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Items: 44

1.

Using tree-based methods for detection of gene-gene interactions in the presence of a polygenic signal: simulation study with application to educational attainment in the Generation Scotland Cohort Study.

Meijsen JJ, Rammos A, Campbell A, Hayward C, Porteous DJ, Deary IJ, Marioni RE, Nicodemus KK.

Bioinformatics. 2018 Jun 19. doi: 10.1093/bioinformatics/bty462. [Epub ahead of print]

PMID:
29931044
2.

Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study.

Meijsen JJ, Campbell A, Hayward C, Porteous DJ, Deary IJ, Marioni RE, Nicodemus KK.

Transl Psychiatry. 2018 Mar 13;8(1):63. doi: 10.1038/s41398-018-0111-0.

3.

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).

Wigmore EM, Clarke TK, Howard DM, Adams MJ, Hall LS, Zeng Y, Gibson J, Davies G, Fernandez-Pujals AM, Thomson PA, Hayward C, Smith BH, Hocking LJ, Padmanabhan S, Deary IJ, Porteous DJ, Nicodemus KK, McIntosh AM.

Transl Psychiatry. 2017 Aug 15;7(8):e1205. doi: 10.1038/tp.2017.148.

4.

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA Jr, Bergen SE, Bertalan M, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Bulik-Sullivan B, Byerley W, Cahn W, Cai G, Cairns MJ, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Cheng W, Cloninger CR, Cohen D, Cormican P, Craddock N, Crespo-Facorro B, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, DeLisi LE, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Eichhammer P, Eriksson J, Escott-Price V, Essioux L, Fanous AH, Farh KH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedman JI, Forstner AJ, Fromer M, Genovese G, Georgieva L, Gershon ES, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, Gratten J, de Haan L, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Huang H, Ikeda M, Joa I, Kähler AK, Kahn RS, Kalaydjieva L, Karjalainen J, Kavanagh D, Keller MC, Kelly BJ, Kennedy JL, Kim Y, Knowles JA, Konte B, Laurent C, Lee P, Lee SH, Legge SE, Lerer B, Levy DL, Liang KY, Lieberman J, Lönnqvist J, Loughland CM, Magnusson PKE, Maher BS, Maier W, Mallet J, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Müller-Myhsok B, Murphy KC, Murray RM, Myin-Germeys I, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nisenbaum L, Nordin A, O'Callaghan E, O'Dushlaine C, Oh SY, Olincy A, Olsen L, O'Neill FA, Van Os J, Pantelis C, Papadimitriou GN, Parkhomenko E, Pato MT, Paunio T; Psychosis Endophenotypes International Consortium, Perkins DO, Pers TH, Pietiläinen O, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Savitz A, Schall U, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Silverman JM, Smoller JW, Söderman E, Spencer CCA, Stahl EA, Strengman E, Strohmaier J, Stroup TS, Suvisaari J, Svrakic DM, Szatkiewicz JP, Thirumalai S, Tooney PA, Veijola J, Visscher PM, Waddington J, Walsh D, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wormley BK, Wray NR, Wu JQ, Zai CC, Adolfsson R, Andreassen OA, Blackwood DHR, Bramon E, Buxbaum JD, Cichon S, Collier DA, Corvin A, Daly MJ, Darvasi A, Domenici E, Esko T, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Levinson DF, Li QS, McCarroll SA, McQuillin A, Moran JL, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sklar P, St Clair D, Walters JTR, Werge T, Sullivan PF, O'Donovan MC, Scherer SW, Neale BM, Sebat J; CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.

Nat Genet. 2017 Jan;49(1):27-35. doi: 10.1038/ng.3725. Epub 2016 Nov 21. Erratum in: Nat Genet. 2017 Sep 27;49(10 ):1558. Nat Genet. 2017 Mar 30;49(4):651.

5.

Data science for mental health: a UK perspective on a global challenge.

McIntosh AM, Stewart R, John A, Smith DJ, Davis K, Sudlow C, Corvin A, Nicodemus KK, Kingdon D, Hassan L, Hotopf M, Lawrie SM, Russ TC, Geddes JR, Wolpert M, Wölbert E, Porteous DJ; MQ Data Science Group.

Lancet Psychiatry. 2016 Oct;3(10):993-998. doi: 10.1016/S2215-0366(16)30089-X. Review.

PMID:
27692269
6.

An examination of the language construct in NIMH's research domain criteria: Time for reconceptualization!

Elvevåg B, Cohen AS, Wolters MK, Whalley HC, Gountouna VE, Kuznetsova KA, Watson AR, Nicodemus KK.

Am J Med Genet B Neuropsychiatr Genet. 2016 Sep;171(6):904-19. doi: 10.1002/ajmg.b.32438. Epub 2016 Mar 10. Review.

7.

Variability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway.

Nicodemus KK, Hargreaves A, Morris D, Anney R; Schizophrenia Psychiatric Genome-wide Association Study (GWAS) Consortium; Wellcome Trust Case Control Consortium 2, Gill M, Corvin A, Donohoe G.

JAMA Psychiatry. 2014 Jul 1;71(7):778-785. doi: 10.1001/jamapsychiatry.2014.528.

8.

Category fluency, latent semantic analysis and schizophrenia: a candidate gene approach.

Nicodemus KK, Elvevåg B, Foltz PW, Rosenstein M, Diaz-Asper C, Weinberger DR.

Cortex. 2014 Jun;55:182-91. doi: 10.1016/j.cortex.2013.12.004. Epub 2013 Dec 20.

9.

The one and the many: effects of the cell adhesion molecule pathway on neuropsychological function in psychosis.

Hargreaves A, Anney R, O'Dushlaine C, Nicodemus KK; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); Wellcome Trust Case Control Consortium 2, Gill M, Corvin A, Morris D, Donohoe G.

Psychol Med. 2014 Jul;44(10):2177-87. doi: 10.1017/S0033291713002663. Epub 2013 Nov 28.

PMID:
24284030
10.

Letter to the editor: on the stability and ranking of predictors from random forest variable importance measures.

Nicodemus KK.

Brief Bioinform. 2011 Jul;12(4):369-73. doi: 10.1093/bib/bbr016. Epub 2011 Apr 15.

11.

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.

Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR.

Arch Gen Psychiatry. 2010 Oct;67(10):991-1001. doi: 10.1001/archgenpsychiatry.2010.117.

12.

Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe.

Evseeva I, Nicodemus KK, Bonilla C, Tonks S, Bodmer WF.

Eur J Hum Genet. 2010 Aug;18(8):924-32. doi: 10.1038/ejhg.2010.32. Epub 2010 Mar 31.

13.

The behaviour of random forest permutation-based variable importance measures under predictor correlation.

Nicodemus KK, Malley JD, Strobl C, Ziegler A.

BMC Bioinformatics. 2010 Feb 27;11:110. doi: 10.1186/1471-2105-11-110.

14.

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.

Nicodemus KK, Callicott JH, Higier RG, Luna A, Nixon DC, Lipska BK, Vakkalanka R, Giegling I, Rujescu D, St Clair D, Muglia P, Shugart YY, Weinberger DR.

Hum Genet. 2010 Apr;127(4):441-52. doi: 10.1007/s00439-009-0782-y. Erratum in: Hum Genet. 2010 Apr;127(4):453-4.

PMID:
20084519
15.

A 5' promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression.

Nicodemus KK, Law AJ, Luna A, Vakkalanka R, Straub RE, Kleinman JE, Weinberger DR.

Mol Psychiatry. 2009 Aug;14(8):741-3. doi: 10.1038/mp.2008.150. No abstract available.

16.

Predictor correlation impacts machine learning algorithms: implications for genomic studies.

Nicodemus KK, Malley JD.

Bioinformatics. 2009 Aug 1;25(15):1884-90. doi: 10.1093/bioinformatics/btp331. Epub 2009 May 21.

PMID:
19460890
17.

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia.

Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V, Lipska BK, Hyde TM, Song J, Rujescu D, Giegling I, Mayilyan K, Proust MJ, Soghoyan A, Caforio G, Callicott JH, Bertolino A, Meyer-Lindenberg A, Chang J, Ji Y, Egan MF, Goldberg TE, Kleinman JE, Lu B, Weinberger DR.

Nat Med. 2009 May;15(5):509-18. doi: 10.1038/nm.1962. Epub 2009 May 3.

18.

Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function.

Kempf L, Nicodemus KK, Kolachana B, Vakkalanka R, Verchinski BA, Egan MF, Straub RE, Mattay VA, Callicott JH, Weinberger DR, Meyer-Lindenberg A.

PLoS Genet. 2008 Nov;4(11):e1000252. doi: 10.1371/journal.pgen.1000252. Epub 2008 Nov 7.

19.

Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans.

Tan HY, Nicodemus KK, Chen Q, Li Z, Brooke JK, Honea R, Kolachana BS, Straub RE, Meyer-Lindenberg A, Sei Y, Mattay VS, Callicott JH, Weinberger DR.

J Clin Invest. 2008 Jun;118(6):2200-8. doi: 10.1172/JCI34725.

20.

Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans.

Meyer-Lindenberg A, Kolachana B, Gold B, Olsh A, Nicodemus KK, Mattay V, Dean M, Weinberger DR.

Mol Psychiatry. 2009 Oct;14(10):968-75. doi: 10.1038/mp.2008.54. Epub 2008 May 20.

22.

The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia.

Matsumoto M, Straub RE, Marenco S, Nicodemus KK, Matsumoto S, Fujikawa A, Miyoshi S, Shobo M, Takahashi S, Yarimizu J, Yuri M, Hiramoto M, Morita S, Yokota H, Sasayama T, Terai K, Yoshino M, Miyake A, Callicott JH, Egan MF, Meyer-Lindenberg A, Kempf L, Honea R, Vakkalanka RK, Takasaki J, Kamohara M, Soga T, Hiyama H, Ishii H, Matsuo A, Nishimura S, Matsuoka N, Kobori M, Matsushime H, Katoh M, Furuichi K, Weinberger DR.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6133-8. doi: 10.1073/pnas.0710717105. Epub 2008 Apr 14.

23.

Catmap: case-control and TDT meta-analysis package.

Nicodemus KK.

BMC Bioinformatics. 2008 Feb 28;9:130. doi: 10.1186/1471-2105-9-130.

24.

False positives in imaging genetics.

Meyer-Lindenberg A, Nicodemus KK, Egan MF, Callicott JH, Mattay V, Weinberger DR.

Neuroimage. 2008 Apr 1;40(2):655-661. doi: 10.1016/j.neuroimage.2007.11.058. Epub 2007 Dec 15.

PMID:
18201908
25.

Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk.

Nicodemus KK, Marenco S, Batten AJ, Vakkalanka R, Egan MF, Straub RE, Weinberger DR.

Mol Psychiatry. 2008 Sep;13(9):873-7. doi: 10.1038/sj.mp.4002153. Epub 2008 Jan 15.

PMID:
18195713
26.

Data mining, neural nets, trees--problems 2 and 3 of Genetic Analysis Workshop 15.

Ziegler A, DeStefano AL, König IR, Bardel C, Brinza D, Bull S, Cai Z, Glaser B, Jiang W, Lee KE, Li CX, Li J, Li X, Majoram P, Meng Y, Nicodemus KK, Platt A, Schwarz DF, Shi W, Shugart YY, Stassen HH, Sun YV, Won S, Wang W, Wahba G, Zagaar UA, Zhao Z.

Genet Epidemiol. 2007;31 Suppl 1:S51-60.

PMID:
18046765
27.

snp.plotter: an R-based SNP/haplotype association and linkage disequilibrium plotting package.

Luna A, Nicodemus KK.

Bioinformatics. 2007 Mar 15;23(6):774-6. Epub 2007 Jan 18.

PMID:
17234637
29.

Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls.

Nicodemus KK, Luna A, Vakkalanka R, Goldberg T, Egan M, Straub RE, Weinberger DR.

Mol Psychiatry. 2006 Dec;11(12):1062-5. No abstract available. Erratum in: Mol Psychiatry. 2007 Sep;12(9):883.

PMID:
17130882
30.

Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia.

Nicodemus KK, Kolachana BS, Vakkalanka R, Straub RE, Giegling I, Egan MF, Rujescu D, Weinberger DR.

Hum Genet. 2007 Feb;120(6):889-906. Epub 2006 Sep 28.

PMID:
17006672
31.

A systematic review of vitamin D receptor gene polymorphisms and prostate cancer risk.

Berndt SI, Dodson JL, Huang WY, Nicodemus KK.

J Urol. 2006 May;175(5):1613-23.

PMID:
16600714
33.

Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios.

Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA, Steel G, Nestadt G, Liang KY, Huganir RL, Valle D, Pulver AE.

Am J Hum Genet. 2005 Dec;77(6):918-36. Epub 2005 Oct 28.

34.

Diabetes mellitus and subsite-specific colorectal cancer risks in the Iowa Women's Health Study.

Limburg PJ, Anderson KE, Johnson TW, Jacobs DR Jr, Lazovich D, Hong CP, Nicodemus KK, Folsom AR.

Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):133-7.

35.

Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.

Nicodemus KK, Stenger JE, Schmechel DE, Welsh-Bohmer KA, Saunders AM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA, Martin ER.

Neurogenetics. 2004 Dec;5(4):201-8. Epub 2004 Sep 29.

PMID:
15455263
36.

Analysis of European mitochondrial haplogroups with Alzheimer disease risk.

van der Walt JM, Dementieva YA, Martin ER, Scott WK, Nicodemus KK, Kroner CC, Welsh-Bohmer KA, Saunders AM, Roses AD, Small GW, Schmechel DE, Murali Doraiswamy P, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA.

Neurosci Lett. 2004 Jul 15;365(1):28-32.

PMID:
15234467
37.
38.

The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.

Oliveira SA, Martin ER, Scott WK, Nicodemus KK, Small GW, Schmechel DE, Doraiswamy PM, Roses AD, Saunders AM, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA.

Neurosci Lett. 2003 Aug 28;347(3):143-6.

PMID:
12875906
39.

Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease.

van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH Jr, Goetz CG, Small GW, Mastaglia F, Stajich JM, McLaurin AC, Middleton LT, Scott BL, Schmechel DE, Pericak-Vance MA, Vance JM.

Am J Hum Genet. 2003 Apr;72(4):804-11. Epub 2003 Feb 28.

40.

Age at onset in two common neurodegenerative diseases is genetically controlled.

Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA Jr, Goetz CG, Mastaglia F, Stajich JM, Gibson RA, Middleton LT, Saunders AM, Scott BL, Small GW, Nicodemus KK, Reed AD, Schmechel DE, Welsh-Bohmer KA, Conneally PM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA.

Am J Hum Genet. 2002 Apr;70(4):985-93. Epub 2002 Mar 1.

41.

Whole and refined grain intake and risk of incident postmenopausal breast cancer (United States).

Nicodemus KK, Jacobs DR Jr, Folsom AR.

Cancer Causes Control. 2001 Dec;12(10):917-25.

PMID:
11808711
42.

Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women.

Nicodemus KK, Folsom AR; Iowa Women's Health Study.

Diabetes Care. 2001 Jul;24(7):1192-7.

PMID:
11423501
43.

Menstrual history and risk of hip fractures in postmenopausal women. The Iowa Women's Health Study.

Nicodemus KK, Folsom AR, Anderson KE.

Am J Epidemiol. 2001 Feb 1;153(3):251-5.

PMID:
11157412
44.

Characteristics of research volunteers for inpatient cocaine studies: focus on selection bias.

Sofuoglu M, Dudish-Poulsen S, Nicodemus KK, Babb DA, Hatsukami DK.

Addict Behav. 2000 Sep-Oct;25(5):785-90.

PMID:
11023020

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