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Items: 38


BioBits Health: Classroom Activities Exploring Engineering, Biology, and Human Health with Fluorescent Readouts.

Stark JC, Huang A, Hsu KJ, Dubner RS, Forbrook J, Marshalla S, Rodriguez F, Washington M, Rybnicky GA, Nguyen PQ, Hasselbacher B, Jabri R, Kamran R, Koralewski V, Wightkin W, Martinez T, Jewett MC.

ACS Synth Biol. 2019 May 17;8(5):1001-1009. doi: 10.1021/acssynbio.8b00381. Epub 2019 May 7.


Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus.

Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, Ahmed R, Treanor JJ, Martinez-Sobrido L, Golding H, Khurana S, Zand MS, Topham DJ, Sangster MY.

J Virol. 2019 Apr 3;93(8). pii: e00169-19. doi: 10.1128/JVI.00169-19. Print 2019 Apr 15.


Bootstrapped Biocatalysis: Biofilm-Derived Materials as Reversibly Functionalizable Multienzyme Surfaces.

Nussbaumer MG, Nguyen PQ, Tay PKR, Naydich A, Hysi E, Botyanszki Z, Joshi NS.

ChemCatChem. 2017 Dec 8;9(23):4328-4333. doi: 10.1002/cctc.201701221. Epub 2017 Aug 2.


BioBits™ Bright: A fluorescent synthetic biology education kit.

Stark JC, Huang A, Nguyen PQ, Dubner RS, Hsu KJ, Ferrante TC, Anderson M, Kanapskyte A, Mucha Q, Packett JS, Patel P, Patel R, Qaq D, Zondor T, Burke J, Martinez T, Miller-Berry A, Puppala A, Reichert K, Schmid M, Brand L, Hill LR, Chellaswamy JF, Faheem N, Fetherling S, Gong E, Gonzalzles EM, Granito T, Koritsaris J, Nguyen B, Ottman S, Palffy C, Patel A, Skweres S, Slaton A, Woods T, Donghia N, Pardee K, Collins JJ, Jewett MC.

Sci Adv. 2018 Aug 1;4(8):eaat5107. doi: 10.1126/sciadv.aat5107. eCollection 2018 Aug.


BioBits™ Explorer: A modular synthetic biology education kit.

Huang A, Nguyen PQ, Stark JC, Takahashi MK, Donghia N, Ferrante T, Dy AJ, Hsu KJ, Dubner RS, Pardee K, Jewett MC, Collins JJ.

Sci Adv. 2018 Aug 1;4(8):eaat5105. doi: 10.1126/sciadv.aat5105. eCollection 2018 Aug.


PPARγ regulates meibocyte differentiation and lipid synthesis of cultured human meibomian gland epithelial cells (hMGEC).

Kim SW, Xie Y, Nguyen PQ, Bui VT, Huynh K, Kang JS, Brown DJ, Jester JV.

Ocul Surf. 2018 Oct;16(4):463-469. doi: 10.1016/j.jtos.2018.07.004. Epub 2018 Jul 7.


Tracking of Engineered Bacteria In Vivo Using Nonstandard Amino Acid Incorporation.

Praveschotinunt P, Dorval Courchesne NM, den Hartog I, Lu C, Kim JJ, Nguyen PQ, Joshi NS.

ACS Synth Biol. 2018 Jun 15;7(6):1640-1650. doi: 10.1021/acssynbio.8b00135. Epub 2018 Jun 6.


Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression.

Cho H, Rambout X, Gleghorn ML, Nguyen PQT, Phipps CR, Miyoshi K, Myers JR, Kataoka N, Fasan R, Maquat LE.

Genes Dev. 2018 Apr 1;32(7-8):555-567. doi: 10.1101/gad.309773.117. Epub 2018 Apr 13.


Human periodontal ligament cells exhibit no endotoxin tolerance upon stimulation with Porphyromonas gingivalis lipopolysaccharide.

Blufstein A, Behm C, Nguyen PQ, Rausch-Fan X, Andrukhov O.

J Periodontal Res. 2018 Aug;53(4):589-597. doi: 10.1111/jre.12549. Epub 2018 Mar 26.


Engineered Living Materials: Prospects and Challenges for Using Biological Systems to Direct the Assembly of Smart Materials.

Nguyen PQ, Courchesne ND, Duraj-Thatte A, Praveschotinunt P, Joshi NS.

Adv Mater. 2018 May;30(19):e1704847. doi: 10.1002/adma.201704847. Epub 2018 Feb 12. Review.


A Synthetic Circuit for Mercury Bioremediation Using Self-Assembling Functional Amyloids.

Tay PKR, Nguyen PQ, Joshi NS.

ACS Synth Biol. 2017 Oct 20;6(10):1841-1850. doi: 10.1021/acssynbio.7b00137. Epub 2017 Aug 2.


Synthetic biology engineering of biofilms as nanomaterials factories.

Nguyen PQ.

Biochem Soc Trans. 2017 Jun 15;45(3):585-597. doi: 10.1042/BST20160348. Review.


Portable, On-Demand Biomolecular Manufacturing.

Pardee K, Slomovic S, Nguyen PQ, Lee JW, Donghia N, Burrill D, Ferrante T, McSorley FR, Furuta Y, Vernet A, Lewandowski M, Boddy CN, Joshi NS, Collins JJ.

Cell. 2016 Sep 22;167(1):248-259.e12. doi: 10.1016/j.cell.2016.09.013.


Immunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea).

Nguyen KN, Nguyen GK, Nguyen PQ, Ang KH, Dedon PC, Tam JP.

FEBS J. 2016 Jun;283(11):2067-90. doi: 10.1111/febs.13720. Epub 2016 Apr 20.


Streptomyces thermoautotrophicus does not fix nitrogen.

MacKellar D, Lieber L, Norman JS, Bolger A, Tobin C, Murray JW, Oksaksin M, Chang RL, Ford TJ, Nguyen PQ, Woodward J, Permingeat HR, Joshi NS, Silver PA, Usadel B, Rutherford AW, Friesen ML, Prell J.

Sci Rep. 2016 Feb 1;6:20086. doi: 10.1038/srep20086.


Cysteine-Rich Peptide Family with Unusual Disulfide Connectivity from Jasminum sambac.

Kumari G, Serra A, Shin J, Nguyen PQ, Sze SK, Yoon HS, Tam JP.

J Nat Prod. 2015 Nov 25;78(11):2791-9. doi: 10.1021/acs.jnatprod.5b00762. Epub 2015 Nov 10.


Antiviral Cystine Knot α-Amylase Inhibitors from Alstonia scholaris.

Nguyen PQ, Ooi JS, Nguyen NT, Wang S, Huang M, Liu DX, Tam JP.

J Biol Chem. 2015 Dec 25;290(52):31138-50. doi: 10.1074/jbc.M115.654855. Epub 2015 Nov 6.


Studies on the Chitin Binding Property of Novel Cysteine-Rich Peptides from Alternanthera sessilis.

Kini SG, Nguyen PQ, Weissbach S, Mallagaray A, Shin J, Yoon HS, Tam JP.

Biochemistry. 2015 Nov 3;54(43):6639-49. doi: 10.1021/acs.biochem.5b00872. Epub 2015 Oct 21.


Engineered catalytic biofilms: Site-specific enzyme immobilization onto E. coli curli nanofibers.

Botyanszki Z, Tay PK, Nguyen PQ, Nussbaumer MG, Joshi NS.

Biotechnol Bioeng. 2015 Oct;112(10):2016-24. doi: 10.1002/bit.25638. Epub 2015 May 20.


Allotides: Proline-Rich Cystine Knot α-Amylase Inhibitors from Allamanda cathartica.

Nguyen PQ, Luu TT, Bai Y, Nguyen GK, Pervushin K, Tam JP.

J Nat Prod. 2015 Apr 24;78(4):695-704. doi: 10.1021/np500866c. Epub 2015 Apr 2.


Programmable biofilm-based materials from engineered curli nanofibres.

Nguyen PQ, Botyanszki Z, Tay PK, Joshi NS.

Nat Commun. 2014 Sep 17;5:4945. doi: 10.1038/ncomms5945.


Discovery and characterization of pseudocyclic cystine-knot α-amylase inhibitors with high resistance to heat and proteolytic degradation.

Nguyen PQ, Wang S, Kumar A, Yap LJ, Luu TT, Lescar J, Tam JP.

FEBS J. 2014 Oct;281(19):4351-66. doi: 10.1111/febs.12939. Epub 2014 Aug 8.


Patterned surface with controllable wettability for inkjet printing of flexible printed electronics.

Nguyen PQ, Yeo LP, Lok BK, Lam YC.

ACS Appl Mater Interfaces. 2014 Mar 26;6(6):4011-6. doi: 10.1021/am4054546. Epub 2014 Mar 12.


Mechanical reinforcement of polymeric fibers through peptide nanotube incorporation.

Rubin DJ, Nia HT, Desire T, Nguyen PQ, Gevelber M, Ortiz C, Joshi NS.

Biomacromolecules. 2013 Oct 14;14(10):3370-5. doi: 10.1021/bm4008293. Epub 2013 Oct 3.


Discovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants.

Nguyen GK, Lian Y, Pang EW, Nguyen PQ, Tran TD, Tam JP.

J Biol Chem. 2013 Feb 1;288(5):3370-80. doi: 10.1074/jbc.M112.415356. Epub 2012 Nov 29.


Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities.

Nguyen GK, Lim WH, Nguyen PQ, Tam JP.

J Biol Chem. 2012 May 18;287(21):17598-607. doi: 10.1074/jbc.M111.338970. Epub 2012 Mar 30.


Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity.

Judd J, Wei F, Nguyen PQ, Tartaglia LJ, Agbandje-McKenna M, Silberg JJ, Suh J.

Mol Ther Nucleic Acids. 2012 Nov 13;1:e54. doi: 10.1038/mtna.2012.46.


Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family.

Nguyen GK, Zhang S, Nguyen NT, Nguyen PQ, Chiu MS, Hardjojo A, Tam JP.

J Biol Chem. 2011 Jul 8;286(27):24275-87. doi: 10.1074/jbc.M111.229922. Epub 2011 May 19.


Mesophilic and hyperthermophilic adenylate kinases differ in their tolerance to random fragmentation.

Segall-Shapiro TH, Nguyen PQ, Dos Santos ED, Subedi S, Judd J, Suh J, Silberg JJ.

J Mol Biol. 2011 Feb 11;406(1):135-48. doi: 10.1016/j.jmb.2010.11.057. Epub 2010 Dec 8.


Serum cytokine levels in periodontitis patients in relation to the bacterial load.

Andrukhov O, Ulm C, Reischl H, Nguyen PQ, Matejka M, Rausch-Fan X.

J Periodontol. 2011 Jun;82(6):885-92. doi: 10.1902/jop.2010.100425. Epub 2010 Dec 7.


Computational design of chimeric protein libraries for directed evolution.

Silberg JJ, Nguyen PQ, Stevenson T.

Methods Mol Biol. 2010;673:175-88. doi: 10.1007/978-1-60761-842-3_10.


A selection that reports on protein-protein interactions within a thermophilic bacterium.

Nguyen PQ, Silberg JJ.

Protein Eng Des Sel. 2010 Jul;23(7):529-36. doi: 10.1093/protein/gzq024. Epub 2010 Apr 23.


In vivo fluorescent detection of Fe-S clusters coordinated by human GRX2.

Hoff KG, Culler SJ, Nguyen PQ, McGuire RM, Silberg JJ, Smolke CD.

Chem Biol. 2009 Dec 24;16(12):1299-308. doi: 10.1016/j.chembiol.2009.11.011.


Thermostability promotes the cooperative function of split adenylate kinases.

Nguyen PQ, Liu S, Thompson JC, Silberg JJ.

Protein Eng Des Sel. 2008 May;21(5):303-10. doi: 10.1093/protein/gzn005. Epub 2008 Feb 20.


Degradation of oxidized proteins by autophagy during oxidative stress in Arabidopsis.

Xiong Y, Contento AL, Nguyen PQ, Bassham DC.

Plant Physiol. 2007 Jan;143(1):291-9. Epub 2006 Nov 10.


Simplified discodermolide analogues: synthesis and biological evaluation of 4-epi-7-dehydroxy-14,16-didemethyl-(+)-discodermolides as microtubule-stabilizing agents.

Choy N, Shin Y, Nguyen PQ, Curran DP, Balachandran R, Madiraju C, Day BW.

J Med Chem. 2003 Jul 3;46(14):2846-64.


Enantioselective oxidative coupling of the titanium enolate of 3-phenylacetyl-2-oxazolidinone.

Nguyen PQ, Schäfer HJ.

Org Lett. 2001 Sep 20;3(19):2993-5.


Increased risk of neisserial infections in systemic lupus erythematosus.

Mitchell SR, Nguyen PQ, Katz P.

Semin Arthritis Rheum. 1990 Dec;20(3):174-84. Review.


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