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Items: 11

1.

A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum.

Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, Llinás M, Pradel G.

PLoS Pathog. 2018 Aug 22;14(8):e1007249. doi: 10.1371/journal.ppat.1007249. eCollection 2018 Aug.

2.

Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum.

Ngwa CJ, Kiesow MJ, Papst O, Orchard LM, Filarsky M, Rosinski AN, Voss TS, Llinás M, Pradel G.

Front Cell Infect Microbiol. 2017 Jul 24;7:320. doi: 10.3389/fcimb.2017.00320. eCollection 2017.

3.

Ivermectin treatment of Loa loa hyper-microfilaraemic baboons (Papio anubis): Assessment of microfilarial load reduction, haematological and biochemical parameters and histopathological changes following treatment.

Wanji S, Eyong EJ, Tendongfor N, Ngwa CJ, Esuka EN, Kengne-Ouafo AJ, Datchoua-Poutcheu FR, Enyong P, Agnew D, Eversole RR, Hopkins A, Mackenzie CD.

PLoS Negl Trop Dis. 2017 Jul 7;11(7):e0005576. doi: 10.1371/journal.pntd.0005576. eCollection 2017 Jul.

4.

Pyrethroids and DDT tolerance of Anopheles gambiae s.l. from Sengerema District, an area of intensive pesticide usage in north-western Tanzania.

Philbert A, Lyantagaye SL, Pradel G, Ngwa CJ, Nkwengulila G.

Trop Med Int Health. 2017 Apr;22(4):388-398. doi: 10.1111/tmi.12850. Epub 2017 Mar 9.

5.

Bistacrine derivatives as new potent antimalarials.

Schmidt I, Pradel G, Sologub L, Golzmann A, Ngwa CJ, Kucharski A, Schirmeister T, Holzgrabe U.

Bioorg Med Chem. 2016 Aug 15;24(16):3636-42. doi: 10.1016/j.bmc.2016.06.003. Epub 2016 Jun 4.

PMID:
27316542
6.

The Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement.

Rosa TF, Flammersfeld A, Ngwa CJ, Kiesow M, Fischer R, Zipfel PF, Skerka C, Pradel G.

Cell Microbiol. 2016 Apr;18(4):573-90. doi: 10.1111/cmi.12535. Epub 2015 Nov 12.

7.

Coming soon: probiotics-based malaria vaccines.

Ngwa CJ, Pradel G.

Trends Parasitol. 2015 Jan;31(1):2-4. doi: 10.1016/j.pt.2014.11.006. Epub 2014 Dec 18.

PMID:
25532754
8.

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

Trenholme K, Marek L, Duffy S, Pradel G, Fisher G, Hansen FK, Skinner-Adams TS, Butterworth A, Ngwa CJ, Moecking J, Goodman CD, McFadden GI, Sumanadasa SD, Fairlie DP, Avery VM, Kurz T, Andrews KT.

Antimicrob Agents Chemother. 2014 Jul;58(7):3666-78. doi: 10.1128/AAC.02721-13. Epub 2014 Apr 14.

9.

Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito.

Ngwa CJ, Scheuermayer M, Mair GR, Kern S, Brügl T, Wirth CC, Aminake MN, Wiesner J, Fischer R, Vilcinskas A, Pradel G.

BMC Genomics. 2013 Apr 15;14:256. doi: 10.1186/1471-2164-14-256.

11.

Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity.

Röhrich CR, Ngwa CJ, Wiesner J, Schmidtberg H, Degenkolb T, Kollewe C, Fischer R, Pradel G, Vilcinskas A.

Biol Lett. 2012 Apr 23;8(2):308-11. doi: 10.1098/rsbl.2011.0760. Epub 2011 Sep 21.

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