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Items: 8


Expression of the SNAI2 transcriptional repressor is regulated by C16-ceramide.

Lu P, White-Gilbertson S, Nganga R, Kester M, Voelkel-Johnson C.

Cancer Biol Ther. 2019;20(6):922-930. doi: 10.1080/15384047.2019.1579962. Epub 2019 Mar 5.


Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis.

Nganga R, Oleinik N, Kim J, Selvam SP, De Palma R, Johnson KA, Parikh RY, Gangaraju V, Peterson Y, Dany M, Stahelin RV, Voelkel-Johnson C, Szulc ZM, Bieberich E, Ogretmen B.

J Biol Chem. 2019 Jan 11;294(2):502-519. doi: 10.1074/jbc.RA118.005865. Epub 2018 Nov 12.


Mechanisms of Ceramide-Dependent Cancer Cell Death.

Nganga R, Oleinik N, Ogretmen B.

Adv Cancer Res. 2018;140:1-25. doi: 10.1016/bs.acr.2018.04.007.


Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.

Panneer Selvam S, Roth BM, Nganga R, Kim J, Cooley MA, Helke K, Smith CD, Ogretmen B.

J Biol Chem. 2018 Jun 22;293(25):9784-9800. doi: 10.1074/jbc.RA118.003506. Epub 2018 May 10.


TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis.

Gencer S, Oleinik N, Kim J, Panneer Selvam S, De Palma R, Dany M, Nganga R, Thomas RJ, Senkal CE, Howe PH, Ogretmen B.

Sci Signal. 2017 Oct 24;10(502). pii: eaam7464. doi: 10.1126/scisignal.aam7464.


HPV/E7 induces chemotherapy-mediated tumor suppression by ceramide-dependent mitophagy.

Thomas RJ, Oleinik N, Panneer Selvam S, Vaena SG, Dany M, Nganga RN, Depalma R, Baron KD, Kim J, Szulc ZM, Ogretmen B.

EMBO Mol Med. 2017 Aug;9(8):1030-1051. doi: 10.15252/emmm.201607088.


Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML.

Dany M, Gencer S, Nganga R, Thomas RJ, Oleinik N, Baron KD, Szulc ZM, Ruvolo P, Kornblau S, Andreeff M, Ogretmen B.

Blood. 2016 Oct 13;128(15):1944-1958. Epub 2016 Aug 18.


Advances in immunotherapy for melanoma management.

Dany M, Nganga R, Chidiac A, Hanna E, Matar S, Elston D.

Hum Vaccin Immunother. 2016 Oct 2;12(10):2501-2511. doi: 10.1080/21645515.2016.1190889. Epub 2016 Jul 25. Review.

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