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Items: 1 to 50 of 306

1.

The impact of closing emergency departments on mortality in emergencies: an observational study.

Knowles E, Shephard N, Stone T, Mason SM, Nicholl J.

Emerg Med J. 2019 Nov;36(11):645-651. doi: 10.1136/emermed-2018-208146. Epub 2019 Oct 7.

2.

Developing new ways of measuring the quality and impact of ambulance service care: the PhOEBE mixed-methods research programme.

Turner J, Siriwardena AN, Coster J, Jacques R, Irving A, Crum A, Gorrod HB, Nicholl J, Phung VH, Togher F, Wilson R, O’Cathain A, Booth A, Bradbury D, Goodacre S, Spaight A, Shewan J, Pilbery R, Fall D, Marsh M, Broadway-Parkinson A, Lyons R, Snooks H, Campbell M.

Southampton (UK): NIHR Journals Library; 2019 Apr.

3.

Correction: A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay.

Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, Hodge JC, Gecz J, Nicholl J, McGregor L, Linden T, Sisodiya SM, Sanlaville D, Cheung SW, Ernst C, Campeau PM.

Genet Med. 2019 Sep;21(9):2159-2160. doi: 10.1038/s41436-018-0413-x.

PMID:
30643220
4.

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design.

Dimairo M, Coates E, Pallmann P, Todd S, Julious SA, Jaki T, Wason J, Mander AP, Weir CJ, Koenig F, Walton MK, Biggs K, Nicholl J, Hamasaki T, Proschan MA, Scott JA, Ando Y, Hind D, Altman DG.

BMC Med. 2018 Nov 16;16(1):210. doi: 10.1186/s12916-018-1196-2.

5.

A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay.

Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, Hodge JC, Gecz J, Nicholl J, McGregor L, Linden T, Sisodiya SM, Sanlaville D, Cheung SW, Ernst C, Campeau PM.

Genet Med. 2019 May;21(5):1058-1064. doi: 10.1038/s41436-018-0290-3. Epub 2018 Sep 24. Erratum in: Genet Med. 2019 Jan 14;:.

PMID:
30245510
6.

Closing five Emergency Departments in England between 2009 and 2011: the closED controlled interrupted time-series analysis.

Knowles E, Shephard N, Stone T, Bishop-Edwards L, Hirst E, Abouzeid L, Mason S, Nicholl J.

Southampton (UK): NIHR Journals Library; 2018 Jul.

7.

Characterising non-urgent users of the emergency department (ED): A retrospective analysis of routine ED data.

O'Keeffe C, Mason S, Jacques R, Nicholl J.

PLoS One. 2018 Feb 23;13(2):e0192855. doi: 10.1371/journal.pone.0192855. eCollection 2018.

8.

Navigation delivery models and roles of navigators in primary care: a scoping literature review.

Carter N, Valaitis RK, Lam A, Feather J, Nicholl J, Cleghorn L.

BMC Health Serv Res. 2018 Feb 8;18(1):96. doi: 10.1186/s12913-018-2889-0. Review.

9.

Benefits and challenges of using the cohort multiple randomised controlled trial design for testing an intervention for depression.

Viksveen P, Relton C, Nicholl J.

Trials. 2017 Jul 6;18(1):308. doi: 10.1186/s13063-017-2059-4.

10.
11.

YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction.

Gabriele M, Vulto-van Silfhout AT, Germain PL, Vitriolo A, Kumar R, Douglas E, Haan E, Kosaki K, Takenouchi T, Rauch A, Steindl K, Frengen E, Misceo D, Pedurupillay CRJ, Stromme P, Rosenfeld JA, Shao Y, Craigen WJ, Schaaf CP, Rodriguez-Buritica D, Farach L, Friedman J, Thulin P, McLean SD, Nugent KM, Morton J, Nicholl J, Andrieux J, Stray-Pedersen A, Chambon P, Patrier S, Lynch SA, Kjaergaard S, Tørring PM, Brasch-Andersen C, Ronan A, van Haeringen A, Anderson PJ, Powis Z, Brunner HG, Pfundt R, Schuurs-Hoeijmakers JHM, van Bon BWM, Lelieveld S, Gilissen C, Nillesen WM, Vissers LELM, Gecz J, Koolen DA, Testa G, de Vries BBA.

Am J Hum Genet. 2017 Jun 1;100(6):907-925. doi: 10.1016/j.ajhg.2017.05.006.

12.

Patient- and Family-Centered Care: First Steps on a Long Journey.

Sevransky JE, Nicholl B, Nicholl JB, Buchman TG.

Crit Care Med. 2017 May;45(5):757-758. doi: 10.1097/CCM.0000000000002431. No abstract available.

PMID:
28410305
13.

Support and Assessment for Fall Emergency Referrals (SAFER) 2: a cluster randomised trial and systematic review of clinical effectiveness and cost-effectiveness of new protocols for emergency ambulance paramedics to assess older people following a fall with referral to community-based care when appropriate.

Snooks HA, Anthony R, Chatters R, Dale J, Fothergill R, Gaze S, Halter M, Humphreys I, Koniotou M, Logan P, Lyons R, Mason S, Nicholl J, Peconi J, Phillips C, Phillips J, Porter A, Siriwardena AN, Smith G, Toghill A, Wani M, Watkins A, Whitfield R, Wilson L, Russell IT.

Health Technol Assess. 2017 Mar;21(13):1-218. doi: 10.3310/hta21130.

14.

Paramedic Assessment of Older Adults After Falls, Including Community Care Referral Pathway: Cluster Randomized Trial.

Snooks HA, Anthony R, Chatters R, Dale J, Fothergill RT, Gaze S, Halter M, Humphreys I, Koniotou M, Logan P, Lyons RA, Mason S, Nicholl J, Peconi J, Phillips C, Porter A, Siriwardena AN, Wani M, Watkins A, Wilson L, Russell IT.

Ann Emerg Med. 2017 Oct;70(4):495-505.e28. doi: 10.1016/j.annemergmed.2017.01.006. Epub 2017 Mar 13.

15.

Implementation and maintenance of patient navigation programs linking primary care with community-based health and social services: a scoping literature review.

Valaitis RK, Carter N, Lam A, Nicholl J, Feather J, Cleghorn L.

BMC Health Serv Res. 2017 Feb 6;17(1):116. doi: 10.1186/s12913-017-2046-1. Review.

16.

An evidence-based approach to the use of telehealth in long-term health conditions: development of an intervention and evaluation through pragmatic randomised controlled trials in patients with depression or raised cardiovascular risk.

Salisbury C, O’Cathain A, Thomas C, Edwards L, Montgomery AA, Hollinghurst S, Large S, Nicholl J, Pope C, Rogers A, Lewis G, Fahey T, Yardley L, Brownsell S, Dixon P, Drabble S, Esmonde L, Foster A, Garner K, Gaunt D, Horspool K, Man MS, Rowsell A, Segar J.

Southampton (UK): NIHR Journals Library; 2017 Jan.

17.

Effect of a national urgent care telephone triage service on population perceptions of urgent care provision: controlled before and after study.

Knowles E, O'Cathain A, Turner J, Nicholl J.

BMJ Open. 2016 Oct 14;6(10):e011846. doi: 10.1136/bmjopen-2016-011846.

18.

Cancer Drugs Fund requires further reform.

Grieve R, Abrams K, Claxton K, Goldacre B, James N, Nicholl J, Parmar M, Parker C, Sekhon JS, Smeeth L, Spiegelhalter D, Sculpher M.

BMJ. 2016 Sep 27;354:i5090. doi: 10.1136/bmj.i5090. No abstract available.

19.

De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females.

Palmer EE, Stuhlmann T, Weinert S, Haan E, Van Esch H, Holvoet M, Boyle J, Leffler M, Raynaud M, Moraine C, van Bokhoven H, Kleefstra T, Kahrizi K, Najmabadi H, Ropers HH, Delgado MR, Sirsi D, Golla S, Sommer A, Pietryga MP, Chung WK, Wynn J, Rohena L, Bernardo E, Hamlin D, Faux BM, Grange DK, Manwaring L, Tolmie J, Joss S; DDD Study, Cobben JM, Duijkers FAM, Goehringer JM, Challman TD, Hennig F, Fischer U, Grimme A, Suckow V, Musante L, Nicholl J, Shaw M, Lodh SP, Niu Z, Rosenfeld JA, Stankiewicz P, Jentsch TJ, Gecz J, Field M, Kalscheuer VM.

Mol Psychiatry. 2018 Feb;23(2):222-230. doi: 10.1038/mp.2016.135. Epub 2016 Aug 23.

20.

Telehealth for patients at high risk of cardiovascular disease: pragmatic randomised controlled trial.

Salisbury C, O'Cathain A, Thomas C, Edwards L, Gaunt D, Dixon P, Hollinghurst S, Nicholl J, Large S, Yardley L, Fahey T, Foster A, Garner K, Horspool K, Man MS, Rogers A, Pope C, Montgomery AA.

BMJ. 2016 Jun 1;353:i2647. doi: 10.1136/bmj.i2647.

21.

Effectiveness of an integrated telehealth service for patients with depression: a pragmatic randomised controlled trial of a complex intervention.

Salisbury C, O'Cathain A, Edwards L, Thomas C, Gaunt D, Hollinghurst S, Nicholl J, Large S, Yardley L, Lewis G, Foster A, Garner K, Horspool K, Man MS, Rogers A, Pope C, Dixon P, Montgomery AA.

Lancet Psychiatry. 2016 Jun;3(6):515-25. doi: 10.1016/S2215-0366(16)00083-3. Epub 2016 Apr 27.

22.
23.

An Investigation of the Shortcomings of the CONSORT 2010 Statement for the Reporting of Group Sequential Randomised Controlled Trials: A Methodological Systematic Review.

Stevely A, Dimairo M, Todd S, Julious SA, Nicholl J, Hind D, Cooper CL.

PLoS One. 2015 Nov 3;10(11):e0141104. doi: 10.1371/journal.pone.0141104. eCollection 2015. Review.

24.

Increased STAG2 dosage defines a novel cohesinopathy with intellectual disability and behavioral problems.

Kumar R, Corbett MA, Van Bon BW, Gardner A, Woenig JA, Jolly LA, Douglas E, Friend K, Tan C, Van Esch H, Holvoet M, Raynaud M, Field M, Leffler M, Budny B, Wisniewska M, Badura-Stronka M, Latos-Bieleńska A, Batanian J, Rosenfeld JA, Basel-Vanagaite L, Jensen C, Bienek M, Froyen G, Ullmann R, Hu H, Love MI, Haas SA, Stankiewicz P, Cheung SW, Baxendale A, Nicholl J, Thompson EM, Haan E, Kalscheuer VM, Gecz J.

Hum Mol Genet. 2015 Dec 20;24(25):7171-81. doi: 10.1093/hmg/ddv414. Epub 2015 Oct 6.

PMID:
26443594
25.

Missing steps in a staircase: a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials.

Dimairo M, Boote J, Julious SA, Nicholl JP, Todd S.

Trials. 2015 Sep 28;16:430. doi: 10.1186/s13063-015-0958-9.

26.

Interventions in randomised controlled trials in surgery: issues to consider during trial design.

Blencowe NS, Brown JM, Cook JA, Metcalfe C, Morton DG, Nicholl J, Sharples LD, Treweek S, Blazeby JM; Members of the MRC Hub for Trials Methodology Research Network Workshop.

Trials. 2015 Sep 4;16:392. doi: 10.1186/s13063-015-0918-4. Review.

27.

Perceptions of healthcare professionals and managers regarding the effectiveness of GP-led walk-in centres in the UK.

Arain M, Baxter S, Nicholl JP.

BMJ Open. 2015 Aug 21;5(8):e008286. doi: 10.1136/bmjopen-2015-008286.

28.

Variation in avoidable emergency admissions: multiple case studies of emergency and urgent care systems.

O'Cathain A, Knowles E, Turner J, Hirst E, Goodacre S, Nicholl J.

J Health Serv Res Policy. 2016 Jan;21(1):5-14. doi: 10.1177/1355819615596543. Epub 2015 Aug 5.

29.

Patient Experience in Single Rooms Compared with the Open Ward for Elective Orthopaedic Admissions.

Nahas S, Patel A, Duncan J, Nicholl J, Nathwani D.

Musculoskeletal Care. 2016 Mar;14(1):57-61. doi: 10.1002/msc.1110. Epub 2015 Jul 21. No abstract available.

PMID:
26197972
30.

Xp11.2 microduplications including IQSEC2, TSPYL2 and KDM5C genes in patients with neurodevelopmental disorders.

Moey C, Hinze SJ, Brueton L, Morton J, McMullan DJ, Kamien B, Barnett CP, Brunetti-Pierri N, Nicholl J, Gecz J, Shoubridge C.

Eur J Hum Genet. 2016 Mar;24(3):373-80. doi: 10.1038/ejhg.2015.123. Epub 2015 Jun 10.

31.

Acute ischaemic stroke patients - direct admission to a specialist centre or initial treatment in a local hospital? A systematic review.

Pickering A, Harnan S, Cooper K, Sutton A, Mason S, Nicholl J.

J Health Serv Res Policy. 2016 Jan;21(1):51-60. doi: 10.1177/1355819615586006. Epub 2015 May 19. Review.

PMID:
25990712
32.

Phenotypic variation of TTC19-deficient mitochondrial complex III deficiency: a case report and literature review.

Mordaunt DA, Jolley A, Balasubramaniam S, Thorburn DR, Mountford HS, Compton AG, Nicholl J, Manton N, Clark D, Bratkovic D, Friend K, Yu S.

Am J Med Genet A. 2015 Jun;167(6):1330-6. doi: 10.1002/ajmg.a.36968. Epub 2015 Apr 21. Review.

PMID:
25899669
33.

Explaining variation in emergency admissions: a mixed-methods study of emergency and urgent care systems.

O’Cathain A, Knowles E, Turner J, Maheswaran R, Goodacre S, Hirst E, Nicholl J.

Southampton (UK): NIHR Journals Library; 2014 Dec.

34.

Impact of prehospital transfer strategies in major trauma and head injury: systematic review, meta-analysis, and recommendations for study design.

Pickering A, Cooper K, Harnan S, Sutton A, Mason S, Nicholl J.

J Trauma Acute Care Surg. 2015 Jan;78(1):164-77. doi: 10.1097/TA.0000000000000483. Review.

35.

Phenotypes of AKT3 deletion: a case report and literature review.

Gai D, Haan E, Scholar M, Nicholl J, Yu S.

Am J Med Genet A. 2015 Jan;167A(1):174-9. doi: 10.1002/ajmg.a.36710. Epub 2014 Nov 25. Review.

PMID:
25424989
36.

Awareness and use of a new urgent care telephone service, NHS 111: cross-sectional population survey.

Knowles E, O'Cathain A, Turner J, Nicholl J.

J Health Serv Res Policy. 2014 Oct;19(4):224-30. doi: 10.1177/1355819614535571. Epub 2014 May 12.

PMID:
24819379
37.

An investigation of the impact of futility analysis in publicly funded trials.

Sully BG, Julious SA, Nicholl J.

Trials. 2014 Feb 17;15:61. doi: 10.1186/1745-6215-15-61.

38.

Effectiveness and cost-effectiveness of a telehealth intervention to support the management of long-term conditions: study protocol for two linked randomized controlled trials.

Thomas CL, Man MS, O'Cathain A, Hollinghurst S, Large S, Edwards L, Nicholl J, Montgomery AA, Salisbury C.

Trials. 2014 Jan 24;15:36. doi: 10.1186/1745-6215-15-36.

39.

Impact of a GP-led walk-in centre on NHS emergency departments.

Arain M, Campbell MJ, Nicholl JP.

Emerg Med J. 2015 Apr;32(4):295-300. doi: 10.1136/emermed-2013-202410. Epub 2014 Jan 9.

PMID:
24406328
40.

Interstitial deletion at chromosome 16p13.2 involving TMEM114 (transmembrane protein 114) in a boy and his father without cataract.

Gai D, Nicholl J, Waters W, Barnett CP, Yu S.

Am J Med Genet A. 2014 Mar;164A(3):834-6. doi: 10.1002/ajmg.a.36336. Epub 2013 Dec 19. No abstract available.

PMID:
24357539
41.

Acceptability of NHS 111 the telephone service for urgent health care: cross sectional postal survey of users' views.

O'Cathain A, Knowles E, Turner J, Nicholl J.

Fam Pract. 2014 Apr;31(2):193-200. doi: 10.1093/fampra/cmt078. Epub 2013 Dec 12.

42.

Cognitive deficit and autism spectrum disorders: prospective diagnosis by array CGH.

Nicholl J, Waters W, Mulley JC, Suwalski S, Brown S, Hull Y, Barnett C, Haan E, Thompson EM, Liebelt J, Mcgregor L, Harbord MG, Entwistle J, Munt C, White D, Chitti A, Baulderstone D, Ketteridge D; Array Referral Consortium, Friend K, Bain SM, Yu S.

Pathology. 2014 Jan;46(1):41-5. doi: 10.1097/PAT.0000000000000043.

PMID:
24300712
43.

Impact of the urgent care telephone service NHS 111 pilot sites: a controlled before and after study.

Turner J, O'Cathain A, Knowles E, Nicholl J.

BMJ Open. 2013 Nov 14;3(11):e003451. doi: 10.1136/bmjopen-2013-003451.

44.

Hospital characteristics affecting potentially avoidable emergency admissions: national ecological study.

O'Cathain A, Knowles E, Maheswaran R, Turner J, Hirst E, Goodacre S, Pearson T, Nicholl J.

Health Serv Manage Res. 2013 Nov;26(4):110-8. doi: 10.1177/0951484814525357. Epub 2014 Feb 27.

PMID:
25595008
45.

Direct risk standardisation: a new method for comparing casemix adjusted event rates using complex models.

Nicholl J, Jacques RM, Campbell MJ.

BMC Med Res Methodol. 2013 Oct 29;13:133. doi: 10.1186/1471-2288-13-133.

46.

Mortality indicators used to rank hospital performance.

Nicholl J, Jacques R, Campbell MJ.

BMJ. 2013 Oct 25;347:f5952. doi: 10.1136/bmj.f5952. No abstract available.

PMID:
24162939
47.

A system-wide approach to explaining variation in potentially avoidable emergency admissions: national ecological study.

O'Cathain A, Knowles E, Maheswaran R, Pearson T, Turner J, Hirst E, Goodacre S, Nicholl J.

BMJ Qual Saf. 2014 Jan;23(1):47-55. doi: 10.1136/bmjqs-2013-002003. Epub 2013 Jul 31.

48.

Return of the "corridors of shame"?

Nicholl J, Mason S.

BMJ. 2013 Jul 8;347:f4343. doi: 10.1136/bmj.f4343. No abstract available.

PMID:
23836617
49.

Did hospital mortality in England change from 2005 to 2010? A retrospective cohort analysis.

Jacques RM, Fotheringham J, Campbell MJ, Nicholl J.

BMC Health Serv Res. 2013 Jun 13;13:216. doi: 10.1186/1472-6963-13-216.

50.

A reinvestigation of recruitment to randomised, controlled, multicenter trials: a review of trials funded by two UK funding agencies.

Sully BG, Julious SA, Nicholl J.

Trials. 2013 Jun 9;14:166. doi: 10.1186/1745-6215-14-166. Review.

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