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Items: 46

1.

Long-range DNA interactions at the IL-1/IL-36/IL-37 gene cluster (2q13) are induced by activation of monocytes.

Sharaf N, Nicklin MJ, di Giovine FS.

Cytokine. 2014 Jul;68(1):16-22. doi: 10.1016/j.cyto.2014.03.002. Epub 2014 Apr 16.

PMID:
24787052
2.

Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration.

Phillips KL, Jordan-Mahy N, Nicklin MJ, Le Maitre CL.

Ann Rheum Dis. 2013 Nov;72(11):1860-7. doi: 10.1136/annrheumdis-2012-202266. Epub 2013 Feb 9.

PMID:
23396662
3.

Intracellular function of interleukin-1 receptor antagonist in ischemic cardiomyocytes.

Vecile E, Dobrina A, Salloum FN, Van Tassell BW, Falcione A, Gustini E, Secchiero S, Crovella S, Sinagra G, Finato N, Nicklin MJ, Abbate A.

PLoS One. 2013;8(1):e53265. doi: 10.1371/journal.pone.0053265. Epub 2013 Jan 8.

4.

Impact of IL-1 signalling on experimental uveitis and arthritis.

Planck SR, Woods A, Clowers JS, Nicklin MJ, Rosenbaum JT, Rosenzweig HL.

Ann Rheum Dis. 2012 May;71(5):753-60. doi: 10.1136/annrheumdis-2011-200556. Epub 2012 Jan 20.

5.

Interleukin-1β regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages.

Marriott HM, Gascoyne KA, Gowda R, Geary I, Nicklin MJ, Iannelli F, Pozzi G, Mitchell TJ, Whyte MK, Sabroe I, Dockrell DH.

Infect Immun. 2012 Mar;80(3):1140-9. doi: 10.1128/IAI.05697-11. Epub 2011 Dec 12.

6.

Finally, function for "IL-1Fs".

Nicklin MJ.

Blood. 2011 Nov 24;118(22):5713-4. doi: 10.1182/blood-2011-09-379180. No abstract available.

7.

Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis.

Mohanty ST, Kottam L, Gambardella A, Nicklin MJ, Coulton L, Hughes D, Wilson AG, Croucher PI, Bellantuono I.

Arthritis Res Ther. 2010;12(4):R149. doi: 10.1186/ar3098. Epub 2010 Jul 22.

8.

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice.

Koenders MI, Devesa I, Marijnissen RJ, Abdollahi-Roodsaz S, Boots AM, Walgreen B, di Padova FE, Nicklin MJ, Joosten LA, van den Berg WB.

Arthritis Rheum. 2008 Nov;58(11):3461-70. doi: 10.1002/art.23957.

9.

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.

Abdollahi-Roodsaz S, Joosten LA, Koenders MI, Devesa I, Roelofs MF, Radstake TR, Heuvelmans-Jacobs M, Akira S, Nicklin MJ, Ribeiro-Dias F, van den Berg WB.

J Clin Invest. 2008 Jan;118(1):205-16.

10.

The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.

Magne D, Palmer G, Barton JL, Mézin F, Talabot-Ayer D, Bas S, Duffy T, Noger M, Guerne PA, Nicklin MJ, Gabay C.

Arthritis Res Ther. 2006;8(3):R80. Epub 2006 Apr 28.

11.

Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents.

Somm E, Cettour-Rose P, Asensio C, Charollais A, Klein M, Theander-Carrillo C, Juge-Aubry CE, Dayer JM, Nicklin MJ, Meda P, Rohner-Jeanrenaud F, Meier CA.

Diabetologia. 2006 Feb;49(2):387-93. Epub 2005 Dec 30.

PMID:
16385385
12.

Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.

Somm E, Henrichot E, Pernin A, Juge-Aubry CE, Muzzin P, Dayer JM, Nicklin MJ, Meier CA.

Diabetes. 2005 Dec;54(12):3503-9.

13.
14.

Psoriasis-like cutaneous inflammation in mice lacking interleukin-1 receptor antagonist.

Shepherd J, Little MC, Nicklin MJ.

J Invest Dermatol. 2004 Mar;122(3):665-9.

15.

A sequence-based map of the nine genes of the human interleukin-1 cluster.

Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K.

Genomics. 2002 May;79(5):718-25.

PMID:
11991722
16.

Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages.

Carl VS, Brown-Steinke K, Nicklin MJ, Smith MF Jr.

J Biol Chem. 2002 May 17;277(20):17448-56. Epub 2002 Mar 4.

17.

Genetic analysis of the interleukin-1 receptor antagonist and its homologue IL-1L1 in alopecia areata: strong severity association and possible gene interaction.

Tazi-Ahnini R, Cox A, McDonagh AJ, Nicklin MJ, di Giovine FS, Timms JM, Messenger AG, Dimitropoulou P, Duff GW, Cork MJ.

Eur J Immunogenet. 2002 Feb;29(1):25-30.

PMID:
11841485
18.

A new nomenclature for IL-1-family genes.

Sims JE, Nicklin MJ, Bazan JF, Barton JL, Busfield SJ, Ford JE, Kastelein RA, Kumar S, Lin H, Mulero JJ, Pan J, Pan Y, Smith DE, Young PR.

Trends Immunol. 2001 Oct;22(10):536-7. No abstract available.

PMID:
11574262
19.

Annotating genes with potential roles in the immune system: six new members of the IL-1 family.

Dunn E, Sims JE, Nicklin MJ, O'Neill LA.

Trends Immunol. 2001 Oct;22(10):533-6. No abstract available.

PMID:
11574261
20.

A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities.

Barton JL, Herbst R, Bosisio D, Higgins L, Nicklin MJ.

Eur J Immunol. 2000 Nov;30(11):3299-308.

21.

Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene.

Nicklin MJ, Hughes DE, Barton JL, Ure JM, Duff GW.

J Exp Med. 2000 Jan 17;191(2):303-12.

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Molecular cloning of the interleukin-1 gene cluster: construction of an integrated YAC/PAC contig and a partial transcriptional map in the region of chromosome 2q13.

Nothwang HG, Strahm B, Denich D, Kübler M, Schwabe J, Gingrich JC, Jauch A, Cox A, Nicklin MJ, Kurnit DM, Hildebrandt F.

Genomics. 1997 May 1;41(3):370-8.

PMID:
9169134
27.

SEZ-6: promoter selectivity, genomic structure and localized expression in the brain.

Herbst R, Nicklin MJ.

Brain Res Mol Brain Res. 1997 Mar;44(2):309-22.

PMID:
9073173
28.

Novel interleukin-1 receptor antagonist exon polymorphisms and their use in allele-specific mRNA assessment.

Clay FE, Tarlow JK, Cork MJ, Cox A, Nicklin MJ, Duff GW.

Hum Genet. 1996 Jun;97(6):723-6.

PMID:
8641687
30.
31.

Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase.

Harris KS, Reddigari SR, Nicklin MJ, Hämmerle T, Wimmer E.

J Virol. 1992 Dec;66(12):7481-9.

32.
33.

Cleavage of synthetic peptides by purified poliovirus 3C proteinase.

Pallai PV, Burkhardt F, Skoog M, Schreiner K, Bax P, Cohen KA, Hansen G, Palladino DE, Harris KS, Nicklin MJ, et al.

J Biol Chem. 1989 Jun 15;264(17):9738-41.

35.

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation.

Jang SK, Kräusslich HG, Nicklin MJ, Duke GM, Palmenberg AC, Wimmer E.

J Virol. 1988 Aug;62(8):2636-43.

36.

Polyprotein processing in picornavirus replication.

Kräusslich HG, Nicklin MJ, Lee CK, Wimmer E.

Biochimie. 1988 Jan;70(1):119-30.

PMID:
2840974
37.

Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220.

Kräusslich HG, Nicklin MJ, Toyoda H, Etchison D, Wimmer E.

J Virol. 1987 Sep;61(9):2711-8.

38.

Poliovirus polypeptide precursors: expression in vitro and processing by exogenous 3C and 2A proteinases.

Nicklin MJ, Kräusslich HG, Toyoda H, Dunn JJ, Wimmer E.

Proc Natl Acad Sci U S A. 1987 Jun;84(12):4002-6.

39.

Implications of the picornavirus capsid structure for polyprotein processing.

Arnold E, Luo M, Vriend G, Rossmann MG, Palmenberg AC, Parks GD, Nicklin MJ, Wimmer E.

Proc Natl Acad Sci U S A. 1987 Jan;84(1):21-5.

40.

Molecular events leading to picornavirus genome replication.

Wimmer E, Kuhn RJ, Pincus S, Yang CF, Toyoda H, Nicklin MJ, Takeda N.

J Cell Sci Suppl. 1987;7:251-76. Review. No abstract available.

PMID:
2846594
41.

A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein.

Toyoda H, Nicklin MJ, Murray MG, Anderson CW, Dunn JJ, Studier FW, Wimmer E.

Cell. 1986 Jun 6;45(5):761-70.

PMID:
3011278
42.

The proteolytic activities of chymopapain, papain, and papaya proteinase III.

Zucker S, Buttle DJ, Nicklin MJ, Barrett AJ.

Biochim Biophys Acta. 1985 Apr 5;828(2):196-204.

PMID:
3919769
43.
45.

Cystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum.

Anastasi A, Brown MA, Kembhavi AA, Nicklin MJ, Sayers CA, Sunter DC, Barrett AJ.

Biochem J. 1983 Apr 1;211(1):129-38.

46.

Rapid irregular movements of eyes and limbs.

Nicklin MJ.

Br Med J. 1972 Mar 25;1(5803):807. No abstract available.

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