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Items: 1 to 50 of 77

1.

Permeant-specific gating of connexin 30 hemichannels.

Nielsen BS, Alstrom JS, Nicholson BJ, Nielsen MS, MacAulay N.

J Biol Chem. 2017 Dec 8;292(49):19999-20009. doi: 10.1074/jbc.M117.805986. Epub 2017 Oct 5.

PMID:
28982982
2.

Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.

Polusani SR, Kalmykov EA, Chandrasekhar A, Zucker SN, Nicholson BJ.

J Cell Sci. 2016 Dec 1;129(23):4399-4410. Epub 2016 Oct 24.

3.

The contribution of Chlamydia-specific CD8⁺ T cells to upper genital tract pathology.

Vlcek KR, Li W, Manam S, Zanotti B, Nicholson BJ, Ramsey KH, Murthy AK.

Immunol Cell Biol. 2016 Feb;94(2):208-12. doi: 10.1038/icb.2015.74. Epub 2015 Sep 1.

4.

Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice.

Morton SK, Chaston DJ, Howitt L, Heisler J, Nicholson BJ, Fairweather S, Bröer S, Ashton AW, Matthaei KI, Hill CE.

Hypertension. 2015 Mar;65(3):662-9. doi: 10.1161/HYPERTENSIONAHA.114.04578. Epub 2014 Dec 29.

5.

Intercellular redistribution of cAMP underlies selective suppression of cancer cell growth by connexin26.

Chandrasekhar A, Kalmykov EA, Polusani SR, Mathis SA, Zucker SN, Nicholson BJ.

PLoS One. 2013 Dec 3;8(12):e82335. doi: 10.1371/journal.pone.0082335. eCollection 2013.

6.

Cataract-causing mutation of human connexin 46 impairs gap junction, but increases hemichannel function and cell death.

Ren Q, Riquelme MA, Xu J, Yan X, Nicholson BJ, Gu S, Jiang JX.

PLoS One. 2013 Sep 3;8(9):e74732. doi: 10.1371/journal.pone.0074732. eCollection 2013.

7.

OT-1 mice display minimal upper genital tract pathology following primary intravaginal Chlamydia muridarum infection.

Manam S, Nicholson BJ, Murthy AK.

Pathog Dis. 2013 Apr;67(3):221-4. doi: 10.1111/2049-632X.12032. Epub 2013 Mar 11.

8.

Polymorphism in endothelial connexin40 enhances sensitivity to intraluminal pressure and increases arterial stiffness.

Chaston DJ, Baillie BK, Grayson TH, Courjaret RJ, Heisler JM, Lau KA, Machaca K, Nicholson BJ, Ashton A, Matthaei KI, Hill CE.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):962-70. doi: 10.1161/ATVBAHA.112.300957. Epub 2013 Mar 7.

9.

Identification of a disulfide bridge important for transport function of SNAT4 neutral amino acid transporter.

Padmanabhan Iyer R, Gu S, Nicholson BJ, Jiang JX.

PLoS One. 2013;8(2):e56792. doi: 10.1371/journal.pone.0056792. Epub 2013 Feb 22.

10.

Residue cysteine 232 is important for substrate transport of neutral amino acid transporter, SNAT4.

Padmanabhan R, Gu S, Nicholson BJ, Jiang JX.

Int J Biochem Mol Biol. 2012;3(4):374-83. Epub 2012 Dec 24.

11.

Coregulation of multiple signaling mechanisms in pp60v-Src-induced closure of Cx43 gap junction channels.

Mitra SS, Xu J, Nicholson BJ.

J Membr Biol. 2012 Aug;245(8):495-506. Epub 2012 Sep 11.

12.

The role of connexins in ear and skin physiology - functional insights from disease-associated mutations.

Xu J, Nicholson BJ.

Biochim Biophys Acta. 2013 Jan;1828(1):167-78. doi: 10.1016/j.bbamem.2012.06.024. Epub 2012 Jul 13. Review.

13.

Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50.

Liu J, Xu J, Gu S, Nicholson BJ, Jiang JX.

J Cell Sci. 2011 Jan 15;124(Pt 2):198-206. doi: 10.1242/jcs.072652. Epub 2010 Dec 20.

14.

Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.

Oshima A, Tani K, Toloue MM, Hiroaki Y, Smock A, Inukai S, Cone A, Nicholson BJ, Sosinsky GE, Fujiyoshi Y.

J Mol Biol. 2011 Jan 21;405(3):724-35. doi: 10.1016/j.jmb.2010.10.032. Epub 2010 Nov 20.

15.

Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue.

Thibodeau IL, Xu J, Li Q, Liu G, Lam K, Veinot JP, Birnie DH, Jones DL, Krahn AD, Lemery R, Nicholson BJ, Gollob MH.

Circulation. 2010 Jul 20;122(3):236-44. doi: 10.1161/CIRCULATIONAHA.110.961227. Epub 2010 Jul 6.

16.

Analysis of four connexin26 mutant gap junctions and hemichannels reveals variations in hexamer stability.

Ambrosi C, Boassa D, Pranskevich J, Smock A, Oshima A, Xu J, Nicholson BJ, Sosinsky GE.

Biophys J. 2010 May 19;98(9):1809-19. doi: 10.1016/j.bpj.2010.01.019.

17.

Peripheral modulation of worker bee responses to queen mandibular pheromone.

Vergoz V, McQuillan HJ, Geddes LH, Pullar K, Nicholson BJ, Paulin MG, Mercer AR.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20930-5. doi: 10.1073/pnas.0907563106. Epub 2009 Nov 23.

18.

Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous system.

Starich TA, Xu J, Skerrett IM, Nicholson BJ, Shaw JE.

Neural Dev. 2009 May 11;4:16. doi: 10.1186/1749-8104-4-16.

19.

Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner.

Banks EA, Toloue MM, Shi Q, Zhou ZJ, Liu J, Nicholson BJ, Jiang JX.

J Cell Sci. 2009 Feb 1;122(Pt 3):378-88. doi: 10.1242/jcs.034124. Epub 2009 Jan 6.

20.

Site-directed mutagenesis reveals putative regions of protein interaction within the transmembrane domains of connexins.

Toloue MM, Woolwine Y, Karcz JA, Kasperek EM, Nicholson BJ, Skerrett IM.

Cell Commun Adhes. 2008 May;15(1):95-105. doi: 10.1080/15419060802013463.

21.

Mutation of a conserved threonine in the third transmembrane helix of alpha- and beta-connexins creates a dominant-negative closed gap junction channel.

Beahm DL, Oshima A, Gaietta GM, Hand GM, Smock AE, Zucker SN, Toloue MM, Chandrasekhar A, Nicholson BJ, Sosinsky GE.

J Biol Chem. 2006 Mar 24;281(12):7994-8009. Epub 2005 Dec 28.

22.

Connexin expression and cell coupling fail to reverse the v-src transformed growth characteristics of a Cx43-/- cell line.

Chandrasekhar A, Merritt M, Huh SJ, Nicholson BJ, Zucker SN.

Cell Commun Adhes. 2004 Mar-Aug;11(2-4):103-19.

PMID:
16194879
23.

Structural organization of gap junction channels.

Sosinsky GE, Nicholson BJ.

Biochim Biophys Acta. 2005 Jun 10;1711(2):99-125. Epub 2005 Apr 19. Review.

24.
26.

Aberrant gating, but a normal expression pattern, underlies the recessive phenotype of the deafness mutant Connexin26M34T.

Skerrett IM, Di WL, Kasperek EM, Kelsell DP, Nicholson BJ.

FASEB J. 2004 May;18(7):860-2. Epub 2004 Mar 19.

PMID:
15033936
27.

Effective asymmetry in gap junctional intercellular communication between populations of human normal lung fibroblasts and lung carcinoma cells.

Zhang ZQ, Hu Y, Wang BJ, Lin ZX, Naus CC, Nicholson BJ.

Carcinogenesis. 2004 Apr;25(4):473-82. Epub 2003 Dec 4.

PMID:
14656943
28.

Gap junctions - from cell to molecule.

Nicholson BJ.

J Cell Sci. 2003 Nov 15;116(Pt 22):4479-81. Review. No abstract available.

29.

Mutagenic approaches to modifying gap junction phenotype.

Zucker SN, Nicholson BJ.

Curr Drug Targets. 2002 Dec;3(6):441-53. Review.

PMID:
12448696
30.

Identification of amino acid residues lining the pore of a gap junction channel.

Skerrett IM, Aronowitz J, Shin JH, Cymes G, Kasperek E, Cao FL, Nicholson BJ.

J Cell Biol. 2002 Oct 28;159(2):349-60. Epub 2002 Oct 28.

31.

Size selectivity between gap junction channels composed of different connexins.

Gong XQ, Nicholson BJ.

Cell Commun Adhes. 2001;8(4-6):187-92.

PMID:
12064586
32.

Application of SCAM (substituted cysteine accessibility method) to gap junction intercellular channels.

Skerrett M, Kasperek E, Cao FL, Shin JH, Aronowitz J, Ahmed S, Nicholson BJ.

Cell Commun Adhes. 2001;8(4-6):179-85.

PMID:
12064585
33.

Isolation and characterization of gap junctions from tissue culture cells.

Hand GM, Müller DJ, Nicholson BJ, Engel A, Sosinsky GE.

J Mol Biol. 2002 Jan 25;315(4):587-600.

PMID:
11812132
34.

Applying the Xenopus oocyte expression system to the analysis of gap junction proteins.

Skerrett IM, Merritt M, Zhou L, Zhu H, Cao F, Smith JF, Nicholson BJ.

Methods Mol Biol. 2001;154:225-49. No abstract available.

PMID:
11218651
35.

Connexin43 suppresses MFG-E8 while inducing contact growth inhibition of glioma cells.

Goldberg GS, Bechberger JF, Tajima Y, Merritt M, Omori Y, Gawinowicz MA, Narayanan R, Tan Y, Sanai Y, Yamasaki H, Naus CC, Tsuda H, Nicholson BJ.

Cancer Res. 2000 Nov 1;60(21):6018-26.

36.

Molecular and functional diversity of neural connexins in the retina.

Dermietzel R, Kremer M, Paputsoglu G, Stang A, Skerrett IM, Gomes D, Srinivas M, Janssen-Bienhold U, Weiler R, Nicholson BJ, Bruzzone R, Spray DC.

J Neurosci. 2000 Nov 15;20(22):8331-43.

37.

The molecular basis of selective permeability of connexins is complex and includes both size and charge.

Nicholson BJ, Weber PA, Cao F, Chang H, Lampe P, Goldberg G.

Braz J Med Biol Res. 2000 Apr;33(4):369-78. Review.

38.

Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channels.

Suchyna TM, Nitsche JM, Chilton M, Harris AL, Veenstra RD, Nicholson BJ.

Biophys J. 1999 Dec;77(6):2968-87.

39.

Selective transfer of endogenous metabolites through gap junctions composed of different connexins.

Goldberg GS, Lampe PD, Nicholson BJ.

Nat Cell Biol. 1999 Nov;1(7):457-9. No abstract available.

PMID:
10559992
40.

Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels.

Zhou L, Kasperek EM, Nicholson BJ.

J Cell Biol. 1999 Mar 8;144(5):1033-45.

42.

Direct isolation and analysis of endogenous transjunctional ADP from Cx43 transfected C6 glioma cells.

Goldberg GS, Lampe PD, Sheedy D, Stewart CC, Nicholson BJ, Naus CC.

Exp Cell Res. 1998 Feb 25;239(1):82-92.

PMID:
9511727
43.

A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes.

Cao F, Eckert R, Elfgang C, Nitsche JM, Snyder SA, H-ulser DF, Willecke K, Nicholson BJ.

J Cell Sci. 1998 Jan;111 ( Pt 1):31-43.

44.

Molecular cloning and functional expression of mouse connexin-30,a gap junction gene highly expressed in adult brain and skin.

Dahl E, Manthey D, Chen Y, Schwarz HJ, Chang YS, Lalley PA, Nicholson BJ, Willecke K.

J Biol Chem. 1996 Jul 26;271(30):17903-10. Erratum in: J Biol Chem 1996 Oct 18;271(42):26444.

45.

Structure of gap junction intercellular channels.

Yeager M, Nicholson BJ.

Curr Opin Struct Biol. 1996 Apr;6(2):183-92. Review.

PMID:
8728651
46.
47.

Proliferation-associated differences in the spatial and temporal expression of gap junction genes in rat liver.

Neveu MJ, Hully JR, Babcock KL, Vaughan J, Hertzberg EL, Nicholson BJ, Paul DL, Pitot HC.

Hepatology. 1995 Jul;22(1):202-12.

PMID:
7601414
48.

Differences in the expression of connexin genes in rat hepatomas in vivo and in vitro.

Neveu MJ, Sattler CA, Sattler GL, Hully JR, Hertzberg EL, Paul DL, Nicholson BJ, Pitot HC.

Mol Carcinog. 1994 Nov;11(3):145-54.

PMID:
7945803
49.

Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters.

Neveu MJ, Babcock KL, Hertzberg EL, Paul DL, Nicholson BJ, Pitot HC.

Cancer Res. 1994 Jun 15;54(12):3145-52.

50.

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