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Items: 44

1.

Regulation of P2X7 receptor expression and function in the brain.

Jimenez-Mateos EM, Smith J, Nicke A, Engel T.

Brain Res Bull. 2018 Dec 26. pii: S0361-9230(18)30734-2. doi: 10.1016/j.brainresbull.2018.12.008. [Epub ahead of print] Review.

PMID:
30593878
2.

Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.

Kaczmarek-Hajek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, Bruzzone S, Engel T, Jooss T, Krautloher A, Schuster S, Magnus T, Stadelmann C, Sirko S, Koch-Nolte F, Eulenburg V, Nicke A.

Elife. 2018 Aug 3;7. pii: e36217. doi: 10.7554/eLife.36217.

3.

Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus.

Giribaldi J, Wilson D, Nicke A, El Hamdaoui Y, Laconde G, Faucherre A, Moha Ou Maati H, Daly NL, Enjalbal C, Dutertre S.

Toxins (Basel). 2018 Jun 1;10(6). pii: E222. doi: 10.3390/toxins10060222.

4.

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.

Leffler AE, Kuryatov A, Zebroski HA, Powell SR, Filipenko P, Hussein AK, Gorson J, Heizmann A, Lyskov S, Tsien RW, Poget SF, Nicke A, Lindstrom J, Rudy B, Bonneau R, Holford M.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E8100-E8109. doi: 10.1073/pnas.1703952114. Epub 2017 Sep 5.

5.

Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms.

Dutertre S, Nicke A, Tsetlin VI.

Neuropharmacology. 2017 Dec;127:196-223. doi: 10.1016/j.neuropharm.2017.06.011. Epub 2017 Jun 13. Review.

PMID:
28623170
6.

Heteromeric assembly of P2X subunits.

Saul A, Hausmann R, Kless A, Nicke A.

Front Cell Neurosci. 2013 Dec 18;7:250. doi: 10.3389/fncel.2013.00250. Review.

7.

The phenothiazine-class antipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor.

Hempel C, Nörenberg W, Sobottka H, Urban N, Nicke A, Fischer W, Schaefer M.

Neuropharmacology. 2013 Dec;75:365-79. doi: 10.1016/j.neuropharm.2013.07.027. Epub 2013 Aug 14.

PMID:
23954492
8.

Validation of Alexa-647-ATP as a powerful tool to study P2X receptor ligand binding and desensitization.

Bhargava Y, Nicke A, Rettinger J.

Biochem Biophys Res Commun. 2013 Aug 23;438(2):295-300. doi: 10.1016/j.bbrc.2013.07.058. Epub 2013 Jul 26.

PMID:
23896604
9.

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors.

Kendel Y, Melaun C, Kurz A, Nicke A, Peigneur S, Tytgat J, Wunder C, Mebs D, Kauferstein S.

Toxins (Basel). 2013 May 21;5(5):1043-50. doi: 10.3390/toxins5051043.

10.

Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

Schwarz N, Drouot L, Nicke A, Fliegert R, Boyer O, Guse AH, Haag F, Adriouch S, Koch-Nolte F.

PLoS One. 2012;7(7):e41269. doi: 10.1371/journal.pone.0041269. Epub 2012 Jul 27.

11.

Efficient binding of 4/7 α-conotoxins to nicotinic α4β2 receptors is prevented by Arg185 and Pro195 in the α4 subunit.

Beissner M, Dutertre S, Schemm R, Danker T, Sporning A, Grubmüller H, Nicke A.

Mol Pharmacol. 2012 Oct;82(4):711-8. Epub 2012 Jul 16.

PMID:
22802270
12.

Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor.

Lörinczi É, Bhargava Y, Marino SF, Taly A, Kaczmarek-Hájek K, Barrantes-Freer A, Dutertre S, Grutter T, Rettinger J, Nicke A.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11396-401. doi: 10.1073/pnas.1118759109. Epub 2012 Jun 27.

13.

Molecular and functional properties of P2X receptors--recent progress and persisting challenges.

Kaczmarek-Hájek K, Lörinczi E, Hausmann R, Nicke A.

Purinergic Signal. 2012 Sep;8(3):375-417. doi: 10.1007/s11302-012-9314-7. Epub 2012 May 1. Review.

14.

Venomic study on cone snails (Conus spp.) from South Africa.

Kauferstein S, Porth C, Kendel Y, Wunder C, Nicke A, Kordis D, Favreau P, Koua D, Stöcklin R, Mebs D.

Toxicon. 2011 Jan;57(1):28-34. doi: 10.1016/j.toxicon.2010.09.009. Epub 2010 Oct 8.

PMID:
20933537
15.

A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice.

Nicke A, Kuan YH, Masin M, Rettinger J, Marquez-Klaka B, Bender O, Górecki DC, Murrell-Lagnado RD, Soto F.

J Biol Chem. 2009 Sep 18;284(38):25813-22. doi: 10.1074/jbc.M109.033134. Epub 2009 Jun 22.

16.

New conopeptides of the D-superfamily selectively inhibiting neuronal nicotinic acetylcholine receptors.

Kauferstein S, Kendel Y, Nicke A, Coronas FI, Possani LD, Favreau P, Krizaj I, Wunder C, Kauert G, Mebs D.

Toxicon. 2009 Sep 1;54(3):295-301. doi: 10.1016/j.toxicon.2009.04.016. Epub 2009 Apr 23.

PMID:
19393680
17.

Novel alpha D-conopeptides and their precursors identified by cDNA cloning define the D-conotoxin superfamily.

Loughnan ML, Nicke A, Lawrence N, Lewis RJ.

Biochemistry. 2009 May 5;48(17):3717-29. doi: 10.1021/bi9000326.

PMID:
19275168
18.

Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues.

Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL.

J Biol Chem. 2009 Feb 20;284(8):4944-51. doi: 10.1074/jbc.M804950200. Epub 2008 Dec 19.

19.

Homotrimeric complexes are the dominant assembly state of native P2X7 subunits.

Nicke A.

Biochem Biophys Res Commun. 2008 Dec 19;377(3):803-8. doi: 10.1016/j.bbrc.2008.10.042. Epub 2008 Oct 18.

PMID:
18938136
20.

Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors.

Marquez-Klaka B, Rettinger J, Nicke A.

Eur Biophys J. 2009 Mar;38(3):329-38. doi: 10.1007/s00249-008-0325-9. Epub 2008 Apr 22.

PMID:
18427801
21.

Glycine transporter dimers: evidence for occurrence in the plasma membrane.

Bartholomäus I, Milan-Lobo L, Nicke A, Dutertre S, Hastrup H, Jha A, Gether U, Sitte HH, Betz H, Eulenburg V.

J Biol Chem. 2008 Apr 18;283(16):10978-91. doi: 10.1074/jbc.M800622200. Epub 2008 Feb 5.

22.

Quaternary structure and apical membrane sorting of the mammalian NaSi-1 sulfate transporter in renal cell lines.

Regeer RR, Nicke A, Markovich D.

Int J Biochem Cell Biol. 2007;39(12):2240-51. Epub 2007 Jul 5.

PMID:
17681482
23.

AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity.

Dutertre S, Ulens C, Büttner R, Fish A, van Elk R, Kendel Y, Hopping G, Alewood PF, Schroeder C, Nicke A, Smit AB, Sixma TK, Lewis RJ.

EMBO J. 2007 Aug 22;26(16):3858-67. Epub 2007 Jul 26.

24.

[Innovative prenatal diagnosis].

Nicke A.

Pharm Unserer Zeit. 2007;36(3):170-2. German. No abstract available.

PMID:
17555049
25.
26.

Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function.

Madry C, Mesic I, Bartholomäus I, Nicke A, Betz H, Laube B.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):102-8. Epub 2006 Dec 28.

PMID:
17214961
27.

Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum.

Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ.

J Biol Chem. 2006 Aug 25;281(34):24745-55. Epub 2006 Jun 21.

28.

Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylcholine receptor.

Dutertre S, Nicke A, Lewis RJ.

J Biol Chem. 2005 Aug 26;280(34):30460-8. Epub 2005 Jun 1.

29.

The beta subunit determines the ligand binding properties of synaptic glycine receptors.

Grudzinska J, Schemm R, Haeger S, Nicke A, Schmalzing G, Betz H, Laube B.

Neuron. 2005 Mar 3;45(5):727-39.

30.

Biochemical and functional evidence for heteromeric assembly of P2X1 and P2X4 subunits.

Nicke A, Kerschensteiner D, Soto F.

J Neurochem. 2005 Feb;92(4):925-33.

31.

Assembly of nicotinic alpha7 subunits in Xenopus oocytes is partially blocked at the tetramer level.

Nicke A, Thurau H, Sadtler S, Rettinger J, Schmalzing G.

FEBS Lett. 2004 Sep 24;575(1-3):52-8.

32.

Determination of alpha-conotoxin binding modes on neuronal nicotinic acetylcholine receptors.

Dutertre S, Nicke A, Tyndall JD, Lewis RJ.

J Mol Recognit. 2004 Jul-Aug;17(4):339-47.

PMID:
15227641
33.
34.
35.

Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone.

Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ.

J Med Chem. 2004 Feb 26;47(5):1234-41.

PMID:
14971903
36.

Alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors.

Nicke A, Samochocki M, Loughnan ML, Bansal PS, Maelicke A, Lewis RJ.

FEBS Lett. 2003 Nov 6;554(1-2):219-23. Erratum in: FEBS Lett. 2004 Jan 16;557(1-3):294.

37.

A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit.

Sadtler S, Laube B, Lashub A, Nicke A, Betz H, Schmalzing G.

J Biol Chem. 2003 May 9;278(19):16782-90. Epub 2003 Feb 28.

38.

Monomeric and dimeric byproducts are the principal functional elements of higher order P2X1 concatamers.

Nicke A, Rettinger J, Schmalzing G.

Mol Pharmacol. 2003 Jan;63(1):243-52.

PMID:
12488557
39.

Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence.

Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ.

J Biol Chem. 2003 Jan 31;278(5):3137-44. Epub 2002 Nov 4.

40.

Surface-localized glycine transporters 1 and 2 function as monomeric proteins in Xenopus oocytes.

Horiuchi M, Nicke A, Gomeza J, Aschrafi A, Schmalzing G, Betz H.

Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1448-53. Epub 2001 Feb 6.

41.

Evolving view of quaternary structures of ligand-gated ion channels.

Nicke A, Rettinger J, Büttner C, Eichele A, Lambrecht G, Schmalzing G.

Prog Brain Res. 1999;120:61-80. Review. No abstract available.

PMID:
10550988
42.

Molecular determinants of glycine receptor subunit assembly.

Griffon N, Büttner C, Nicke A, Kuhse J, Schmalzing G, Betz H.

EMBO J. 1999 Sep 1;18(17):4711-21.

43.

Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits.

Nicke A, Rettinger J, Mutschler E, Schmalzing G.

J Recept Signal Transduct Res. 1999 Jan-Jul;19(1-4):493-507.

PMID:
10071780
44.

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels.

Nicke A, Bäumert HG, Rettinger J, Eichele A, Lambrecht G, Mutschler E, Schmalzing G.

EMBO J. 1998 Jun 1;17(11):3016-28.

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