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Items: 4

1.

HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.

Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG Jr.

Sci Signal. 2019 Oct 1;12(601). pii: eaay0482. doi: 10.1126/scisignal.aay0482.

PMID:
31575731
2.

Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.

Schade AE, Oser MG, Nicholson HE, DeCaprio JA.

Oncogene. 2019 Jun;38(25):4962-4976. doi: 10.1038/s41388-019-0767-9. Epub 2019 Mar 4.

3.

Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives.

Nicholson HE, Alsharif WF, Comeau AB, Mesangeau C, Intagliata S, Mottinelli M, McCurdy CR, Bowen WD.

J Pharmacol Exp Ther. 2019 Feb;368(2):272-281. doi: 10.1124/jpet.118.253484. Epub 2018 Dec 7.

PMID:
30530624
4.

Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells.

Housden BE, Nicholson HE, Perrimon N.

Bio Protoc. 2017 Feb 5;7(3). pii: e2119. doi: 10.21769/BioProtoc.2119.

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