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Items: 1 to 50 of 797

1.

Abnormal Hippocampal Melatoninergic System: A Potential Link between Absence Epilepsy and Depression-Like Behavior in WAG/Rij Rats?

Moyanova S, De Fusco A, Santolini I, Celli R, Bucci D, Mastroiacovo F, Battaglia G, Nicoletti F, Tchekalarova J.

Int J Mol Sci. 2018 Jul 6;19(7). pii: E1973. doi: 10.3390/ijms19071973.

2.

Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis.

Fagone P, Mazzon E, Chikovani T, Saraceno A, Mammana S, Colletti G, Mangano K, Bramanti P, Nicoletti F.

J Neuroimmunol. 2018 Aug 15;321:41-48. doi: 10.1016/j.jneuroim.2018.05.013. Epub 2018 May 28.

PMID:
29957387
3.

Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences.

Fagone P, Mazzon E, Cavalli E, Bramanti A, Petralia MC, Mangano K, Al-Abed Y, Bramati P, Nicoletti F.

J Neuroimmunol. 2018 Jun 15. pii: S0165-5728(18)30141-3. doi: 10.1016/j.jneuroim.2018.06.009. [Epub ahead of print]

4.

Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: Are they different entities?

Belizna C, Stojanovich L, Cohen-Tervaert JW, Fassot C, Henrion D, Loufrani L, Nagy G, Muchardt C, Hasan M, Ungeheuer MN, Arnaud L, Aliotaj-Reig J, Esteve-Valverde E, Nicoletti F, Saulnier P, Godon A, Reynier P, Chrétien JM, Damian L, Omarjee L, Mahé G, Pistorius MA, Meroni PL, Devreese K.

Autoimmun Rev. 2018 Jun 6. pii: S1568-9972(18)30138-1. doi: 10.1016/j.autrev.2018.01.027. [Epub ahead of print] Review.

PMID:
29885541
5.

5-HT2A receptor-dependent phosphorylation of mGlu2 receptor at Serine 843 promotes mGlu2 receptor-operated Gi/o signaling.

Murat S, Bigot M, Chapron J, König GM, Kostenis E, Battaglia G, Nicoletti F, Bourinet E, Bockaert J, Marin P, Vandermoere F.

Mol Psychiatry. 2018 Jun 1. doi: 10.1038/s41380-018-0069-6. [Epub ahead of print]

PMID:
29858599
6.

Editorial overview: Neurosciences: Metabotropic glutamate receptors: still promising drug targets for CNS disorders.

Nicoletti F, Battaglia G, Bruno V.

Curr Opin Pharmacol. 2018 Feb;38:v-vii. doi: 10.1016/j.coph.2018.04.013. No abstract available.

PMID:
29751975
7.

Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach.

Mangano K, Mazzon E, Basile MS, Di Marco R, Bramanti P, Mammana S, Petralia MC, Fagone P, Nicoletti F.

Oncotarget. 2018 Apr 3;9(25):17951-17970. doi: 10.18632/oncotarget.24885. eCollection 2018 Apr 3. Review.

8.

Stress as risk factor for Alzheimer's disease.

Caruso A, Nicoletti F, Mango D, Saidi A, Orlando R, Scaccianoce S.

Pharmacol Res. 2018 Jun;132:130-134. doi: 10.1016/j.phrs.2018.04.017. Epub 2018 Apr 22. Review.

PMID:
29689315
9.

Genetic rescue of absence seizures.

McCafferty C, Connelly WM, Celli R, Ngomba RT, Nicoletti F, Crunelli V.

CNS Neurosci Ther. 2018 Apr 23. doi: 10.1111/cns.12858. [Epub ahead of print] No abstract available.

PMID:
29687641
10.

Meet Our Regional Editor.

Nicoletti F.

Curr Neuropharmacol. 2018 Feb;16(2):117. doi: 10.2174/1570159X1602180130155228. No abstract available.

PMID:
29681788
11.

Naturally occurring compounds in differentiation based therapy of cancer.

Mijatović S, Bramanti A, Nicoletti F, Fagone P, Kaluđerović GN, Maksimović-Ivanić D.

Biotechnol Adv. 2018 Apr 12. pii: S0734-9750(18)30073-9. doi: 10.1016/j.biotechadv.2018.04.001. [Epub ahead of print] Review.

PMID:
29656090
12.

Reduced maternal behavior caused by gestational stress is predictive of life span changes in risk-taking behavior and gene expression due to altering of the stress/anti-stress balance.

Gatta E, Mairesse J, Deruyter L, Marrocco J, Van Camp G, Bouwalerh H, Lo Guidice JM, Morley-Fletcher S, Nicoletti F, Maccari S.

Neurotoxicology. 2018 May;66:138-149. doi: 10.1016/j.neuro.2018.04.005. Epub 2018 Apr 6.

PMID:
29630914
13.

Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria.

Nardecchia F, Orlando R, Iacovelli L, Colamartino M, Fiori E, Leuzzi V, Piccinin S, Nistico R, Puglisi-Allegra S, Di Menna L, Battaglia G, Nicoletti F, Pascucci T.

Front Neurosci. 2018 Mar 16;12:154. doi: 10.3389/fnins.2018.00154. eCollection 2018.

14.

Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells.

Graziano ACE, Avola R, Perciavalle V, Nicoletti F, Cicala G, Coco M, Cardile V.

World J Stem Cells. 2018 Mar 26;10(3):23-33. doi: 10.4252/wjsc.v10.i3.23. Review.

15.

The reduction in glutamate release is predictive of cognitive and emotional alterations that are corrected by the positive modulator of AMPA receptors S 47445 in perinatal stressed rats.

Morley-Fletcher S, Zuena AR, Mairesse J, Gatta E, Van Camp G, Bouwalerh H, Riozzi B, Battaglia G, Pittaluga A, Olivero G, Mocaer E, Bretin S, Nicoletti F, Maccari S.

Neuropharmacology. 2018 Jun;135:284-296. doi: 10.1016/j.neuropharm.2018.03.018. Epub 2018 Mar 23.

PMID:
29578034
16.

The Role of Macrophages in Neuroinflammatory and Neurodegenerative Pathways of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis: Pathogenetic Cellular Effectors and Potential Therapeutic Targets.

Mammana S, Fagone P, Cavalli E, Basile MS, Petralia MC, Nicoletti F, Bramanti P, Mazzon E.

Int J Mol Sci. 2018 Mar 13;19(3). pii: E831. doi: 10.3390/ijms19030831. Review.

17.

Targeting metabotropic glutamate receptors in the treatment of primary brain tumors.

Iacovelli L, Orlando R, Rossi A, Spinsanti P, Melchiorri D, Nicoletti F.

Curr Opin Pharmacol. 2018 Feb;38:59-64. doi: 10.1016/j.coph.2018.02.005. Epub 2018 Mar 8. Review.

PMID:
29525720
18.

Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis.

Mammana S, Bramanti P, Mazzon E, Cavalli E, Basile MS, Fagone P, Petralia MC, McCubrey JA, Nicoletti F, Mangano K.

Oncotarget. 2018 Jan 3;9(9):8263-8277. doi: 10.18632/oncotarget.23862. eCollection 2018 Feb 2.

19.

Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target.

Caraci F, Spampinato SF, Morgese MG, Tascedda F, Salluzzo MG, Giambirtone MC, Caruso G, Munafò A, Torrisi SA, Leggio GM, Trabace L, Nicoletti F, Drago F, Sortino MA, Copani A.

Pharmacol Res. 2018 Apr;130:374-384. doi: 10.1016/j.phrs.2018.02.007. Epub 2018 Feb 10. Review.

PMID:
29438781
20.

Ageing: from inflammation to cancer.

Leonardi GC, Accardi G, Monastero R, Nicoletti F, Libra M.

Immun Ageing. 2018 Jan 19;15:1. doi: 10.1186/s12979-017-0112-5. eCollection 2018. Review.

21.

Selective Blockade of the Metabotropic Glutamate Receptor mGluR5 Protects Mouse Livers in In Vitro and Ex Vivo Models of Ischemia Reperfusion Injury.

Ferrigno A, Berardo C, Di Pasqua LG, Siciliano V, Richelmi P, Nicoletti F, Vairetti M.

Int J Mol Sci. 2018 Jan 23;19(2). pii: E314. doi: 10.3390/ijms19020314.

22.

Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator.

Font J, López-Cano M, Notartomaso S, Scarselli P, Di Prieto P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, Nicoletti F, Llebaria A, Ciruela F.

Elife. 2018 Jan 8;7. pii: e34752. doi: 10.7554/eLife.34752. No abstract available.

23.

Metabotropic glutamate receptors: the potential for therapeutic applications in Alzheimer's disease.

Caraci F, Nicoletti F, Copani A.

Curr Opin Pharmacol. 2018 Feb;38:1-7. doi: 10.1016/j.coph.2017.12.001. Epub 2017 Dec 23. Review.

PMID:
29278824
24.

A small dose of apomorphine counteracts the deleterious effects of middle cerebral artery occlusion in different models.

Mastroiacovo F, Gaglione A, Busceti CL, Ryskalin L, Bozza G, Nicoletti F, Orzi F, Fornai F.

Arch Ital Biol. 2017 Sep 1;155(3):110-117. doi: 10.12871/00039829201732.

PMID:
29220863
25.

Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death.

Beneventano M, Spampinato SF, Merlo S, Chisari M, Platania P, Ragusa M, Purrello M, Nicoletti F, Sortino MA.

Front Pharmacol. 2017 Nov 9;8:812. doi: 10.3389/fphar.2017.00812. eCollection 2017.

26.

Systematic Morphometry of Catecholamine Nuclei in the Brainstem.

Bucci D, Busceti CL, Calierno MT, Di Pietro P, Madonna M, Biagioni F, Ryskalin L, Limanaqi F, Nicoletti F, Fornai F.

Front Neuroanat. 2017 Nov 2;11:98. doi: 10.3389/fnana.2017.00098. eCollection 2017.

27.

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system.

Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F.

Neuropharmacology. 2018 Jan;128:301-313. doi: 10.1016/j.neuropharm.2017.10.026. Epub 2017 Oct 25.

PMID:
29079293
28.

Involvement of the Nrf2/HO-1/CO axis and therapeutic intervention with the CO-releasing molecule CORM-A1, in a murine model of autoimmune hepatitis.

Mangano K, Cavalli E, Mammana S, Basile MS, Caltabiano R, Pesce A, Puleo S, Atanasov AG, Magro G, Nicoletti F, Fagone P.

J Cell Physiol. 2018 May;233(5):4156-4165. doi: 10.1002/jcp.26223. Epub 2017 Dec 29.

PMID:
29034470
29.

Immuno-pharmacological characterization of group II metabotropic glutamate receptors controlling glutamate exocytosis in mouse cortex and spinal cord.

Olivero G, Bonfiglio T, Vergassola M, Usai C, Riozzi B, Battaglia G, Nicoletti F, Pittaluga A.

Br J Pharmacol. 2017 Dec;174(24):4785-4796. doi: 10.1111/bph.14061. Epub 2017 Oct 29.

PMID:
28967122
30.

Evaluation of hyaluronic acid-P40 conjugated cream in a mouse model of dermatitis induced by oxazolone.

Mangano K, Vergalito F, Mammana S, Mariano A, De Pasquale R, Meloscia A, Bartollino S, Guerra G, Nicoletti F, Di Marco R.

Exp Ther Med. 2017 Sep;14(3):2439-2444. doi: 10.3892/etm.2017.4810. Epub 2017 Jul 19.

31.

Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration.

Liberatore F, Bucci D, Mascio G, Madonna M, Di Pietro P, Beneventano M, Puliti AM, Battaglia G, Bruno V, Nicoletti F, Romano MR.

Neuroscience. 2017 Nov 5;363:142-149. doi: 10.1016/j.neuroscience.2017.09.005. Epub 2017 Sep 14.

PMID:
28918254
32.

Alterations in the α2 δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies.

Santolini I, Celli R, Cannella M, Imbriglio T, Guiducci M, Parisi P, Schubert J, Iacomino M, Zara F, Lerche H; EuroEPINOMICS CoGIE Consortium; Genetic Commission of Italian League Against Epilepsy (LICE), Moyanova S, Ngomba RT, van Luijtelaar G, Battaglia G, Bruno V, Striano P, Nicoletti F.

Epilepsia. 2017 Nov;58(11):1993-2001. doi: 10.1111/epi.13898. Epub 2017 Sep 15.

PMID:
28913875
33.

Genetic deletion of mGlu2 metabotropic glutamate receptors improves the short-term outcome of cerebral transient focal ischemia.

Mastroiacovo F, Moyanova S, Cannella M, Gaglione A, Verhaeghe R, Bozza G, Madonna M, Motolese M, Traficante A, Riozzi B, Bruno V, Battaglia G, Lodge D, Nicoletti F.

Mol Brain. 2017 Aug 18;10(1):39. doi: 10.1186/s13041-017-0319-6.

34.

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

Donia M, Harbst K, van Buuren M, Kvistborg P, Lindberg MF, Andersen R, Idorn M, Munir Ahmad S, Ellebæk E, Mueller A, Fagone P, Nicoletti F, Libra M, Lauss M, Hadrup SR, Schmidt H, Andersen MH, Thor Straten P, Nilsson JA, Schumacher TN, Seliger B, Jönsson G, Svane IM.

Cancer Res. 2017 Sep 1;77(17):4562-4566. doi: 10.1158/0008-5472.CAN-16-3172. Epub 2017 Jun 27.

PMID:
28655789
35.

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.

McCubrey JA, Lertpiriyapong K, Steelman LS, Abrams SL, Yang LV, Murata RM, Rosalen PL, Scalisi A, Neri LM, Cocco L, Ratti S, Martelli AM, Laidler P, Dulińska-Litewka J, Rakus D, Gizak A, Lombardi P, Nicoletti F, Candido S, Libra M, Montalto G, Cervello M.

Aging (Albany NY). 2017 Jun 12;9(6):1477-1536. doi: 10.18632/aging.101250. Review.

36.

Changes in serum levels of kynurenine metabolites in paediatric patients affected by ADHD.

Evangelisti M, De Rossi P, Rabasco J, Donfrancesco R, Lionetto L, Capi M, Sani G, Simmaco M, Nicoletti F, Villa MP.

Eur Child Adolesc Psychiatry. 2017 Dec;26(12):1433-1441. doi: 10.1007/s00787-017-1002-2. Epub 2017 May 19.

PMID:
28527020
37.

Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?

Fazio F, Carrizzo A, Lionetto L, Damato A, Capocci L, Ambrosio M, Battaglia G, Bruno V, Madonna M, Simmaco M, Nicoletti F, Vecchione C.

Front Pharmacol. 2017 May 1;8:214. doi: 10.3389/fphar.2017.00214. eCollection 2017.

38.

Potential Use of Modulators of Oxidative Stress as Add-on Therapy in Patients with Anxiety Disorders.

Boldrini P, Fusco A, Nicoletti F, Badiani A, Saso L.

Curr Drug Targets. 2018;19(6):636-650. doi: 10.2174/1389450118666170425153356.

PMID:
28443504
39.

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator.

Font J, López-Cano M, Notartomaso S, Scarselli P, Di Pietro P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, Nicoletti F, Llebaria A, Ciruela F.

Elife. 2017 Apr 11;6. pii: e23545. doi: 10.7554/eLife.23545. Erratum in: Elife. 2018 Jan 08;7:.

40.

Dickkopf-3 Upregulates VEGF in Cultured Human Endothelial Cells by Activating Activin Receptor-Like Kinase 1 (ALK1) Pathway.

Busceti CL, Marchitti S, Bianchi F, Di Pietro P, Riozzi B, Stanzione R, Cannella M, Battaglia G, Bruno V, Volpe M, Fornai F, Nicoletti F, Rubattu S.

Front Pharmacol. 2017 Mar 14;8:111. doi: 10.3389/fphar.2017.00111. eCollection 2017.

41.

Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain.

Notartomaso S, Mascio G, Bernabucci M, Zappulla C, Scarselli P, Cannella M, Imbriglio T, Gradini R, Battaglia G, Bruno V, Nicoletti F.

Mol Pain. 2017 Jan;13:1744806917697009. doi: 10.1177/1744806917697009.

42.

Identification of novel chemotherapeutic strategies for metastatic uveal melanoma.

Fagone P, Caltabiano R, Russo A, Lupo G, Anfuso CD, Basile MS, Longo A, Nicoletti F, De Pasquale R, Libra M, Reibaldi M.

Sci Rep. 2017 Mar 17;7:44564. doi: 10.1038/srep44564.

43.

The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?

Celli R, Santolini I, Guiducci M, van Luijtelaar G, Parisi P, Striano P, Gradini R, Battaglia G, Ngomba RT, Nicoletti F.

Curr Neuropharmacol. 2017;15(6):918-925. doi: 10.2174/1570159X15666170309105451. Review.

44.

The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus.

Weisz F, Piccinin S, Mango D, Ngomba RT, Mercuri NB, Nicoletti F, Nisticò R.

Synapse. 2017 May;71(5). doi: 10.1002/syn.21964. Epub 2017 Feb 21.

PMID:
28187508
45.

Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus.

Mango D, Braksator E, Battaglia G, Marcelli S, Mercuri NB, Feligioni M, Nicoletti F, Bashir ZI, Nisticò R.

Pharmacol Res. 2017 May;119:12-19. doi: 10.1016/j.phrs.2017.01.028. Epub 2017 Jan 27.

PMID:
28137639
46.

Kynurenine pathway metabolites in migraine.

Nicoletti F.

J Headache Pain. 2015 Dec;16(Suppl 1):A1. doi: 10.1186/1129-2377-16-S1-A1. No abstract available. Erratum in: J Headache Pain. 2017 Dec;18(1):11.

47.

O066. Kynurenine pathway metabolites in cluster headache.

Curto M, Lionetto L, Capi M, Negro A, D'Alonzo L, Nicoletti F, Martelletti P.

J Headache Pain. 2015 Dec;16(Suppl 1):A87. doi: 10.1186/1129-2377-16-S1-A87. No abstract available. Erratum in: J Headache Pain. 2017 Dec;18(1):11.

48.

Anti-angiogenic Therapy in Cancer: Downsides and New Pivots for Precision Medicine.

Lupo G, Caporarello N, Olivieri M, Cristaldi M, Motta C, Bramanti V, Avola R, Salmeri M, Nicoletti F, Anfuso CD.

Front Pharmacol. 2017 Jan 6;7:519. doi: 10.3389/fphar.2016.00519. eCollection 2016. Review.

49.

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells.

McCubrey JA, Fitzgerald TL, Yang LV, Lertpiriyapong K, Steelman LS, Abrams SL, Montalto G, Cervello M, Neri LM, Cocco L, Martelli AM, Laidler P, Dulińska-Litewka J, Rakus D, Gizak A, Nicoletti F, Falzone L, Candido S, Libra M.

Oncotarget. 2017 Feb 21;8(8):14221-14250. doi: 10.18632/oncotarget.13991. Review.

50.

Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents.

Magro G, Salvatorelli L, Alaggio R, D'Agata V, Nicoletti F, Di Cataldo A, Parenti R.

Hum Pathol. 2017 Feb;60:58-65. doi: 10.1016/j.humpath.2016.07.038. Epub 2016 Oct 28.

PMID:
27984122

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