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Diabetes Care Editors' Expert Forum 2018: Managing Big Data for Diabetes Research and Care.

Riddle MC, Blonde L, Gerstein HC, Gregg EW, Holman RR, Lachin JM, Nichols GA, Turchin A, Cefalu WT.

Diabetes Care. 2019 Jun;42(6):1136-1146. doi: 10.2337/dci19-0020.


Association between Right Ventricular Dysfunction and Sudden Cardiac Death.

Pandat S, Nagaura T, Nair SG, Uy-Evanado A, Stecker E, Nichols GA, Jui J, Shiota T, Chugh SS, Reinier K.

Heart Rhythm. 2019 Oct 18. pii: S1547-5271(19)30943-9. doi: 10.1016/j.hrthm.2019.10.021. [Epub ahead of print]


Scalable and cost-effective tosylation-mediated synthesis of antifungal and fungal diagnostic 6″-Modified amphiphilic kanamycins.

Subedi YP, Pandey U, Alfindee MN, Montgomery H, Roberts P, Wight J, Nichols G, Grilley M, Takemoto JY, Chang CT.

Eur J Med Chem. 2019 Nov 15;182:111639. doi: 10.1016/j.ejmech.2019.111639. Epub 2019 Aug 22.


Identifying Common Predictors of Multiple Adverse Outcomes Among Elderly Adults With Type-2 Diabetes.

Kabue S, Liu V, Dyer W, Raebel M, Nichols G, Schmittdiel J.

Med Care. 2019 Sep;57(9):702-709. doi: 10.1097/MLR.0000000000001159.


Examining the influence of weather on rotavirus infection.

Nichols GL, Lo Iacono G.

Lancet Planet Health. 2019 Jun;3(6):e236-e237. doi: 10.1016/S2542-5196(19)30093-2. No abstract available.


Evolution of interlayer and intralayer magnetism in three atomically thin chromium trihalides.

Kim HH, Yang B, Li S, Jiang S, Jin C, Tao Z, Nichols G, Sfigakis F, Zhong S, Li C, Tian S, Cory DG, Miao GX, Shan J, Mak KF, Lei H, Sun K, Zhao L, Tsen AW.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11131-11136. doi: 10.1073/pnas.1902100116. Epub 2019 May 20.


Exploring Campylobacter seasonality across Europe using The European Surveillance System (TESSy), 2008 to 2016.

Lake IR, Colón-González FJ, Takkinen J, Rossi M, Sudre B, Dias JG, Tavoschi L, Joshi A, Semenza JC, Nichols G.

Euro Surveill. 2019 Mar;24(13). doi: 10.2807/1560-7917.ES.2019.24.13.180028.


Seasonality and the effects of weather on Campylobacter infections.

Djennad A, Lo Iacono G, Sarran C, Lane C, Elson R, Höser C, Lake IR, Colón-González FJ, Kovats S, Semenza JC, Bailey TC, Kessel A, Fleming LE, Nichols GL.

BMC Infect Dis. 2019 Mar 13;19(1):255. doi: 10.1186/s12879-019-3840-7.


Delays in anti-hyperglycaemic therapy initiation and intensification are associated with cardiovascular events, hospitalizations for heart failure and all-cause mortality.

Nichols GA, Romo-LeTourneau V, Vupputuri S, Thomas SM.

Diabetes Obes Metab. 2019 Jul;21(7):1551-1557. doi: 10.1111/dom.13683. Epub 2019 Apr 8.


Association between adenovirus viral load and mortality in pediatric allo-HCT recipients: the multinational AdVance study.

Zecca M, Wynn R, Dalle JH, Feuchtinger T, Vainorius E, Brundage TM, Chandak A, Mozaffari E, Nichols G, Locatelli F.

Bone Marrow Transplant. 2019 Oct;54(10):1632-1642. doi: 10.1038/s41409-019-0483-7. Epub 2019 Feb 25.


Insomnia is associated with an increased risk of type 2 diabetes in the clinical setting.

LeBlanc ES, Smith NX, Nichols GA, Allison MJ, Clarke GN.

BMJ Open Diabetes Res Care. 2018 Dec 26;6(1):e000604. doi: 10.1136/bmjdrc-2018-000604. eCollection 2018.


Incidence of Adenovirus Infection in Hematopoietic Stem Cell Transplantation Recipients: Findings from the AdVance Study.

Sedláček P, Petterson T, Robin M, Sivaprakasam P, Vainorius E, Brundage T, Chandak A, Mozaffari E, Nichols G, Voigt S.

Biol Blood Marrow Transplant. 2019 Apr;25(4):810-818. doi: 10.1016/j.bbmt.2018.12.753. Epub 2018 Dec 20.


Current practices in the management of adenovirus infection in allogeneic hematopoietic stem cell transplant recipients in Europe: The AdVance study.

González-Vicent M, Verna M, Pochon C, Chandak A, Vainorius E, Brundage T, Mozaffari E, Nichols G, Rao K.

Eur J Haematol. 2019 Mar;102(3):210-217. doi: 10.1111/ejh.13194. Epub 2019 Jan 11.


50 Years of the Radiation Exposure Information and Reporting System.

Hagemeyer D, Nichols G, Mumma MT, Boice JD, Brock TA.

Int J Radiat Biol. 2018 Oct 25:1-4. doi: 10.1080/09553002.2018.1540896. [Epub ahead of print]


Increased residual cardiovascular risk in patients with diabetes and high versus normal triglycerides despite statin-controlled LDL cholesterol.

Nichols GA, Philip S, Reynolds K, Granowitz CB, Fazio S.

Diabetes Obes Metab. 2019 Feb;21(2):366-371. doi: 10.1111/dom.13537. Epub 2018 Oct 14.


The Effect of Age and Comorbidities on the Association Between the Medicare STAR Oral Antihyperglycemic Adherence Metric and Glycemic Control.

Nichols GA, Raebel MA, Dyer W, Schmittdiel JA.

J Manag Care Spec Pharm. 2018 Sep;24(9):856-861. doi: 10.18553/jmcp.2018.24.9.856.


Pathogen seasonality and links with weather in England and Wales: a big data time series analysis.

Cherrie MPC, Nichols G, Iacono GL, Sarran C, Hajat S, Fleming LE.

BMC Public Health. 2018 Aug 28;18(1):1067. doi: 10.1186/s12889-018-5931-6.


Comparison of Medical Care Utilization and Costs Among Patients With Statin-Controlled Low-Density Lipoprotein Cholesterol With Versus Without Hypertriglyceridemia.

Nichols GA, Philip S, Reynolds K, Granowitz CB, O'Keeffe-Rosetti M, Fazio S.

Am J Cardiol. 2018 Oct 1;122(7):1128-1132. doi: 10.1016/j.amjcard.2018.06.029. Epub 2018 Jul 5.


A Toddler With Diarrhea and Bloody Emesis Presenting to the Emergency Department.

Nichols G, Yusuf S.

Clin Pediatr (Phila). 2018 Oct;57(12):1472-1476. doi: 10.1177/0009922818780691. Epub 2018 Jun 17. No abstract available.


Increased Cardiovascular Risk in Hypertriglyceridemic Patients With Statin-Controlled LDL Cholesterol.

Nichols GA, Philip S, Reynolds K, Granowitz CB, Fazio S.

J Clin Endocrinol Metab. 2018 Aug 1;103(8):3019-3027. doi: 10.1210/jc.2018-00470.


A comparison of weather variables linked to infectious disease patterns using laboratory addresses and patient residence addresses.

Djennad A, Lo Iacono G, Sarran C, Fleming LE, Kessel A, Haines A, Nichols GL.

BMC Infect Dis. 2018 Apr 27;18(1):198. doi: 10.1186/s12879-018-3106-9.


Add-On Antihypertensive Medications to Angiotensin-Aldosterone System Blockers in Diabetes: A Comparative Effectiveness Study.

Schroeder EB, Chonchol M, Shetterly SM, Powers JD, Adams JL, Schmittdiel JA, Nichols GA, O'Connor PJ, Steiner JF.

Clin J Am Soc Nephrol. 2018 May 7;13(5):727-734. doi: 10.2215/CJN.09510817. Epub 2018 Mar 23.


Long-term changes in oral health-related quality of life of standard, cleft, and surgery patients after orthodontic treatment: A longitudinal study.

Nichols GAL, Antoun JS, Fowler PV, Al-Ani AH, Farella M.

Am J Orthod Dentofacial Orthop. 2018 Feb;153(2):224-231. doi: 10.1016/j.ajodo.2017.06.018.


Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors.

Nemunaitis J, Young A, Ejadi S, Miller W, Chen LC, Nichols G, Blotner S, Vazvaei F, Zhi J, Razak A.

Cancer Chemother Pharmacol. 2018 Mar;81(3):529-537. doi: 10.1007/s00280-018-3521-z. Epub 2018 Jan 24.


The association between estimated glomerular filtration rate, albuminuria, and risk of cardiovascular hospitalizations and all-cause mortality among patients with type 2 diabetes.

Nichols GA, Déruaz-Luyet A, Hauske SJ, Brodovicz KG.

J Diabetes Complications. 2018 Mar;32(3):291-297. doi: 10.1016/j.jdiacomp.2017.12.003. Epub 2017 Dec 18.


A Simple Model for Predicting Two-Year Risk of Diabetes Development in Individuals with Prediabetes.

Glauber H, Vollmer WM, Nichols GA.

Perm J. 2018;22:17-050. doi: 10.7812/TPP/17-050.


Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy.

Pan R, Ruvolo V, Mu H, Leverson JD, Nichols G, Reed JC, Konopleva M, Andreeff M.

Cancer Cell. 2017 Dec 11;32(6):748-760.e6. doi: 10.1016/j.ccell.2017.11.003.


Kinetics of Double-Stranded DNA Viremia After Allogeneic Hematopoietic Cell Transplantation.

Hill JA, Mayer BT, Xie H, Leisenring WM, Huang ML, Stevens-Ayers T, Milano F, Delaney C, Jerome KR, Zerr DM, Nichols G, Boeckh M, Schiffer JT.

Clin Infect Dis. 2018 Jan 18;66(3):368-375. doi: 10.1093/cid/cix804.


Environmental Suitability of Vibrio Infections in a Warming Climate: An Early Warning System.

Semenza JC, Trinanes J, Lohr W, Sudre B, Löfdahl M, Martinez-Urtaza J, Nichols GL, Rocklöv J.

Environ Health Perspect. 2017 Oct 10;125(10):107004. doi: 10.1289/EHP2198.


Genetic polymorphisms associated with the risk of concussion in 1056 college athletes: a multicentre prospective cohort study.

Terrell TR, Abramson R, Barth JT, Bennett E, Cantu RC, Sloane R, Laskowitz DT, Erlanger DM, McKeag D, Nichols G, Valentine V, Galloway L.

Br J Sports Med. 2018 Feb;52(3):192-198. doi: 10.1136/bjsports-2016-097419. Epub 2017 Sep 16.


Prevalence and incidence of urinary tract and genital infections among patients with and without type 2 diabetes.

Nichols GA, Brodovicz KG, Kimes TM, Déruaz-Luyet A, Bartels DB.

J Diabetes Complications. 2017 Nov;31(11):1587-1591. doi: 10.1016/j.jdiacomp.2017.07.018. Epub 2017 Aug 3.


Relationships between Medication Adherence and Cardiovascular Disease Risk Factor Control in Elderly Patients with Diabetes.

Raebel MA, Dyer W, Nichols GA, Goodrich GK, Schmittdiel JA.

Pharmacotherapy. 2017 Oct;37(10):1204-1214. doi: 10.1002/phar.1994. Epub 2017 Sep 12.


Challenges in developing methods for quantifying the effects of weather and climate on water-associated diseases: A systematic review.

Lo Iacono G, Armstrong B, Fleming LE, Elson R, Kovats S, Vardoulakis S, Nichols GL.

PLoS Negl Trop Dis. 2017 Jun 12;11(6):e0005659. doi: 10.1371/journal.pntd.0005659. eCollection 2017 Jun. Review.


Predicting the 6-month risk of severe hypoglycemia among adults with diabetes: Development and external validation of a prediction model.

Schroeder EB, Xu S, Goodrich GK, Nichols GA, O'Connor PJ, Steiner JF.

J Diabetes Complications. 2017 Jul;31(7):1158-1163. doi: 10.1016/j.jdiacomp.2017.04.004. Epub 2017 Apr 11.


High rates of severe hypoglycemia among African American patients with diabetes: the surveillance, prevention, and Management of Diabetes Mellitus (SUPREME-DM) network.

Karter AJ, Lipska KJ, O'Connor PJ, Liu JY, Moffet HH, Schroeder EB, Lawrence JM, Nichols GA, Newton KM, Pathak RD, Desai J, Waitzfelder B, Butler MG, Thomas A, Steiner JF; SUPREME-DM Study Group.

J Diabetes Complications. 2017 May;31(5):869-873. doi: 10.1016/j.jdiacomp.2017.02.009. Epub 2017 Feb 21.


Cardiometabolic Risk Factors Among 1.3 Million Adults With Overweight or Obesity, but Not Diabetes, in 10 Geographically Diverse Regions of the United States, 2012-2013.

Nichols GA, Horberg M, Koebnick C, Young DR, Waitzfelder B, Sherwood NE, Daley MF, Ferrara A.

Prev Chronic Dis. 2017 Mar 9;14:E22. doi: 10.5888/pcd14.160438.


The cumulative burden of double-stranded DNA virus detection after allogeneic HCT is associated with increased mortality.

Hill JA, Mayer BT, Xie H, Leisenring WM, Huang ML, Stevens-Ayers T, Milano F, Delaney C, Sorror ML, Sandmaier BM, Nichols G, Zerr DM, Jerome KR, Schiffer JT, Boeckh M.

Blood. 2017 Apr 20;129(16):2316-2325. doi: 10.1182/blood-2016-10-748426. Epub 2017 Feb 16.


Association between heavy precipitation events and waterborne outbreaks in four Nordic countries, 1992-2012.

Guzman Herrador B, de Blasio BF, Carlander A, Ethelberg S, Hygen HO, Kuusi M, Lund V, Löfdahl M, MacDonald E, Martinez-Urtaza J, Nichols G, Schönning C, Sudre B, Trönnberg L, Vold L, Semenza JC, Nygård K.

J Water Health. 2016 Dec;14(6):1019-1027.


Effect of Combination Cholesterol-Lowering Therapy and Triglyceride-Lowering Therapy on Medical Costs in Patients With Type 2 Diabetes Mellitus.

Nichols GA, Reynolds K, Olufade T, Kimes TM, O'Keeffe-Rosetti M, Sapp DS, Anzalone D, Fortmann SP.

Am J Cardiol. 2017 Feb 1;119(3):410-415. doi: 10.1016/j.amjcard.2016.10.029. Epub 2016 Nov 4.


Definitions of Cytomegalovirus Infection and Disease in Transplant Patients for Use in Clinical Trials.

Ljungman P, Boeckh M, Hirsch HH, Josephson F, Lundgren J, Nichols G, Pikis A, Razonable RR, Miller V, Griffiths PD; Disease Definitions Working Group of the Cytomegalovirus Drug Development Forum.

Clin Infect Dis. 2017 Jan 1;64(1):87-91. Epub 2016 Sep 28.


A Unified Framework for the Infection Dynamics of Zoonotic Spillover and Spread.

Lo Iacono G, Cunningham AA, Fichet-Calvet E, Garry RF, Grant DS, Leach M, Moses LM, Nichols G, Schieffelin JS, Shaffer JG, Webb CT, Wood JL.

PLoS Negl Trop Dis. 2016 Sep 2;10(9):e0004957. doi: 10.1371/journal.pntd.0004957. eCollection 2016 Sep.


The Change in HbA1c Associated with Initial Adherence and Subsequent Change in Adherence among Diabetes Patients Newly Initiating Metformin Therapy.

Nichols GA, Rosales AG, Kimes TM, Tunceli K, Kurtyka K, Mavros P.

J Diabetes Res. 2016;2016:9687815. doi: 10.1155/2016/9687815. Epub 2016 Aug 7.


Medical Care Costs Associated With Long-term Weight Maintenance Versus Weight Gain Among Patients With Type 2 Diabetes.

Nichols GA, Bell K, Kimes TM, O'Keeffe-Rosetti M.

Diabetes Care. 2016 Nov;39(11):1981-1986. Epub 2016 Aug 25.


The High Prevalence of Diabetes in a Large Cohort of Patients Drawn From Safety Net Clinics.

Nichols GA, McBurnie M, Paul L, Potter JE, McCann S, Mayer K, Melgar G, D'Amato S, DeVoe JE.

Prev Chronic Dis. 2016 Jun 16;13:E78. doi: 10.5888/pcd13.160056. Erratum in: Prev Chronic Dis. 2016;13:E127.


The Patient Outcomes Research To Advance Learning (PORTAL) Network Adult Overweight and Obesity Cohort: Development and Description.

Young DR, Waitzfelder BA, Arterburn D, Nichols GA, Ferrara A, Koebnick C, Yamamoto A, Daley MF, Sherwood NE, Horberg MA, Cromwell L, Lewis KH.

JMIR Res Protoc. 2016 Jun 15;5(2):e87. doi: 10.2196/resprot.5589.


Left-ventricular geometry and risk of sudden cardiac arrest in patients with preserved or moderately reduced left-ventricular ejection fraction.

Aro AL, Reinier K, Phan D, Teodorescu C, Uy-Evanado A, Nichols GA, Gunson K, Jui J, Chugh SS.

Europace. 2017 Jul 1;19(7):1146-1152. doi: 10.1093/europace/euw126.


Acute myeloid leukemia patients' clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts.

Reis B, Jukofsky L, Chen G, Martinelli G, Zhong H, So WV, Dickinson MJ, Drummond M, Assouline S, Hashemyan M, Theron M, Blotner S, Lee JH, Kasner M, Yoon SS, Rueger R, Seiter K, Middleton SA, Kelly KR, Vey N, Yee K, Nichols G, Chen LC, Pierceall WE.

Haematologica. 2016 May;101(5):e185-8. doi: 10.3324/haematol.2015.139717. Epub 2016 Feb 11. No abstract available.


Severe Hypoglycemia Requiring Medical Intervention in a Large Cohort of Adults With Diabetes Receiving Care in U.S. Integrated Health Care Delivery Systems: 2005-2011.

Pathak RD, Schroeder EB, Seaquist ER, Zeng C, Lafata JE, Thomas A, Desai J, Waitzfelder B, Nichols GA, Lawrence JM, Karter AJ, Steiner JF, Segal J, O'Connor PJ; SUPREME-DM Study Group.

Diabetes Care. 2016 Mar;39(3):363-70. doi: 10.2337/dc15-0858. Epub 2015 Dec 17.


Do patient or provider characteristics impact management of diabetes?

LeBlanc ES, Rosales AG, Kachroo S, Mukherjee J, Funk KL, Nichols GA.

Am J Manag Care. 2015 Sep;21(9):597-606.


Cyclospora infection linked to travel to Mexico, June to September 2015.

Nichols GL, Freedman J, Pollock KG, Rumble C, Chalmers RM, Chiodini P, Hawkins G, Alexander CL, Godbole G, Williams C, Kirkbride HA, Hamel M, Hawker JI.

Euro Surveill. 2015;20(43). doi: 10.2807/1560-7917.ES.2015.20.43.30048.

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