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Items: 1 to 50 of 83

1.

Predictors of plate extrusion in oromandibular free flap reconstruction.

Prasad J, Sahovaler A, Theurer J, Yeh DH, Fung K, MacNeil SD, Yoo J, Nichols AC.

Microsurgery. 2018 Jun 29. doi: 10.1002/micr.30349. [Epub ahead of print]

PMID:
29956850
2.

High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines.

Ghasemi F, Black M, Sun RX, Vizeacoumar F, Pinto N, Ruicci KM, Yoo J, Fung K, MacNeil D, Palma DA, Winquist E, Mymryk JS, Ailles LA, Datti A, Barrett JW, Boutros PC, Nichols AC.

Oncotarget. 2018 May 25;9(40):26064-26071. doi: 10.18632/oncotarget.25436. eCollection 2018 May 25.

3.

The impact of seasonal operating room closures on wait times for oral cancer surgery.

Mundi N, Theurer J, Warner A, Yoo J, Fung K, MacNeil D, Dhaliwal S, Winquist E, Palma DA, Nichols AC.

Curr Oncol. 2018 Feb;25(1):67-72. doi: 10.3747/co.25.3726. Epub 2018 Feb 28.

4.

Treatment of early stage Supraglottic squamous cell carcinoma: meta-analysis comparing primary surgery versus primary radiotherapy.

Patel KB, Nichols AC, Fung K, Yoo J, MacNeil SD.

J Otolaryngol Head Neck Surg. 2018 Mar 5;47(1):19. doi: 10.1186/s40463-018-0262-2.

5.

The prevalence of human papillomavirus in pediatric tonsils: a systematic review of the literature.

Wojtera M, Paradis J, Husein M, Nichols AC, Barrett JW, Salvadori MI, Strychowsky JE.

J Otolaryngol Head Neck Surg. 2018 Jan 30;47(1):8. doi: 10.1186/s40463-018-0255-1. Review.

6.

The incidence and management of non-head and neck incidentalomas for the head and neck surgeon.

Sahovaler A, Yeh DH, Morrison D, de Ribaupierre S, Izawa J, Power A, Inculet R, Parry N, Palma DA, Landis M, Leung A, Fung K, MacNeil SD, Yoo J, Nichols AC.

Oral Oncol. 2017 Nov;74:98-104. doi: 10.1016/j.oraloncology.2017.09.004. Epub 2017 Oct 2. Review. No abstract available.

PMID:
29103759
7.

Human papillomavirus dysregulates the cellular apparatus controlling the methylation status of H3K27 in different human cancers to consistently alter gene expression regardless of tissue of origin.

Gameiro SF, Kolendowski B, Zhang A, Barrett JW, Nichols AC, Torchia J, Mymryk JS.

Oncotarget. 2017 Aug 3;8(42):72564-72576. doi: 10.18632/oncotarget.19885. eCollection 2017 Sep 22.

8.

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer.

Ghasemi F, Black M, Vizeacoumar F, Pinto N, Ruicci KM, Le CCSH, Lowerison MR, Leong HS, Yoo J, Fung K, MacNeil D, Palma DA, Winquist E, Mymryk JS, Boutros PC, Datti A, Barrett JW, Nichols AC.

Oncotarget. 2017 Apr 20;8(42):71512-71519. doi: 10.18632/oncotarget.17292. eCollection 2017 Sep 22.

9.

Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection.

Gameiro SF, Zhang A, Ghasemi F, Barrett JW, Nichols AC, Mymryk JS.

Viruses. 2017 Sep 10;9(9). pii: E252. doi: 10.3390/v9090252.

10.

Estimating Survival After Salvage Surgery for Recurrent Oral Cavity Cancer.

Tam S, Araslanova R, Low TH, Warner A, Yoo J, Fung K, MacNeil SD, Palma DA, Nichols AC.

JAMA Otolaryngol Head Neck Surg. 2017 Jul 1;143(7):685-690. doi: 10.1001/jamaoto.2017.0001.

11.

Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.

Papillon-Cavanagh S, Lu C, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu OM, Dhaliwal S, Stecho W, Howlett CJ, Mymryk JS, Barrett JW, Nichols AC, Allis CD, Majewski J, Jabado N.

Nat Genet. 2017 Feb;49(2):180-185. doi: 10.1038/ng.3757. Epub 2017 Jan 9.

12.

Cytokine and Growth Factor Concentrations in Canine Autologous Conditioned Serum.

Sawyere DM, Lanz OI, Dahlgren LA, Barry SL, Nichols AC, Werre SR.

Vet Surg. 2016 Jul;45(5):582-6. doi: 10.1111/vsu.12506.

PMID:
27357270
13.

Pedicled adipofascial infraclavicular flap: Elevation technique and its use for maintaining neck contour and vessel coverage after radical and modified radical neck dissection.

Yoo J, Low TH, Tam S, Partridge A, MacNeil SD, Nichols AC, Fung K.

Head Neck. 2016 Oct;38(10):1579-82. doi: 10.1002/hed.24472. Epub 2016 Apr 29.

PMID:
27126378
14.

Transoral robotic surgery vs. radiotherapy for management of oropharyngeal squamous cell carcinoma - A systematic review of the literature.

Yeh DH, Tam S, Fung K, MacNeil SD, Yoo J, Winquist E, Palma DA, Nichols AC.

Eur J Surg Oncol. 2015 Dec;41(12):1603-14. doi: 10.1016/j.ejso.2015.09.007. Epub 2015 Sep 26. Review.

PMID:
26461255
15.

Feasibility of Targeting PIK3CA Mutations in Head and Neck Squamous Cell Carcinoma.

Theurer JA, Stecho W, Yoo J, Kwan K, Wehrli B, Harry V, Black M, Pinto N, Winquist E, Palma D, Richter S, Barrett JW, Danielle MacNeil S, Fung K, Howlett CJ, Nichols AC.

Pathol Oncol Res. 2016 Jan;22(1):35-40. doi: 10.1007/s12253-015-9970-3. Epub 2015 Aug 14.

PMID:
26271341
16.

Exploiting high-throughput cell line drug screening studies to identify candidate therapeutic agents in head and neck cancer.

Nichols AC, Black M, Yoo J, Pinto N, Fernandes A, Haibe-Kains B, Boutros PC, Barrett JW.

BMC Pharmacol Toxicol. 2014 Nov 27;15:66. doi: 10.1186/2050-6511-15-66.

17.

Genomically driven precision medicine to improve outcomes in anaplastic thyroid cancer.

Pinto N, Black M, Patel K, Yoo J, Mymryk JS, Barrett JW, Nichols AC.

J Oncol. 2014;2014:936285. doi: 10.1155/2014/936285. Epub 2014 Sep 7. Review.

18.

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

Weinreb I, Piscuoglio S, Martelotto LG, Waggott D, Ng CK, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, da Cruz Paula A, Marchio C, Sakr RA, Lim R, Thompson LD, Chiosea SI, Seethala RR, Skalova A, Stelow EB, Fonseca I, Assaad A, How C, Wang J, de Borja R, Chan-Seng-Yue M, Howlett CJ, Nichols AC, Wen YH, Katabi N, Buchner N, Mullen L, Kislinger T, Wouters BG, Liu FF, Norton L, McPherson JD, Rubin BP, Clarke BA, Weigelt B, Boutros PC, Reis-Filho JS.

Nat Genet. 2014 Nov;46(11):1166-9. doi: 10.1038/ng.3096. Epub 2014 Sep 21.

19.

Temporal changes in the efficacy of chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck: a systematic review and meta-analysis.

Winquist E, Al-Rasheedy I, Nichols AC, Palma DA, Stitt L.

Cancer Treat Rev. 2014 Oct;40(9):1073-9. doi: 10.1016/j.ctrv.2014.08.002. Epub 2014 Aug 27.

PMID:
25200522
20.

The control of anaplastic thyroid carcinoma cell lines by oncolytic poxviruses.

Mundi N, Um S, Yoo J, Rizzo G, Black M, Pinto N, Palma DA, Fung K, MacNeil D, Mymryk JS, Barrett JW, Nichols AC.

Virus Res. 2014 Sep 22;190:53-9. doi: 10.1016/j.virusres.2014.07.009. Epub 2014 Jul 16.

PMID:
25038405
21.

Variable expression of the forgotten oncogene E5 in HPV-positive oropharyngeal cancer.

Um SH, Mundi N, Yoo J, Palma DA, Fung K, MacNeil D, Wehrli B, Mymryk JS, Barrett JW, Nichols AC.

J Clin Virol. 2014 Sep;61(1):94-100. doi: 10.1016/j.jcv.2014.06.019. Epub 2014 Jun 30.

PMID:
25027574
22.

Defining the genomic landscape of head and neck cancers through next-generation sequencing.

Rizzo G, Black M, Mymryk JS, Barrett JW, Nichols AC.

Oral Dis. 2015 Jan;21(1):e11-24. doi: 10.1111/odi.12246. Epub 2014 Apr 30. Review.

PMID:
24725020
23.

The human papillomavirus E7 proteins associate with p190RhoGAP and alter its function.

Todorovic B, Nichols AC, Chitilian JM, Myers MP, Shepherd TG, Parsons SJ, Barrett JW, Banks L, Mymryk JS.

J Virol. 2014 Apr;88(7):3653-63. doi: 10.1128/JVI.03263-13. Epub 2014 Jan 8.

24.

Human papillomavirus in head and neck cancer.

Palma DA, Nichols AC.

CMAJ. 2014 Mar 18;186(5):370. doi: 10.1503/cmaj.130849. Epub 2013 Dec 2. Review. No abstract available.

25.

Vaccinia virus outperforms a panel of other poxviruses as a potent oncolytic agent for the control of head and neck squamous cell carcinoma cell lines.

Nichols AC, Yoo J, Um S, Mundi N, Palma DA, Fung K, Macneil SD, Koropatnick J, Mymryk JS, Barrett JW.

Intervirology. 2014;57(1):17-22. doi: 10.1159/000353854. Epub 2013 Aug 13.

26.

The epidemic of human papillomavirus and oropharyngeal cancer in a Canadian population.

Nichols AC, Palma DA, Dhaliwal SS, Tan S, Theuer J, Chow W, Rajakumar C, Um S, Mundi N, Berk S, Zhou R, Basmaji J, Rizzo G, Franklin JH, Fung K, Kwan K, Wehrli B, Salvadori MI, Winquist E, Ernst S, Kuruvilla S, Read N, Venkatesan V, Todorovic B, Hammond JA, Koropatnick J, Mymryk JS, Yoo J, Barrett JW.

Curr Oncol. 2013 Aug;20(4):212-9. doi: 10.3747/co.20.1375.

27.

High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer.

Nichols AC, Palma DA, Chow W, Tan S, Rajakumar C, Rizzo G, Fung K, Kwan K, Wehrli B, Winquist E, Koropatnick J, Mymryk JS, Yoo J, Barrett JW.

JAMA Otolaryngol Head Neck Surg. 2013 Jun;139(6):617-22. doi: 10.1001/jamaoto.2013.3210.

PMID:
23787421
28.

Viral retasking of hBre1/RNF20 to recruit hPaf1 for transcriptional activation.

Fonseca GJ, Cohen MJ, Nichols AC, Barrett JW, Mymryk JS.

PLoS Pathog. 2013;9(6):e1003411. doi: 10.1371/journal.ppat.1003411. Epub 2013 Jun 13.

29.

Does HPV type affect outcome in oropharyngeal cancer?

Nichols AC, Dhaliwal SS, Palma DA, Basmaji J, Chapeskie C, Dowthwaite S, Franklin JH, Fung K, Kwan K, Wehrli B, Howlett C, Siddiqui I, Salvadori MI, Winquist E, Ernst S, Kuruvilla S, Read N, Venkatesan V, Todorovic B, Hammond JA, Koropatnick J, Mymryk JS, Yoo J, Barrett JW.

J Otolaryngol Head Neck Surg. 2013 Feb 1;42:9. doi: 10.1186/1916-0216-42-9.

30.

Development of a transoral robotic surgery program in Canada.

Nichols AC, Fung K, Chapeskie C, Dowthwaite SA, Basmaji J, Dhaliwal S, Szeto CC, Palma DA, Theurer JA, Corsten MA, Odell M, Barrett JW, Franklin JH, Yoo J.

J Otolaryngol Head Neck Surg. 2013 Feb 1;42:8. doi: 10.1186/1916-0216-42-8.

31.

A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases.

Nichols AC, Chan-Seng-Yue M, Yoo J, Agrawal SK, Starmans MH, Waggott D, Harding NJ, Dowthwaite SA, Palma DA, Fung K, Wehrli B, Macneil SD, Lambin P, Winquist E, Koropatnick J, Mymryk JS, Boutros PC, Barrett JW.

Case Rep Oncol Med. 2013;2013:270362. doi: 10.1155/2013/270362. Epub 2013 Apr 3.

32.

The use of autologous platelet and plasma products in salvage neck dissections: a prospective clinical study evaluating early and late wound healing.

Yoo J, Chandarana S, Fung K, Franklin JH, Nichols AC, Doyle PC.

J Biol Regul Homeost Agents. 2012 Apr-Jun;26(2 Suppl 1):63S-69S.

PMID:
23648200
33.

Early-stage squamous cell carcinoma of the oropharynx: radiotherapy vs. trans-oral robotic surgery (ORATOR)--study protocol for a randomized phase II trial.

Nichols AC, Yoo J, Hammond JA, Fung K, Winquist E, Read N, Venkatesan V, MacNeil SD, Ernst DS, Kuruvilla S, Chen J, Corsten M, Odell M, Eapen L, Theurer J, Doyle PC, Wehrli B, Kwan K, Palma DA.

BMC Cancer. 2013 Mar 20;13:133. doi: 10.1186/1471-2407-13-133.

34.

Transoral robotic total laryngectomy: report of 3 cases.

Dowthwaite S, Nichols AC, Yoo J, Smith RV, Dhaliwal S, Basmaji J, Franklin JH, Fung K.

Head Neck. 2013 Nov;35(11):E338-42. doi: 10.1002/hed.23226. Epub 2013 Mar 8.

PMID:
23471833
35.

A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing.

Nichols AC, Chan-Seng-Yue M, Yoo J, Xu W, Dhaliwal S, Basmaji J, Szeto CC, Dowthwaite S, Todorovic B, Starmans MH, Lambin P, Palma DA, Fung K, Franklin JH, Wehrli B, Kwan K, Koropatnick J, Mymryk JS, Boutros P, Barrett JW.

ISRN Oncol. 2012;2012:809370. doi: 10.5402/2012/809370. Epub 2012 Dec 12.

36.

Frequent mutations in TP53 and CDKN2A found by next-generation sequencing of head and neck cancer cell lines.

Nichols AC, Yoo J, Palma DA, Fung K, Franklin JH, Koropatnick J, Mymryk JS, Batada NN, Barrett JW.

Arch Otolaryngol Head Neck Surg. 2012 Aug;138(8):732-9. doi: 10.1001/archoto.2012.1558.

PMID:
22911296
37.

The role of transoral robotic surgery in the management of oropharyngeal cancer: a review of the literature.

Dowthwaite SA, Franklin JH, Palma DA, Fung K, Yoo J, Nichols AC.

ISRN Oncol. 2012;2012:945162. doi: 10.5402/2012/945162. Epub 2012 Apr 23.

38.

Ki-67 expression predicts radiotherapy failure in early glottic cancer.

Nichols AC, Whelan F, Basmaji J, Dhaliwal S, Dowthwaite S, Chapeskie C, Read N, Palma DA, Fung K, Venkatesan V, Hammond JA, Franklin JH, Siddiqui I, Wehrli B, Kwan K, Koropatnick J, Mymryk JS, Barrett JW, Yoo J.

J Otolaryngol Head Neck Surg. 2012 Apr;41(2):124-30.

PMID:
22569013
39.

The relationship of locus of control, self-control, and acceptable noise levels for young listeners with normal hearing.

Nichols AC, Gordon-Hickey S.

Int J Audiol. 2012 Apr;51(4):353-9. doi: 10.3109/14992027.2011.645074. Epub 2012 Jan 10.

PMID:
22229761
40.

Detection of circulating tumor cells in advanced head and neck cancer using the CellSearch system.

Nichols AC, Lowes LE, Szeto CC, Basmaji J, Dhaliwal S, Chapeskie C, Todorovic B, Read N, Venkatesan V, Hammond A, Palma DA, Winquist E, Ernst S, Fung K, Franklin JH, Yoo J, Koropatnick J, Mymryk JS, Barrett JW, Allan AL.

Head Neck. 2012 Oct;34(10):1440-4. doi: 10.1002/hed.21941. Epub 2011 Nov 11.

PMID:
22076949
41.

Surgical salvage of the oropharynx after failure of organ-sparing therapy.

Nichols AC, Kneuertz PJ, Deschler DG, Lin DT, Emerick KS, Clark JR, Busse PW, Rocco JW.

Head Neck. 2011 Apr;33(4):516-24. doi: 10.1002/hed.21480.

PMID:
20652974
42.

Bcl2 and human papilloma virus 16 as predictors of outcome following concurrent chemoradiation for advanced oropharyngeal cancer.

Nichols AC, Finkelstein DM, Faquin WC, Westra WH, Mroz EA, Kneuertz P, Begum S, Michaud WA, Busse PM, Clark JR, Rocco JW.

Clin Cancer Res. 2010 Apr 1;16(7):2138-46. doi: 10.1158/1078-0432.CCR-09-3185. Epub 2010 Mar 16.

43.

An improved trypsin digestion method minimizes digestion-induced modifications on proteins.

Ren D, Pipes GD, Liu D, Shih LY, Nichols AC, Treuheit MJ, Brems DN, Bondarenko PV.

Anal Biochem. 2009 Sep 1;392(1):12-21. doi: 10.1016/j.ab.2009.05.018. Epub 2009 May 18.

PMID:
19457431
44.

The effects of chronic mercuric chloride ingestion in female Sprague-Dawley rats on fertility and reproduction.

Heath JC, Abdelmageed Y, Braden TD, Nichols AC, Steffy DA.

Food Chem Toxicol. 2009 Jul;47(7):1600-5. doi: 10.1016/j.fct.2009.04.007. Epub 2009 Apr 14.

45.

Esthesioneuroblastoma: the massachusetts eye and ear infirmary and massachusetts general hospital experience with craniofacial resection, proton beam radiation, and chemotherapy.

Nichols AC, Chan AW, Curry WT, Barker FG, Deschler DG, Lin DT.

Skull Base. 2008 Sep;18(5):327-37. doi: 10.1055/s-2008-1076098.

46.

Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma.

Michaud WA, Nichols AC, Mroz EA, Faquin WC, Clark JR, Begum S, Westra WH, Wada H, Busse PM, Ellisen LW, Rocco JW.

Clin Cancer Res. 2009 Mar 1;15(5):1645-54. doi: 10.1158/1078-0432.CCR-08-2581. Epub 2009 Feb 24.

47.

HPV-16 infection predicts treatment outcome in oropharyngeal squamous cell carcinoma.

Nichols AC, Faquin WC, Westra WH, Mroz EA, Begum S, Clark JR, Rocco JW.

Otolaryngol Head Neck Surg. 2009 Feb;140(2):228-34. doi: 10.1016/j.otohns.2008.11.025.

PMID:
19201294
48.

Automated tryptic digestion procedure for HPLC/MS/MS peptide mapping of immunoglobulin gamma antibodies in pharmaceutics.

Chelius D, Xiao G, Nichols AC, Vizel A, He B, Dillon TM, Rehder DS, Pipes GD, Kraft E, Oroska A, Treuheit MJ, Bondarenko PV.

J Pharm Biomed Anal. 2008 Jun 9;47(2):285-94. doi: 10.1016/j.jpba.2008.01.018. Epub 2008 Jan 19.

PMID:
18313251
49.

Characterization of IgG1 immunoglobulins and peptide-Fc fusion proteins by limited proteolysis in conjunction with LC-MS.

Kleemann GR, Beierle J, Nichols AC, Dillon TM, Pipes GD, Bondarenko PV.

Anal Chem. 2008 Mar 15;80(6):2001-9. doi: 10.1021/ac701629v. Epub 2008 Feb 23.

PMID:
18293943
50.

Racial differences in stage and survival in head and neck squamous cell carcinoma.

Nichols AC, Bhattacharyya N.

Laryngoscope. 2007 May;117(5):770-5.

PMID:
17473666

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