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Items: 1 to 50 of 121

1.

Antibacterial Spectrum of a Tetrazole-Based Reversible Inhibitor of Serine β-Lactamases.

Pemberton OA, Zhang X, Nichols DA, DeFrees K, Jaishankar P, Bonnet R, Adams J, Shaw LN, Renslo AR, Chen Y.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e02563-17. doi: 10.1128/AAC.02563-17. Print 2018 Aug.

2.

Correction to: Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis.

Nichols DA, Sondh IS, Little SR, Zunino P, Gottardi R.

Biomed Microdevices. 2018 May 8;20(2):39. doi: 10.1007/s10544-018-0283-7.

PMID:
29736756
3.

Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis.

Nichols DA, Sondh IS, Little SR, Zunino P, Gottardi R.

Biomed Microdevices. 2018 Feb 14;20(1):18. doi: 10.1007/s10544-018-0264-x. Erratum in: Biomed Microdevices. 2018 May 8;20(2):39.

4.

Predictors of sleepiness in obstructive sleep apnoea at baseline and after 6 months of continuous positive airway pressure therapy.

Budhiraja R, Kushida CA, Nichols DA, Walsh JK, Simon RD, Gottlieb DJ, Quan SF.

Eur Respir J. 2017 Nov 30;50(5). pii: 1700348. doi: 10.1183/13993003.00348-2017. Print 2017 Nov.

5.

Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine.

Dempsey DR, Nichols DA, Battistini MR, Pemberton O, Ospina SR, Zhang X, Carpenter AM, O'Flynn BG, Leahy JW, Kanwar A, Lewandowski EM, Chen Y, Merkler DJ.

Sci Rep. 2017 Oct 18;7(1):13432. doi: 10.1038/s41598-017-13669-6.

6.

Impact of continuous positive airway pressure (CPAP) on quality of life in patients with obstructive sleep apnea (OSA).

Batool-Anwar S, Goodwin JL, Kushida CA, Walsh JA, Simon RD, Nichols DA, Quan SF.

J Sleep Res. 2016 Dec;25(6):731-738. doi: 10.1111/jsr.12430. Epub 2016 May 30.

7.

In vitro efficacy of 2,N-bisarylated 2-ethoxyacetamides against Plasmodium falciparum.

Gutteridge CE, Major JW, Nin DA, Curtis SM, Bhattacharjee AK, Gerena L, Nichols DA.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):1048-1051. doi: 10.1016/j.bmcl.2015.12.032. Epub 2015 Dec 11.

PMID:
26750257
8.

Impact of Randomization, Clinic Visits, and Medical and Psychiatric Cormorbidities on Continuous Positive Airway Pressure Adherence in Obstructive Sleep Apnea.

Budhiraja R, Kushida CA, Nichols DA, Walsh JK, Simon RD, Gottlieb DJ, Quan SF.

J Clin Sleep Med. 2016 Mar;12(3):333-41. doi: 10.5664/jcsm.5578.

9.

Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.

Nichols DA, Hargis JC, Sanishvili R, Jaishankar P, Defrees K, Smith EW, Wang KK, Prati F, Renslo AR, Woodcock HL, Chen Y.

J Am Chem Soc. 2015 Jul 1;137(25):8086-95. doi: 10.1021/jacs.5b00749. Epub 2015 Jun 22.

10.

SMART DOCS: a new patient-centered outcomes and coordinated-care management approach for the future practice of sleep medicine.

Kushida CA, Nichols DA, Holmes TH, Miller R, Griffin K, Cardell CY, Hyde PR, Cohen E, Manber R, Walsh JK.

Sleep. 2015 Feb 1;38(2):315-26. doi: 10.5665/sleep.4422.

11.

Fragment-based inhibitor discovery against β-lactamase.

Nichols DA, Renslo AR, Chen Y.

Future Med Chem. 2014 Mar;6(4):413-27. doi: 10.4155/fmc.14.10. Review.

12.

You still need more than CPAP for OSA patients to lose weight.

Quan SF, Budhiraja R, Clarke DP, Goodwin JL, Gottlieb DJ, Nichols DA, Simon RD, Smith TW, Walsh JK, Kushida CA, Phillips B.

J Clin Sleep Med. 2014 Mar 15;10(3):349. doi: 10.5664/jcsm.3552. No abstract available.

13.

A single-institution experience in image-guided thermal ablation of adrenal gland metastases.

Welch BT, Callstrom MR, Carpenter PC, Wass CT, Welch TL, Boorjian SA, Nichols DA, Thompson GB, Lohse CM, Erickson D, Leibovich BC, Atwell TD.

J Vasc Interv Radiol. 2014 Apr;25(4):593-8. doi: 10.1016/j.jvir.2013.12.013. Epub 2014 Feb 6.

PMID:
24507995
14.

The COMET Sleep Research Platform.

Nichols DA, DeSalvo S, Miller RA, Jónsson D, Griffin KS, Hyde PR, Walsh JK, Kushida CA.

EGEMS (Wash DC). 2014 Nov 24;2(1):1059. doi: 10.13063/2327-9214.1059. eCollection 2014.

15.

Reproducibility of bracket positioning in the indirect bonding technique.

Nichols DA, Gardner G, Carballeyra AD.

Am J Orthod Dentofacial Orthop. 2013 Nov;144(5):770-6. doi: 10.1016/j.ajodo.2013.04.023.

PMID:
24182593
16.

Impact of treatment with continuous positive airway pressure (CPAP) on weight in obstructive sleep apnea.

Quan SF, Budhiraja R, Clarke DP, Goodwin JL, Gottlieb DJ, Nichols DA, Simon RD, Smith TW, Walsh JK, Kushida CA.

J Clin Sleep Med. 2013 Oct 15;9(10):989-93. doi: 10.5664/jcsm.3064.

17.

Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES).

Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD Jr, Guilleminault C, White DP, Goodwin JL, Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC.

Sleep. 2012 Dec 1;35(12):1593-602. doi: 10.5665/sleep.2226. Erratum in: Sleep. 2016 Jul 1;39(7):1483.

18.

Strategies for de-identification and anonymization of electronic health record data for use in multicenter research studies.

Kushida CA, Nichols DA, Jadrnicek R, Miller R, Walsh JK, Griffin K.

Med Care. 2012 Jul;50 Suppl:S82-101. doi: 10.1097/MLR.0b013e3182585355. Review.

19.

Structure-based design of potent and ligand-efficient inhibitors of CTX-M class A β-lactamase.

Nichols DA, Jaishankar P, Larson W, Smith E, Liu G, Beyrouthy R, Bonnet R, Renslo AR, Chen Y.

J Med Chem. 2012 Mar 8;55(5):2163-72. doi: 10.1021/jm2014138. Epub 2012 Feb 14.

PMID:
22296601
20.

A method for estimating normative distributions for study-specific populations of clinical trials.

Holmes TH, Nichols DA, Thomander D, Kushida CA.

Contemp Clin Trials. 2012 Mar;33(2):445-9. doi: 10.1016/j.cct.2011.11.014. Epub 2011 Nov 25.

21.

Frame-dragging vortexes and tidal tendexes attached to colliding black holes: visualizing the curvature of spacetime.

Owen R, Brink J, Chen Y, Kaplan JD, Lovelace G, Matthews KD, Nichols DA, Scheel MA, Zhang F, Zimmerman A, Thorne KS.

Phys Rev Lett. 2011 Apr 15;106(15):151101. Epub 2011 Apr 11.

PMID:
21568540
22.

The association between obstructive sleep apnea and neurocognitive performance--the Apnea Positive Pressure Long-term Efficacy Study (APPLES).

Quan SF, Chan CS, Dement WC, Gevins A, Goodwin JL, Gottlieb DJ, Green S, Guilleminault C, Hirshkowitz M, Hyde PR, Kay GG, Leary EB, Nichols DA, Schweitzer PK, Simon RD, Walsh JK, Kushida CA.

Sleep. 2011 Mar 1;34(3):303-314B.

23.

In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones.

Gutteridge CE, Thota DS, Curtis SM, Kozar MP, Li Q, Xie L, Zhang J, Melendez V, Asher CO, Luong TT, Gerena L, Nichols DA, Montip G.

Pharmacology. 2011;87(1-2):96-104. doi: 10.1159/000322532. Epub 2011 Feb 1.

PMID:
21282967
24.

Percutaneous image-guided adrenal cryoablation: procedural considerations and technical success.

Welch BT, Atwell TD, Nichols DA, Wass CT, Callstrom MR, Leibovich BC, Carpenter PC, Mandrekar JN, Charboneau JW.

Radiology. 2011 Jan;258(1):301-7. doi: 10.1148/radiol.10100631. Epub 2010 Oct 22.

PMID:
20971772
25.

Mayo Clinic was first.

Nichols DA.

Minn Med. 2010 Feb;93(2):6. No abstract available.

PMID:
20302226
26.

Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones.

Geyer JA, Keenan SM, Woodard CL, Thompson PA, Gerena L, Nichols DA, Gutteridge CE, Waters NC.

Bioorg Med Chem Lett. 2009 Apr 1;19(7):1982-5. doi: 10.1016/j.bmcl.2009.02.042. Epub 2009 Feb 13.

PMID:
19250824
27.

Coils or clips in subarachnoid hemorrhage?

Nichols DA, Brown RD Jr, Meyer FB.

J Stroke Cerebrovasc Dis. 2002 Nov-Dec;11(6):295-6; discussion 296-7. No abstract available.

PMID:
17903889
28.

An in silico 3D pharmacophore model of chalcones useful in the design of novel antimalarial agents.

Bhattacharjee AK, Nichols DA, Gerena L, Roncal N, Gutteridge CE.

Med Chem. 2007 Jul;3(4):317-26.

PMID:
17627568
29.

The Apnea Positive Pressure Long-term Efficacy Study (APPLES): rationale, design, methods, and procedures.

Kushida CA, Nichols DA, Quan SF, Goodwin JL, White DP, Gottlieb DJ, Walsh JK, Schweitzer PK, Guilleminault C, Simon RD, Leary EB, Hyde PR, Holmes TH, Bloch DA, Green S, McEvoy LK, Gevins A, Dement WC.

J Clin Sleep Med. 2006 Jul 15;2(3):288-300.

PMID:
17561541
30.

Antileishmanial and antimalarial chalcones: synthesis, efficacy and cytotoxicity of pyridinyl and naphthalenyl analogs.

Gutteridge CE, Vo JV, Tillett CB, Vigilante JA, Dettmer JR, Patterson SL, Werbovetz KA, Capers J, Nichols DA, Bhattacharjee AK, Gerena L.

Med Chem. 2007 Mar;3(2):115-9.

PMID:
17348849
31.

In vitro and in vivo efficacy and in vitro metabolism of 1-phenyl-3-aryl-2-propen-1-ones against Plasmodium falciparum.

Gutteridge CE, Nichols DA, Curtis SM, Thota DS, Vo JV, Gerena L, Montip G, Asher CO, Diaz DS, Ditusa CA, Smith KS, Bhattacharjee AK.

Bioorg Med Chem Lett. 2006 Nov 1;16(21):5682-6. Epub 2006 Aug 14.

PMID:
16908136
32.

Clinical presentation and surgical management of dissecting posterior inferior cerebellar artery aneurysms: 2 case reports.

Wetjen NM, Link MJ, Reimer R, Nichols DA, Giannini C.

Surg Neurol. 2005 Nov;64(5):462-7; discussion 467.

PMID:
16253703
33.

Survival of cardiac arrest after aneurysmal subarachnoid hemorrhage.

Toussaint LG 3rd, Friedman JA, Wijdicks EF, Piepgras DG, Pichelmann MA, McIver JI, McClelland RL, Nichols DA, Meyer FB, Atkinson JL.

Neurosurgery. 2005 Jul;57(1):25-31; discussion 25-31.

PMID:
15987537
34.

The medicinal chemistry of botulinum, ricin and anthrax toxins.

Hicks RP, Hartell MG, Nichols DA, Bhattacharjee AK, van Hamont JE, Skillman DR.

Curr Med Chem. 2005;12(6):667-90. Review.

PMID:
15790305
35.

Influence of aspirin on outcome following aneurysmal subarachnoid hemorrhage.

Toussaint LG 3rd, Friedman JA, Wijdicks EF, Piepgras DG, Pichelmann MA, McIver JI, McClelland RL, Nichols DA, Meyer FB, Atkinson JL.

J Neurosurg. 2004 Dec;101(6):921-5.

PMID:
15597751
36.

Cost of treating high-risk symptomatic carotid artery stenosis: stent insertion and angioplasty compared with endarterectomy.

Ecker RD, Brown RD Jr, Nichols DA, McClelland RL, Reinalda MS, Piepgras DG, Cloft HJ, Kallmes DF.

J Neurosurg. 2004 Dec;101(6):904-7.

PMID:
15597748
38.

Predictors of outcome after endovascular treatment of cerebral vasospasm.

Rabinstein AA, Friedman JA, Nichols DA, Pichelmann MA, McClelland RL, Manno EM, Atkinson JL, Wijdicks EF.

AJNR Am J Neuroradiol. 2004 Nov-Dec;25(10):1778-82.

39.

A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.

Bhattacharjee AK, Geyer JA, Woodard CL, Kathcart AK, Nichols DA, Prigge ST, Li Z, Mott BT, Waters NC.

J Med Chem. 2004 Oct 21;47(22):5418-26.

PMID:
15481979
41.
42.

Restless legs syndrome symptoms in primary care: a prevalence study.

Nichols DA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC, Kushida CA.

Arch Intern Med. 2003 Oct 27;163(19):2323-9.

PMID:
14581252
43.

Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.

Woodard CL, Li Z, Kathcart AK, Terrell J, Gerena L, Lopez-Sanchez M, Kyle DE, Bhattacharjee AK, Nichols DA, Ellis W, Prigge ST, Geyer JA, Waters NC.

J Med Chem. 2003 Aug 28;46(18):3877-82.

PMID:
12930149
44.

Transcutaneous coil, stent, and balloon migration following endovascular treatment of a cervical carotid artery aneurysm. Case illustration.

Collignon FP, Friedman JA, Piepgras DG, Nichols DA, Cloft H.

J Neurosurg. 2003 May;98(5):1135. No abstract available.

PMID:
12744381
45.

Pulmonary complications of aneurysmal subarachnoid hemorrhage.

Friedman JA, Pichelmann MA, Piepgras DG, McIver JI, Toussaint LG 3rd, McClelland RL, Nichols DA, Meyer FB, Atkinson JL, Wijdicks EF.

Neurosurgery. 2003 May;52(5):1025-31; discussion 1031-2.

PMID:
12699543
46.

Comparison of the conformation and electrostatic surface properties of magainin peptides bound to sodium dodecyl sulfate and dodecylphosphocholine micelles.

Hicks RP, Mones E, Kim H, Koser BW, Nichols DA, Bhattacharjee AK.

Biopolymers. 2003 Apr;68(4):459-70.

PMID:
12666172
47.

Guglielmi detachable coil treatment of ruptured saccular cerebral aneurysms: retrospective review of a 10-year single-center experience.

Friedman JA, Nichols DA, Meyer FB, Pichelmann MA, McIver JI, Toussaint LG 3rd, Axley PL, Brown RD Jr.

AJNR Am J Neuroradiol. 2003 Mar;24(3):526-33.

48.

Symptomatic vasospasm and outcomes following aneurysmal subarachnoid hemorrhage: a comparison between surgical repair and endovascular coil occlusion.

Rabinstein AA, Pichelmann MA, Friedman JA, Piepgras DG, Nichols DA, McIver JI, Toussaint LG 3rd, McClelland RL, Fulgham JR, Meyer FB, Atkinson JL, Wijdicks EF.

J Neurosurg. 2003 Feb;98(2):319-25.

PMID:
12593618
49.

Delayed ischemic deficit after resection of a large intracranial dermoid: case report and review of the literature.

Ecker RD, Atkinson JL, Nichols DA.

Neurosurgery. 2003 Mar;52(3):706-10; discussion 709-10. Review.

PMID:
12590698
50.

Development of a pontine cyst after endovascular coil occlusion of a basilar artery trunk aneurysm: case report.

Friedman JA, McIver JI, Collignon FP, Nichols DA, Piepgras DG.

Neurosurgery. 2003 Mar;52(3):694-9; discussion 698-9.

PMID:
12590696

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