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Brief Report: Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients with RET-Rearranged Lung Cancers.

Drilon A, Lin JJ, Filleron T, Ni A, Milia J, Bergagnini I, Hatzoglou V, Velcheti V, Offin M, Li B, Carbone DP, Besse B, Mok T, Awad MM, Wolf J, Owen D, Camidge DR, Riely GJ, Peled N, Kris MG, Mazieres J, Gainor JF, Gautschi O.

J Thorac Oncol. 2018 Jul 11. pii: S1556-0864(18)30780-9. doi: 10.1016/j.jtho.2018.07.004. [Epub ahead of print]


Safety and Efficacy of Retreating with Immunotherapy After Immune-Related Adverse Events in Patients with NSCLC.

Santini FC, Rizvi H, Plodkowski AJ, Ni A, Lacouture ME, Gambarin-Gelwan M, Wilkins O, Panora E, Halpenny DF, Long NM, Kris MG, Rudin CM, Chaft JE, Hellmann MD.

Cancer Immunol Res. 2018 Jul 10. pii: canimm.0755.2017. doi: 10.1158/2326-6066.CIR-17-0755. [Epub ahead of print]


Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial.

Li BT, Shen R, Buonocore D, Olah ZT, Ni A, Ginsberg MS, Ulaner GA, Offin M, Feldman D, Hembrough T, Cecchi F, Schwartz S, Pavlakis N, Clarke S, Won HH, Brzostowski EB, Riely GJ, Solit DB, Hyman DM, Drilon A, Rudin CM, Berger MF, Baselga J, Scaltriti M, Arcila ME, Kris MG.

J Clin Oncol. 2018 Jul 10:JCO2018779777. doi: 10.1200/JCO.2018.77.9777. [Epub ahead of print]


Outcomes of Relapsed and Refractory Primary Mediastinal (Thymic) Large B Cell Lymphoma Treated with Second-Line Therapy and Intent to Transplant.

Vardhana S, Hamlin PA, Yang J, Zelenetz A, Sauter CS, Matasar MJ, Ni A, Yahalom J, Moskowitz CH.

Biol Blood Marrow Transplant. 2018 Jun 15. pii: S1083-8791(18)30321-5. doi: 10.1016/j.bbmt.2018.06.009. [Epub ahead of print]


Toward a panoramic perspective of the association between environmental factors and cardiovascular disease: An environment-wide association study from National Health and Nutrition Examination Survey 1999-2014.

Zhuang X, Guo Y, Ni A, Yang D, Liao L, Zhang S, Zhou H, Sun X, Wang L, Wang X, Liao X.

Environ Int. 2018 Sep;118:146-153. doi: 10.1016/j.envint.2018.05.046. Epub 2018 Jun 4.


Cognition as a Window into Neuronal Population Space.

Ruff DA, Ni AM, Cohen MR.

Annu Rev Neurosci. 2018 Jul 8;41:77-97. doi: 10.1146/annurev-neuro-080317-061936.


The neural signatures of egocentric bias in normative decision-making.

Feng C, Feng X, Wang L, Wang L, Gu R, Ni A, Deshpande G, Li Z, Luo YJ.

Brain Imaging Behav. 2018 May 16. doi: 10.1007/s11682-018-9893-1. [Epub ahead of print]


Ketamine exposure demographics and outcomes over 16 years as reported to US poison centers.

Ni A, Lee Cantrell F, Clark RF.

Am J Emerg Med. 2018 May 3. pii: S0735-6757(18)30361-9. doi: 10.1016/j.ajem.2018.04.066. [Epub ahead of print]


Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Hellmann MD, Nathanson T, Rizvi H, Creelan BC, Sanchez-Vega F, Ahuja A, Ni A, Novik JB, Mangarin LMB, Abu-Akeel M, Liu C, Sauter JL, Rekhtman N, Chang E, Callahan MK, Chaft JE, Voss MH, Tenet M, Li XM, Covello K, Renninger A, Vitazka P, Geese WJ, Borghaei H, Rudin CM, Antonia SJ, Swanton C, Hammerbacher J, Merghoub T, McGranahan N, Snyder A, Wolchok JD.

Cancer Cell. 2018 May 14;33(5):843-852.e4. doi: 10.1016/j.ccell.2018.03.018. Epub 2018 Apr 12.


Genome-wide detection of CNVs associated with beak deformity in chickens using high-density 600K SNP arrays.

Bai H, Sun Y, Liu N, Liu Y, Xue F, Li Y, Xu S, Ni A, Ye J, Chen Y, Chen J.

Anim Genet. 2018 Jun;49(3):226-236. doi: 10.1111/age.12652. Epub 2018 Apr 11.


An organic-inorganic hybrid zinc phosphite framework with room temperature phosphorescence.

Ni AY, Mu Y, Pan J, Han SD, Shang MM, Wang GM.

Chem Commun (Camb). 2018 Apr 10;54(30):3712-3714. doi: 10.1039/c8cc00724a.


Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance.

Yu HA, Suzawa K, Jordan E, Zehir A, Ni A, Kim R, Kris MG, Hellmann MD, Li BT, Somwar R, Solit DB, Berger MF, Arcila M, Riely GJ, Ladanyi M.

Clin Cancer Res. 2018 Jul 1;24(13):3108-3118. doi: 10.1158/1078-0432.CCR-17-2961. Epub 2018 Mar 12.


The second conserved motif in bacterial laccase regulates catalysis and robustness.

Jin L, Yang X, Sheng Y, Cao H, Ni A, Zhang Y.

Appl Microbiol Biotechnol. 2018 May;102(9):4039-4048. doi: 10.1007/s00253-018-8863-2. Epub 2018 Mar 7.


Anti-Epstein-Barr virus antibodies in Beijing during 2013-2017: What we have found in the different patients.

Cui J, Yan W, Xu S, Wang Q, Zhang W, Liu W, Ni A.

PLoS One. 2018 Mar 1;13(3):e0193171. doi: 10.1371/journal.pone.0193171. eCollection 2018.


Learning and attention reveal a general relationship between population activity and behavior.

Ni AM, Ruff DA, Alberts JJ, Symmonds J, Cohen MR.

Science. 2018 Jan 26;359(6374):463-465. doi: 10.1126/science.aao0284.


Environment-wide association study to identify novel factors associated with peripheral arterial disease: Evidence from the National Health and Nutrition Examination Survey (1999-2004).

Zhuang X, Ni A, Liao L, Guo Y, Dai W, Jiang Y, Zhou H, Hu X, Du Z, Wang X, Liao X.

Atherosclerosis. 2018 Feb;269:172-177. doi: 10.1016/j.atherosclerosis.2018.01.006. Epub 2018 Jan 12.


Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.

Rizvi H, Sanchez-Vega F, La K, Chatila W, Jonsson P, Halpenny D, Plodkowski A, Long N, Sauter JL, Rekhtman N, Hollmann T, Schalper KA, Gainor JF, Shen R, Ni A, Arbour KC, Merghoub T, Wolchok J, Snyder A, Chaft JE, Kris MG, Rudin CM, Socci ND, Berger MF, Taylor BS, Zehir A, Solit DB, Arcila ME, Ladanyi M, Riely GJ, Schultz N, Hellmann MD.

J Clin Oncol. 2018 Mar 1;36(7):633-641. doi: 10.1200/JCO.2017.75.3384. Epub 2018 Jan 16.


The Effects of a Macromolecular Charring Agent with Gas Phase and Condense Phase Synergistic Flame Retardant Capability on the Properties of PP/IFR Composites.

Chen H, Wang J, Ni A, Ding A, Han X, Sun Z.

Materials (Basel). 2018 Jan 11;11(1). pii: E111. doi: 10.3390/ma11010111.


Alteration of glucocorticoid receptors and exacerbation of inflammation during lytic cytomegalovirus infection in THP-1 cells.

Wang S, Dou Y, Yang H, Ni A, Zhang R, Qian J.

FEBS Open Bio. 2017 Oct 30;7(12):1924-1931. doi: 10.1002/2211-5463.12334. eCollection 2017 Dec.


Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer.

Arbour KC, Jordan E, Kim HR, Dienstag J, Yu HA, Sanchez-Vega F, Lito P, Berger M, Solit DB, Hellmann M, Kris MG, Rudin CM, Ni A, Arcila M, Ladanyi M, Riely GJ.

Clin Cancer Res. 2018 Jan 15;24(2):334-340. doi: 10.1158/1078-0432.CCR-17-1841. Epub 2017 Oct 31.


Novel histone deacetylase inhibitor N25 exerts anti-tumor effects and induces autophagy in human glioma cells by inhibiting HDAC3.

Sun XY, Qu Y, Ni AR, Wang GX, Huang WB, Chen ZP, Lv ZF, Zhang S, Lindsay H, Zhao S, Li XN, Feng BH.

Oncotarget. 2017 Sep 8;8(43):75232-75242. doi: 10.18632/oncotarget.20744. eCollection 2017 Sep 26.


Twice weekly pulse and daily continuous-dose erlotinib as initial treatment for patients with epidermal growth factor receptor-mutant lung cancers and brain metastases.

Arbour KC, Kris MG, Riely GJ, Ni A, Beal K, Daras M, Hayes SA, Young RJ, Rodriguez CR, Ahn L, Pao W, Yu HA.

Cancer. 2018 Jan 1;124(1):105-109. doi: 10.1002/cncr.30990. Epub 2017 Sep 21.


Prognostic significance of baseline metabolic tumor volume in relapsed and refractory Hodgkin lymphoma.

Moskowitz AJ, Schöder H, Gavane S, Thoren KL, Fleisher M, Yahalom J, McCall SJ, Cadzin BR, Fox SY, Gerecitano J, Grewal R, Hamlin PA, Horwitz SM, Kumar A, Matasar M, Ni A, Noy A, Palomba ML, Perales MA, Portlock CS, Sauter C, Straus D, Younes A, Zelenetz AD, Moskowitz CH.

Blood. 2017 Nov 16;130(20):2196-2203. doi: 10.1182/blood-2017-06-788877. Epub 2017 Sep 5.


Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors.

Arbour KC, Naidoo J, Steele KE, Ni A, Moreira AL, Rekhtman N, Robbins PB, Karakunnel J, Rimner A, Huang J, Riely GJ, Hellmann MD.

PLoS One. 2017 Aug 3;12(8):e0182665. doi: 10.1371/journal.pone.0182665. eCollection 2017.


A regularized variable selection procedure in additive hazards model with stratified case-cohort design.

Ni A, Cai J.

Lifetime Data Anal. 2018 Jul;24(3):443-463. doi: 10.1007/s10985-017-9402-7. Epub 2017 Jul 28.


Spatially tuned normalization explains attention modulation variance within neurons.

Ni AM, Maunsell JHR.

J Neurophysiol. 2017 Sep 1;118(3):1903-1913. doi: 10.1152/jn.00218.2017. Epub 2017 Jul 12.


Prognostic impact of TTF-1 expression in patients with stage IV lung adenocarcinomas.

Schilsky JB, Ni A, Ahn L, Datta S, Travis WD, Kris MG, Chaft JE, Rekhtman N, Hellmann MD.

Lung Cancer. 2017 Jun;108:205-211. doi: 10.1016/j.lungcan.2017.03.015. Epub 2017 Mar 28.


Spirometry Reference Equations from the HCHS/SOL (Hispanic Community Health Study/Study of Latinos).

LaVange L, Davis SM, Hankinson J, Enright P, Wilson R, Barr RG, Aldrich TK, Kalhan R, Lemus H, Ni A, Smith LJ, Talavera GA.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):993-1003. doi: 10.1164/rccm.201610-1987OC.


Variable selection for case-cohort studies with failure time outcome.

Ni AI, Cai J, Zeng D.

Biometrika. 2016 Sep;103(3):547-562. doi: 10.1093/biomet/asw027. Epub 2016 Aug 10.


Association of Visual Acuity with Ocular Dominance in 2045 Myopic Patients.

Zhou D, Ni N, Ni A, Chen Q, Hu DN, Zhou J.

Curr Eye Res. 2017 Aug;42(8):1155-1159. doi: 10.1080/02713683.2017.1297464. Epub 2017 May 11.


Expression of the inhibitory receptor NKG2A correlates with increased liver and splenic NK cell response to activating receptor engagement.

Meyer CE, Key PN, Zhu T, Shabsovich M, Ni A, Tripathy SK.

Immun Inflamm Dis. 2017 Jun;5(2):177-189. doi: 10.1002/iid3.156. Epub 2017 Mar 24.


The time course of morphological processing during spoken word recognition in Chinese.

Shen W, Qu Q, Ni A, Zhou J, Li X.

Psychon Bull Rev. 2017 Dec;24(6):1957-1963. doi: 10.3758/s13423-017-1274-z.


Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.

Jordan EJ, Kim HR, Arcila ME, Barron D, Chakravarty D, Gao J, Chang MT, Ni A, Kundra R, Jonsson P, Jayakumaran G, Gao SP, Johnsen HC, Hanrahan AJ, Zehir A, Rekhtman N, Ginsberg MS, Li BT, Yu HA, Paik PK, Drilon A, Hellmann MD, Reales DN, Benayed R, Rusch VW, Kris MG, Chaft JE, Baselga J, Taylor BS, Schultz N, Rudin CM, Hyman DM, Berger MF, Solit DB, Ladanyi M, Riely GJ.

Cancer Discov. 2017 Jun;7(6):596-609. doi: 10.1158/2159-8290.CD-16-1337. Epub 2017 Mar 23.


Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

Gardner EE, Lok BH, Schneeberger VE, Desmeules P, Miles LA, Arnold PK, Ni A, Khodos I, de Stanchina E, Nguyen T, Sage J, Campbell JE, Ribich S, Rekhtman N, Dowlati A, Massion PP, Rudin CM, Poirier JT.

Cancer Cell. 2017 Feb 13;31(2):286-299. doi: 10.1016/j.ccell.2017.01.006.


Antibody-mediated thyroid dysfunction during T-cell checkpoint blockade in patients with non-small-cell lung cancer.

Osorio JC, Ni A, Chaft JE, Pollina R, Kasler MK, Stephens D, Rodriguez C, Cambridge L, Rizvi H, Wolchok JD, Merghoub T, Rudin CM, Fish S, Hellmann MD.

Ann Oncol. 2017 Mar 1;28(3):583-589. doi: 10.1093/annonc/mdw640.


Oncolytic Adenovirus Complexes Coated with Lipids and Calcium Phosphate for Cancer Gene Therapy.

Chen J, Gao P, Yuan S, Li R, Ni A, Chu L, Ding L, Sun Y, Liu XY, Duan Y.

ACS Nano. 2016 Dec 27;10(12):11548-11560. doi: 10.1021/acsnano.6b06182. Epub 2016 Dec 15.


SNORD126 promotes HCC and CRC cell growth by activating the PI3K-AKT pathway through FGFR2.

Fang X, Yang D, Luo H, Wu S, Dong W, Xiao J, Yuan S, Ni A, Zhang KJ, Liu XY, Chu L.

J Mol Cell Biol. 2017 Jun 1;9(3):243-255. doi: 10.1093/jmcb/mjw048.


The relative contribution of the medial and lateral femoral circumflex arteries to the vascularity of the head and neck of the femur: a quantitative MRI-based assessment.

Dewar DC, Lazaro LE, Klinger CE, Sculco PK, Dyke JP, Ni AY, Helfet DL, Lorich DG.

Bone Joint J. 2016 Dec;98-B(12):1582-1588.


Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial.

Drilon A, Rekhtman N, Arcila M, Wang L, Ni A, Albano M, Van Voorthuysen M, Somwar R, Smith RS, Montecalvo J, Plodkowski A, Ginsberg MS, Riely GJ, Rudin CM, Ladanyi M, Kris MG.

Lancet Oncol. 2016 Dec;17(12):1653-1660. doi: 10.1016/S1470-2045(16)30562-9. Epub 2016 Nov 4.


Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.

Xin J, You D, Breslin P, Li J, Zhang J, Wei W, Cannova J, Volk A, Gutierrez R, Xiao Y, Ni A, Ng G, Schmidt R, Xia Z, Pan J, Chen H, Patel MM, Kuo PC, Nand S, Kini AR, Zhang J, Chen J, Zhu J, Zhang J.

Leukemia. 2017 May;31(5):1154-1165. doi: 10.1038/leu.2016.287. Epub 2016 Oct 17.


Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice.

Xin J, Breslin P, Wei W, Li J, Gutierrez R, Cannova J, Ni A, Ng G, Schmidt R, Chen H, Parini V, Kuo PC, Kini AR, Stiff P, Zhu J, Zhang J.

Haematologica. 2017 Feb;102(2):295-307. doi: 10.3324/haematol.2016.151514. Epub 2016 Sep 15.


A phase II study of axitinib (AG-013736) in patients with incurable adenoid cystic carcinoma.

Ho AL, Dunn L, Sherman EJ, Fury MG, Baxi SS, Chandramohan R, Dogan S, Morris LG, Cullen GD, Haque S, Sima CS, Ni A, Antonescu CR, Katabi N, Pfister DG.

Ann Oncol. 2016 Oct;27(10):1902-8. doi: 10.1093/annonc/mdw287. Epub 2016 Aug 26.


An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells.

Yuan S, Fang X, Xu Y, Ni A, Liu XY, Chu L.

Oncotarget. 2016 Sep 13;7(37):60491-60502. doi: 10.18632/oncotarget.11134.


PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.

Lok BH, Gardner EE, Schneeberger VE, Ni A, Desmeules P, Rekhtman N, de Stanchina E, Teicher BA, Riaz N, Powell SN, Poirier JT, Rudin CM.

Clin Cancer Res. 2017 Jan 15;23(2):523-535. doi: 10.1158/1078-0432.CCR-16-1040. Epub 2016 Jul 20.


Th17 Cell Response in SOD1G93A Mice following Motor Nerve Injury.

Ni A, Yang T, Mesnard-Hoaglin NA, Gutierrez R, Stubbs EB Jr, McGuire SO, Sanders VM, Jones KJ, Foecking EM, Xin J.

Mediators Inflamm. 2016;2016:6131234. doi: 10.1155/2016/6131234. Epub 2016 Apr 18.


Strategies for targeting primate neural circuits with viral vectors.

El-Shamayleh Y, Ni AM, Horwitz GD.

J Neurophysiol. 2016 Jul 1;116(1):122-34. doi: 10.1152/jn.00087.2016. Epub 2016 Apr 6. Review.


Assessing the Feasibility of a Web-Based Weight Loss Intervention for Low-Income Women of Reproductive Age: A Pilot Study.

Cavallo DN, Sisneros JA, Ronay AA, Robbins CL, Jilcott Pitts SB, Keyserling TC, Ni A, Morrow J, Vu MB, Johnston LF, Samuel-Hodge CD.

JMIR Res Protoc. 2016 Feb 26;5(1):e30. doi: 10.2196/resprot.4865.


Parity and Components of the Metabolic Syndrome Among US Hispanic/Latina Women: Results From the Hispanic Community Health Study/Study of Latinos.

Vladutiu CJ, Siega-Riz AM, Sotres-Alvarez D, Stuebe AM, Ni A, Tabb KM, Gallo LC, Potter JE, Heiss G.

Circ Cardiovasc Qual Outcomes. 2016 Feb;9(2 Suppl 1):S62-9. doi: 10.1161/CIRCOUTCOMES.115.002464.


Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.

Schrader KA, Cheng DT, Joseph V, Prasad M, Walsh M, Zehir A, Ni A, Thomas T, Benayed R, Ashraf A, Lincoln A, Arcila M, Stadler Z, Solit D, Hyman DM, Zhang L, Klimstra D, Ladanyi M, Offit K, Berger M, Robson M.

JAMA Oncol. 2016 Jan;2(1):104-11. doi: 10.1001/jamaoncol.2015.5208. Erratum in: JAMA Oncol. 2016 Feb;2(2):279. Hyman, David [corrected to Hyman, David M].


Tetracycline-Containing MCM-41 Mesoporous Silica Nanoparticles for the Treatment of Escherichia coli.

Koneru B, Shi Y, Wang YC, Chavala SH, Miller ML, Holbert B, Conson M, Ni A, Di Pasqua AJ.

Molecules. 2015 Oct 30;20(11):19690-8. doi: 10.3390/molecules201119650.

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