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Items: 46

1.

Polysaccharide from Gracilaria caudata protects the human esophageal mucosal barrier: A differential topical effect and structural dependence.

Sales TMAL, Nicolau LAD, Rodrigues RLM, Nascimento RR, Paula SM, da Costa-Filho HB, Bezerra FF, Santos GRC, Barros FCN, Alencar POC, Freitas ALP, Nobre-Souza MÂ, Santos AA, Sifrim D, Soares PMG, Silva RO, Souza MHLP.

Int J Biol Macromol. 2020 Feb 10;150:354-361. doi: 10.1016/j.ijbiomac.2020.02.074. [Epub ahead of print]

PMID:
32057860
2.

Biopolymer Extracted from Anadenanthera colubrina (Red Angico Gum) Exerts Therapeutic Potential in Mice: Antidiarrheal Activity and Safety Assessment.

Araújo TSL, de Oliveira TM, de Sousa NA, Souza LKM, Sousa FBM, de Oliveira AP, Nicolau LAD, da Silva AAV, Araújo AR, Magalhães PJC, Vasconcelos DFP, de Jonge HR, Souza MHLP, Silva DA, Paula RCM, Medeiros JVR.

Pharmaceuticals (Basel). 2020 Jan 18;13(1). pii: E17. doi: 10.3390/ph13010017.

3.

Cashew gum, a biopolymer, topically protects oesophageal mucosa in non erosive reflux disease: A promising translational study.

Nicolau LAD, Batista-Lima FJ, Santana APM, Sales TMAL, Carmo-Neto JP, Freitas GB, Oliveira TM, Medeiros JVR, Silva DA, Lee C, Woodland PJ, Soares PMG, Vale ML, Santos AA, Sifrim D, Souza MHLP.

Carbohydr Polym. 2019 Dec 15;226:115205. doi: 10.1016/j.carbpol.2019.115205. Epub 2019 Aug 15.

PMID:
31582062
4.

Efficacy of a phenol derivative, isopropyl vanillate, as an anti-inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration.

Nogueira KM, de Souza LKM, de Oliveira AP, Pacheco G, Iles B, Alencar MS, Nicolau LAD, Silva RO, da Nóbrega FR, Sousa DP, de Souza MHLP, Medeiros JVR.

Drug Dev Res. 2019 Aug;80(5):666-679. doi: 10.1002/ddr.21546. Epub 2019 May 21.

PMID:
31112325
5.

Cardiovascular Effect of Diosgenin in Ovariectomized Rats.

Morais ICPS, Moura IJL, Sabino CKB, Nicolau LAD, Souza FM, Silva-Filho JCD, Oliveira RCM, Medeiros JVR, Lima SG, Oliveira AP.

J Med Food. 2019 Mar;22(3):248-256. doi: 10.1089/jmf.2018.0019. Epub 2019 Feb 8.

PMID:
30735081
6.

Pru p 7 sensitization is a predominant cause of severe, cypress pollen-associated peach allergy.

Klingebiel C, Chantran Y, Arif-Lusson R, Ehrenberg AE, Östling J, Poisson A, Liabeuf V, Agabriel C, Birnbaum J, Porri F, Sarrat A, Apoil PA, Vivinus M, Garnier L, Chiriac AM, Caimmi DP, Bourrain JL, Demoly P, Guez S, Boralevi F, Lovato B, Palussière C, Leroy S, Bourrier T, Giovannini-Chami L, Gouitaa M, Aferiat-Derome A, Charpin D, Sofalvi T, Cabon-Boudard I, Massabie-Bouchat YP, Hofmann B, Bonardel N, Dron-Gonzalvez M, Sterling B, Carsin A, Vivinus S, Poitevin B, Nicolau L, Liautard G, Soler C, Mezouar S, Annesi-Maesano I, Mège JL, Lidholm J, Vitte J; ANAFORCAL and AllergoBioNet Networks.

Clin Exp Allergy. 2019 Apr;49(4):526-536. doi: 10.1111/cea.13345. Epub 2019 Feb 19.

7.

Herpesvirus infection in marine mammals: A retrospective molecular survey of stranded cetaceans in the Portuguese coastline.

Bento MC, Canha R, Eira C, Vingada J, Nicolau L, Ferreira M, Domingo M, Tavares L, Duarte A.

Infect Genet Evol. 2019 Jan;67:222-233. doi: 10.1016/j.meegid.2018.11.013. Epub 2018 Nov 14.

PMID:
30445114
8.

AMPK activation promotes gastroprotection through mutual interaction with the gaseous mediators H2S, NO, and CO.

de Araújo S, Oliveira AP, Sousa FBM, Souza LKM, Pacheco G, Filgueiras MC, Nicolau LAD, Brito GAC, Cerqueira GS, Silva RO, Souza MHLP, Medeiros JVR.

Nitric Oxide. 2018 Aug 1;78:60-71. doi: 10.1016/j.niox.2018.05.008. Epub 2018 May 30.

PMID:
29857061
9.

Topical protection of mice laryngeal mucosa using the natural product cashew gum.

Figueiredo AA, Santana APM, Nicolau LAD, Batista-Lima FJ, Wong DVT, Lucetti LT, Batista GLP, Caminha NA, Medeiros JVR, Silva DA, Leite JRSA, Santos AA, Soares PMG, Sifrim D, Souza MHLP.

Laryngoscope. 2018 May;128(5):1157-1162. doi: 10.1002/lary.26958. Epub 2017 Oct 27.

PMID:
29076531
10.

H2S is a key antisecretory molecule against cholera toxin-induced diarrhoea in mice: Evidence for non-involvement of the AC/cAMP/PKA pathway and AMPK.

Sousa FBM, Souza LKM, Sousa NA, Araújo TSL, de Araújo S, Pacífico DM, Silva IS, Silva RO, Nicolau LAD, Souza FM, Filgueiras MC, Oliveira JS, Souza MHLP, Medeiros JVR.

Nitric Oxide. 2018 Jun 1;76:152-163. doi: 10.1016/j.niox.2017.09.007. Epub 2017 Sep 22.

PMID:
28943473
11.

Diet of bottlenose dolphins (Tursiops truncatus) from the Gulf of Cadiz: Insights from stomach content and stable isotope analyses.

Giménez J, Marçalo A, Ramírez F, Verborgh P, Gauffier P, Esteban R, Nicolau L, González-Ortegón E, Baldó F, Vilas C, Vingada J, G Forero M, de Stephanis R.

PLoS One. 2017 Sep 12;12(9):e0184673. doi: 10.1371/journal.pone.0184673. eCollection 2017.

12.

Lycopene rich extract from red guava (Psidium guajava L.) displays anti-inflammatory and antioxidant profile by reducing suggestive hallmarks of acute inflammatory response in mice.

Vasconcelos AG, Amorim ADGN, Dos Santos RC, Souza JMT, de Souza LKM, Araújo TSL, Nicolau LAD, de Lima Carvalho L, de Aquino PEA, da Silva Martins C, Ropke CD, Soares PMG, Kuckelhaus SAS, Medeiros JR, Leite JRSA.

Food Res Int. 2017 Sep;99(Pt 2):959-968. doi: 10.1016/j.foodres.2017.01.017. Epub 2017 Jan 21.

PMID:
28847433
13.

Evaluation of anti-inflammatory potential of aqueous extract and polysaccharide fraction of Thuja occidentalis Linn. in mice.

Silva IS, Nicolau LAD, Sousa FBM, Araújo S, Oliveira AP, Araújo TSL, Souza LKM, Martins CS, Aquino PEA, Carvalho LL, Silva RO, Rolim-Neto PJ, Medeiros JVR.

Int J Biol Macromol. 2017 Dec;105(Pt 1):1105-1116. doi: 10.1016/j.ijbiomac.2017.07.142. Epub 2017 Jul 24.

PMID:
28751047
14.

Trace elements in loggerhead turtles (Caretta caretta) stranded in mainland Portugal: Bioaccumulation and tissue distribution.

Nicolau L, Monteiro SS, Pereira AT, Marçalo A, Ferreira M, Torres J, Vingada J, Eira C.

Chemosphere. 2017 Jul;179:120-126. doi: 10.1016/j.chemosphere.2017.03.108. Epub 2017 Mar 27.

PMID:
28364647
15.

Bergenin from Peltophorum dubium: Isolation, Characterization, and Antioxidant Activities in Non-Biological Systems and Erythrocytes.

de Oliveira GAL, da Silva Oliveira GL, Nicolau LAD, Mafud AC, Batista LF, Mascarenhas YP, de Sousa LKM, David JM, Pinto LS, Alves CQ, Medeiros JVR.

Med Chem. 2017;13(6):592-603. doi: 10.2174/1573406413666170306120152.

PMID:
28266277
16.

Anti-Leishmania activity of essential oil of Myracrodruon urundeuva (Engl.) Fr. All.: Composition, cytotoxity and possible mechanisms of action.

Carvalho CE, Sobrinho-Junior EP, Brito LM, Nicolau LA, Carvalho TP, Moura AK, Rodrigues KA, Carneiro SM, Arcanjo DD, Citó AM, Carvalho FA.

Exp Parasitol. 2017 Apr;175:59-67. doi: 10.1016/j.exppara.2017.02.012. Epub 2017 Feb 9.

17.

The anti-inflammatory effects of N-methyl-(2S,4R)-trans-4-hydroxy-l-proline from Syderoxylon obtusifolium are related to its inhibition of TNF-alpha and inflammatory enzymes.

de Aquino PE, Magalhães TR, Nicolau LA, Leal LK, de Aquino NC, Dos Santos SM, Neves KR, Silveira ER, Viana GS.

Phytomedicine. 2017 Jan 15;24:14-23. doi: 10.1016/j.phymed.2016.11.010. Epub 2016 Nov 15.

18.

Evidence that d-cysteine protects mice from gastric damage via hydrogen sulfide produced by d-amino acid oxidase.

Souza LK, Araújo TS, Sousa NA, Sousa FB, Nogueira KM, Nicolau LA, Medeiros JV.

Nitric Oxide. 2017 Apr 1;64:1-6. doi: 10.1016/j.niox.2017.01.010. Epub 2017 Jan 27.

PMID:
28137610
19.

Physio-pharmacological Investigations About the Anti-inflammatory and Antinociceptive Efficacy of (+)-Limonene Epoxide.

de Almeida AA, Silva RO, Nicolau LA, de Brito TV, de Sousa DP, Barbosa AL, de Freitas RM, Lopes LD, Medeiros JR, Ferreira PM.

Inflammation. 2017 Apr;40(2):511-522. doi: 10.1007/s10753-016-0496-y.

PMID:
28091830
20.

Epiisopiloturine hydrochloride, an imidazole alkaloid isolated from Pilocarpus microphyllus leaves, protects against naproxen-induced gastrointestinal damage in rats.

Nicolau LAD, Carvalho NS, Pacífico DM, Lucetti LT, Aragão KS, Véras LMC, Souza MHLP, Leite JRSA, Medeiros JVR.

Biomed Pharmacother. 2017 Mar;87:188-195. doi: 10.1016/j.biopha.2016.12.101. Epub 2017 Jan 2.

PMID:
28056423
21.

Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.

Souza LK, Nicolau LA, Sousa NA, Araújo TS, Sousa FB, Costa DS, Souza FM, Pacífico DM, Martins CS, Silva RO, Souza MH, Cerqueira GS, Medeiros JV.

Biochem Pharmacol. 2016 Jul 15;112:50-9. doi: 10.1016/j.bcp.2016.05.010. Epub 2016 May 27.

PMID:
27241079
22.

Spatial distribution of floating marine debris in offshore continental Portuguese waters.

Sá S, Bastos-Santos J, Araújo H, Ferreira M, Duro V, Alves F, Panta-Ferreira B, Nicolau L, Eira C, Vingada J.

Mar Pollut Bull. 2016 Mar 15;104(1-2):269-78. doi: 10.1016/j.marpolbul.2016.01.011. Epub 2016 Jan 15.

PMID:
26778496
23.

Ingestion of marine litter by loggerhead sea turtles, Caretta caretta, in Portuguese continental waters.

Nicolau L, Marçalo A, Ferreira M, Sá S, Vingada J, Eira C.

Mar Pollut Bull. 2016 Feb 15;103(1-2):179-185. doi: 10.1016/j.marpolbul.2015.12.021. Epub 2016 Jan 4.

PMID:
26763321
24.

Ecological variables influencing trace element concentrations in bottlenose dolphins (Tursiops truncatus, Montagu 1821) stranded in continental Portugal.

Monteiro SS, Torres J, Ferreira M, Marçalo A, Nicolau L, Vingada JV, Eira C.

Sci Total Environ. 2016 Feb 15;544:837-44. doi: 10.1016/j.scitotenv.2015.12.037. Epub 2015 Dec 17.

PMID:
26706756
25.

Sulphated Polysaccharide Isolated from the Seaweed Gracilaria caudata Exerts an Antidiarrhoeal Effect in Rodents.

Costa DS, Araújo TS, Sousa NA, Souza LK, Pacífico DM, Sousa FB, Nicolau LA, Chaves LS, Barros FC, Freitas AL, Medeiros JV.

Basic Clin Pharmacol Toxicol. 2016 Jun;118(6):440-8. doi: 10.1111/bcpt.12531. Epub 2016 Jan 14.

26.

Protective Effects of Simvastatin Against Alendronate-Induced Gastric Mucosal Injury in Rats.

Carvalho NS, Silva MM, Silva RO, Nicolau LA, Araújo TS, Costa DS, Sousa NA, Souza LK, Soares PM, Medeiros JV.

Dig Dis Sci. 2016 Feb;61(2):400-9. doi: 10.1007/s10620-015-3890-7. Epub 2015 Sep 24.

PMID:
26403426
27.

Gastroprotective properties of cashew gum, a complex heteropolysaccharide of Anacardium occidentale, in naproxen-induced gastrointestinal damage in rats.

Carvalho NS, Silva MM, Silva RO, Nicolau LA, Sousa FB, Damasceno SR, Silva DA, Barbosa AL, Leite JR, Medeiros JV.

Drug Dev Res. 2015 May;76(3):143-51. doi: 10.1002/ddr.21250. Epub 2015 May 11.

PMID:
25959135
28.

Sleep is more sensitive to high doses of caffeine in the middle years of life.

Robillard R, Bouchard M, Cartier A, Nicolau L, Carrier J.

J Psychopharmacol. 2015 Jun;29(6):688-97. doi: 10.1177/0269881115575535. Epub 2015 Mar 10.

PMID:
25759402
29.

The hydrogen sulfide donor, Lawesson's reagent, prevents alendronate-induced gastric damage in rats.

Nicolau LA, Silva RO, Damasceno SR, Carvalho NS, Costa NR, Aragão KS, Barbosa AL, Soares PM, Souza MH, Medeiros JV.

Braz J Med Biol Res. 2013 Aug;46(8):708-14. doi: 10.1590/1414-431X20133030. Epub 2013 Aug 16.

30.

Role of soluble guanylate cyclase activation in the gastroprotective effect of the HO-1/CO pathway against alendronate-induced gastric damage in rats.

Costa NR, Silva RO, Nicolau LA, Lucetti LT, Santana AP, Aragão KS, Soares PM, Ribeiro RA, Souza MH, Barbosa AL, Medeiros JV.

Eur J Pharmacol. 2013 Jan 30;700(1-3):51-9. doi: 10.1016/j.ejphar.2012.12.007. Epub 2012 Dec 21.

31.

Antiinflammatory and antinociceptive effects in mice of a sulfated polysaccharide fraction extracted from the marine red algae Gracilaria caudata.

Chaves Lde S, Nicolau LA, Silva RO, Barros FC, Freitas AL, Aragão KS, Ribeiro Rde A, Souza MH, Barbosa AL, Medeiros JV.

Immunopharmacol Immunotoxicol. 2013 Feb;35(1):93-100. doi: 10.3109/08923973.2012.707211. Epub 2012 Jul 26.

PMID:
22830978
32.

Evaluation of key odorants in sauvignon blanc wines using three different methodologies.

Benkwitz F, Nicolau L, Lund C, Beresford M, Wohlers M, Kilmartin PA.

J Agric Food Chem. 2012 Jun 27;60(25):6293-302. doi: 10.1021/jf300914n. Epub 2012 Jun 18.

PMID:
22663147
33.

Sulfated-polysaccharide fraction from red algae Gracilaria caudata protects mice gut against ethanol-induced damage.

Silva RO, dos Santos GM, Nicolau LA, Lucetti LT, Santana AP, Chaves Lde S, Barros FC, Freitas AL, Souza MH, Medeiros JV.

Mar Drugs. 2011;9(11):2188-200. doi: 10.3390/md9112188. Epub 2011 Nov 2.

34.

Biotransformation modulation and genotoxicity in white seabream upon exposure to paralytic shellfish toxins produced by Gymnodinium catenatum.

Costa PR, Pereira P, Guilherme S, Barata M, Nicolau L, Santos MA, Pacheco M, Pousão-Ferreira P.

Aquat Toxicol. 2012 Jan 15;106-107:42-7. doi: 10.1016/j.aquatox.2011.08.023. Epub 2011 Sep 6.

PMID:
22057254
35.

Influence of grape-harvesting steps on varietal thiol aromas in Sauvignon blanc wines.

Allen T, Herbst-Johnstone M, Girault M, Butler P, Logan G, Jouanneau S, Nicolau L, Kilmartin PA.

J Agric Food Chem. 2011 Oct 12;59(19):10641-50. doi: 10.1021/jf2018676. Epub 2011 Sep 8.

PMID:
21854044
36.

The yeast IRC7 gene encodes a β-lyase responsible for production of the varietal thiol 4-mercapto-4-methylpentan-2-one in wine.

Roncoroni M, Santiago M, Hooks DO, Moroney S, Harsch MJ, Lee SA, Richards KD, Nicolau L, Gardner RC.

Food Microbiol. 2011 Aug;28(5):926-35. doi: 10.1016/j.fm.2011.01.002. Epub 2011 Jan 13.

PMID:
21569935
37.

Ethylene-regulated (methylsulfanyl)alkanoate ester biosynthesis is likely to be modulated by precursor availability in Actinidia chinensis genotypes.

Günther CS, Heinemann K, Laing WA, Nicolau L, Marsh KB.

J Plant Physiol. 2011 May 1;168(7):629-38. doi: 10.1016/j.jplph.2010.10.001. Epub 2010 Nov 10.

PMID:
21071110
38.

Pulsatility index change of brachial artery shows better reproducibility than flow-mediated vasodilation.

Lima JC, Martins WP, Nastri CO, Nicolau LG, Filho FM.

Ultrasound Med Biol. 2010 Dec;36(12):2036-41. doi: 10.1016/j.ultrasmedbio.2010.09.005. Epub 2010 Oct 28.

PMID:
21030139
39.

Influence of pregnancy and smoking on brachial artery flow-mediated dilation values and time until maximum response.

Nicolau LG, Martins WP, Gallarreta FM, Lima JC, Filho FM.

Arch Gynecol Obstet. 2011 Aug;284(2):313-7. doi: 10.1007/s00404-010-1667-y. Epub 2010 Sep 3.

PMID:
20814686
40.

Influence of juice pressing conditions on polyphenols, antioxidants, and varietal aroma of Sauvignon blanc microferments.

Patel P, Herbst-Johnstone M, Lee SA, Gardner RC, Weaver R, Nicolau L, Kilmartin PA.

J Agric Food Chem. 2010 Jun 23;58(12):7280-8. doi: 10.1021/jf100200e.

PMID:
20486689
41.

Evaluation of ductus venosus and inferior vena cava by using multiple Doppler ultrasound parameters in healthy fetuses.

Gallarreta FM, Martins WP, Nastri CO, Mauad Filho F, Nicolau LG, Barra DA, Morais EN, Crott GC.

Arch Gynecol Obstet. 2011 May;283(5):959-63. doi: 10.1007/s00404-010-1492-3. Epub 2010 May 5.

PMID:
20443013
42.

(Methylsulfanyl)alkanoate ester biosynthesis in Actinidia chinensis kiwifruit and changes during cold storage.

Günther CS, Matich AJ, Marsh KB, Nicolau L.

Phytochemistry. 2010 May;71(7):742-50. doi: 10.1016/j.phytochem.2010.01.016. Epub 2010 Feb 25.

PMID:
20189207
43.

[Lower uterine segment thickness measurement in pregnant women with previous caesarean section: intra- and interobserver reliability analysis using bi- and tridimensional ultrasonography].

Barra Dde A, Martins Wde P, Gallarretta FM, Nastri CO, Nicolau LG, Mauad Filho F.

Rev Bras Ginecol Obstet. 2008 Mar;30(3):142-8. Epub 2008 Feb 29. Portuguese.

PMID:
19145381
44.

[Evaluation of blood flow in the fetal renal artery between the 22nd and 38th week in normal pregnancies].

Gallarreta FM, Martins Wde P, de Morais EN, Ferreira Ada C, Nicolau LG, Barra Dde A, Mauad Filho F.

Rev Bras Ginecol Obstet. 2008 Oct;30(10):494-8. Portuguese.

PMID:
19082385
45.

Effect of skin contact and pressure on the composition of Sauvignon Blanc must.

Maggu M, Winz R, Kilmartin PA, Trought MC, Nicolau L.

J Agric Food Chem. 2007 Dec 12;55(25):10281-8. Epub 2007 Nov 20.

PMID:
18020411
46.

Effect of screwcap and cork closures on SO2 levels and aromas in a Sauvignon Blanc wine.

Brajkovich M, Tibbits N, Peron G, Lund CM, Dykes SI, Kilmartin PA, Nicolau L.

J Agric Food Chem. 2005 Dec 28;53(26):10006-11.

PMID:
16366687

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