:
21897331
26.

Angiographic embolisation of pelvic ring injuries. Treatment algorithm and review of the literature.

Karadimas EJ, Nicolson T, Kakagia DD, Matthews SJ, Richards PJ, Giannoudis PV.

Int Orthop. 2011 Sep;35(9):1381-90. doi: 10.1007/s00264-011-1271-1. Epub 2011 May 17. Review.

27.

Ribeye is required for presynaptic Ca(V)1.3a channel localization and afferent innervation of sensory hair cells.

Sheets L, Trapani JG, Mo W, Obholzer N, Nicolson T.

Development. 2011 Apr;138(7):1309-19. doi: 10.1242/dev.059451. Epub 2011 Feb 24.

28.

Mechanism of spontaneous activity in afferent neurons of the zebrafish lateral-line organ.

Trapani JG, Nicolson T.

J Neurosci. 2011 Feb 2;31(5):1614-23. doi: 10.1523/JNEUROSCI.3369-10.2011.

29.

Physiological recordings from zebrafish lateral-line hair cells and afferent neurons.

Trapani JG, Nicolson T.

Methods Cell Biol. 2010;100:219-31. doi: 10.1016/B978-0-12-384892-5.00008-6.

PMID:
21111219
30.

Quantification of vestibular-induced eye movements in zebrafish larvae.

Mo W, Chen F, Nechiporuk A, Nicolson T.

BMC Neurosci. 2010 Sep 3;11:110. doi: 10.1186/1471-2202-11-110.

31.

In vivo evidence for transdifferentiation of peripheral neurons.

Wright MA, Mo W, Nicolson T, Ribera AB.

Development. 2010 Sep;137(18):3047-56. doi: 10.1242/dev.052696. Epub 2010 Aug 4.

32.

Gender differences in drug toxicity.

Nicolson TJ, Mellor HR, Roberts RR.

Trends Pharmacol Sci. 2010 Mar;31(3):108-14. doi: 10.1016/j.tips.2009.12.001. Epub 2010 Feb 1. Review.

PMID:
20117848
33.

Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis.

Vinkenborg JL, Nicolson TJ, Bellomo EA, Koay MS, Rutter GA, Merkx M.

Nat Methods. 2009 Oct;6(10):737-40. doi: 10.1038/nmeth.1368. Epub 2009 Aug 30.

34.

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

Diabetes. 2009 Sep;58(9):2070-83. doi: 10.2337/db09-0551. Epub 2009 Jun 19.

35.

Synaptojanin1 is required for temporal fidelity of synaptic transmission in hair cells.

Trapani JG, Obholzer N, Mo W, Brockerhoff SE, Nicolson T.

PLoS Genet. 2009 May;5(5):e1000480. doi: 10.1371/journal.pgen.1000480. Epub 2009 May 8.

36.

A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.

Tarasov AI, Nicolson TJ, Riveline JP, Taneja TK, Baldwin SA, Baldwin JM, Charpentier G, Gautier JF, Froguel P, Vaxillaire M, Rutter GA.

Diabetes. 2008 Jun;57(6):1595-604. doi: 10.2337/db07-1547. Epub 2008 Mar 17.

37.

Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells.

Obholzer N, Wolfson S, Trapani JG, Mo W, Nechiporuk A, Busch-Nentwich E, Seiler C, Sidi S, Söllner C, Duncan RN, Boehland A, Nicolson T.

J Neurosci. 2008 Feb 27;28(9):2110-8. doi: 10.1523/JNEUROSCI.5230-07.2008.

38.

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.

Blagoveshchenskaya A, Cheong FY, Rohde HM, Glover G, Knödler A, Nicolson T, Boehmelt G, Mayinger P.

J Cell Biol. 2008 Feb 25;180(4):803-12. doi: 10.1083/jcb.200708109.

39.

Prostaglandin E2 sensitizes primary sensory neurons to histamine.

Nicolson TA, Foster AF, Bevan S, Richards CD.

Neuroscience. 2007 Nov 30;150(1):22-30. Epub 2007 Sep 14.

PMID:
17945428
40.

Large-scale mapping of mutations affecting zebrafish development.

Geisler R, Rauch GJ, Geiger-Rudolph S, Albrecht A, van Bebber F, Berger A, Busch-Nentwich E, Dahm R, Dekens MP, Dooley C, Elli AF, Gehring I, Geiger H, Geisler M, Glaser S, Holley S, Huber M, Kerr A, Kirn A, Knirsch M, Konantz M, Küchler AM, Maderspacher F, Neuhauss SC, Nicolson T, Ober EA, Praeg E, Ray R, Rentzsch B, Rick JM, Rief E, Schauerte HE, Schepp CP, Schönberger U, Schonthaler HB, Seiler C, Sidi S, Söllner C, Wehner A, Weiler C, Nüsslein-Volhard C.

BMC Genomics. 2007 Jan 9;8:11.

41.

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis.

Varadi A, Grant A, McCormack M, Nicolson T, Magistri M, Mitchell KJ, Halestrap AP, Yuan H, Schwappach B, Rutter GA.

Diabetologia. 2006 Jul;49(7):1567-77. Epub 2006 May 12.

PMID:
16752175
42.

The genetics of hearing and balance in zebrafish.

Nicolson T.

Annu Rev Genet. 2005;39:9-22. Review.

PMID:
16285850
43.

Fishing for key players in mechanotransduction.

Nicolson T.

Trends Neurosci. 2005 Mar;28(3):140-4. Review.

PMID:
15749167
44.

Duplicated genes with split functions: independent roles of protocadherin15 orthologues in zebrafish hearing and vision.

Seiler C, Finger-Baier KC, Rinner O, Makhankov YV, Schwarz H, Neuhauss SC, Nicolson T.

Development. 2005 Feb;132(3):615-23. Epub 2005 Jan 5.

45.

Molecules and mechanisms of mechanotransduction.

Goodman MB, Lumpkin EA, Ricci A, Tracey WD, Kernan M, Nicolson T.

J Neurosci. 2004 Oct 20;24(42):9220-2. Review. No abstract available.

46.

Mutated otopetrin 1 affects the genesis of otoliths and the localization of Starmaker in zebrafish.

Söllner C, Schwarz H, Geisler R, Nicolson T.

Dev Genes Evol. 2004 Dec;214(12):582-90. Epub 2004 Oct 5.

PMID:
15480759
47.

Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish.

Seiler C, Ben-David O, Sidi S, Hendrich O, Rusch A, Burnside B, Avraham KB, Nicolson T.

Dev Biol. 2004 Aug 15;272(2):328-38.

PMID:
15282151
48.

gemini encodes a zebrafish L-type calcium channel that localizes at sensory hair cell ribbon synapses.

Sidi S, Busch-Nentwich E, Friedrich R, Schoenberger U, Nicolson T.

J Neurosci. 2004 Apr 28;24(17):4213-23.

49.

Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells.

Söllner C, Rauch GJ, Siemens J, Geisler R, Schuster SC, Müller U, Nicolson T; Tübingen 2000 Screen Consortium.

Nature. 2004 Apr 29;428(6986):955-9. Epub 2004 Mar 31.

50.

A family of acid-sensing ion channels from the zebrafish: widespread expression in the central nervous system suggests a conserved role in neuronal communication.

Paukert M, Sidi S, Russell C, Siba M, Wilson SW, Nicolson T, Gründer S.

J Biol Chem. 2004 Apr 30;279(18):18783-91. Epub 2004 Feb 16.

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