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Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections.

Ji Y, Dang X, Nguyen LNT, Nguyen LN, Zhao J, Cao D, Khanal S, Schank M, Wu XY, Morrison ZD, Zou Y, El Gazzar M, Ning S, Wang L, Moorman JP, Yao ZQ.

Immun Ageing. 2019 Jun 24;16:12. doi: 10.1186/s12979-019-0153-z. eCollection 2019.

Free PMC Article

Novel promoters derived from Chinese Hamster Ovary cells via in silico and in vitro analysis.

Nguyen LN, Baumann M, Dhiman H, Marx N, Schmieder V, Hussein M, Eisenhut P, Hernandez I, Koehn J, Borth N.

Biotechnol J. 2019 Jul 4:e1900125. doi: 10.1002/biot.201900125. [Epub ahead of print]


Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions.

Cao D, Zhao J, Nguyan LN, Nguyen LNT, Khanal S, Dang X, Schank M, Chand Thakuri BK, Wu XY, Morrison ZD, Ei Gazzar M, Zou Y, Ning S, Wang L, Moorman JP, Yao ZQ.

Front Immunol. 2019 May 22;10:1152. doi: 10.3389/fimmu.2019.01152. eCollection 2019.


Application of rumen and anaerobic sludge microbes for bio harvesting from lignocellulosic biomass.

Nguyen LN, Nguyen AQ, Johir MAH, Guo W, Ngo HH, Chaves AV, Nghiem LD.

Chemosphere. 2019 Aug;228:702-708. doi: 10.1016/j.chemosphere.2019.04.159. Epub 2019 Apr 29.


Prognosis value of Serum Cytokine levels among burn-induced ards patients.

Nguyen LN, Tran DH, Dong KH.

Ann Burns Fire Disasters. 2018 Sep 30;31(3):185-188.


Antiseptic chlorhexidine in activated sludge: Biosorption, antimicrobial susceptibility, and alteration of community structure.

Keerthisinghe TP, Nguyen LN, Kwon EE, Oh S.

J Environ Manage. 2019 May 1;237:629-635. doi: 10.1016/j.jenvman.2019.02.043. Epub 2019 Mar 6.


CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1.

Yi G, Mandoli A, Jussen L, Tijchon E, van Bergen MGJM, Cordonnier G, Hansen M, Kim B, Nguyen LN, Jansen PWTC, Vermeulen M, van der Reijden B, van den Akker E, Bond J, Martens JHA.

Blood Cancer J. 2019 Mar 8;9(3):33. doi: 10.1038/s41408-019-0194-8.


Impacts of mixing on foaming, methane production, stratification and microbial community in full-scale anaerobic co-digestion process.

Nguyen LN, Johir MAH, Commault A, Bustamante H, Aurisch R, Lowrie R, Nghiem LD.

Bioresour Technol. 2019 Jun;281:226-233. doi: 10.1016/j.biortech.2019.02.077. Epub 2019 Feb 19.


Cometabolic biotransformation and impacts of the anti-inflammatory drug diclofenac on activated sludge microbial communities.

Nguyen LN, Nghiem LD, Pramanik BK, Oh S.

Sci Total Environ. 2019 Mar 20;657:739-745. doi: 10.1016/j.scitotenv.2018.12.094. Epub 2018 Dec 7.


Pelvic Floor Distress Inventory Scores Improve After Prolapse Surgery Regardless of Surgical Approach but Not After Observation Alone.

Han E, Nguyen LN, Gilleran J, Bartley J, Killinger KA, Boura JA, Sirls LT.

Urology. 2019 Feb;124:62-71. doi: 10.1016/j.urology.2018.10.040. Epub 2018 Nov 1.


Recovery of urinary function after robotic-assisted laparoscopic prostatectomy versus radical perineal prostatectomy for early-stage prostate cancer.

Jafri SM, Nguyen LN, Sirls LT.

Int Urol Nephrol. 2018 Dec;50(12):2187-2191. doi: 10.1007/s11255-018-2013-8. Epub 2018 Oct 16.


Evaluation of cell-surface displayed synthetic consensus dengue EDIII cells as a potent oral vaccine candidate.

Bal J, Jung HY, Nguyen LN, Park J, Jang YS, Kim DH.

Microb Cell Fact. 2018 Sep 14;17(1):146. doi: 10.1186/s12934-018-0994-8.


HCV-associated exosomes promote myeloid-derived suppressor cell expansion via inhibiting miR-124 to regulate T follicular cell differentiation and function.

Wang L, Cao D, Wang L, Zhao J, Nguyen LN, Dang X, Ji Y, Wu XY, Morrison ZD, Xie Q, El Gazzar M, Ning S, Moorman JP, Yao ZQ.

Cell Discov. 2018 Sep 11;4:51. doi: 10.1038/s41421-018-0052-z. eCollection 2018.


Inhibition of TRF2 accelerates telomere attrition and DNA damage in naïve CD4 T cells during HCV infection.

Nguyen LN, Zhao J, Cao D, Dang X, Wang L, Lian J, Zhang Y, Jia Z, Wu XY, Morrison Z, Xie Q, Ji Y, Zhang Z, El Gazzar M, Ning S, Moorman JP, Yao ZQ.

Cell Death Dis. 2018 Sep 5;9(9):900. doi: 10.1038/s41419-018-0897-y.


Gallium indium eutectic masking prior to porous silicon formation creates unique spatially-dependent chemistries.

Collado CM, Horner IJ, Empey JM, Nguyen LNQ, Bright FV.

Anal Chim Acta. 2018 Nov 22;1032:147-153. doi: 10.1016/j.aca.2018.05.052. Epub 2018 May 19.


Aerobic biotransformation of the antibiotic ciprofloxacin by Bradyrhizobium sp. isolated from activated sludge.

Nguyen LN, Nghiem LD, Oh S.

Chemosphere. 2018 Nov;211:600-607. doi: 10.1016/j.chemosphere.2018.08.004. Epub 2018 Aug 2.


The signalling roles of sphingosine-1-phosphate derived from red blood cells and platelets.

Tukijan F, Chandrakanthan M, Nguyen LN.

Br J Pharmacol. 2018 Oct;175(19):3741-3746. doi: 10.1111/bph.14451. Epub 2018 Aug 31. Review.


Dynamic CTC phenotypes in metastatic prostate cancer models visualized using magnetic ranking cytometry.

Kermanshah L, Poudineh M, Ahmed S, Nguyen LNM, Srikant S, Makonnen R, Pena Cantu F, Corrigan M, Kelley SO.

Lab Chip. 2018 Jul 10;18(14):2055-2064. doi: 10.1039/c8lc00310f.


5-Aminolevulinic Acid-Induced Fluorescence in Focal Cortical Dysplasia: Report of 3 Cases.

Roberts DW, Bravo JJ, Olson JD, Hickey WF, Harris BT, Nguyen LN, Hong J, Evans LT, Fan X, Wirth D, Wilson BC, Paulsen KD.

Oper Neurosurg (Hagerstown). 2019 Apr 1;16(4):403-414. doi: 10.1093/ons/opy116.


A single amino acid substitution in the NS4B protein of Dengue virus confers enhanced virus growth and fitness in human cells in vitro through IFN-dependent host response.

Bui TT, Moi ML, Nabeshima T, Takemura T, Nguyen TT, Nguyen LN, Pham HTT, Nguyen TTT, Manh DH, Dumre SP, Mizukami S, Hirayama K, Tajima S, Le MTQ, Aoyagi K, Hasebe F, Morita K.

J Gen Virol. 2018 Aug;99(8):1044-1057. doi: 10.1099/jgv.0.001092. Epub 2018 Jun 19.


Electrodeposited Amorphous Tungsten-doped Cobalt Oxide as an Efficient Catalyst for the Oxygen Evolution Reaction.

Nguyen LN, Thuy UTD, Truong QD, Honma I, Nguyen QL, Tran PD.

Chem Asian J. 2018 Jun 18;13(12):1530-1534. doi: 10.1002/asia.201800401. Epub 2018 May 29.


Insufficiency of DNA repair enzyme ATM promotes naive CD4 T-cell loss in chronic hepatitis C virus infection.

Zhao J, Dang X, Zhang P, Nguyen LN, Cao D, Wang L, Wu X, Morrison ZD, Zhang Y, Jia Z, Xie Q, Wang L, Ning S, El Gazzar M, Moorman JP, Yao ZQ.

Cell Discov. 2018 Apr 10;4:16. doi: 10.1038/s41421-018-0015-4. eCollection 2018.


Additional treatments, satisfaction, symptoms and quality of life in women 1 year after vaginal and abdominal pelvic organ prolapse repair.

Nguyen LN, Gruner M, Killinger KA, Peters KM, Boura JA, Jankowski M, Sirls LT.

Int Urol Nephrol. 2018 Jun;50(6):1031-1037. doi: 10.1007/s11255-018-1846-5. Epub 2018 Mar 16.


Does sex matter? A matched pairs analysis of neuromodulation outcomes in women and men.

Nguyen LN, Bartley J, Killinger KA, Gupta P, Lavin J, Khourdaji A, Gilleran J, Gaines N, Boura JA, Peters KM.

Int Urol Nephrol. 2018 May;50(5):825-832. doi: 10.1007/s11255-018-1843-8. Epub 2018 Mar 13.


Dried Blood Spots, an Affordable Tool to Collect, Ship, and Sequence gDNA from Patients with an X-Linked Agammaglobulinemia Phenotype Residing in a Developing Country.

Segundo GRS, Nguyen ATV, Thuc HT, Nguyen LNQ, Kobayashi RH, Le HT, Le HTM, Torgerson TR, Ochs HD.

Front Immunol. 2018 Feb 16;9:289. doi: 10.3389/fimmu.2018.00289. eCollection 2018.


Preterm birth with placental evidence of malperfusion is associated with cardiovascular risk factors after pregnancy: a prospective cohort study.

Catov JM, Muldoon MF, Reis SE, Ness RB, Nguyen LN, Yamal JM, Hwang H, Parks WT.

BJOG. 2018 Jul;125(8):1009-1017. doi: 10.1111/1471-0528.15040. Epub 2017 Dec 28.


Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia.

Almiron Bonnin DA, Havrda MC, Lee MC, Liu H, Zhang Z, Nguyen LN, Harrington LX, Hassanpour S, Cheng C, Israel MA.

Oncogene. 2018 Feb 22;37(8):1107-1118. doi: 10.1038/onc.2017.404. Epub 2017 Nov 20.


Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets.

Vu TM, Ishizu AN, Foo JC, Toh XR, Zhang F, Whee DM, Torta F, Cazenave-Gassiot A, Matsumura T, Kim S, Toh SES, Suda T, Silver DL, Wenk MR, Nguyen LN.

Nature. 2017 Oct 26;550(7677):524-528. doi: 10.1038/nature24053. Epub 2017 Oct 18.


Continuous transformation of chiral pharmaceuticals in enzymatic membrane bioreactors for advanced wastewater treatment.

Nguyen LN, Hai FI, McDonald JA, Khan SJ, Price WE, Nghiem LD.

Water Sci Technol. 2017 Oct;76(7-8):1816-1826. doi: 10.2166/wst.2017.331.


Preparing our next generation of pathologists: The criticality of critical reading.

Nguyen LN, Parks WT.

Cancer Cytopathol. 2018 Feb;126(2):81-82. doi: 10.1002/cncy.21920. Epub 2017 Sep 20. No abstract available.


Probing the solvation structure and dynamics in ionic liquids by time-resolved infrared spectroscopy of 4-(dimethylamino)benzonitrile.

Ando RA, Brown-Xu SE, Nguyen LNQ, Gustafson TL.

Phys Chem Chem Phys. 2017 Sep 20;19(36):25151-25157. doi: 10.1039/c7cp04961g.


Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity.

van Eijl RAPM, van den Brand T, Nguyen LN, Mulder KW.

Sci Rep. 2017 Aug 4;7(1):7278. doi: 10.1038/s41598-017-07539-4.


Maternal Antiviral Immunoglobulin Accumulates in Neural Tissue of Neonates To Prevent HSV Neurological Disease.

Jiang Y, Patel CD, Manivanh R, North B, Backes IM, Posner DA, Gilli F, Pachner AR, Nguyen LN, Leib DA.

MBio. 2017 Jul 5;8(4). pii: e00678-17. doi: 10.1128/mBio.00678-17.


The Risks and Benefits of Cavernous Neurovascular Bundle Sparing during Radical Prostatectomy: A Systematic Review and Meta-Analysis.

Nguyen LN, Head L, Witiuk K, Punjani N, Mallick R, Cnossen S, Fergusson DA, Cagiannos I, Lavallée LT, Morash C, Breau RH.

J Urol. 2017 Oct;198(4):760-769. doi: 10.1016/j.juro.2017.02.3344. Epub 2017 Mar 9.


The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.

Liu NQ, Ter Huurne M, Nguyen LN, Peng T, Wang SY, Studd JB, Joshi O, Ongen H, Bramsen JB, Yan J, Andersen CL, Taipale J, Dermitzakis ET, Houlston RS, Hubner NC, Stunnenberg HG.

Nat Commun. 2017 Feb 14;8:14418. doi: 10.1038/ncomms14418.


Warfarin use and the risk of mortality, stroke, and bleeding in hemodialysis patients with atrial fibrillation.

Kai B, Bogorad Y, Nguyen LN, Yang SJ, Chen W, Spencer HT, Shen AY, Lee MS.

Heart Rhythm. 2017 May;14(5):645-651. doi: 10.1016/j.hrthm.2017.01.047. Epub 2017 Feb 6.


Profiling Functional and Biochemical Phenotypes of Circulating Tumor Cells Using a Two-Dimensional Sorting Device.

Poudineh M, Labib M, Ahmed S, Nguyen LN, Kermanshah L, Mohamadi RM, Sargent EH, Kelley SO.

Angew Chem Int Ed Engl. 2017 Jan 2;56(1):163-168. doi: 10.1002/anie.201608983. Epub 2016 Nov 29.


Prostate volume estimations using magnetic resonance imaging and transrectal ultrasound compared to radical prostatectomy specimens.

Paterson NR, Lavallée LT, Nguyen LN, Witiuk K, Ross J, Mallick R, Shabana W, MacDonald B, Scheida N, Fergusson D, Momoli F, Cnossen S, Morash C, Cagiannos I, Breau RH.

Can Urol Assoc J. 2016 Aug;10(7-8):264-268.


The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.

Mandoli A, Singh AA, Prange KHM, Tijchon E, Oerlemans M, Dirks R, Ter Huurne M, Wierenga ATJ, Janssen-Megens EM, Berentsen K, Sharifi N, Kim B, Matarese F, Nguyen LN, Hubner NC, Rao NA, van den Akker E, Altucci L, Vellenga E, Stunnenberg HG, Martens JHA.

Cell Rep. 2016 Nov 15;17(8):2087-2100. doi: 10.1016/j.celrep.2016.08.082.


BODIPY-Conjugated Xyloside Primes Fluorescent Glycosaminoglycans in the Inner Ear of Opsanus tau.

Holman HA, Tran VM, Kalita M, Nguyen LN, Arungundram S, Kuberan B, Rabbitt RD.

J Assoc Res Otolaryngol. 2016 Dec;17(6):525-540. Epub 2016 Sep 12.


Bilateral Pulmonary Agenesis: A Rare and Unexpected Finding in a Newborn.

Nguyen LN, Parks WT.

AJP Rep. 2016 Apr;6(2):e246-9. doi: 10.1055/s-0036-1584530.


Hepatitis C Virus Nonstructural 5A Protein Interacts with Abelson Interactor 1 and Modulates Epidermal Growth Factor-mediated MEK/ERK Signaling Pathway.

Huynh VT, Lim YS, Tran SC, Pham TM, Nguyen LN, Hwang SB.

J Biol Chem. 2016 Oct 21;291(43):22607-22617. Epub 2016 Aug 22.


Nonstructural 3 Protein of Hepatitis C Virus Modulates the Tribbles Homolog 3/Akt Signaling Pathway for Persistent Viral Infection.

Tran SC, Pham TM, Nguyen LN, Park EM, Lim YS, Hwang SB.

J Virol. 2016 Jul 27;90(16):7231-7247. doi: 10.1128/JVI.00326-16. Print 2016 Aug 15.


Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.

Wong BH, Chan JP, Cazenave-Gassiot A, Poh RW, Foo JC, Galam DL, Ghosh S, Nguyen LN, Barathi VA, Yeo SW, Luu CD, Wenk MR, Silver DL.

J Biol Chem. 2016 May 13;291(20):10501-14. doi: 10.1074/jbc.M116.721340. Epub 2016 Mar 22.


Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A.

Quek DQ, Nguyen LN, Fan H, Silver DL.

J Biol Chem. 2016 Apr 29;291(18):9383-94. doi: 10.1074/jbc.M116.721035. Epub 2016 Mar 4.


Rhizobium radiobacter: A Recently Recognized Cause of Bacterial Keratitis.

Barker NH, Thompson JM, Mullen MG, Weekes MA, Nguyen LN, Haynes CK, Miller D.

Cornea. 2016 May;35(5):679-82. doi: 10.1097/ICO.0000000000000780.


Continuous adsorption and biotransformation of micropollutants by granular activated carbon-bound laccase in a packed-bed enzyme reactor.

Nguyen LN, Hai FI, Dosseto A, Richardson C, Price WE, Nghiem LD.

Bioresour Technol. 2016 Jun;210:108-16. doi: 10.1016/j.biortech.2016.01.014. Epub 2016 Jan 11.


Laccase-syringaldehyde-mediated degradation of trace organic contaminants in an enzymatic membrane reactor: Removal efficiency and effluent toxicity.

Nguyen LN, van de Merwe JP, Hai FI, Leusch FD, Kang J, Price WE, Roddick F, Magram SF, Nghiem LD.

Bioresour Technol. 2016 Jan;200:477-84. doi: 10.1016/j.biortech.2015.10.054. Epub 2015 Oct 19.


Methamphetamine Alters the Antimicrobial Efficacy of Phagocytic Cells during Methicillin-Resistant Staphylococcus aureus Skin Infection.

Mihu MR, Roman-Sosa J, Varshney AK, Eugenin EA, Shah BP, Ham Lee H, Nguyen LN, Guimaraes AJ, Fries BC, Nosanchuk JD, Martinez LR.

MBio. 2015 Oct 27;6(6):e01622-15. doi: 10.1128/mBio.01622-15.


BEND3 is involved in the human-specific repression of calreticulin: Implication for the evolution of higher brain functions in human.

Aghajanirefah A, Nguyen LN, Ohadi M.

Gene. 2016 Jan 15;576(1 Pt 3):577-80. doi: 10.1016/j.gene.2015.10.040. Epub 2015 Oct 19.


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