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Items: 1 to 50 of 201

1.

Potential early clinical stage colorectal cancer diagnosis using a proteomics blood test panel.

Ahn SB, Sharma S, Mohamedali A, Mahboob S, Redmond WJ, Pascovici D, Wu JX, Zaw T, Adhikari S, Vaibhav V, Nice EC, Baker MS.

Clin Proteomics. 2019 Aug 28;16:34. doi: 10.1186/s12014-019-9255-z. eCollection 2019.

2.

Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy.

Zhang Z, Gao W, Zhou L, Chen Y, Qin S, Zhang L, Liu J, He Y, Lei Y, Chen HN, Han J, Zhou ZG, Nice EC, Li C, Huang C, Wei X.

Theranostics. 2019 Jul 9;9(17):4878-4892. doi: 10.7150/thno.36254. eCollection 2019.

3.

MCT1 relieves osimertinib-induced CRC suppression by promoting autophagy through the LKB1/AMPK signaling.

Jin P, Jiang J, Xie N, Zhou L, Huang Z, Zhang L, Qin S, Fu S, Peng L, Gao W, Li B, Lei Y, Nice EC, Li C, Shao J, Xie K.

Cell Death Dis. 2019 Aug 13;10(8):615. doi: 10.1038/s41419-019-1844-2.

4.

Proteomics Reveals Cell-Surface Urokinase Plasminogen Activator Receptor Expression Impacts Most Hallmarks of Cancer.

Ahn SB, Mohamedali A, Pascovici D, Adhikari S, Sharma S, Nice EC, Baker MS.

Proteomics. 2019 Aug 11:e1900026. doi: 10.1002/pmic.201900026. [Epub ahead of print]

PMID:
31402590
5.

Oncoproteomics: Current status and future opportunities.

He Y, Mohamedali A, Huang C, Baker MS, Nice EC.

Clin Chim Acta. 2019 Aug;495:611-624. doi: 10.1016/j.cca.2019.06.006. Epub 2019 Jun 6. Review.

PMID:
31176645
6.

Molecular insights into cancer drug resistance from a proteomics perspective.

An Y, Zhou L, Huang Z, Nice EC, Zhang H, Huang C.

Expert Rev Proteomics. 2019 May;16(5):413-429. doi: 10.1080/14789450.2019.1601561. Epub 2019 Apr 12.

PMID:
30925852
7.

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma.

Jiang J, Zhang L, Chen H, Lei Y, Zhang T, Wang Y, Jin P, Lan J, Zhou L, Huang Z, Li B, Liu Y, Gao W, Xie K, Zhou L, Nice EC, Peng Y, Cao Y, Wei Y, Wang K, Huang C.

Autophagy. 2019 Mar 25:1-17. doi: 10.1080/15548627.2019.1598752. [Epub ahead of print]

PMID:
30909789
8.

Brefeldin A inhibits colorectal cancer growth by triggering Bip/Akt-regulated autophagy.

Zhou L, Gao W, Wang K, Huang Z, Zhang L, Zhang Z, Zhou J, Nice EC, Huang C.

FASEB J. 2019 Apr;33(4):5520-5534. doi: 10.1096/fj.201801983R. Epub 2019 Jan 22.

PMID:
30668917
9.

Tissue and plasma proteomics for early stage cancer detection.

Peng L, Cantor DI, Huang C, Wang K, Baker MS, Nice EC.

Mol Omics. 2018 Dec 3;14(6):405-423. doi: 10.1039/c8mo00126j. Review.

PMID:
30251724
10.

Proteomics and the microbiome: pitfalls and potential.

Lin H, He QY, Shi L, Sleeman M, Baker MS, Nice EC.

Expert Rev Proteomics. 2019 Jun;16(6):501-511. doi: 10.1080/14789450.2018.1523724. Epub 2018 Sep 28.

PMID:
30223687
11.

The cancer proteomic landscape and the HUPO Cancer Proteome Project.

Jimenez CR, Zhang H, Kinsinger CR, Nice EC.

Clin Proteomics. 2018 Jan 25;15:4. doi: 10.1186/s12014-018-9180-6. eCollection 2018.

12.

Pathology, proteomics and the pathway to personalised medicine.

Jin P, Lan J, Wang K, Baker MS, Huang C, Nice EC.

Expert Rev Proteomics. 2018 Mar;15(3):231-243. doi: 10.1080/14789450.2018.1425618. Epub 2018 Jan 16. Review.

PMID:
29310484
13.

Redox regulation in tumor cell epithelial-mesenchymal transition: molecular basis and therapeutic strategy.

Jiang J, Wang K, Chen Y, Chen H, Nice EC, Huang C.

Signal Transduct Target Ther. 2017 Aug 18;2:17036. doi: 10.1038/sigtrans.2017.36. eCollection 2017. Review.

14.

Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux.

Wang K, Zhang T, Lei Y, Li X, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Peng Y, Nice EC, Wu M, Huang C, Wei Y.

Autophagy. 2018;14(2):269-282. doi: 10.1080/15548627.2017.1409405. Epub 2018 Jan 29.

15.

Mining the fecal proteome: from biomarkers to personalised medicine.

Jin P, Wang K, Huang C, Nice EC.

Expert Rev Proteomics. 2017 May;14(5):445-459. doi: 10.1080/14789450.2017.1314786. Epub 2017 Apr 10. Review.

PMID:
28361558
16.

Proteogenomic studies on cancer drug resistance: towards biomarker discovery and target identification.

Fu S, Liu X, Luo M, Xie K, Nice EC, Zhang H, Huang C.

Expert Rev Proteomics. 2017 Apr;14(4):351-362. doi: 10.1080/14789450.2017.1299006. Epub 2017 Mar 6. Review.

PMID:
28276747
17.

Mass Spectrometry-Based Analysis for the Discovery and Validation of Potential Colorectal Cancer Stool Biomarkers.

Ang CS, Baker MS, Nice EC.

Methods Enzymol. 2017;586:247-274. doi: 10.1016/bs.mie.2016.10.019. Epub 2016 Dec 31.

PMID:
28137566
18.

Accelerating the search for the missing proteins in the human proteome.

Baker MS, Ahn SB, Mohamedali A, Islam MT, Cantor D, Verhaert PD, Fanayan S, Sharma S, Nice EC, Connor M, Ranganathan S.

Nat Commun. 2017 Jan 24;8:14271. doi: 10.1038/ncomms14271. Review. No abstract available.

19.

Redox proteomics screening cellular factors associated with oxidative stress in hepatocarcinogenesis.

Zhou L, Wen J, Huang Z, Nice EC, Huang C, Zhang H, Li Q.

Proteomics Clin Appl. 2017 Mar;11(3-4). doi: 10.1002/prca.201600089. Epub 2016 Dec 2. Review.

PMID:
27763721
20.

Proteomic profiling of human plasma for cancer biomarker discovery.

Huang Z, Ma L, Huang C, Li Q, Nice EC.

Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600240. Epub 2016 Oct 17. Review.

PMID:
27550791
21.

Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer.

Wang K, Gao W, Dou Q, Chen H, Li Q, Nice EC, Huang C.

Autophagy. 2016 Dec;12(12):2498-2499. Epub 2016 Sep 22.

22.

PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation.

Xie N, Yuan K, Zhou L, Wang K, Chen HN, Lei Y, Lan J, Pu Q, Gao W, Zhang L, Shen G, Li Q, Xiao H, Tang H, Xiang R, He M, Feng P, Nice EC, Wei Y, Zhang H, Yang J, Huang C.

Autophagy. 2016 Sep;12(9):1507-20. doi: 10.1080/15548627.2016.1191857. Epub 2016 Jun 15.

23.

Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer.

Dou Q, Chen HN, Wang K, Yuan K, Lei Y, Li K, Lan J, Chen Y, Huang Z, Xie N, Zhang L, Xiang R, Nice EC, Wei Y, Huang C.

Cancer Res. 2016 Aug 1;76(15):4457-69. doi: 10.1158/0008-5472.CAN-15-2887. Epub 2016 Jun 14.

24.

Nicotinamide phosphoribosyltransferase (Nampt) in carcinogenesis: new clinical opportunities.

Chen H, Wang S, Zhang H, Nice EC, Huang C.

Expert Rev Anticancer Ther. 2016 Aug;16(8):827-38. doi: 10.1080/14737140.2016.1190649. Epub 2016 Jul 5. Review.

PMID:
27186719
25.

Cancer drug resistance: redox resetting renders a way.

Liu Y, Li Q, Zhou L, Xie N, Nice EC, Zhang H, Huang C, Lei Y.

Oncotarget. 2016 Jul 5;7(27):42740-42761. doi: 10.18632/oncotarget.8600. Review.

26.

Clinical proteomics-driven precision medicine for targeted cancer therapy: current overview and future perspectives.

Zhou L, Wang K, Li Q, Nice EC, Zhang H, Huang C.

Expert Rev Proteomics. 2016;13(4):367-81. doi: 10.1586/14789450.2016.1159959. Epub 2016 Mar 16. Review.

PMID:
26923776
27.

From proteomics to personalized medicine: the road ahead.

Nice EC.

Expert Rev Proteomics. 2016;13(4):341-3. doi: 10.1586/14789450.2016.1158107. Epub 2016 Mar 17. No abstract available.

PMID:
26905403
28.

HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3.

Yuan K, Lei Y, Chen HN, Chen Y, Zhang T, Li K, Xie N, Wang K, Feng X, Pu Q, Yang W, Wu M, Xiang R, Nice EC, Wei Y, Huang C.

Cell Death Differ. 2016 Apr;23(4):616-27. doi: 10.1038/cdd.2015.129. Epub 2016 Jan 22.

29.

Stress management by autophagy: Implications for chemoresistance.

Huang Z, Zhou L, Chen Z, Nice EC, Huang C.

Int J Cancer. 2016 Jul 1;139(1):23-32. doi: 10.1002/ijc.29990. Epub 2016 Jan 28. Review.

30.

PDLIM1 Stabilizes the E-Cadherin/β-Catenin Complex to Prevent Epithelial-Mesenchymal Transition and Metastatic Potential of Colorectal Cancer Cells.

Chen HN, Yuan K, Xie N, Wang K, Huang Z, Chen Y, Dou Q, Wu M, Nice EC, Zhou ZG, Huang C.

Cancer Res. 2016 Mar 1;76(5):1122-34. doi: 10.1158/0008-5472.CAN-15-1962. Epub 2015 Dec 23.

31.

Oncoproteomics: Trials and tribulations.

Zhou L, Li Q, Wang J, Huang C, Nice EC.

Proteomics Clin Appl. 2016 Apr;10(4):516-31. doi: 10.1002/prca.201500081. Epub 2015 Dec 9. Review.

PMID:
26518147
32.

Redox signaling: Potential arbitrator of autophagy and apoptosis in therapeutic response.

Zhang L, Wang K, Lei Y, Li Q, Nice EC, Huang C.

Free Radic Biol Med. 2015 Dec;89:452-65. doi: 10.1016/j.freeradbiomed.2015.08.030. Epub 2015 Oct 9. Review.

PMID:
26454086
33.

Integrin αvβ6 sets the stage for colorectal cancer metastasis.

Cantor DI, Cheruku HR, Nice EC, Baker MS.

Cancer Metastasis Rev. 2015 Dec;34(4):715-34. doi: 10.1007/s10555-015-9591-z. Review.

PMID:
26337740
34.

High-throughput screening of cellular redox sensors using modern redox proteomics approaches.

Jiang J, Wang K, Nice EC, Zhang T, Huang C.

Expert Rev Proteomics. 2015;12(5):543-55. doi: 10.1586/14789450.2015.1069189. Epub 2015 Jul 16. Review.

PMID:
26184698
35.

Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.

Horvatovich P, Lundberg EK, Chen YJ, Sung TY, He F, Nice EC, Goode RJ, Yu S, Ranganathan S, Baker MS, Domont GB, Velasquez E, Li D, Liu S, Wang Q, He QY, Menon R, Guan Y, Corrales FJ, Segura V, Casal JI, Pascual-Montano A, Albar JP, Fuentes M, Gonzalez-Gonzalez M, Diez P, Ibarrola N, Degano RM, Mohammed Y, Borchers CH, Urbani A, Soggiu A, Yamamoto T, Salekdeh GH, Archakov A, Ponomarenko E, Lisitsa A, Lichti CF, Mostovenko E, Kroes RA, Rezeli M, Végvári Á, Fehniger TE, Bischoff R, Vizcaíno JA, Deutsch EW, Lane L, Nilsson CL, Marko-Varga G, Omenn GS, Jeong SK, Lim JS, Paik YK, Hancock WS.

J Proteome Res. 2015 Sep 4;14(9):3415-31. doi: 10.1021/pr5013009. Epub 2015 Jul 23.

36.

Recent findings from the Human Proteome Project: opening the mass spectrometry toolbox to advance cancer diagnosis, surveillance and treatment.

Cantor DI, Nice EC, Baker MS.

Expert Rev Proteomics. 2015 Jun;12(3):279-93. doi: 10.1586/14789450.2015.1040770. Epub 2015 Apr 30. Review.

PMID:
25925208
37.

CAPER 3.0: A Scalable Cloud-Based System for Data-Intensive Analysis of Chromosome-Centric Human Proteome Project Data Sets.

Yang S, Zhang X, Diao L, Guo F, Wang D, Liu Z, Li H, Zheng J, Pan J, Nice EC, Li D, He F.

J Proteome Res. 2015 Sep 4;14(9):3720-8. doi: 10.1021/pr501335w. Epub 2015 Mar 27.

PMID:
25794139
38.

New insights into redox regulation of stem cell self-renewal and differentiation.

Ren F, Wang K, Zhang T, Jiang J, Nice EC, Huang C.

Biochim Biophys Acta. 2015 Aug;1850(8):1518-26. doi: 10.1016/j.bbagen.2015.02.017. Epub 2015 Mar 10. Review.

PMID:
25766871
39.

Epithelial and stromal cell urokinase plasminogen activator receptor expression differentially correlates with survival in rectal cancer stages B and C patients.

Ahn SB, Chan C, Dent OF, Mohamedali A, Kwun SY, Clarke C, Fletcher J, Chapuis PH, Nice EC, Baker MS.

PLoS One. 2015 Feb 18;10(2):e0117786. doi: 10.1371/journal.pone.0117786. eCollection 2015.

40.

Interactomics: toward protein function and regulation.

Feng S, Zhou L, Huang C, Xie K, Nice EC.

Expert Rev Proteomics. 2015 Feb;12(1):37-60. doi: 10.1586/14789450.2015.1000870. Epub 2015 Jan 12. Review.

PMID:
25578092
41.

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1.

Liu R, Huang S, Lei Y, Zhang T, Wang K, Liu B, Nice EC, Xiang R, Xie K, Li J, Huang C.

Oncotarget. 2015 Jan 20;6(2):935-52.

42.

Characterization of the interaction between heterodimeric αvβ6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics.

Ahn SB, Mohamedali A, Anand S, Cheruku HR, Birch D, Sowmya G, Cantor D, Ranganathan S, Inglis DW, Frank R, Agrez M, Nice EC, Baker MS.

J Proteome Res. 2014 Dec 5;13(12):5956-64. doi: 10.1021/pr500849x. Epub 2014 Oct 29.

PMID:
25318615
43.

Thiol-based redox proteomics in cancer research.

Yuan K, Liu Y, Chen HN, Zhang L, Lan J, Gao W, Dou Q, Nice EC, Huang C.

Proteomics. 2015 Jan;15(2-3):287-99. doi: 10.1002/pmic.201400164. Epub 2014 Dec 15. Review.

PMID:
25251260
44.

Redox regulation of inflammation: old elements, a new story.

Lei Y, Wang K, Deng L, Chen Y, Nice EC, Huang C.

Med Res Rev. 2015 Mar;35(2):306-40. doi: 10.1002/med.21330. Epub 2014 Aug 29. Review.

PMID:
25171147
45.

Fibroblast growth factor receptors: multifactorial-contributors to tumor initiation and progression.

Feng S, Zhou L, Nice EC, Huang C.

Histol Histopathol. 2015 Jan;30(1):13-31. doi: 10.14670/HH-30.13. Epub 2014 Jul 23. Review.

PMID:
25053532
46.

Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

Liu R, Li J, Zhang T, Zou L, Chen Y, Wang K, Lei Y, Yuan K, Li Y, Lan J, Cheng L, Xie N, Xiang R, Nice EC, Huang C, Wei Y.

Autophagy. 2014 Jul;10(7):1241-55. doi: 10.4161/auto.28912. Epub 2014 May 15.

47.

ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid.

Zhang H, Lei Y, Yuan P, Li L, Luo C, Gao R, Tian J, Feng Z, Nice EC, Sun J.

PLoS One. 2014 May 8;9(5):e96418. doi: 10.1371/journal.pone.0096418. eCollection 2014.

48.

Recruitment of the adaptor protein Grb2 to EGFR tetramers.

Kozer N, Barua D, Henderson C, Nice EC, Burgess AW, Hlavacek WS, Clayton AH.

Biochemistry. 2014 Apr 29;53(16):2594-604. doi: 10.1021/bi500182x. Epub 2014 Apr 21.

49.

Proteomics, genomics and transcriptomics: their emerging roles in the discovery and validation of colorectal cancer biomarkers.

Wang K, Huang C, Nice EC.

Expert Rev Proteomics. 2014 Apr;11(2):179-205. doi: 10.1586/14789450.2014.894466. Epub 2014 Mar 10. Review.

PMID:
24611605
50.

Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB.

Chen Y, Liu J, Wu X, Nice EC.

Evid Based Complement Alternat Med. 2013;2013:309262. doi: 10.1155/2013/309262. Epub 2013 Dec 3.

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