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Items: 24


Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon.

Cantorna MT, Lin YD, Arora J, Bora S, Tian Y, Nichols RG, Patterson AD.

Front Immunol. 2019 Jul 30;10:1772. doi: 10.3389/fimmu.2019.01772. eCollection 2019.


A Quantitative HILIC-MS/MS Assay of the Metabolic Response of Huh-7 Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.

Liu Q, Cai J, Nichols RG, Tian Y, Zhang J, Smith PB, Wang Y, Yan C, Patterson AD.

Metabolites. 2019 Jun 20;9(6). pii: E118. doi: 10.3390/metabo9060118.


Interplay Between the Host, the Human Microbiome, and Drug Metabolism.

Nichols RG, Peters JM, Patterson AD.

Hum Genomics. 2019 Jun 11;13(1):27. doi: 10.1186/s40246-019-0211-9. Review.


Multiplatform Physiologic and Metabolic Phenotyping Reveals Microbial Toxicity.

Cai J, Nichols RG, Koo I, Kalikow ZA, Zhang L, Tian Y, Zhang J, Smith PB, Patterson AD.

mSystems. 2018 Nov 6;3(6). pii: e00123-18. doi: 10.1128/mSystems.00123-18. eCollection 2018 Nov-Dec.


Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation.

Tian Y, Cai J, Gui W, Nichols RG, Koo I, Zhang J, Anitha M, Patterson AD.

Drug Metab Dispos. 2019 Feb;47(2):86-93. doi: 10.1124/dmd.118.083691. Epub 2018 Nov 8.


Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.

Sun L, Xie C, Wang G, Wu Y, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C.

Nat Med. 2018 Dec;24(12):1919-1929. doi: 10.1038/s41591-018-0222-4. Epub 2018 Nov 5.


Structural and Functional Analysis of the Gut Microbiome for Toxicologists.

Nichols RG, Cai J, Murray IA, Koo I, Smith PB, Perdew GH, Patterson AD.

Curr Protoc Toxicol. 2018 Nov;78(1):e54. doi: 10.1002/cptx.54. Epub 2018 Sep 19.


The aryl hydrocarbon receptor as a moderator of host-microbiota communication.

Zhang L, Nichols RG, Patterson AD.

Curr Opin Toxicol. 2017 Feb;2:30-35. doi: 10.1016/j.cotox.2017.02.001. Epub 2017 Feb 12.


Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.

Pathak P, Xie C, Nichols RG, Ferrell JM, Boehme S, Krausz KW, Patterson AD, Gonzalez FJ, Chiang JYL.

Hepatology. 2018 Oct;68(4):1574-1588. doi: 10.1002/hep.29857. Epub 2018 May 21.


Dietary Broccoli Impacts Microbial Community Structure and Attenuates Chemically Induced Colitis in Mice in an Ah receptor dependent manner.

Hubbard TD, Murray IA, Nichols RG, Cassel K, Podolsky M, Kuzu G, Tian Y, Smith P, Kennett MJ, Patterson AD, Perdew GH.

J Funct Foods. 2017 Oct;37:685-698. doi: 10.1016/j.jff.2017.08.038. Epub 2017 Sep 1.


Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis.

Tian Y, Nichols RG, Cai J, Patterson AD, Cantorna MT.

J Nutr Biochem. 2018 Apr;54:28-34. doi: 10.1016/j.jnutbio.2017.10.011. Epub 2017 Nov 5.


Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.

Li G, Xie C, Lu S, Nichols RG, Tian Y, Li L, Patel D, Ma Y, Brocker CN, Yan T, Krausz KW, Xiang R, Gavrilova O, Patterson AD, Gonzalez FJ.

Cell Metab. 2017 Nov 7;26(5):801. doi: 10.1016/j.cmet.2017.10.007. No abstract available.


Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.

Li G, Xie C, Lu S, Nichols RG, Tian Y, Li L, Patel D, Ma Y, Brocker CN, Yan T, Krausz KW, Xiang R, Gavrilova O, Patterson AD, Gonzalez FJ.

Cell Metab. 2017 Oct 3;26(4):672-685.e4. doi: 10.1016/j.cmet.2017.08.019. Epub 2017 Sep 14. Erratum in: Cell Metab. 2017 Nov 7;26(5):801.


Farnesoid X Receptor Signaling Shapes the Gut Microbiota and Controls Hepatic Lipid Metabolism.

Zhang L, Xie C, Nichols RG, Chan SH, Jiang C, Hao R, Smith PB, Cai J, Simons MN, Hatzakis E, Maranas CD, Gonzalez FJ, Patterson AD.

mSystems. 2016 Oct 11;1(5). pii: e00070-16. eCollection 2016 Sep-Oct.


Omics Approaches To Probe Microbiota and Drug Metabolism Interactions.

Nichols RG, Hume NE, Smith PB, Peters JM, Patterson AD.

Chem Res Toxicol. 2016 Dec 19;29(12):1987-1997. Epub 2016 Oct 26. Review.


Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice.

Murray IA, Nichols RG, Zhang L, Patterson AD, Perdew GH.

Sci Rep. 2016 Sep 23;6:33969. doi: 10.1038/srep33969.


Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.

Zhang L, Hatzakis E, Nichols RG, Hao R, Correll J, Smith PB, Chiaro CR, Perdew GH, Patterson AD.

Environ Sci Technol. 2015 Jul 7;49(13):8067-77. doi: 10.1021/acs.est.5b01389. Epub 2015 Jun 12.


Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.

Zhang L, Nichols RG, Correll J, Murray IA, Tanaka N, Smith PB, Hubbard TD, Sebastian A, Albert I, Hatzakis E, Gonzalez FJ, Perdew GH, Patterson AD.

Environ Health Perspect. 2015 Jul;123(7):679-88. doi: 10.1289/ehp.1409055. Epub 2015 Mar 13.


Modulation of colon cancer by nutmeg.

Li F, Yang XW, Krausz KW, Nichols RG, Xu W, Patterson AD, Gonzalez FJ.

J Proteome Res. 2015 Apr 3;14(4):1937-46. doi: 10.1021/pr5013152. Epub 2015 Mar 10.


Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.

Jiang C, Xie C, Li F, Zhang L, Nichols RG, Krausz KW, Cai J, Qi Y, Fang ZZ, Takahashi S, Tanaka N, Desai D, Amin SG, Albert I, Patterson AD, Gonzalez FJ.

J Clin Invest. 2015 Jan;125(1):386-402. doi: 10.1172/JCI76738. Epub 2014 Dec 15.


Drug proficiency test false positives: a lack of critical thought.

Nichols RG.

Sci Justice. 1997 Jul-Sep;37(3):191-6.


Meningeal worm-induced neurologic disease in black-tailed deer.

Nettles VF, Prestwood AK, Nichols RG, Whitehead CJ.

J Wildl Dis. 1977 Apr;13(2):137-43.


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