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Items: 25

1.

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.

Hirota T, Blakeley P, Sangrithi MN, Mahadevaiah SK, Encheva V, Snijders AP, ElInati E, Ojarikre OA, de Rooij DG, Niakan KK, Turner JMA.

Dev Cell. 2018 Dec 3;47(5):645-659.e6. doi: 10.1016/j.devcel.2018.10.004. Epub 2018 Nov 1.

2.

Human Pre-gastrulation Development.

Wamaitha SE, Niakan KK.

Curr Top Dev Biol. 2018;128:295-338. doi: 10.1016/bs.ctdb.2017.11.004. Epub 2018 Feb 13. Review.

PMID:
29477167
3.

Erratum: Genome editing reveals a role for OCT4 in human embryogenesis.

Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, Bertero A, Turner JMA, Niakan KK.

Nature. 2017 Nov 9;551(7679):256. doi: 10.1038/nature24292. Epub 2017 Oct 4.

PMID:
28976971
4.

Genome editing reveals a role for OCT4 in human embryogenesis.

Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, Bertero A, Turner JMA, Niakan KK.

Nature. 2017 Oct 5;550(7674):67-73. doi: 10.1038/nature24033. Epub 2017 Sep 20. Erratum in: Nature. 2017 Oct 04;:.

5.

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.

Tomaz RA, Harman JL, Karimlou D, Weavers L, Fritsch L, Bou-Kheir T, Bell E, Del Valle Torres I, Niakan KK, Fisher C, Joshi O, Stunnenberg HG, Curry E, Ait-Si-Ali S, Jørgensen HF, Azuara V.

Development. 2017 Feb 15;144(4):567-579. doi: 10.1242/dev.142489. Epub 2017 Jan 13.

6.

Corrigendum: Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.

Hyslop LA, Blakeley P, Craven L, Richardson J, Fogarty NM, Fragouli E, Lamb M, Wamaitha SE, Prathalingam N, Zhang Q, O'Keefe H, Takeda Y, Arizzi L, Alfarawati S, Tuppen HA, Irving L, Kalleas D, Choudhary M, Wells D, Murdoch AP, Turnbull DM, Niakan KK, Herbert M.

Nature. 2016 Oct 27;538(7626):542. doi: 10.1038/nature19105. Epub 2016 Jul 27. No abstract available.

PMID:
27462813
7.

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.

Hyslop LA, Blakeley P, Craven L, Richardson J, Fogarty NM, Fragouli E, Lamb M, Wamaitha SE, Prathalingam N, Zhang Q, O'Keefe H, Takeda Y, Arizzi L, Alfarawati S, Tuppen HA, Irving L, Kalleas D, Choudhary M, Wells D, Murdoch AP, Turnbull DM, Niakan KK, Herbert M.

Nature. 2016 Jun 16;534(7607):383-6. doi: 10.1038/nature18303. Epub 2016 Jun 8. Erratum in: Nature. 2016 Oct 27;538(7626):542.

8.

Self-organization of the human embryo in the absence of maternal tissues.

Shahbazi MN, Jedrusik A, Vuoristo S, Recher G, Hupalowska A, Bolton V, Fogarty NNM, Campbell A, Devito L, Ilic D, Khalaf Y, Niakan KK, Fishel S, Zernicka-Goetz M.

Nat Cell Biol. 2016 Jun;18(6):700-708. doi: 10.1038/ncb3347. Epub 2016 May 4.

9.

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.

Blakeley P, Fogarty NM, Del Valle I, Wamaitha SE, Hu TX, Elder K, Snell P, Christie L, Robson P, Niakan KK.

Development. 2015 Oct 15;142(20):3613. doi: 10.1242/dev.131235.

10.

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.

Blakeley P, Fogarty NM, del Valle I, Wamaitha SE, Hu TX, Elder K, Snell P, Christie L, Robson P, Niakan KK.

Development. 2015 Sep 15;142(18):3151-65. doi: 10.1242/dev.123547. Epub 2015 Aug 20. Erratum in: Development. 2015 Oct 15;142(20):3613.

11.

Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells.

Wamaitha SE, del Valle I, Cho LT, Wei Y, Fogarty NM, Blakeley P, Sherwood RI, Ji H, Niakan KK.

Genes Dev. 2015 Jun 15;29(12):1239-55. doi: 10.1101/gad.257071.114.

12.

Dynamic Proteomic Profiling of Extra-Embryonic Endoderm Differentiation in Mouse Embryonic Stem Cells.

Mulvey CM, Schröter C, Gatto L, Dikicioglu D, Fidaner IB, Christoforou A, Deery MJ, Cho LT, Niakan KK, Martinez-Arias A, Lilley KS.

Stem Cells. 2015 Sep;33(9):2712-25. doi: 10.1002/stem.2067. Epub 2015 Jun 23.

13.

Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells.

Niakan KK, Schrode N, Cho LT, Hadjantonakis AK.

Nat Protoc. 2013 Jun;8(6):1028-41. doi: 10.1038/nprot.2013.049. Epub 2013 May 2.

14.

Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse.

Niakan KK, Eggan K.

Dev Biol. 2013 Mar 1;375(1):54-64. doi: 10.1016/j.ydbio.2012.12.008. Epub 2012 Dec 19.

15.

Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status.

Krueger C, King MR, Krueger F, Branco MR, Osborne CS, Niakan KK, Higgins MJ, Reik W.

PLoS One. 2012;7(7):e38983. doi: 10.1371/journal.pone.0038983. Epub 2012 Jul 3.

16.

Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states.

Cho LT, Wamaitha SE, Tsai IJ, Artus J, Sherwood RI, Pedersen RA, Hadjantonakis AK, Niakan KK.

Development. 2012 Aug;139(16):2866-77. doi: 10.1242/dev.078519. Epub 2012 Jul 12.

17.

Human pre-implantation embryo development.

Niakan KK, Han J, Pedersen RA, Simon C, Pera RA.

Development. 2012 Mar;139(5):829-41. doi: 10.1242/dev.060426. Review.

18.

BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.

Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger M, Smith JC, Bardwell L, Moffett A, Pedersen RA.

Cell Stem Cell. 2011 Aug 5;9(2):144-55. doi: 10.1016/j.stem.2011.06.015.

19.

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.

Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K.

Genes Dev. 2010 Feb 1;24(3):312-26. doi: 10.1101/gad.1833510.

20.

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons.

Dimos JT, Rodolfa KT, Niakan KK, Weisenthal LM, Mitsumoto H, Chung W, Croft GF, Saphier G, Leibel R, Goland R, Wichterle H, Henderson CE, Eggan K.

Science. 2008 Aug 29;321(5893):1218-21. doi: 10.1126/science.1158799. Epub 2008 Jul 31.

21.

Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis.

Niakan KK, Davis EC, Clipsham RC, Jiang M, Dehart DB, Sulik KK, McCabe ER.

Mol Genet Metab. 2006 Jul;88(3):261-71. Epub 2006 Feb 8.

PMID:
16466956
22.

DAX1 origin, function, and novel role.

Niakan KK, McCabe ER.

Mol Genet Metab. 2005 Sep-Oct;86(1-2):70-83. Review.

PMID:
16146703
23.

IL1RAPL1 is associated with mental retardation in patients with complex glycerol kinase deficiency who have deletions extending telomeric of DAX1.

Zhang YH, Huang BL, Niakan KK, McCabe LL, McCabe ER, Dipple KM.

Hum Mutat. 2004 Sep;24(3):273.

PMID:
15300857
24.

X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction.

Yu C, Niakan KK, Matsushita M, Stamatoyannopoulos G, Orkin SH, Raskind WH.

Blood. 2002 Sep 15;100(6):2040-5.

25.

Mapping of a syndrome of X-linked thrombocytopenia with Thalassemia to band Xp11-12: further evidence of genetic heterogeneity of X-linked thrombocytopenia.

Raskind WH, Niakan KK, Wolff J, Matsushita M, Vaughan T, Stamatoyannopoulos G, Watanabe C, Rios J, Ochs HD.

Blood. 2000 Apr 1;95(7):2262-8.

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