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Delays in anti-hyperglycaemic therapy initiation and intensification are associated with cardiovascular events, hospitalizations for heart failure and all-cause mortality.

Nichols GA, Romo-LeTourneau V, Vupputuri S, Thomas SM.

Diabetes Obes Metab. 2019 Jul;21(7):1551-1557. doi: 10.1111/dom.13683. Epub 2019 Apr 8.


Insomnia is associated with an increased risk of type 2 diabetes in the clinical setting.

LeBlanc ES, Smith NX, Nichols GA, Allison MJ, Clarke GN.

BMJ Open Diabetes Res Care. 2018 Dec 26;6(1):e000604. doi: 10.1136/bmjdrc-2018-000604. eCollection 2018.


Increased residual cardiovascular risk in patients with diabetes and high versus normal triglycerides despite statin-controlled LDL cholesterol.

Nichols GA, Philip S, Reynolds K, Granowitz CB, Fazio S.

Diabetes Obes Metab. 2019 Feb;21(2):366-371. doi: 10.1111/dom.13537. Epub 2018 Oct 14.


The Effect of Age and Comorbidities on the Association Between the Medicare STAR Oral Antihyperglycemic Adherence Metric and Glycemic Control.

Nichols GA, Raebel MA, Dyer W, Schmittdiel JA.

J Manag Care Spec Pharm. 2018 Sep;24(9):856-861. doi: 10.18553/jmcp.2018.24.9.856.


Comparison of Medical Care Utilization and Costs Among Patients With Statin-Controlled Low-Density Lipoprotein Cholesterol With Versus Without Hypertriglyceridemia.

Nichols GA, Philip S, Reynolds K, Granowitz CB, O'Keeffe-Rosetti M, Fazio S.

Am J Cardiol. 2018 Oct 1;122(7):1128-1132. doi: 10.1016/j.amjcard.2018.06.029. Epub 2018 Jul 5.


Increased Cardiovascular Risk in Hypertriglyceridemic Patients With Statin-Controlled LDL Cholesterol.

Nichols GA, Philip S, Reynolds K, Granowitz CB, Fazio S.

J Clin Endocrinol Metab. 2018 Aug 1;103(8):3019-3027. doi: 10.1210/jc.2018-00470.


Add-On Antihypertensive Medications to Angiotensin-Aldosterone System Blockers in Diabetes: A Comparative Effectiveness Study.

Schroeder EB, Chonchol M, Shetterly SM, Powers JD, Adams JL, Schmittdiel JA, Nichols GA, O'Connor PJ, Steiner JF.

Clin J Am Soc Nephrol. 2018 May 7;13(5):727-734. doi: 10.2215/CJN.09510817. Epub 2018 Mar 23.


Long-term changes in oral health-related quality of life of standard, cleft, and surgery patients after orthodontic treatment: A longitudinal study.

Nichols GAL, Antoun JS, Fowler PV, Al-Ani AH, Farella M.

Am J Orthod Dentofacial Orthop. 2018 Feb;153(2):224-231. doi: 10.1016/j.ajodo.2017.06.018.


The association between estimated glomerular filtration rate, albuminuria, and risk of cardiovascular hospitalizations and all-cause mortality among patients with type 2 diabetes.

Nichols GA, Déruaz-Luyet A, Hauske SJ, Brodovicz KG.

J Diabetes Complications. 2018 Mar;32(3):291-297. doi: 10.1016/j.jdiacomp.2017.12.003. Epub 2017 Dec 18.


A Simple Model for Predicting Two-Year Risk of Diabetes Development in Individuals with Prediabetes.

Glauber H, Vollmer WM, Nichols GA.

Perm J. 2018;22:17-050. doi: 10.7812/TPP/17-050.


Prevalence and incidence of urinary tract and genital infections among patients with and without type 2 diabetes.

Nichols GA, Brodovicz KG, Kimes TM, Déruaz-Luyet A, Bartels DB.

J Diabetes Complications. 2017 Nov;31(11):1587-1591. doi: 10.1016/j.jdiacomp.2017.07.018. Epub 2017 Aug 3.


Relationships between Medication Adherence and Cardiovascular Disease Risk Factor Control in Elderly Patients with Diabetes.

Raebel MA, Dyer W, Nichols GA, Goodrich GK, Schmittdiel JA.

Pharmacotherapy. 2017 Oct;37(10):1204-1214. doi: 10.1002/phar.1994. Epub 2017 Sep 12.


Predicting the 6-month risk of severe hypoglycemia among adults with diabetes: Development and external validation of a prediction model.

Schroeder EB, Xu S, Goodrich GK, Nichols GA, O'Connor PJ, Steiner JF.

J Diabetes Complications. 2017 Jul;31(7):1158-1163. doi: 10.1016/j.jdiacomp.2017.04.004. Epub 2017 Apr 11.


High rates of severe hypoglycemia among African American patients with diabetes: the surveillance, prevention, and Management of Diabetes Mellitus (SUPREME-DM) network.

Karter AJ, Lipska KJ, O'Connor PJ, Liu JY, Moffet HH, Schroeder EB, Lawrence JM, Nichols GA, Newton KM, Pathak RD, Desai J, Waitzfelder B, Butler MG, Thomas A, Steiner JF; SUPREME-DM Study Group.

J Diabetes Complications. 2017 May;31(5):869-873. doi: 10.1016/j.jdiacomp.2017.02.009. Epub 2017 Feb 21.


Cardiometabolic Risk Factors Among 1.3 Million Adults With Overweight or Obesity, but Not Diabetes, in 10 Geographically Diverse Regions of the United States, 2012-2013.

Nichols GA, Horberg M, Koebnick C, Young DR, Waitzfelder B, Sherwood NE, Daley MF, Ferrara A.

Prev Chronic Dis. 2017 Mar 9;14:E22. doi: 10.5888/pcd14.160438.


Effect of Combination Cholesterol-Lowering Therapy and Triglyceride-Lowering Therapy on Medical Costs in Patients With Type 2 Diabetes Mellitus.

Nichols GA, Reynolds K, Olufade T, Kimes TM, O'Keeffe-Rosetti M, Sapp DS, Anzalone D, Fortmann SP.

Am J Cardiol. 2017 Feb 1;119(3):410-415. doi: 10.1016/j.amjcard.2016.10.029. Epub 2016 Nov 4.


The Change in HbA1c Associated with Initial Adherence and Subsequent Change in Adherence among Diabetes Patients Newly Initiating Metformin Therapy.

Nichols GA, Rosales AG, Kimes TM, Tunceli K, Kurtyka K, Mavros P.

J Diabetes Res. 2016;2016:9687815. doi: 10.1155/2016/9687815. Epub 2016 Aug 7.


Medical Care Costs Associated With Long-term Weight Maintenance Versus Weight Gain Among Patients With Type 2 Diabetes.

Nichols GA, Bell K, Kimes TM, O'Keeffe-Rosetti M.

Diabetes Care. 2016 Nov;39(11):1981-1986. Epub 2016 Aug 25.


The High Prevalence of Diabetes in a Large Cohort of Patients Drawn From Safety Net Clinics.

Nichols GA, McBurnie M, Paul L, Potter JE, McCann S, Mayer K, Melgar G, D'Amato S, DeVoe JE.

Prev Chronic Dis. 2016 Jun 16;13:E78. doi: 10.5888/pcd13.160056. Erratum in: Prev Chronic Dis. 2016;13:E127.


The Patient Outcomes Research To Advance Learning (PORTAL) Network Adult Overweight and Obesity Cohort: Development and Description.

Young DR, Waitzfelder BA, Arterburn D, Nichols GA, Ferrara A, Koebnick C, Yamamoto A, Daley MF, Sherwood NE, Horberg MA, Cromwell L, Lewis KH.

JMIR Res Protoc. 2016 Jun 15;5(2):e87. doi: 10.2196/resprot.5589.


Left-ventricular geometry and risk of sudden cardiac arrest in patients with preserved or moderately reduced left-ventricular ejection fraction.

Aro AL, Reinier K, Phan D, Teodorescu C, Uy-Evanado A, Nichols GA, Gunson K, Jui J, Chugh SS.

Europace. 2017 Jul 1;19(7):1146-1152. doi: 10.1093/europace/euw126.


Severe Hypoglycemia Requiring Medical Intervention in a Large Cohort of Adults With Diabetes Receiving Care in U.S. Integrated Health Care Delivery Systems: 2005-2011.

Pathak RD, Schroeder EB, Seaquist ER, Zeng C, Lafata JE, Thomas A, Desai J, Waitzfelder B, Nichols GA, Lawrence JM, Karter AJ, Steiner JF, Segal J, O'Connor PJ; SUPREME-DM Study Group.

Diabetes Care. 2016 Mar;39(3):363-70. doi: 10.2337/dc15-0858. Epub 2015 Dec 17.


Do patient or provider characteristics impact management of diabetes?

LeBlanc ES, Rosales AG, Kachroo S, Mukherjee J, Funk KL, Nichols GA.

Am J Manag Care. 2015 Sep;21(9):597-606.


Chronic Obstructive Pulmonary Disease and Risk of Sudden Cardiac Death.

Narayanan K, Reinier K, Uy-Evanado A, Teodorescu C, Zhang L, Chugh H, Nichols GA, Gunson K, Jui J, Chugh SS.

JACC Clin Electrophysiol. 2015 Oct;1(5):381-387. doi: 10.1016/j.jacep.2015.06.005. Epub 2015 Aug 20.


Mitral valve prolapse and sudden cardiac arrest in the community.

Narayanan K, Uy-Evanado A, Teodorescu C, Reinier K, Nichols GA, Gunson K, Jui J, Chugh SS.

Heart Rhythm. 2016 Feb;13(2):498-503. doi: 10.1016/j.hrthm.2015.09.026. Epub 2015 Sep 28.


Reply: To PMID 26361825.

Nichols GA, Reynolds K.

Am J Cardiol. 2015 Nov 1;116(9):1486. doi: 10.1016/j.amjcard.2015.08.008. Epub 2015 Aug 28. No abstract available.


Weight maintenance following the STRIDE lifestyle intervention for individuals taking antipsychotic medications.

Green CA, Yarborough BJ, Leo MC, Stumbo SP, Perrin NA, Nichols GA, Stevens VJ.

Obesity (Silver Spring). 2015 Oct;23(10):1995-2001. doi: 10.1002/oby.21205. Epub 2015 Sep 3.


Who Must We Target Now to Minimize Future Cardiovascular Events and Total Mortality?: Lessons From the Surveillance, Prevention and Management of Diabetes Mellitus (SUPREME-DM) Cohort Study.

Desai JR, Vazquez-Benitez G, Xu Z, Schroeder EB, Karter AJ, Steiner JF, Nichols GA, Reynolds K, Xu S, Newton K, Pathak RD, Waitzfelder B, Lafata JE, Butler MG, Kirchner HL, Thomas A, O'Connor PJ; SUPREME-DM Study Group.

Circ Cardiovasc Qual Outcomes. 2015 Sep;8(5):508-16.


Distinctive Clinical Profile of Blacks Versus Whites Presenting With Sudden Cardiac Arrest.

Reinier K, Nichols GA, Huertas-Vazquez A, Uy-Evanado A, Teodorescu C, Stecker EC, Gunson K, Jui J, Chugh SS.

Circulation. 2015 Aug 4;132(5):380-7. doi: 10.1161/CIRCULATIONAHA.115.015673. Epub 2015 Jul 20.


Comparison of Risk of Re-hospitalization, All-Cause Mortality, and Medical Care Resource Utilization in Patients With Heart Failure and Preserved Versus Reduced Ejection Fraction.

Nichols GA, Reynolds K, Kimes TM, Rosales AG, Chan WW.

Am J Cardiol. 2015 Oct 1;116(7):1088-92. doi: 10.1016/j.amjcard.2015.07.018. Epub 2015 Jul 15.


Methods for engaging stakeholders in comparative effectiveness research: a patient-centered approach to improving diabetes care.

Schmittdiel JA, Desai J, Schroeder EB, Paolino AR, Nichols GA, Lawrence JM, O'Connor PJ, Ohnsorg KA, Newton KM, Steiner JF.

Healthc (Amst). 2015 Jun;3(2):80-8. doi: 10.1016/j.hjdsi.2015.02.005. Epub 2015 Mar 13.


An Innovative Approach to Informing Research: Gathering Perspectives on Diabetes Care Challenges From an Online Patient Community.

Schroeder EB, Desai J, Schmittdiel JA, Paolino AR, Schneider JL, Goodrich GK, Lawrence JM, Newton KM, Nichols GA, O'Connor PJ, Fitz-Randolph M, Steiner JF.

Interact J Med Res. 2015 Jun 30;4(2):e13. doi: 10.2196/ijmr.3856.


Relation of Acute Heart Failure Hospital Length of Stay to Subsequent Readmission and All-Cause Mortality.

Reynolds K, Butler MG, Kimes TM, Rosales AG, Chan W, Nichols GA.

Am J Cardiol. 2015 Aug 1;116(3):400-5. doi: 10.1016/j.amjcard.2015.04.052. Epub 2015 May 9.


Prevalence of chronic kidney disease among individuals with diabetes in the SUPREME-DM Project, 2005-2011.

Schroeder EB, Powers JD, O'Connor PJ, Nichols GA, Xu S, Desai JR, Karter AJ, Morales LS, Newton KM, Pathak RD, Vazquez-Benitez G, Raebel MA, Butler MG, Lafata JE, Reynolds K, Thomas A, Waitzfelder BE, Steiner JF; SUPREME-DM Study Group.

J Diabetes Complications. 2015 Jul;29(5):637-43. doi: 10.1016/j.jdiacomp.2015.04.007. Epub 2015 Apr 16.


Impact on glycated haemoglobin of a biological response-based measure of medication adherence.

Nichols GA, Rosales AG, Kimes TM, Tunceli K, Kurtyka K, Mavros P, Steiner JF.

Diabetes Obes Metab. 2015 Sep;17(9):843-8. doi: 10.1111/dom.12476. Epub 2015 May 20.


Provider beliefs about diabetes treatment have little impact on glycemic control of their patients with diabetes.

LeBlanc ES, Rosales AG, Kachroo S, Mukherjee J, Funk KL, Schneider JL, Nichols GA.

BMJ Open Diabetes Res Care. 2015 Feb 24;3(1):e000062. doi: 10.1136/bmjdrc-2014-000062. eCollection 2015.


Health care system-level factors associated with performance on Medicare STAR adherence metrics in a large, integrated delivery system.

Schmittdiel JA, Nichols GA, Dyer W, Steiner JF, Karter AJ, Raebel MA.

Med Care. 2015 Apr;53(4):332-7. doi: 10.1097/MLR.0000000000000328.


Preventable major cardiovascular events associated with uncontrolled glucose, blood pressure, and lipids and active smoking in adults with diabetes with and without cardiovascular disease: a contemporary analysis.

Vazquez-Benitez G, Desai JR, Xu S, Goodrich GK, Schroeder EB, Nichols GA, Segal J, Butler MG, Karter AJ, Steiner JF, Newton KM, Morales LS, Pathak RD, Thomas A, Reynolds K, Kirchner HL, Waitzfelder B, Elston Lafata J, Adibhatla R, Xu Z, O'Connor PJ.

Diabetes Care. 2015 May;38(5):905-12. doi: 10.2337/dc14-1877. Epub 2015 Feb 20.


Trends in diabetes incidence among 7 million insured adults, 2006-2011: the SUPREME-DM project.

Nichols GA, Schroeder EB, Karter AJ, Gregg EW, Desai J, Lawrence JM, O'Connor PJ, Xu S, Newton KM, Raebel MA, Pathak RD, Waitzfelder B, Segal J, Lafata JE, Butler MG, Kirchner HL, Thomas A, Steiner JF; SUPREME-DM Study Group.

Am J Epidemiol. 2015 Jan 1;181(1):32-9. doi: 10.1093/aje/kwu255. Epub 2014 Dec 16.


Diabetes care and outcomes for American Indians and Alaska natives in commercial integrated delivery systems: a SUrveillance, PREvention, and ManagEment of Diabetes Mellitus (SUPREME-DM) Study.

Schmittdiel JA, Steiner JF, Adams AS, Dyer W, Beals J, Henderson WG, Desai J, Morales LS, Nichols GA, Lawrence JM, Waitzfelder B, Butler MG, Pathak RD, Hamman RF, Manson SM.

BMJ Open Diabetes Res Care. 2014 Nov 17;2(1):e000043. doi: 10.1136/bmjdrc-2014-000043. eCollection 2014.


Left ventricular diameter and risk stratification for sudden cardiac death.

Narayanan K, Reinier K, Teodorescu C, Uy-Evanado A, Aleong R, Chugh H, Nichols GA, Gunson K, London B, Jui J, Chugh SS.

J Am Heart Assoc. 2014 Sep 16;3(5):e001193. doi: 10.1161/JAHA.114.001193.


The STRIDE weight loss and lifestyle intervention for individuals taking antipsychotic medications: a randomized trial.

Green CA, Yarborough BJ, Leo MC, Yarborough MT, Stumbo SP, Janoff SL, Perrin NA, Nichols GA, Stevens VJ.

Am J Psychiatry. 2015 Jan;172(1):71-81. doi: 10.1176/appi.ajp.2014.14020173. Epub 2014 Oct 31.


Impact of implementing glycated hemoglobin testing for identification of dysglycemia in youth.

Vijayadeva V, Nichols GA.

Perm J. 2014 Fall;18(4):21-7. doi: 10.7812/TPP/14-029. Epub 2014 Aug 18.


Misclassification in assessment of diabetogenic risk using electronic health records.

Winterstein AG, Kubilis P, Bird S, Cooper-DeHoff RM, Nichols GA, Delaney JA.

Pharmacoepidemiol Drug Saf. 2014 Aug;23(8):875-81. doi: 10.1002/pds.3656. Epub 2014 Jun 12.


Prescription medication burden in patients with newly diagnosed diabetes: a SUrveillance, PREvention, and ManagEment of Diabetes Mellitus (SUPREME-DM) study.

Schmittdiel JA, Raebel MA, Dyer W, Xu S, Goodrich GK, Schroeder EB, Segal JB, O' Connor PJ, Nichols GA, Lawrence JM, Kirchner HL, Karter AJ, Lafata JE, Butler MG, Steiner JF.

J Am Pharm Assoc (2003). 2014 Jul-Aug;54(4):374-82.


Intensification of antihyperglycemic therapy among patients with incident diabetes: a Surveillance Prevention and Management of Diabetes Mellitus (SUPREME-DM) study.

Raebel MA, Ellis JL, Schroeder EB, Xu S, O'Connor PJ, Segal JB, Butler MG, Schmittdiel JA, Kirchner HL, Goodrich GK, Lawrence JM, Nichols GA, Newton KM, Pathak RD, Steiner JF.

Pharmacoepidemiol Drug Saf. 2014 Jul;23(7):699-710. doi: 10.1002/pds.3610. Epub 2014 Mar 18.


Initial antihyperglycemic drug therapy among 241 327 adults with newly identified diabetes from 2005 through 2010: a surveillance, prevention, and management of diabetes mellitus (SUPREME-DM) study.

Raebel MA, Xu S, Goodrich GK, Schroeder EB, Schmittdiel JA, Segal JB, O'Connor PJ, Nichols GA, Lawrence JM, Kirchner HL, Elston Lafata J, Butler M, Newton KM, Steiner JF.

Ann Pharmacother. 2013 Oct;47(10):1280-91. doi: 10.1177/1060028013503624.


The economic burden of progressive chronic kidney disease among patients with type 2 diabetes.

Vupputuri S, Kimes TM, Calloway MO, Christian JB, Bruhn D, Martin AA, Nichols GA.

J Diabetes Complications. 2014 Jan-Feb;28(1):10-6. doi: 10.1016/j.jdiacomp.2013.09.014. Epub 2013 Oct 7.


The association between different A1C-based measures of glycemia and risk of cardiovascular disease hospitalization.

Nichols GA, Rosales AG, Perrin NA, Fortmann SP.

Diabetes Care. 2014;37(1):167-72. doi: 10.2337/dc13-1300. Epub 2013 Aug 29.


Inhibition by local bupivacaine-releasing microspheres of acute postoperative pain from hairy skin incision.

Ohri R, Wang JC, Blaskovich PD, Pham LN, Costa DS, Nichols GA, Hildebrand WP, Scarborough NL, Herman CJ, Strichartz GR.

Anesth Analg. 2013 Sep;117(3):717-30. doi: 10.1213/ANE.0b013e3182a00851. Epub 2013 Aug 6.


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