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Items: 40

1.

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.

Parsons MT, Tudini E, Li H, Hahnen E, Wappenschmidt B, Feliubadaló L, Aalfs CM, Agata S, Aittomäki K, Alducci E, Alonso-Cerezo MC, Arnold N, Auber B, Austin R, Azzollini J, Balmaña J, Barbieri E, Bartram CR, Blanco A, Blümcke B, Bonache S, Bonanni B, Borg Å, Bortesi B, Brunet J, Bruzzone C, Bucksch K, Cagnoli G, Caldés T, Caliebe A, Caligo MA, Calvello M, Capone GL, Caputo SM, Carnevali I, Carrasco E, Caux-Moncoutier V, Cavalli P, Cini G, Clarke EM, Concolino P, Cops EJ, Cortesi L, Couch FJ, Darder E, de la Hoya M, Dean M, Debatin I, Del Valle J, Delnatte C, Derive N, Diez O, Ditsch N, Domchek SM, Dutrannoy V, Eccles DM, Ehrencrona H, Enders U, Evans DG, Faust U, Felbor U, Feroce I, Fine M, Galvao HCR, Gambino G, Gehrig A, Gensini F, Gerdes AM, Germani A, Giesecke J, Gismondi V, Gómez C, Gómez Garcia EB, González S, Grau E, Grill S, Gross E, Guerrieri-Gonzaga A, Guillaud-Bataille M, Gutiérrez-Enríquez S, Haaf T, Hackmann K, Hansen TVO, Harris M, Hauke J, Heinrich T, Hellebrand H, Herold KN, Honisch E, Horvath J, Houdayer C, Hübbel V, Iglesias S, Izquierdo A, James PA, Janssen LAM, Jeschke U, Kaulfuß S, Keupp K, Kiechle M, Kölbl A, Krieger S, Kruse TA, Kvist A, Lalloo F, Larsen M, Lattimore VL, Lautrup C, Ledig S, Leinert E, Lewis AL, Lim J, Loeffler M, López-Fernández A, Lucci-Cordisco E, Maass N, Manoukian S, Marabelli M, Matricardi L, Meindl A, Michelli RD, Moghadasi S, Moles-Fernández A, Montagna M, Montalban G, Monteiro AN, Montes E, Mori L, Moserle L, Müller CR, Mundhenke C, Naldi N, Nathanson KL, Navarro M, Nevanlinna H, Nichols CB, Niederacher D, Nielsen HR, Ong KR, Pachter N, Palmero EI, Papi L, Pedersen IS, Peissel B, Pérez-Segura P, Pfeifer K, Pineda M, Pohl-Rescigno E, Poplawski NK, Porfirio B, Quante AS, Ramser J, Reis RM, Revillion F, Rhiem K, Riboli B, Ritter J, Rivera D, Rofes P, Rump A, Salinas M, Sánchez de Abajo AM, Schmidt G, Schoenwiese U, Seggewiß J, Solanes A, Steinemann D, Stiller M, Stoppa-Lyonnet D, Sullivan KJ, Susman R, Sutter C, Tavtigian SV, Teo SH, Teulé A, Thomassen M, Tibiletti MG, Tognazzo S, Toland AE, Tornero E, Törngren T, Torres-Esquius S, Toss A, Trainer AH, van Asperen CJ, van Mackelenbergh MT, Varesco L, Vargas-Parra G, Varon R, Vega A, Velasco Á, Vesper AS, Viel A, Vreeswijk MPG, Wagner SA, Waha A, Walker LC, Walters RJ, Wang-Gohrke S, Weber BHF, Weichert W, Wieland K, Wiesmüller L, Witzel I, Wöckel A, Woodward ER, Zachariae S, Zampiga V, Zeder-Göß C; KConFab Investigators, Lázaro C, De Nicolo A, Radice P, Engel C, Schmutzler RK, Goldgar DE, Spurdle AB.

Hum Mutat. 2019 May 27. doi: 10.1002/humu.23818. [Epub ahead of print]

PMID:
31131967
2.

Uptake of testing for germline BRCA mutations in patients with non-mucinous epithelial ovarian cancers in Western Australia: a comparison of different genetic counseling methods.

Stearnes G, Nichols CB, Schofield L, O'Sullivan S, Pachter N, Cohen PA.

Int J Gynecol Cancer. 2019 May 17. pii: ijgc-2019-000389. doi: 10.1136/ijgc-2019-000389. [Epub ahead of print]

PMID:
31101686
3.

Wortmannin and Wortmannine Analogues from an Undescribed Niesslia sp.

Dischler NM, Xu L, Li Y, Nichols CB, Alspaugh JA, Bills GF, Gloer JB.

J Nat Prod. 2019 Mar 22;82(3):532-538. doi: 10.1021/acs.jnatprod.8b00923. Epub 2019 Mar 7.

PMID:
30844268
4.

Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition.

Esher SK, Ost KS, Kohlbrenner MA, Pianalto KM, Telzrow CL, Campuzano A, Nichols CB, Munro C, Wormley FL Jr, Alspaugh JA.

PLoS Pathog. 2018 Jun 4;14(6):e1007126. doi: 10.1371/journal.ppat.1007126. eCollection 2018 Jun.

5.

HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence.

Brandão F, Esher SK, Ost KS, Pianalto K, Nichols CB, Fernandes L, Bocca AL, Poças-Fonseca MJ, Alspaugh JA.

Sci Rep. 2018 Mar 26;8(1):5209. doi: 10.1038/s41598-018-21965-y.

6.

Investigating barriers to genetic counseling and germline mutation testing in women with suspected hereditary breast and ovarian cancer syndrome and Lynch syndrome.

Shaw J, Bulsara C, Cohen PA, Gryta M, Nichols CB, Schofield L, O'Sullivan S, Pachter N, Hardcastle SJ.

Patient Educ Couns. 2018 May;101(5):938-944. doi: 10.1016/j.pec.2017.12.011. Epub 2017 Dec 12.

PMID:
29273311
7.

Prognostic Role of Histological Tumor Regression in Patients Receiving Neoadjuvant Chemotherapy for High-Grade Serous Tubo-ovarian Carcinoma.

Coghlan E, Meniawy TM, Munro A, Bulsara M, Stewart CJ, Tan A, Koay ME, MaGee D, Codde J, Tan J, Salfinger SG, Mohan GR, Leung Y, Nichols CB, Cohen PA.

Int J Gynecol Cancer. 2017 May;27(4):708-713. doi: 10.1097/IGC.0000000000000945.

PMID:
30814178
8.

Prognostic Role of Histological Tumor Regression in Patients Receiving Neoadjuvant Chemotherapy for High-Grade Serous Tubo-ovarian Carcinoma.

Coghlan E, Meniawy TM, Munro A, Bulsara M, Stewart CJ, Tan A, Koay MHE, MaGee D, Codde J, Tan J, Salfinger SG, Mohan GR, Leung Y, Nichols CB, Cohen PA.

Int J Gynecol Cancer. 2017 May;27(4):708-713. doi: 10.1097/IGC.0000000000000945.

PMID:
28441251
9.

Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis.

Esher SK, Ost KS, Kozubowski L, Yang DH, Kim MS, Bahn YS, Alspaugh JA, Nichols CB.

mSphere. 2016 Mar 30;1(2). pii: e00084-15. doi: 10.1128/mSphere.00084-15. eCollection 2016 Mar-Apr.

10.

Impact of Clinical Genetics Attendance at a Gynecologic Oncology Tumor Board on Referrals for Genetic Counseling and BRCA Mutation Testing.

Cohen PA, Nichols CB, Schofield L, Van Der Werf S, Pachter N.

Int J Gynecol Cancer. 2016 Jun;26(5):892-7. doi: 10.1097/IGC.0000000000000689.

PMID:
27051053
11.

S-Nitrosylation Induces Both Autonomous Activation and Inhibition of Calcium/Calmodulin-dependent Protein Kinase II δ.

Erickson JR, Nichols CB, Uchinoumi H, Stein ML, Bossuyt J, Bers DM.

J Biol Chem. 2015 Oct 16;290(42):25646-56. doi: 10.1074/jbc.M115.650234. Epub 2015 Aug 27.

12.

Use of Orbital Conformer to Improve Speech in Patients with Confluent Maxillectomy and Orbital Defects.

Colebeck AC, Kase MT, Nichols CB, Golden M, Huryn JM.

J Prosthodont. 2016 Apr;25(3):241-6. doi: 10.1111/jopr.12282. Epub 2015 May 7.

13.

Impact of Protein Palmitoylation on the Virulence Potential of Cryptococcus neoformans.

Nichols CB, Ost KS, Grogan DP, Pianalto K, Hasan S, Alspaugh JA.

Eukaryot Cell. 2015 Jul;14(7):626-35. doi: 10.1128/EC.00010-15. Epub 2015 Apr 10.

14.

β-adrenergic signaling inhibits Gq-dependent protein kinase D activation by preventing protein kinase D translocation.

Nichols CB, Chang CW, Ferrero M, Wood BM, Stein ML, Ferguson AJ, Ha D, Rigor RR, Bossuyt S, Bossuyt J.

Circ Res. 2014 Apr 25;114(9):1398-409. doi: 10.1161/CIRCRESAHA.114.303870. Epub 2014 Mar 18. Erratum in: Circ Res. 2017 Apr 14;120(8):e32.

15.

AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus.

Nystoriak MA, Nieves-Cintrón M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF.

Circ Res. 2014 Feb 14;114(4):607-15. doi: 10.1161/CIRCRESAHA.114.302168. Epub 2013 Dec 9.

16.

Restricted substrate specificity for the geranylgeranyltransferase-I enzyme in Cryptococcus neoformans: implications for virulence.

Selvig K, Ballou ER, Nichols CB, Alspaugh JA.

Eukaryot Cell. 2013 Nov;12(11):1462-71. doi: 10.1128/EC.00193-13. Epub 2013 Sep 6.

17.

Ras1 acts through duplicated Cdc42 and Rac proteins to regulate morphogenesis and pathogenesis in the human fungal pathogen Cryptococcus neoformans.

Ballou ER, Kozubowski L, Nichols CB, Alspaugh JA.

PLoS Genet. 2013;9(8):e1003687. doi: 10.1371/journal.pgen.1003687. Epub 2013 Aug 8.

18.

Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans.

Ballou ER, Selvig K, Narloch JL, Nichols CB, Alspaugh JA.

Fungal Genet Biol. 2013 Aug;57:58-75. doi: 10.1016/j.fgb.2013.05.006. Epub 2013 Jun 5.

19.

Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation.

Jones BW, Brunet S, Gilbert ML, Nichols CB, Su T, Westenbroek RE, Scott JD, Catterall WA, McKnight GS.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17099-104. doi: 10.1073/pnas.1215219109. Epub 2012 Oct 3.

20.

Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens.

Hast MA, Nichols CB, Armstrong SM, Kelly SM, Hellinga HW, Alspaugh JA, Beese LS.

J Biol Chem. 2011 Oct 7;286(40):35149-62. doi: 10.1074/jbc.M111.250506. Epub 2011 Aug 4.

21.

Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels.

Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS.

Circ Res. 2010 Sep 17;107(6):747-56. doi: 10.1161/CIRCRESAHA.109.216127. Epub 2010 Jul 29.

22.

Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.

Weisenhaus M, Allen ML, Yang L, Lu Y, Nichols CB, Su T, Hell JW, McKnight GS.

PLoS One. 2010 Apr 23;5(4):e10325. doi: 10.1371/journal.pone.0010325.

23.

Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule.

O'Meara TR, Norton D, Price MS, Hay C, Clements MF, Nichols CB, Alspaugh JA.

PLoS Pathog. 2010 Feb 19;6(2):e1000776. doi: 10.1371/journal.ppat.1000776.

24.

Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions.

Ballou ER, Nichols CB, Miglia KJ, Kozubowski L, Alspaugh JA.

Mol Microbiol. 2010 Feb;75(3):763-80. doi: 10.1111/j.1365-2958.2009.07019.x. Epub 2009 Dec 16.

25.

Subcellular localization directs signaling specificity of the Cryptococcus neoformans Ras1 protein.

Nichols CB, Ferreyra J, Ballou ER, Alspaugh JA.

Eukaryot Cell. 2009 Feb;8(2):181-9. doi: 10.1128/EC.00351-08. Epub 2008 Dec 19.

26.

The Cryptococcus neoformans Rho-GDP dissociation inhibitor mediates intracellular survival and virulence.

Price MS, Nichols CB, Alspaugh JA.

Infect Immun. 2008 Dec;76(12):5729-37. doi: 10.1128/IAI.00896-08. Epub 2008 Sep 8.

27.
28.

Activation of NFATc3 down-regulates the beta1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension.

Nieves-Cintrón M, Amberg GC, Nichols CB, Molkentin JD, Santana LF.

J Biol Chem. 2007 Feb 2;282(5):3231-40. Epub 2006 Dec 5.

29.

Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans.

Cramer KL, Gerrald QD, Nichols CB, Price MS, Alspaugh JA.

Eukaryot Cell. 2006 Jul;5(7):1147-56.

30.

Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity.

Campbell LT, Fraser JA, Nichols CB, Dietrich FS, Carter D, Heitman J.

Eukaryot Cell. 2005 Aug;4(8):1410-9.

31.
32.
33.

The GIN4 family kinase, Cdr2p, acts independently of septins in fission yeast.

Morrell JL, Nichols CB, Gould KL.

J Cell Sci. 2004 Oct 15;117(Pt 22):5293-302. Epub 2004 Sep 28.

34.

PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans.

Nichols CB, Fraser JA, Heitman J.

Mol Biol Cell. 2004 Oct;15(10):4476-89. Epub 2004 Jul 28.

36.
37.

Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans.

Wang P, Nichols CB, Lengeler KB, Cardenas ME, Cox GM, Perfect JR, Heitman J.

Eukaryot Cell. 2002 Apr;1(2):257-72.

38.

Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans.

Waugh MS, Nichols CB, DeCesare CM, Cox GM, Heitman J, Alspaugh JA.

Microbiology. 2002 Jan;148(Pt 1):191-201.

PMID:
11782511
39.

Competitive inhibition of a glutamate carboxypeptidase by phosphonamidothionate derivatives of glutamic acid.

Rodriguez CE, Lu H, Dinh TT, Mlodnosky KL, Dastgah A, Lam VQ, Nichols CB, Berkman CE.

Bioorg Med Chem Lett. 1999 May 17;9(10):1415-8.

PMID:
10360747
40.

Concerning Osteopathy.

Lobingier AS, Nichols CB, Fulton D, Kress GH.

Cal State J Med. 1910 Sep;8(9):318. No abstract available.

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