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Items: 15

1.

SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor.

Liu S, Nheu T, Luwor R, Nicholson SE, Zhu HJ.

J Biol Chem. 2015 Jul 17;290(29):17894-908. doi: 10.1074/jbc.M114.607184. Epub 2015 Jun 1.

2.

Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity.

Luwor RB, Hakmana D, Iaria J, Nheu TV, Simpson RJ, Zhu HJ.

Mol Cancer. 2015 Feb 22;14:50. doi: 10.1186/s12943-015-0309-1.

3.

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo.

Luwor RB, Baradaran B, Taylor LE, Iaria J, Nheu TV, Amiry N, Hovens CM, Wang B, Kaye AH, Zhu HJ.

Oncogene. 2013 May 9;32(19):2433-41. doi: 10.1038/onc.2012.260. Epub 2012 Jul 2.

4.

New reagents for improved in vitro and in vivo examination of TGF-β signalling.

Luwor RB, Wang B, Nheu TV, Iaria J, Tsantikos E, Hibbs ML, Sieber OM, Zhu HJ.

Growth Factors. 2011 Oct;29(5):211-8. doi: 10.3109/08977194.2011.615311.

PMID:
21913800
5.

Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice.

Hirokawa Y, Nheu T, Grimm K, Mautner V, Maeda S, Yoshida M, Komiyama K, Maruta H.

Cancer Biol Ther. 2006 Mar;5(3):305-9. Epub 2006 Mar 12.

PMID:
16418572
6.

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P, Inglese M, McLoughlin RM, Jones SA, Topley N, Baumann H, Judd LM, Giraud AS, Boussioutas A, Zhu HJ, Ernst M.

Nat Med. 2005 Aug;11(8):845-52. Epub 2005 Jul 24.

PMID:
16041381
7.

PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition.

Nheu T, He H, Hirokawa Y, Walker F, Wood J, Maruta H.

Cell Cycle. 2004 Jan;3(1):71-4.

PMID:
14657670
8.

Rho family-associated kinases PAK1 and rock.

Maruta H, Nheu TV, He H, Hirokawa Y.

Prog Cell Cycle Res. 2003;5:203-10. Review.

PMID:
14593714
9.

The K252a derivatives, inhibitors for the PAK/MLK kinase family selectively block the growth of RAS transformants.

Nheu TV, He H, Hirokawa Y, Tamaki K, Florin L, Schmitz ML, Suzuki-Takahashi I, Jorissen RN, Burgess AW, Nishimura S, Wood J, Maruta H.

Cancer J. 2002 Jul-Aug;8(4):328-36.

PMID:
12184411
10.

Interfering with Ras signaling using membrane-permeable peptides or drugs.

Maruta H, He H, Nheu T.

Methods Mol Biol. 2002;189:75-85. No abstract available.

PMID:
12094596
11.

CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase.

Zaffran Y, Destaing O, Roux A, Ory S, Nheu T, Jurdic P, Rabourdin-Combe C, Astier AL.

J Immunol. 2001 Dec 15;167(12):6780-5.

12.

Efficient syntheses of novel C2'-alkylated (+/-)-K252a analogues.

Tamaki K, Shotwell JB, White RD, Drutu I, Petsch DT, Nheu TV, He H, Hirokawa Y, Maruta H, Wood JL.

Org Lett. 2001 May 31;3(11):1689-92.

PMID:
11405687
13.

Design of inhibitors of Ras--Raf interaction using a computational combinatorial algorithm.

Zeng J, Nheu T, Zorzet A, Catimel B, Nice E, Maruta H, Burgess AW, Treutlein HR.

Protein Eng. 2001 Jan;14(1):39-45.

PMID:
11287677
14.

Drad21, a Drosophila rad21 homologue expressed in S-phase cells.

Warren WD, Lin E, Nheu TV, Hime GR, McKay MJ.

Gene. 2000 May 30;250(1-2):77-84.

PMID:
10854781
15.

Mitochondrial FtsZ in a chromophyte alga.

Beech PL, Nheu T, Schultz T, Herbert S, Lithgow T, Gilson PR, McFadden GI.

Science. 2000 Feb 18;287(5456):1276-9.

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