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Items: 29

1.

Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models.

Xiong H, Mittman S, Rodriguez R, Pacheco-Sanchez P, Moskalenko M, Yang Y, Elstrott J, Ritter AT, Müller S, Nickles D, Arenzana TL, Capietto AH, Delamarre L, Modrusan Z, Rutz S, Mellman I, Cubas R.

Cancer Immunol Res. 2019 Jun;7(6):963-976. doi: 10.1158/2326-6066.CIR-18-0750. Epub 2019 May 7.

PMID:
31064777
2.

Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.

Long JE, Wongchenko MJ, Nickles D, Chung WJ, Wang BE, Riegler J, Li J, Li Q, Sandoval W, Eastham-Anderson J, Modrusan Z, Junttila T, Carano RAD, Foreman O, Yan Y, Junttila MR.

Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0310-0. [Epub ahead of print]

PMID:
30824837
3.

Anti-PD-L1 Treatment Results in Functional Remodeling of the Macrophage Compartment.

Xiong H, Mittman S, Rodriguez R, Moskalenko M, Pacheco-Sanchez P, Yang Y, Nickles D, Cubas R.

Cancer Res. 2019 Apr 1;79(7):1493-1506. doi: 10.1158/0008-5472.CAN-18-3208. Epub 2019 Jan 24.

PMID:
30679180
4.

Publisher Correction: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott DF, Huseni MA, Atkins MB, Motzer RJ, Rini BI, Escudier B, Fong L, Joseph RW, Pal SK, Reeves JA, Sznol M, Hainsworth J, Rathmell WK, Stadler WM, Hutson T, Gore ME, Ravaud A, Bracarda S, Suárez C, Danielli R, Gruenwald V, Choueiri TK, Nickles D, Jhunjhunwala S, Piault-Louis E, Thobhani A, Qiu J, Chen DS, Hegde PS, Schiff C, Fine GD, Powles T.

Nat Med. 2018 Dec;24(12):1941. doi: 10.1038/s41591-018-0235-z.

PMID:
30291359
5.

Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott DF, Huseni MA, Atkins MB, Motzer RJ, Rini BI, Escudier B, Fong L, Joseph RW, Pal SK, Reeves JA, Sznol M, Hainsworth J, Rathmell WK, Stadler WM, Hutson T, Gore ME, Ravaud A, Bracarda S, Suárez C, Danielli R, Gruenwald V, Choueiri TK, Nickles D, Jhunjhunwala S, Piault-Louis E, Thobhani A, Qiu J, Chen DS, Hegde PS, Schiff C, Fine GD, Powles T.

Nat Med. 2018 Jun;24(6):749-757. doi: 10.1038/s41591-018-0053-3. Epub 2018 Jun 4. Erratum in: Nat Med. 2018 Dec;24(12):1941.

PMID:
29867230
6.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE III, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Şenbabaoğlu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T.

Nature. 2018 Feb 22;554(7693):544-548. doi: 10.1038/nature25501. Epub 2018 Feb 14.

7.

Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis.

Fewings N, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR.

Data Brief. 2017 Feb 21;11:364-370. doi: 10.1016/j.dib.2017.02.040. eCollection 2017 Apr.

8.

The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis.

Fewings NL, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR.

J Autoimmun. 2017 Mar;78:57-69. doi: 10.1016/j.jaut.2016.12.006. Epub 2017 Jan 4.

PMID:
28063629
9.

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.

Rosenberg JE, Hoffman-Censits J, Powles T, van der Heijden MS, Balar AV, Necchi A, Dawson N, O'Donnell PH, Balmanoukian A, Loriot Y, Srinivas S, Retz MM, Grivas P, Joseph RW, Galsky MD, Fleming MT, Petrylak DP, Perez-Gracia JL, Burris HA, Castellano D, Canil C, Bellmunt J, Bajorin D, Nickles D, Bourgon R, Frampton GM, Cui N, Mariathasan S, Abidoye O, Fine GD, Dreicer R.

Lancet. 2016 May 7;387(10031):1909-20. doi: 10.1016/S0140-6736(16)00561-4. Epub 2016 Mar 4.

10.

Whole genome sequences of 2 octogenarians with sustained cognitive abilities.

Nickles D, Madireddy L, Patel N, Isobe N, Miller BL, Baranzini SE, Kramer JH, Oksenberg JR.

Neurobiol Aging. 2015 Mar;36(3):1435-8. doi: 10.1016/j.neurobiolaging.2014.11.003. Epub 2014 Dec 16.

11.

Rituximab efficiently depletes increased CD20-expressing T cells in multiple sclerosis patients.

Palanichamy A, Jahn S, Nickles D, Derstine M, Abounasr A, Hauser SL, Baranzini SE, Leppert D, von Büdingen HC.

J Immunol. 2014 Jul 15;193(2):580-586. doi: 10.4049/jimmunol.1400118. Epub 2014 Jun 13.

12.

The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease.

Parnell GP, Gatt PN, Krupa M, Nickles D, McKay FC, Schibeci SD, Batten M, Baranzini S, Henderson A, Barnett M, Slee M, Vucic S, Stewart GJ, Booth DR.

Clin Immunol. 2014 Mar;151(1):16-24. doi: 10.1016/j.clim.2014.01.003. Epub 2014 Jan 15.

13.

Sequencing of the IL6 gene in a case-control study of cerebral palsy in children.

Khankhanian P, Baranzini SE, Johnson BA, Madireddy L, Nickles D, Croen LA, Wu YW.

BMC Med Genet. 2013 Dec 7;14:126. doi: 10.1186/1471-2350-14-126.

14.

Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls.

Nickles D, Chen HP, Li MM, Khankhanian P, Madireddy L, Caillier SJ, Santaniello A, Cree BA, Pelletier D, Hauser SL, Oksenberg JR, Baranzini SE.

Hum Mol Genet. 2013 Oct 15;22(20):4194-205. doi: 10.1093/hmg/ddt267. Epub 2013 Jun 6.

15.

A PP4 holoenzyme balances physiological and oncogenic nuclear factor-kappa B signaling in T lymphocytes.

Brechmann M, Mock T, Nickles D, Kiessling M, Weit N, Breuer R, Müller W, Wabnitz G, Frey F, Nicolay JP, Booken N, Samstag Y, Klemke CD, Herling M, Boutros M, Krammer PH, Arnold R.

Immunity. 2012 Oct 19;37(4):697-708. doi: 10.1016/j.immuni.2012.07.014.

16.

In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing.

Nickles D, Madireddy L, Yang S, Khankhanian P, Lincoln S, Hauser SL, Oksenberg JR, Baranzini SE.

BMC Genomics. 2012 Sep 14;13:477. doi: 10.1186/1471-2164-13-477.

17.

A genome-wide RNA interference screen identifies caspase 4 as a factor required for tumor necrosis factor alpha signaling.

Nickles D, Falschlehner C, Metzig M, Boutros M.

Mol Cell Biol. 2012 Sep;32(17):3372-81. doi: 10.1128/MCB.06739-11. Epub 2012 Jun 25.

18.

Genetics of multiple sclerosis: swimming in an ocean of data.

Baranzini SE, Nickles D.

Curr Opin Neurol. 2012 Jun;25(3):239-45. doi: 10.1097/WCO.0b013e3283533a93. Review.

PMID:
22516854
19.

An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling.

Metzig M, Nickles D, Falschlehner C, Lehmann-Koch J, Straub BK, Roth W, Boutros M.

Int J Cancer. 2011 Aug 1;129(3):607-18. doi: 10.1002/ijc.26124.

20.

Large-scale RNAi screens to dissect TNF and NF-κB signaling pathways.

Metzig M, Nickles D, Boutros M.

Adv Exp Med Biol. 2011;691:131-9. doi: 10.1007/978-1-4419-6612-4_14. No abstract available.

PMID:
21153317
21.

End-stage dying glioma cells are engulfed by mouse microglia with a strain-dependent efficacy.

Nickles D, Abschuetz A, Zimmer H, Kees T, Geibig R, Spiess E, Régnier-Vigouroux A.

J Neuroimmunol. 2008 Jun 15;197(1):10-20. doi: 10.1016/j.jneuroim.2008.03.022. Epub 2008 May 20.

PMID:
18495256
22.

Distributed interactive virtual environments for collaborative medical education and training: design and characterization.

Mowafil MY, Summers KL, Holten J, Greenfield JA, Sherstyuk A, Nickles D, Aalseth E, Takamiya W, Saiki S, Alverson D, Caudell TP.

Stud Health Technol Inform. 2004;98:259-61.

PMID:
15544284
23.

Distributed interactive virtual environments for collaborative experiential learning and training independent of distance over Internet2.

Alverson DC, Saiki SM Jr, Jacobs J, Saland L, Keep MF, Norenberg J, Baker R, Nakatsu C, Kalishman S, Lindberg M, Wax D, Mowafi M, Summers KL, Holten JR, Greenfield JA, Aalseth E, Nickles D, Sherstyuk A, Haines K, Caudell TP.

Stud Health Technol Inform. 2004;98:7-12.

PMID:
15544229
24.

The voices of reform. The final stretch. Interview by Renee Blankenau.

Mitchell G, McDermott J, Chafee J, Rockefeller J, Breaux J, Stark P, Nickles D, Waxman H, Grandy F, Kennedy E, et al.

Hosp Health Netw. 1994 Jan 20;68(2):22-5.

PMID:
8275125
25.
26.

Dapsone hepatitis.

Lawrence WA, Olsen HW, Nickles DJ.

Arch Intern Med. 1987 Jan;147(1):175. No abstract available.

PMID:
3800520
27.

[Respiration- and ECG-gated data collection in a data processing system controlled by a microcomputer].

Nickles D, Rösner T, Mohnike W, Millebrandt F.

Radiobiol Radiother (Berl). 1987;28(2):217-20. German. No abstract available.

PMID:
3659309
28.

[Results of animal experiment tests of technetium-99m-DMPE in minipigs].

Schmidt J, Mohnike W, Muschik P, Nickles D, Seifert S, Syhre R, Bach H, Hartrodt W, Rohde E, Münze R, et al.

Radiobiol Radiother (Berl). 1986;27(1):97-100. German. No abstract available.

PMID:
3704136
29.

Federal policy on health insurance benefits for abortion.

Denton J, Nickles D, Jepsen RW, Helms J, Zorinsky E.

Congr Rec (Dly Ed). 1981 Dec 14;127(186):S15190-2. No abstract available.

PMID:
11655485

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