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Myocardial Injury After Ischemia/Reperfusion Is Attenuated By Pharmacological Galectin-3 Inhibition.

Ibarrola J, Matilla L, Martínez-Martínez E, Gueret A, Fernández-Celis A, Henry JP, Nicol L, Jaisser F, Mulder P, Ouvrard-Pascaud A, López-Andrés N.

Sci Rep. 2019 Jul 3;9(1):9607. doi: 10.1038/s41598-019-46119-6.


Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF.

Mills R, Mathur A, Nicol LM, Walker JJ, Przybylski AA, Mackinnon AC, Howie SEM, Wallace WAH, Dransfield I, Hirani N.

J Immunol Res. 2019 Apr 11;2019:1845128. doi: 10.1155/2019/1845128. eCollection 2019.


Alterations in non-type I collagen biomarkers in osteogenesis imperfecta.

Nicol L, Morar P, Wang Y, Henriksen K, Sun S, Karsdal M, Smith R, Nagamani SCS, Shapiro J, Lee B, Orwoll E.

Bone. 2019 Mar;120:70-74. doi: 10.1016/j.bone.2018.09.024. Epub 2018 Oct 2.


Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations.

Kasper E, Angot E, Colasse E, Nicol L, Sabourin JC, Adriouch S, Lacoume Y, Charbonnier C, Raad S, Frebourg T, Flaman JM, Bougeard G.

Eur J Cancer. 2018 Sep;101:254-262. doi: 10.1016/j.ejca.2018.06.011. Epub 2018 Jul 30.


The IL-1β Antibody Gevokizumab Limits Cardiac Remodeling and Coronary Dysfunction in Rats With Heart Failure.

Harouki N, Nicol L, Remy-Jouet I, Henry JP, Dumesnil A, Lejeune A, Renet S, Golding F, Djerada Z, Wecker D, Bolduc V, Bouly M, Roussel J, Richard V, Mulder P.

JACC Basic Transl Sci. 2017 Aug 28;2(4):418-430. doi: 10.1016/j.jacbts.2017.06.005. eCollection 2017 Aug.


Short- and long-term administration of the non-steroidal mineralocorticoid receptor antagonist finerenone opposes metabolic syndrome-related cardio-renal dysfunction.

Lachaux M, Barrera-Chimal J, Nicol L, Rémy-Jouet I, Renet S, Dumesnil A, Wecker D, Richard V, Kolkhof P, Jaisser F, Ouvrard-Pascaud A, Mulder P.

Diabetes Obes Metab. 2018 Oct;20(10):2399-2407. doi: 10.1111/dom.13393. Epub 2018 Jun 27.


Effects of Iodized Salt and Iodine Supplements on Prenatal and Postnatal Growth: A Systematic Review.

Farebrother J, Naude CE, Nicol L, Sang Z, Yang Z, Jooste PL, Andersson M, Zimmermann MB.

Adv Nutr. 2018 May 1;9(3):219-237. doi: 10.1093/advances/nmy009. Erratum in: Adv Nutr. 2018 Sep 1;9(5):654.


Central inhibition of granulocyte-macrophage colony-stimulating factor is analgesic in experimental neuropathic pain.

Nicol LSC, Thornton P, Hatcher JP, Glover CP, Webster CI, Burrell M, Hammett K, Jones CA, Sleeman MA, Billinton A, Chessell I.

Pain. 2018 Mar;159(3):550-559. doi: 10.1097/j.pain.0000000000001130.


Value of magnetic resonance imaging for evaluating muscle inflammation: insights from a new mouse model of myositis.

Bourdenet G, Dubourg B, Nicol L, Mulder P, Martinet J, Allenbach Y, Boitard C, Boyer O.

Neuropathol Appl Neurobiol. 2018 Aug;44(5):537-540. doi: 10.1111/nan.12457. No abstract available.


Serum Sclerostin Levels in Adults With Osteogenesis Imperfecta: Comparison With Normal Individuals and Response to Teriparatide Therapy.

Nicol L, Wang Y, Smith R, Sloan J, Nagamani SC, Shapiro J, Lee B, Orwoll E.

J Bone Miner Res. 2018 Feb;33(2):307-315. doi: 10.1002/jbmr.3312. Epub 2017 Dec 7.


TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.

Thornton P, Sevalle J, Deery MJ, Fraser G, Zhou Y, Ståhl S, Franssen EH, Dodd RB, Qamar S, Gomez Perez-Nievas B, Nicol LS, Eketjäll S, Revell J, Jones C, Billinton A, St George-Hyslop PH, Chessell I, Crowther DC.

EMBO Mol Med. 2017 Oct;9(10):1366-1378. doi: 10.15252/emmm.201707673.


A candidate gene approach to study nematode resistance traits in naturally infected sheep.

Wilkie H, Riggio V, Matika O, Nicol L, Watt KA, Sinclair R, Sparks AM, Nussey DH, Pemberton JM, Houston RD, Hopkins J.

Vet Parasitol. 2017 Aug 30;243:71-74. doi: 10.1016/j.vetpar.2017.06.010. Epub 2017 Jun 10.


Second- and Third-line Antiretroviral Therapy for Children and Adolescents: A Scoping Review.

Lazarus E, Nicol S, Frigati L, Penazzato M, Cotton MF, Centeno-Tablante E, Violari A, Nicol L.

Pediatr Infect Dis J. 2017 May;36(5):492-499. doi: 10.1097/INF.0000000000001481. Review.


Mucosal Expression of T Cell Gene Variants Is Associated with Differential Resistance to Teladorsagia circumcincta.

Wilkie H, Nicol L, Gossner A, Hopkins J.

PLoS One. 2016 Dec 14;11(12):e0168194. doi: 10.1371/journal.pone.0168194. eCollection 2016.


Assessment of endothelial damage and cardiac injury in a mouse model mimicking thrombotic thrombocytopenic purpura.

Le Besnerais M, Favre J, Denis CV, Mulder P, Martinet J, Nicol L, Levesque H, Veyradier A, Kopić A, Motto DG, Coppo P, Richard V, Benhamou Y.

J Thromb Haemost. 2016 Oct;14(10):1917-1930. doi: 10.1111/jth.13439. Epub 2016 Sep 28.


Variations in T cell transcription factor gene structure and expression associated with the two disease forms of sheep paratuberculosis.

Nicol L, Wilkie H, Gossner A, Watkins C, Dalziel R, Hopkins J.

Vet Res. 2016 Aug 17;47(1):83. doi: 10.1186/s13567-016-0368-3.


Simulation-based education: understanding the socio-cultural complexity of a surgical training 'boot camp'.

Cleland J, Walker KG, Gale M, Nicol LG.

Med Educ. 2016 Aug;50(8):829-41. doi: 10.1111/medu.13064.


Selective Vascular Endothelial Protection Reduces Cardiac Dysfunction in Chronic Heart Failure.

Maupoint J, Besnier M, Gomez E, Bouhzam N, Henry JP, Boyer O, Nicol L, Mulder P, Martinet J, Richard V.

Circ Heart Fail. 2016 Apr;9(4):e002895. doi: 10.1161/CIRCHEARTFAILURE.115.002895. Epub 2016 Apr 8.


Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction.

Henri O, Pouehe C, Houssari M, Galas L, Nicol L, Edwards-Lévy F, Henry JP, Dumesnil A, Boukhalfa I, Banquet S, Schapman D, Thuillez C, Richard V, Mulder P, Brakenhielm E.

Circulation. 2016 Apr 12;133(15):1484-97; discussion 1497. doi: 10.1161/CIRCULATIONAHA.115.020143. Epub 2016 Mar 1.


Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction.

Gueret A, Harouki N, Favre J, Galmiche G, Nicol L, Henry JP, Besnier M, Thuillez C, Richard V, Kolkhof P, Mulder P, Jaisser F, Ouvrard-Pascaud A.

Hypertension. 2016 Apr;67(4):717-23. doi: 10.1161/HYPERTENSIONAHA.115.06709. Epub 2016 Feb 22.


Variations in IL-23 and IL-25 receptor gene structure, sequence and expression associated with the two disease forms of sheep paratuberculosis.

Nicol L, Gossner A, Watkins C, Chianini F, Dalziel R, Hopkins J.

Vet Res. 2016 Feb 9;47:27. doi: 10.1186/s13567-016-0314-4.


Iodised salt and iodine supplements for prenatal and postnatal growth: a rapid scoping of existing systematic reviews.

Farebrother J, Naude CE, Nicol L, Andersson M, Zimmermann MB.

Nutr J. 2015 Sep 2;14:89. doi: 10.1186/s12937-015-0079-z. Review.


Selective Heart Rate Reduction Improves Metabolic Syndrome-related Left Ventricular Diastolic Dysfunction.

Merabet N, Fang Y, Nicol L, Monteil C, Rémy-Jouet I, Henry JP, Wecker D, Le Bouter-Banon S, Roussel J, Richard V, Thuillez C, Mulder P.

J Cardiovasc Pharmacol. 2015 Oct;66(4):399-408. doi: 10.1097/FJC.0000000000000294.


The role of G-protein receptor 84 in experimental neuropathic pain.

Nicol LS, Dawes JM, La Russa F, Didangelos A, Clark AK, Gentry C, Grist J, Davies JB, Malcangio M, McMahon SB.

J Neurosci. 2015 Jun 10;35(23):8959-69. doi: 10.1523/JNEUROSCI.3558-14.2015.


Systematic review of the effects of iodised salt and iodine supplements on prenatal and postnatal growth: study protocol.

Farebrother J, Naude CE, Nicol L, Sang Z, Yang Z, Andersson M, Jooste PL, Zimmermann MB.

BMJ Open. 2015 Apr 23;5(4):e007238. doi: 10.1136/bmjopen-2014-007238.


Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS).

Nicol LM, Rowlands DS, Fazakerly R, Kellett J.

Eur J Appl Physiol. 2015 Aug;115(8):1769-77. doi: 10.1007/s00421-015-3152-6. Epub 2015 Mar 21.


Six cases of silicosis: implications for health surveillance of stonemasons.

Nicol LM, McFarlane PA, Hirani N, Reid PT.

Occup Med (Lond). 2015 Apr;65(3):220-5. doi: 10.1093/occmed/kqu209. Epub 2015 Mar 4.


Soluble epoxide hydrolase inhibition improves coronary endothelial function and prevents the development of cardiac alterations in obese insulin-resistant mice.

Roche C, Besnier M, Cassel R, Harouki N, Coquerel D, Guerrot D, Nicol L, Loizon E, Remy-Jouet I, Morisseau C, Mulder P, Ouvrard-Pascaud A, Madec AM, Richard V, Bellien J.

Am J Physiol Heart Circ Physiol. 2015 May 1;308(9):H1020-9. doi: 10.1152/ajpheart.00465.2014. Epub 2015 Feb 27.


Response to: 'Driven to distraction and driving for excellence in ward round practice' by Pucher and Aggarwal.

Thomas I, Nicol L, Regan L, Cleland J, Maliepaard D, Clark L, Walker K, Duncan J.

BMJ Qual Saf. 2015 Apr;24(4):291-2. doi: 10.1136/bmjqs-2015-004014. Epub 2015 Feb 20. No abstract available.


Bone morphogenetic proteins are mediators of luteolysis in the human corpus luteum.

Nio-Kobayashi J, Trendell J, Giakoumelou S, Boswell L, Nicol L, Kudo M, Sakuragi N, Iwanaga T, Duncan WC.

Endocrinology. 2015 Apr;156(4):1494-503. doi: 10.1210/en.2014-1704. Epub 2015 Jan 30.


Driven to distraction: a prospective controlled study of a simulated ward round experience to improve patient safety teaching for medical students.

Thomas I, Nicol L, Regan L, Cleland J, Maliepaard D, Clark L, Walker K, Duncan J.

BMJ Qual Saf. 2015 Feb;24(2):154-61. doi: 10.1136/bmjqs-2014-003272. Epub 2014 Nov 24.


Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys.

Nicol LE, O'Brien TD, Dumesic DA, Grogan T, Tarantal AF, Abbott DH.

PLoS One. 2014 Sep 10;9(9):e106527. doi: 10.1371/journal.pone.0106527. eCollection 2014.


Magnetic resonance colonography for fibrosis assessment in rats with chronic colitis.

Melchior C, Loeuillard E, Marion-Letellier R, Nicol L, Mulder P, Guerin C, Bôle-Feysot C, Aziz M, Déchelotte P, Vera P, Savoye G, Savoye-Collet C.

PLoS One. 2014 Jul 7;9(7):e100921. doi: 10.1371/journal.pone.0100921. eCollection 2014.


Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B-deficient mice.

Besnier M, Galaup A, Nicol L, Henry JP, Coquerel D, Gueret A, Mulder P, Brakenhielm E, Thuillez C, Germain S, Richard V, Ouvrard-Pascaud A.

FASEB J. 2014 Aug;28(8):3351-61. doi: 10.1096/fj.13-245753. Epub 2014 Apr 23.


Providing a specialty trainee teaching programme over long distances.

MacDonald E, Nicol L, Ahmed I.

Clin Teach. 2013 Dec;10(6):374-8. doi: 10.1111/tct.12032.


Complications of stomas: their aetiology and management.

Watson AJ, Nicol L, Donaldson S, Fraser C, Silversides A.

Br J Community Nurs. 2013 Mar;18(3):111-2, 114, 116.


MR relaxometry and perfusion of the myocardium in spontaneously hypertensive rat: correlation with histopathology and effect of anti-hypertensive therapy.

Caudron J, Mulder P, Nicol L, Richard V, Thuillez C, Dacher JN.

Eur Radiol. 2013 Jul;23(7):1871-81. doi: 10.1007/s00330-013-2801-6. Epub 2013 Apr 17.


Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates.

Nicol LE, Grant WF, Comstock SM, Nguyen ML, Smith MS, Grove KL, Marks DL.

J Endocrinol. 2013 Apr 15;217(2):207-13. doi: 10.1530/JOE-12-0424. Print 2013 May. Erratum in: J Endocrinol. 2013 Jul;218(1):X1. Grant, W R [corrected to Grant, W F].


Nonhuman primate models of polycystic ovary syndrome.

Abbott DH, Nicol LE, Levine JE, Xu N, Goodarzi MO, Dumesic DA.

Mol Cell Endocrinol. 2013 Jul 5;373(1-2):21-8. doi: 10.1016/j.mce.2013.01.013. Epub 2013 Jan 29. Review.


Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques.

Grant WF, Nicol LE, Thorn SR, Grove KL, Friedman JE, Marks DL.

PLoS One. 2012;7(10):e48119. doi: 10.1371/journal.pone.0048119. Epub 2012 Oct 30.


Magnetic resonance colonography in rats with TNBS-induced colitis: a feasibility and validation study.

Charpentier C, Marion-Letellier R, Savoye G, Nicol L, Mulder P, Aziz M, Vera P, Déchelotte P, Savoye-Collet C.

Inflamm Bowel Dis. 2012 Oct;18(10):1940-9. doi: 10.1002/ibd.22897. Epub 2012 Jan 19.


Presence of SNPs in GDF9 mRNA of Iranian Afshari Sheep.

Eghbalsaied S, Ghaedi K, Shahmoradi S, Pirestani A, Amini H, Saiedi T, Nicol L, McNeilly A.

Int J Fertil Steril. 2012 Jan;5(4):225-30. Epub 2012 Mar 20.


Soluble epoxide hydrolase inhibition improves myocardial perfusion and function in experimental heart failure.

Merabet N, Bellien J, Glevarec E, Nicol L, Lucas D, Remy-Jouet I, Bounoure F, Dreano Y, Wecker D, Thuillez C, Mulder P.

J Mol Cell Cardiol. 2012 Mar;52(3):660-6. doi: 10.1016/j.yjmcc.2011.11.015. Epub 2011 Dec 6.


Arteriogenic therapy by intramyocardial sustained delivery of a novel growth factor combination prevents chronic heart failure.

Banquet S, Gomez E, Nicol L, Edwards-Lévy F, Henry JP, Cao R, Schapman D, Dautreaux B, Lallemand F, Bauer F, Cao Y, Thuillez C, Mulder P, Richard V, Brakenhielm E.

Circulation. 2011 Aug 30;124(9):1059-69. doi: 10.1161/CIRCULATIONAHA.110.010264. Epub 2011 Aug 8.


Improvement of left ventricular diastolic function induced by β-blockade: a comparison between nebivolol and metoprolol.

Fang Y, Nicol L, Harouki N, Monteil C, Wecker D, Debunne M, Bauer F, Lallemand F, Richard V, Thuillez C, Mulder P.

J Mol Cell Cardiol. 2011 Aug;51(2):168-76. doi: 10.1016/j.yjmcc.2011.05.012. Epub 2011 May 24.


Amyl nitrite induced cerebral and coronary vasospasm.

Nicol LM, Mills NL, Starkey IR.

QJM. 2011 Jan;104(1):83-4. doi: 10.1093/qjmed/hcq162. Epub 2010 Sep 15. No abstract available.


Abnormal colonic motility: a possible association with urge fecal incontinence.

Rodger CJ, Nicol L, Anderson JH, McKee RF, Finlay IG.

Dis Colon Rectum. 2010 Apr;53(4):409-13. doi: 10.1007/DCR.0b013e3181cc55cc.


Homozygosity for a single base-pair mutation in the oocyte-specific GDF9 gene results in sterility in Thoka sheep.

Nicol L, Bishop SC, Pong-Wong R, Bendixen C, Holm LE, Rhind SM, McNeilly AS.

Reproduction. 2009 Dec;138(6):921-33. doi: 10.1530/REP-09-0193. Epub 2009 Aug 27.


Neonatal estrogenic effects upon the male rat pituitary: early gonadotrophin attenuation precedes long-term recovery.

Martin B, Maudsley S, McNeilly J, Nicol L, Crawford J, Millar M, Sharpe RM, McNeilly AS.

Neuromolecular Med. 2009;11(2):76-86. doi: 10.1007/s12017-009-8075-0. Epub 2009 Jun 30.


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