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Items: 17


Structural and Functional Variation in Outer Membrane Polysaccharide Export (OPX) Proteins from the Two Major Capsule Assembly Pathways Present in Escherichia coli.

Sande C, Bouwman C, Kell E, Nickerson NN, Kapadia SB, Whitfield C.

J Bacteriol. 2019 Jun 21;201(14). pii: e00213-19. doi: 10.1128/JB.00213-19. Print 2019 Jul 15.


Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA.

Alexander MK, Miu A, Oh A, Reichelt M, Ho H, Chalouni C, Labadie S, Wang L, Liang J, Nickerson NN, Hu H, Yu L, Du M, Yan D, Park S, Kim J, Xu M, Sellers BD, Purkey HE, Skelton NJ, Koehler MFT, Payandeh J, Verma V, Xu Y, Koth CM, Nishiyama M.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01142-18. doi: 10.1128/AAC.01142-18. Print 2018 Nov.


Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal.

Storek KM, Auerbach MR, Shi H, Garcia NK, Sun D, Nickerson NN, Vij R, Lin Z, Chiang N, Schneider K, Wecksler AT, Skippington E, Nakamura G, Seshasayee D, Koerber JT, Payandeh J, Smith PA, Rutherford ST.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3692-3697. doi: 10.1073/pnas.1800043115. Epub 2018 Mar 19.


A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria.

Nickerson NN, Jao CC, Xu Y, Quinn J, Skippington E, Alexander MK, Miu A, Skelton N, Hankins JV, Lopez MS, Koth CM, Rutherford S, Nishiyama M.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02151-17. doi: 10.1128/AAC.02151-17. Print 2018 Apr.


Peptidoglycan Association of Murein Lipoprotein Is Required for KpsD-Dependent Group 2 Capsular Polysaccharide Expression and Serum Resistance in a Uropathogenic Escherichia coli Isolate.

Diao J, Bouwman C, Yan D, Kang J, Katakam AK, Liu P, Pantua H, Abbas AR, Nickerson NN, Austin C, Reichelt M, Sandoval W, Xu M, Whitfield C, Kapadia SB.

MBio. 2017 May 23;8(3). pii: e00603-17. doi: 10.1128/mBio.00603-17.


Genetic, Biochemical, and Structural Analyses of Bacterial Surface Polysaccharides.

Cooper CA, Mainprize IL, Nickerson NN.

Adv Exp Med Biol. 2015;883:295-315. doi: 10.1007/978-3-319-23603-2_16. Review.


Lipids assist the membrane insertion of a BAM-independent outer membrane protein.

Huysmans GH, Guilvout I, Chami M, Nickerson NN, Pugsley AP.

Sci Rep. 2015 Oct 14;5:15068. doi: 10.1038/srep15068.


Trapped translocation intermediates establish the route for export of capsular polysaccharides across Escherichia coli outer membranes.

Nickerson NN, Mainprize IL, Hampton L, Jones ML, Naismith JH, Whitfield C.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8203-8. doi: 10.1073/pnas.1400341111. Epub 2014 May 19.


Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30.

McGavin MJ, Arsic B, Nickerson NN.

Front Cell Infect Microbiol. 2012 Apr 9;2:48. doi: 10.3389/fcimb.2012.00048. eCollection 2012.


A Single Amino Acid Substitution Changes the Self-Assembly Status of a Type IV Piliation Secretin.

Nickerson NN, Abby SS, Rocha EP, Chami M, Pugsley AP.

J Bacteriol. 2012 Sep;194(18):4951-8. doi: 10.1128/JB.00798-12. Epub 2012 Jul 6.


Outer membrane targeting of Pseudomonas aeruginosa proteins shows variable dependence on the components of Bam and Lol machineries.

Hoang HH, Nickerson NN, Lee VT, Kazimirova A, Chami M, Pugsley AP, Lory S.

MBio. 2011 Dec 6;2(6). pii: e00246-11. doi: 10.1128/mBio.00246-11. Print 2011.


Pilotin-secretin recognition in the type II secretion system of Klebsiella oxytoca.

Tosi T, Nickerson NN, Mollica L, Jensen MR, Blackledge M, Baron B, England P, Pugsley AP, Dessen A.

Mol Microbiol. 2011 Dec;82(6):1422-32. doi: 10.1111/j.1365-2958.2011.07896.x. Epub 2011 Nov 21.


Outer membrane targeting of secretin PulD protein relies on disordered domain recognition by a dedicated chaperone.

Nickerson NN, Tosi T, Dessen A, Baron B, Raynal B, England P, Pugsley AP.

J Biol Chem. 2011 Nov 11;286(45):38833-43. doi: 10.1074/jbc.M111.279851. Epub 2011 Aug 30.


Sorting of an integral outer membrane protein via the lipoprotein-specific Lol pathway and a dedicated lipoprotein pilotin.

Collin S, Guilvout I, Nickerson NN, Pugsley AP.

Mol Microbiol. 2011 May;80(3):655-65. doi: 10.1111/j.1365-2958.2011.07596.x. Epub 2011 Mar 7.


Multimerization-defective variants of dodecameric secretin PulD.

Guilvout I, Nickerson NN, Chami M, Pugsley AP.

Res Microbiol. 2011 Feb-Mar;162(2):180-90. doi: 10.1016/j.resmic.2011.01.006. Epub 2011 Jan 20.


Rapid autocatalytic activation of the M4 metalloprotease aureolysin is controlled by a conserved N-terminal fungalysin-thermolysin-propeptide domain.

Nickerson NN, Joag V, McGavin MJ.

Mol Microbiol. 2008 Sep;69(6):1530-43. doi: 10.1111/j.1365-2958.2008.06384.x. Epub 2008 Jul 30.

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