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Editorial: tailoring mycophenolate mofetil rescue therapy for success in autoimmune hepatitis-authors' reply.

Nicoll AJ, Roberts SK, Strasser SI; Tapestry Investigators of the Australian Liver Association Clinical Research Network.

Aliment Pharmacol Ther. 2019 Jun;49(11):1450-1451. doi: 10.1111/apt.15276. No abstract available.


Editorial: post-operative elevation of liver enzymes and modern volatile anaesthetics-guilty as charged? Authors' reply.

Nicoll A, Sood S, Bishop B, Njoku D.

Aliment Pharmacol Ther. 2019 May;49(9):1246-1247. doi: 10.1111/apt.15237. No abstract available.


Beneficial response to mycophenolate mofetil by patients with autoimmune hepatitis who have failed standard therapy, is predicted by older age and lower immunoglobulin G and INR levels.

Nicoll AJ, Roberts SK, Lim R, Mitchell J, Weltman M, George J, Wigg A, Stuart K, Gow P, MacQuillan G, Tse E, Levy M, Sood S, Zekry A, Cheng W, Mitchell J, Skoien R, Sievert W, Strasser SI, McCaughan GW; ALA Clinical Research Network, Gastroenterological Society of Australia.

Aliment Pharmacol Ther. 2019 May;49(10):1314-1322. doi: 10.1111/apt.15248. Epub 2019 Apr 11.


A prospective study of the incidence of drug-induced liver injury by the modern volatile anaesthetics sevoflurane and desflurane.

Bishop B, Hannah N, Doyle A, Amico F, Hockey B, Moore D, Sood S, Gorelik A, Liew D, Njoku D, Nicoll A.

Aliment Pharmacol Ther. 2019 Apr;49(7):940-951. doi: 10.1111/apt.15168. Epub 2019 Feb 13.


Effectiveness of a professional development training program in increasing knowledge of mental health clinicians specializing in early psychosis.

Macneil C, Foster F, Nicoll A, Monfries R, Coulson L, Osman H, Grainger M, Cotton S.

Early Interv Psychiatry. 2019 Jan 21. doi: 10.1111/eip.12785. [Epub ahead of print]


Treatment choice for early-stage hepatocellular carcinoma in real-world practice: impact of treatment stage migration to transarterial chemoembolization and treatment response on survival.

Roberts SK, Gazzola A, Lubel J, Gow P, Bell S, Nicoll A, Dev A, Fink MA, Sood S, Knight V, Hong T, Paul E, Mishra G, Majeed A, Kemp W; Melbourne Liver Group.

Scand J Gastroenterol. 2018 Oct - Nov;53(10-11):1368-1375. doi: 10.1080/00365521.2018.1517277. Epub 2018 Nov 5.


Surveillance improves survival of patients with hepatocellular carcinoma: a prospective population-based study.

Hong TP, Gow PJ, Fink M, Dev A, Roberts SK, Nicoll A, Lubel JS, Kronborg I, Arachchi N, Ryan M, Kemp WW, Knight V, Sundararajan V, Desmond P, Thompson AJ, Bell SJ.

Med J Aust. 2018 Oct 15;209(8):348-354.


Improving the sustainability of hospital-based interventions: a study protocol for a systematic review.

Cowie J, Campbell P, Dimova E, Nicoll A, Duncan EAS.

BMJ Open. 2018 Sep 5;8(9):e025069. doi: 10.1136/bmjopen-2018-025069.


Perinatal outcomes following mid trimester detection of isolated short foetal femur length.

Smith M, Nicoll A.

J Obstet Gynaecol. 2018 Jul;38(5):727. doi: 10.1080/01443615.2018.1444408.


Depression, fatigue and neurocognitive deficits in chronic hepatitis C.

Yeoh SW, Holmes ACN, Saling MM, Everall IP, Nicoll AJ.

Hepatol Int. 2018 Jul;12(4):294-304. doi: 10.1007/s12072-018-9879-5. Epub 2018 Jun 21. Review.


Non-alcoholic fatty liver disease patients attending two metropolitan hospitals in Melbourne, Australia: high risk status and low prevalence.

George ES, Roberts SK, Nicoll AJ, Reddy A, Paris T, Itsiopoulos C, Tierney AC.

Intern Med J. 2018 Nov;48(11):1369-1376. doi: 10.1111/imj.13973.


Reply to: Intrinsic Toxicity of Antibodies to the Globular Domain of the Prion Protein.

Purro SA, Mead S, Khalili-Shirazi A, Nicoll AJ, Collinge J.

Biol Psychiatry. 2018 Oct 1;84(7):e53-e54. doi: 10.1016/j.biopsych.2018.04.002. Epub 2018 Apr 12. No abstract available.


Liver stiffness measurement in the primary care setting detects high rates of advanced fibrosis and predicts liver-related events in hepatitis C.

Bloom S, Kemp W, Nicoll A, Roberts SK, Gow P, Dev A, Bell S, Sood S, Kronborg I, Knight V, Lewis D, Lubel J.

J Hepatol. 2018 Sep;69(3):575-583. doi: 10.1016/j.jhep.2018.04.013. Epub 2018 Apr 28.


Practical Dietary Recommendations for the Prevention and Management of Nonalcoholic Fatty Liver Disease in Adults.

George ES, Forsyth A, Itsiopoulos C, Nicoll AJ, Ryan M, Sood S, Roberts SK, Tierney AC.

Adv Nutr. 2018 Jan 1;9(1):30-40. doi: 10.1093/advances/nmx007. Review.


Prion Protein as a Toxic Acceptor of Amyloid-β Oligomers.

Purro SA, Nicoll AJ, Collinge J.

Biol Psychiatry. 2018 Feb 15;83(4):358-368. doi: 10.1016/j.biopsych.2017.11.020. Epub 2017 Nov 21. Review.


Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial.

Ong SY, Gurrin LC, Dolling L, Dixon J, Nicoll AJ, Wolthuizen M, Wood EM, Anderson GJ, Ramm GA, Allen KJ, Olynyk JK, Crawford D, Ramm LE, Gow P, Durrant S, Powell LW, Delatycki MB.

Lancet Haematol. 2017 Dec;4(12):e607-e614. doi: 10.1016/S2352-3026(17)30214-4.


Soluble Aβ aggregates can inhibit prion propagation.

Sarell CJ, Quarterman E, Yip DC, Terry C, Nicoll AJ, Wadsworth JDF, Farrow MA, Walsh DM, Collinge J.

Open Biol. 2017 Nov;7(11). pii: 170158. doi: 10.1098/rsob.170158.


G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.

Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, Calvo A, Chio A, Houlden H, Polke JM, Ismail MA, Stephens CE, Vo T, Farahat AA, Wilson WD, Boykin DW, Zetterberg H, Partridge L, Wray S, Parkinson G, Neidle S, Patani R, Fratta P, Isaacs AM.

EMBO Mol Med. 2018 Jan;10(1):22-31. doi: 10.15252/emmm.201707850.


Efficacy and Safety of Mycophenolate Mofetil in Patients With Autoimmune Hepatitis and Suboptimal Outcomes After Standard Therapy.

Roberts SK, Lim R, Strasser S, Nicoll A, Gazzola A, Mitchell J, Siow W, Khoo T, Hamarneh Z, Weltman M, Gow P, Janko N, Tse E, Mishra G, Cheng EH, Levy M, Cheng W, Sood S, Skoien R, Mitchell J, Zekry A, George J, MacQuillan G, Wigg A, Stuart K, Sievert W, McCaughan G; ALA Clinical Research Network.

Clin Gastroenterol Hepatol. 2018 Feb;16(2):268-277. doi: 10.1016/j.cgh.2017.09.063. Epub 2017 Oct 16.


Variability of Liver Shear Wave Measurements Using a New Ultrasound Elastographic Technique.

Nadebaum DP, Nicoll AJ, Sood S, Gorelik A, Gibson RN.

J Ultrasound Med. 2018 Mar;37(3):647-656. doi: 10.1002/jum.14375. Epub 2017 Sep 29.



Haridy J, Sood S, Nicoll A.

Clin Gastroenterol Hepatol. 2018 Jan;16(1):149-150. doi: 10.1016/j.cgh.2017.08.051. Epub 2017 Sep 8. No abstract available.


The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson's disease.

Masterson-Algar P, Burton CR, Brady MC, Nicoll A, Clarke CE, Rick C, Hughes M, Au P, Smith CH, Sackley CM.

Trials. 2017 Aug 29;18(1):397. doi: 10.1186/s13063-017-2130-1.


Evaluation of a professional development training programme for mental health clinicians specializing in early psychosis.

Macneil C, Foster F, Nicoll A, Osman H, Monfries R, Cotton S.

Early Interv Psychiatry. 2018 Jun;12(3):483-490. doi: 10.1111/eip.12424. Epub 2017 Jul 26.


Methotrexate Therapy for Autoimmune Hepatitis.

Haridy J, Nicoll A, Sood S.

Clin Gastroenterol Hepatol. 2018 Feb;16(2):288-289. doi: 10.1016/j.cgh.2017.07.003. Epub 2017 Jul 12. No abstract available.


Delivery of alcohol brief interventions in community-based youth work settings: exploring feasibility and acceptability in a qualitative study.

Stead M, Parkes T, Nicoll A, Wilson S, Burgess C, Eadie D, Fitzgerald N, McKell J, Reid G, Jepson R, McAteer J, Bauld L.

BMC Public Health. 2017 Apr 24;17(1):357. doi: 10.1186/s12889-017-4256-1.


Impact of viral hepatitis aetiology on survival outcomes in hepatocellular carcinoma: A large multicentre cohort study.

Mgaieth S, Kemp W, Gow P, Fink M, Lubel J, Nicoll A, Gazzola A, Hong T, Ryan M, Knight V, Dev AT, Sood S, Bell S, Paul E, Roberts SK.

J Viral Hepat. 2017 Nov;24(11):982-989. doi: 10.1111/jvh.12717. Epub 2017 Jun 9.


Central Fetal Monitoring With and Without Computer Analysis: A Randomized Controlled Trial.

Nunes I, Ayres-de-Campos D, Ugwumadu A, Amin P, Banfield P, Nicoll A, Cunningham S, Sousa P, Costa-Santos C, Bernardes J; Fetal Monitoring and Alert (FM-ALERT) Study Group.

Obstet Gynecol. 2017 Jan;129(1):83-90. doi: 10.1097/AOG.0000000000001799.


Five-year efficacy and safety of tenofovir-based salvage therapy for patients with chronic hepatitis B who previously failed LAM/ADV therapy.

Lim L, Thompson A, Patterson S, George J, Strasser S, Lee A, Sievert W, Nicoll A, Desmond P, Roberts S, Marion K, Bowden S, Locarnini S, Angus P.

Liver Int. 2017 Jun;37(6):827-835. doi: 10.1111/liv.13331. Epub 2016 Dec 22.


HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.

Warne CD, Zaloumis SG, Bertalli NA, Delatycki MB, Nicoll AJ, McLaren CE, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Allen KJ, Gurrin LC; HealthIron Study Investigators.

J Gastroenterol Hepatol. 2017 Apr;32(4):797-802. doi: 10.1111/jgh.13621.


How should hyperferritinaemia be investigated and managed?

Ong SY, Nicoll AJ, Delatycki MB.

Eur J Intern Med. 2016 Sep;33:21-7. doi: 10.1016/j.ejim.2016.05.014. Epub 2016 Jun 23. Review.


Acoustic radiation force impulse accuracy and the impact of hepatic steatosis on liver fibrosis staging.

Harris N, Nadebaum D, Christie M, Gorelik A, Nicoll A, Sood S, Gibson R.

J Med Imaging Radiat Oncol. 2016 Oct;60(5):587-592. doi: 10.1111/1754-9485.12482. Epub 2016 Jun 21.


Sorafenib in the treatment of hepatocellular carcinoma: a multi-centre real-world study.

Doyle A, Marsh P, Gill R, Rodov M, Mohsen W, Varma P, Hong T, Strasser SI, Bell S, Ryan M, Nicoll A, Lubel J, Gow PJ, Fink MA, Roberts S, Kemp W, Kronborg I, Arachchi N, Knight V, Dev A.

Scand J Gastroenterol. 2016 Aug;51(8):979-85. doi: 10.3109/00365521.2016.1166518. Epub 2016 May 10.


A randomised controlled trial of a Mediterranean Dietary Intervention for Adults with Non Alcoholic Fatty Liver Disease (MEDINA): study protocol.

Papamiltiadous ES, Roberts SK, Nicoll AJ, Ryan MC, Itsiopoulos C, Salim A, Tierney AC.

BMC Gastroenterol. 2016 Feb 2;16:14. doi: 10.1186/s12876-016-0426-3.


Macrophage activation marker soluble CD163 may predict disease progression in hepatocellular carcinoma.

Kazankov K, Rode A, Simonsen K, Villadsen GE, Nicoll A, Møller HJ, Lim L, Angus P, Kronborg I, Arachchi N, Gorelik A, Liew D, Vilstrup H, Frystyk J, Grønbæk H.

Scand J Clin Lab Invest. 2016;76(1):64-73. doi: 10.3109/00365513.2015.1099722. Epub 2015 Nov 7.


Novel population-based study finding higher than reported hepatocellular carcinoma incidence suggests an updated approach is needed.

Hong TP, Gow P, Fink M, Dev A, Roberts S, Nicoll A, Lubel J, Kronborg I, Arachchi N, Ryan M, Kemp W, Knight V, Farrugia H, Thursfield V, Desmond P, Thompson AJ, Bell S.

Hepatology. 2016 Apr;63(4):1205-12. doi: 10.1002/hep.28267. Epub 2016 Feb 19.


Erratum: Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy.

Jaunmuktane Z, Mead S, Ellis M, Wadsworth JD, Nicoll AJ, Kenny J, Launchbury F, Linehan J, Richard-Loendt A, Walker AS, Rudge P, Collinge J, Brandner S.

Nature. 2015 Oct 22;526(7574):595. doi: 10.1038/nature15704. Epub 2015 Sep 16. No abstract available.


Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy.

Jaunmuktane Z, Mead S, Ellis M, Wadsworth JD, Nicoll AJ, Kenny J, Launchbury F, Linehan J, Richard-Loendt A, Walker AS, Rudge P, Collinge J, Brandner S.

Nature. 2015 Sep 10;525(7568):247-50. doi: 10.1038/nature15369. Erratum in: Nature. 2015 Oct 22;526(7574):595.


Circulating CD147 predicts mortality in advanced hepatocellular carcinoma.

Lee A, Rode A, Nicoll A, Maczurek AE, Lim L, Lim S, Angus P, Kronborg I, Arachchi N, Gorelik A, Liew D, Warner FJ, McCaughan GW, McLennan SV, Shackel NA.

J Gastroenterol Hepatol. 2016 Feb;31(2):459-66. doi: 10.1111/jgh.13148.


Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron).

Ong SY, Dolling L, Dixon JL, Nicoll AJ, Gurrin LC, Wolthuizen M, Wood EM, Anderson GJ, Ramm GA, Allen KJ, Olynyk JK, Crawford D, Kava J, Ramm LE, Gow P, Durrant S, Powell LW, Delatycki MB.

BMJ Open. 2015 Aug 12;5(8):e008938. doi: 10.1136/bmjopen-2015-008938.


Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay.

Risse E, Nicoll AJ, Taylor WA, Wright D, Badoni M, Yang X, Farrow MA, Collinge J.

J Biol Chem. 2015 Jul 3;290(27):17020-8. doi: 10.1074/jbc.M115.637124. Epub 2015 May 20.


Reduced mortality due to phlebotomy in moderately iron-loaded HFE haemochromatosis? The need for clinical trials.

Delatycki MB, Gurrin LC, Ong SY, Ramm GA, Anderson GJ, Olynyk JK, Allen KJ, Nicoll AJ, Powell LW.

J Hepatol. 2015 Jul;63(1):282-3. doi: 10.1016/j.jhep.2015.03.028. Epub 2015 Apr 1. No abstract available.


Assessment of human influenza pandemic scenarios in Europe.

Napoli C, Fabiani M, Rizzo C, Barral M, Oxford J, Cohen J, Niddam L, Goryński P, Pistol A, Lionis C, Briand S, Nicoll A, Penttinen P, Gauci C, Bounekkar A, Bonnevay S, Beresniak A.

Euro Surveill. 2015 Feb 19;20(7):29-38. Review. No abstract available.


Radiofrequency ablation versus resection for the treatment of early stage hepatocellular carcinoma: a multicenter Australian study.

Gory I, Fink M, Bell S, Gow P, Nicoll A, Knight V, Dev A, Rode A, Bailey M, Cheung W, Kemp W, Roberts SK; Melbourne Liver Group.

Scand J Gastroenterol. 2015 May;50(5):567-76. doi: 10.3109/00365521.2014.953572. Epub 2015 Jan 23.


Natural history of HFE simple heterozygosity for C282Y and H63D: a prospective 12-year study.

Zaloumis SG, Allen KJ, Bertalli NA, Turkovic L, Delatycki MB, Nicoll AJ, McLaren CE, English DR, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Gurrin LC; HealthIron Study Investigators.

J Gastroenterol Hepatol. 2015 Apr;30(4):719-25. doi: 10.1111/jgh.12804.


C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.

Mizielinska S, Grönke S, Niccoli T, Ridler CE, Clayton EL, Devoy A, Moens T, Norona FE, Woollacott IOC, Pietrzyk J, Cleverley K, Nicoll AJ, Pickering-Brown S, Dols J, Cabecinha M, Hendrich O, Fratta P, Fisher EMC, Partridge L, Isaacs AM.

Science. 2014 Sep 5;345(6201):1192-1194. doi: 10.1126/science.1256800. Epub 2014 Aug 7.


The changing place of liver biopsy in clinical practice: an audit of an Australian tertiary hospital.

Varma P, Jayasekera C, Gibson RN, Stella DL, Nicoll AJ.

Intern Med J. 2014 Aug;44(8):805-8. doi: 10.1111/imj.12503. Review.


N-terminal domain of prion protein directs its oligomeric association.

Trevitt CR, Hosszu LL, Batchelor M, Panico S, Terry C, Nicoll AJ, Risse E, Taylor WA, Sandberg MK, Al-Doujaily H, Linehan JM, Saibil HR, Scott DJ, Collinge J, Waltho JP, Clarke AR.

J Biol Chem. 2014 Sep 12;289(37):25497-508. doi: 10.1074/jbc.M114.566588. Epub 2014 Jul 29.


Vitamin B₁₂ and its binding proteins in hepatocellular carcinoma and chronic liver diseases.

Simonsen K, Rode A, Nicoll A, Villadsen G, Espelund U, Lim L, Angus P, Arachchi N, Vilstrup H, Nexo E, Grønbæk H.

Scand J Gastroenterol. 2014 Sep;49(9):1096-102. doi: 10.3109/00365521.2014.921325. Epub 2014 Jun 24.


Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity.

Klyubin I, Nicoll AJ, Khalili-Shirazi A, Farmer M, Canning S, Mably A, Linehan J, Brown A, Wakeling M, Brandner S, Walsh DM, Rowan MJ, Collinge J.

J Neurosci. 2014 Apr 30;34(18):6140-5. doi: 10.1523/JNEUROSCI.3526-13.2014.

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