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Items: 49


Early Steps in Herpes Simplex Virus Infection Blocked by a Proteasome Inhibitor.

Schneider SM, Pritchard SM, Wudiri GA, Trammell CE, Nicola AV.

MBio. 2019 May 14;10(3). pii: e00732-19. doi: 10.1128/mBio.00732-19.


Role of Sphingomyelin in Alphaherpesvirus Entry.

Pastenkos G, Miller JL, Pritchard SM, Nicola AV.

J Virol. 2019 Feb 19;93(5). pii: e01547-18. doi: 10.1128/JVI.01547-18. Print 2019 Mar 1.


Low-pH Endocytic Entry of the Porcine Alphaherpesvirus Pseudorabies Virus.

Miller JL, Weed DJ, Lee BH, Pritchard SM, Nicola AV.

J Virol. 2019 Jan 4;93(2). pii: e01849-18. doi: 10.1128/JVI.01849-18. Print 2019 Jan 15.


Bovine Herpesvirus 1 Entry by a Low-pH Endosomal Pathway.

Pastenkos G, Lee B, Pritchard SM, Nicola AV.

J Virol. 2018 Sep 26;92(20). pii: e00839-18. doi: 10.1128/JVI.00839-18. Print 2018 Oct 15.


Acidic pH Mediates Changes in Antigenic and Oligomeric Conformation of Herpes Simplex Virus gB and Is a Determinant of Cell-Specific Entry.

Weed DJ, Dollery SJ, Komala Sari T, Nicola AV.

J Virol. 2018 Aug 16;92(17). pii: e01034-18. doi: 10.1128/JVI.01034-18. Print 2018 Sep 1.


Herpes Simplex Virus 1 Envelope Cholesterol Facilitates Membrane Fusion.

Wudiri GA, Schneider SM, Nicola AV.

Front Microbiol. 2017 Dec 6;8:2383. doi: 10.3389/fmicb.2017.02383. eCollection 2017.


Herpes simplex virus Membrane Fusion.

Weed DJ, Nicola AV.

Adv Anat Embryol Cell Biol. 2017;223:29-47. doi: 10.1007/978-3-319-53168-7_2. Review.


Cellular Cholesterol Facilitates the Postentry Replication Cycle of Herpes Simplex Virus 1.

Wudiri GA, Nicola AV.

J Virol. 2017 Jun 26;91(14). pii: e00445-17. doi: 10.1128/JVI.00445-17. Print 2017 Jul 15.


Ovine Herpesvirus 2 Glycoproteins B, H, and L Are Sufficient for, and Viral Glycoprotein Ov8 Can Enhance, Cell-Cell Membrane Fusion.

AlHajri SM, Cunha CW, Nicola AV, Aguilar HC, Li H, Taus NS.

J Virol. 2017 Feb 28;91(6). pii: e02454-16. doi: 10.1128/JVI.02454-16. Print 2017 Mar 15.


Mildly Acidic pH Triggers an Irreversible Conformational Change in the Fusion Domain of Herpes Simplex Virus 1 Glycoprotein B and Inactivation of Viral Entry.

Weed DJ, Pritchard SM, Gonzalez F, Aguilar HC, Nicola AV.

J Virol. 2017 Feb 14;91(5). pii: e02123-16. doi: 10.1128/JVI.02123-16. Print 2017 Mar 1.


Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization.

Arnatt CK, Falls BA, Yuan Y, Raborg TJ, Masvekar RR, El-Hage N, Selley DE, Nicola AV, Knapp PE, Hauser KF, Zhang Y.

Bioorg Med Chem. 2016 Nov 15;24(22):5969-5987. doi: 10.1016/j.bmc.2016.09.059. Epub 2016 Sep 26.


Herpesvirus Entry into Host Cells Mediated by Endosomal Low pH.

Nicola AV.

Traffic. 2016 Sep;17(9):965-75. doi: 10.1111/tra.12408. Epub 2016 May 24. Review.


Multiple Novel Functions of Henipavirus O-glycans: The First O-glycan Functions Identified in the Paramyxovirus Family.

Stone JA, Nicola AV, Baum LG, Aguilar HC.

PLoS Pathog. 2016 Feb 11;12(2):e1005445. doi: 10.1371/journal.ppat.1005445. eCollection 2016 Feb.


Polyethylene glycol-mediated fusion of herpes simplex type 1 virions with the plasma membrane of cells that support endocytic entry.

Walker EB, Pritchard SM, Cunha CW, Aguilar HC, Nicola AV.

Virol J. 2015 Nov 16;12:190. doi: 10.1186/s12985-015-0423-0.


Abortion in a Mediterranean miniature donkey (Equus asinus) associated with a gammaherpesvirus similar to Equid herpesvirus 7.

LeCuyer TE, Rink A, Bradway DS, Evermann JF, Nicola AV, Baszler T, Haldorson GJ.

J Vet Diagn Invest. 2015 Nov;27(6):749-53. doi: 10.1177/1040638715611444. Epub 2015 Oct 13.


Widely Used Herpes Simplex Virus 1 ICP0 Deletion Mutant Strain dl1403 and Its Derivative Viruses Do Not Express Glycoprotein C Due to a Secondary Mutation in the gC Gene.

Cunha CW, Taylor KE, Pritchard SM, Delboy MG, Komala Sari T, Aguilar HC, Mossman KL, Nicola AV.

PLoS One. 2015 Jul 17;10(7):e0131129. doi: 10.1371/journal.pone.0131129. eCollection 2015.


Antibodies to ovine herpesvirus 2 glycoproteins decrease virus infectivity and prevent malignant catarrhal fever in rabbits.

Cunha CW, Knowles DP, Taus NS, O'Toole D, Nicola AV, Aguilar HC, Li H.

Vet Microbiol. 2015 Feb 25;175(2-4):349-55. doi: 10.1016/j.vetmic.2014.11.026. Epub 2014 Dec 9.


Nipah virus attachment glycoprotein stalk C-terminal region links receptor binding to fusion triggering.

Liu Q, Bradel-Tretheway B, Monreal AI, Saludes JP, Lu X, Nicola AV, Aguilar HC.

J Virol. 2015 Feb;89(3):1838-50. doi: 10.1128/JVI.02277-14. Epub 2014 Nov 26.


Nipah virion entry kinetics, composition, and conformational changes determined by enzymatic virus-like particles and new flow virometry tools.

Landowski M, Dabundo J, Liu Q, Nicola AV, Aguilar HC.

J Virol. 2014 Dec;88(24):14197-206. doi: 10.1128/JVI.01632-14. Epub 2014 Oct 1.


Molecular requirement for sterols in herpes simplex virus entry and infectivity.

Wudiri GA, Pritchard SM, Li H, Liu J, Aguilar HC, Gilk SD, Nicola AV.

J Virol. 2014 Dec;88(23):13918-22. doi: 10.1128/JVI.01615-14. Epub 2014 Sep 17.


Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry.

Liu Q, Stone JA, Bradel-Tretheway B, Dabundo J, Benavides Montano JA, Santos-Montanez J, Biering SB, Nicola AV, Iorio RM, Lu X, Aguilar HC.

PLoS Pathog. 2013;9(11):e1003770. doi: 10.1371/journal.ppat.1003770. Epub 2013 Nov 21.


Contributions of herpes simplex virus 1 envelope proteins to entry by endocytosis.

Komala Sari T, Pritchard SM, Cunha CW, Wudiri GA, Laws EI, Aguilar HC, Taus NS, Nicola AV.

J Virol. 2013 Dec;87(24):13922-6. doi: 10.1128/JVI.02500-13. Epub 2013 Oct 9.


Analysis of herpes simplex virion tegument ICP4 derived from infected cells and ICP4-expressing cells.

Pritchard SM, Cunha CW, Nicola AV.

PLoS One. 2013 Aug 6;8(8):e70889. doi: 10.1371/journal.pone.0070889. Print 2013.


Multiscale perspectives of virus entry via endocytosis.

Barrow E, Nicola AV, Liu J.

Virol J. 2013 Jun 5;10:177. doi: 10.1186/1743-422X-10-177. Review.


Virus entry by endocytosis.

Nicola AV, Aguilar HC, Mercer J, Ryckman B, Wiethoff CM.

Adv Virol. 2013;2013:469538. doi: 10.1155/2013/469538. Epub 2013 Apr 21. No abstract available.


Detection of receptor-induced glycoprotein conformational changes on enveloped virions by using confocal micro-Raman spectroscopy.

Lu X, Liu Q, Benavides-Montano JA, Nicola AV, Aston DE, Rasco BA, Aguilar HC.

J Virol. 2013 Mar;87(6):3130-42. doi: 10.1128/JVI.03220-12. Epub 2013 Jan 2.


Development of an in vivo system to measure antibody-blocking of ovine herpesvirus 2 entry.

Li H, Cunha CW, O'Toole D, Nicola AV, Knowles DP, Taus NS.

J Virol Methods. 2013 Mar;188(1-2):104-7. doi: 10.1016/j.jviromet.2012.12.008. Epub 2012 Dec 26.


Low-pH-dependent changes in the conformation and oligomeric state of the prefusion form of herpes simplex virus glycoprotein B are separable from fusion activity.

Dollery SJ, Wright CC, Johnson DC, Nicola AV.

J Virol. 2011 Oct;85(19):9964-73. doi: 10.1128/JVI.05291-11. Epub 2011 Aug 3.


A pre-immediate-early role for tegument ICP0 in the proteasome-dependent entry of herpes simplex virus.

Delboy MG, Nicola AV.

J Virol. 2011 Jun;85(12):5910-8. doi: 10.1128/JVI.00267-11. Epub 2011 Apr 6.


Reversible conformational change in herpes simplex virus glycoprotein B with fusion-from-without activity is triggered by mildly acidic pH.

Siekavizza-Robles CR, Dollery SJ, Nicola AV.

Virol J. 2010 Dec 1;7:352. doi: 10.1186/1743-422X-7-352.


Low pH-induced conformational change in herpes simplex virus glycoprotein B.

Dollery SJ, Delboy MG, Nicola AV.

J Virol. 2010 Apr;84(8):3759-66. doi: 10.1128/JVI.02573-09. Epub 2010 Feb 10.


Role of the UL45 protein in herpes simplex virus entry via low pH-dependent endocytosis and its relationship to the conformation and function of glycoprotein B.

Dollery SJ, Lane KD, Delboy MG, Roller DG, Nicola AV.

Virus Res. 2010 Apr;149(1):115-8. doi: 10.1016/j.virusres.2010.01.004. Epub 2010 Jan 18.


Herpes simplex virus tegument ICP0 is capsid associated, and its E3 ubiquitin ligase domain is important for incorporation into virions.

Delboy MG, Siekavizza-Robles CR, Nicola AV.

J Virol. 2010 Feb;84(3):1637-40. doi: 10.1128/JVI.02041-09. Epub 2009 Nov 11.


Structure-function analysis of herpes simplex virus glycoprotein B with fusion-from-without activity.

Roller DG, Dollery SJ, Doyle JL, Nicola AV.

Virology. 2008 Dec 20;382(2):207-16. doi: 10.1016/j.virol.2008.09.015. Epub 2008 Oct 23.


Cellular proteasome activity facilitates herpes simplex virus entry at a postpenetration step.

Delboy MG, Roller DG, Nicola AV.

J Virol. 2008 Apr;82(7):3381-90. doi: 10.1128/JVI.02296-07. Epub 2008 Jan 30.


Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1.

Milne RS, Nicola AV, Whitbeck JC, Eisenberg RJ, Cohen GH.

J Virol. 2005 Jun;79(11):6655-63.


Co-translational folding of an alphavirus capsid protein in the cytosol of living cells.

Nicola AV, Chen W, Helenius A.

Nat Cell Biol. 1999 Oct;1(6):341-5.


Herpes simplex virus glycoprotein D can bind to poliovirus receptor-related protein 1 or herpesvirus entry mediator, two structurally unrelated mediators of virus entry.

Krummenacher C, Nicola AV, Whitbeck JC, Lou H, Hou W, Lambris JD, Geraghty RJ, Spear PG, Cohen GH, Eisenberg RJ.

J Virol. 1998 Sep;72(9):7064-74.


Functional region IV of glycoprotein D from herpes simplex virus modulates glycoprotein binding to the herpesvirus entry mediator.

Rux AH, Willis SH, Nicola AV, Hou W, Peng C, Lou H, Cohen GH, Eisenberg RJ.

J Virol. 1998 Sep;72(9):7091-8.


Examination of the kinetics of herpes simplex virus glycoprotein D binding to the herpesvirus entry mediator, using surface plasmon resonance.

Willis SH, Rux AH, Peng C, Whitbeck JC, Nicola AV, Lou H, Hou W, Salvador L, Eisenberg RJ, Cohen GH.

J Virol. 1998 Jul;72(7):5937-47.


Monoclonal antibodies to distinct sites on herpes simplex virus (HSV) glycoprotein D block HSV binding to HVEM.

Nicola AV, Ponce de Leon M, Xu R, Hou W, Whitbeck JC, Krummenacher C, Montgomery RI, Spear PG, Eisenberg RJ, Cohen GH.

J Virol. 1998 May;72(5):3595-601.


Expression and Purification of Secreted Forms of HSV Glycoproteins from Baculovirus-Infected Insect Cells.

Willis SH, Peng C, Leon MP, Nicola AV, Rux AH, Cohen GH, Eisenberg RJ.

Methods Mol Med. 1998;10:131-56. doi: 10.1385/0-89603-347-3:131.


Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry.

Whitbeck JC, Peng C, Lou H, Xu R, Willis SH, Ponce de Leon M, Peng T, Nicola AV, Montgomery RI, Warner MS, Soulika AM, Spruce LA, Moore WT, Lambris JD, Spear PG, Cohen GH, Eisenberg RJ.

J Virol. 1997 Aug;71(8):6083-93.


Structure-function analysis of soluble forms of herpes simplex virus glycoprotein D.

Nicola AV, Willis SH, Naidoo NN, Eisenberg RJ, Cohen GH.

J Virol. 1996 Jun;70(6):3815-22.

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