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Items: 14


Folding pathway of an Ig domain is conserved on and off the ribosome.

Tian P, Steward A, Kudva R, Su T, Shilling PJ, Nickson AA, Hollins JJ, Beckmann R, von Heijne G, Clarke J, Best RB.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11284-E11293. doi: 10.1073/pnas.1810523115. Epub 2018 Nov 9.


Cotranslational folding of spectrin domains via partially structured states.

Nilsson OB, Nickson AA, Hollins JJ, Wickles S, Steward A, Beckmann R, von Heijne G, Clarke J.

Nat Struct Mol Biol. 2017 Mar;24(3):221-225. doi: 10.1038/nsmb.3355. Epub 2017 Jan 23.


Smoothing a rugged protein folding landscape by sequence-based redesign.

Porebski BT, Keleher S, Hollins JJ, Nickson AA, Marijanovic EM, Borg NA, Costa MG, Pearce MA, Dai W, Zhu L, Irving JA, Hoke DE, Kass I, Whisstock JC, Bottomley SP, Webb GI, McGowan S, Buckle AM.

Sci Rep. 2016 Sep 26;6:33958. doi: 10.1038/srep33958.


Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.

Porebski BT, Nickson AA, Hoke DE, Hunter MR, Zhu L, McGowan S, Webb GI, Buckle AM.

Protein Eng Des Sel. 2015 Mar;28(3):67-78. doi: 10.1093/protein/gzv002.


A mechanistic model for amorphous protein aggregation of immunoglobulin-like domains.

Borgia MB, Nickson AA, Clarke J, Hounslow MJ.

J Am Chem Soc. 2013 May 1;135(17):6456-64. doi: 10.1021/ja308852b. Epub 2013 Apr 18.


Take home lessons from studies of related proteins.

Nickson AA, Wensley BG, Clarke J.

Curr Opin Struct Biol. 2013 Feb;23(1):66-74. doi: 10.1016/ Epub 2012 Dec 20. Review.


Understanding pathogenic single-nucleotide polymorphisms in multidomain proteins--studies of isolated domains are not enough.

Randles LG, Dawes GJ, Wensley BG, Steward A, Nickson AA, Clarke J.

FEBS J. 2013 Feb;280(4):1018-27. doi: 10.1111/febs.12094. Epub 2013 Jan 16.


The morphology of decorated amyloid fibers is controlled by the conformation and position of the displayed protein.

Forman CJ, Nickson AA, Anthony-Cahill SJ, Baldwin AJ, Kaggwa G, Feber U, Sheikh K, Jarvis SP, Barker PD.

ACS Nano. 2012 Feb 28;6(2):1332-46. doi: 10.1021/nn204140a. Epub 2012 Feb 14.


Affinity maturation of phage display antibody populations using ribosome display.

Groves MA, Nickson AA.

Methods Mol Biol. 2012;805:163-90. doi: 10.1007/978-1-61779-379-0_10.


What lessons can be learned from studying the folding of homologous proteins?

Nickson AA, Clarke J.

Methods. 2010 Sep;52(1):38-50. doi: 10.1016/j.ymeth.2010.06.003. Epub 2010 Jun 4. Review.


Studying the folding of multidomain proteins.

Batey S, Nickson AA, Clarke J.

HFSP J. 2008 Dec;2(6):365-77. doi: 10.2976/1.2991513. Epub 2008 Oct 15.


Folding of a LysM domain: entropy-enthalpy compensation in the transition state of an ideal two-state folder.

Nickson AA, Stoll KE, Clarke J.

J Mol Biol. 2008 Jul 11;380(3):557-69. doi: 10.1016/j.jmb.2008.05.020. Epub 2008 May 17.


The folding and evolution of multidomain proteins.

Han JH, Batey S, Nickson AA, Teichmann SA, Clarke J.

Nat Rev Mol Cell Biol. 2007 Apr;8(4):319-30. doi: 10.1038/nrm2144. Epub 2007 Mar 14. Review.


BPPred: a Web-based computational tool for predicting biophysical parameters of proteins.

Geierhaas CD, Nickson AA, Lindorff-Larsen K, Clarke J, Vendruscolo M.

Protein Sci. 2007 Jan;16(1):125-34. Epub 2006 Nov 22.

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