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Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong.

Lui RN, Wong SH, Lau LHS, Chan TT, Cheung KCY, Li A, Chin ML, Tang W, Ching JYL, Lam KLY, Chan PKS, Wu JCY, Sung JJY, Chan FKL, Ng SC.

Hong Kong Med J. 2019 Jun;25(3):178-182. doi: 10.12809/hkmj197855. Epub 2019 May 29.


Distal versus proximal - an investigation on different supportive strategies by robots for upper limb rehabilitation after stroke: a randomized controlled trial.

Qian Q, Nam C, Guo Z, Huang Y, Hu X, Ng SC, Zheng Y, Poon W.

J Neuroeng Rehabil. 2019 Jun 3;16(1):64. doi: 10.1186/s12984-019-0537-5.


Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia.

Ooi CJ, Hilmi I, Banerjee R, Chuah SW, Ng SC, Wei SC, Makharia GK, Pisespongsa P, Chen MH, Ran ZH, Ye BD, Park DI, Ling KL, Ong D, Ahuja V, Goh KL, Sollano J, Lim WC, Leung WK, Ali RAR, Wu DC, Ong E, Mustaffa N, Limsrivilai J, Hisamatsu T, Yang SK, Ouyang Q, Geary R, De Silva JH, Rerknimitr R, Simadibrata M, Abdullah M, Leong RW; Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease and Asian Organization for Crohn’s and Colitis.

Intest Res. 2019 May 31. doi: 10.5217/ir.2019.00026. [Epub ahead of print] Review.


Escalating utilization of inpatient surgery for pelvic floor dysfunction in the elderly in Taiwan.

Ng SC, Chen CC, Cheng SH, Chen GD.

Neurourol Urodyn. 2019 May 29. doi: 10.1002/nau.24046. [Epub ahead of print]


Unusual presentation of rectal prolapse.

Ng SC, Lior T.

ANZ J Surg. 2019 May 12. doi: 10.1111/ans.15249. [Epub ahead of print] No abstract available.


HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer.

Xu C, Ooi WF, Qamra A, Tan J, Chua BY, Ho SWT, Das K, Adam Isa ZF, Li Z, Yao X, Yan T, Xing M, Huang KK, Lin JS, Nandi T, Tay ST, Lee MH, Tan ALK, Ong X, Ashktorab H, Smoot D, Li S, Ng SC, Teh BT, Tan P.

Gut. 2019 May 8. pii: gutjnl-2018-318025. doi: 10.1136/gutjnl-2018-318025. [Epub ahead of print]


Prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas.

Ng SC, Kyaw MH, Suen BY, Tse YK, Wong MCS, Hui AJ, Tak HY, Lau JYW, Sung JJY, Chan FKL.

Gut. 2019 Apr 26. pii: gutjnl-2018-318117. doi: 10.1136/gutjnl-2018-318117. [Epub ahead of print]


Diagnostic pitfalls and therapeutic outcomes of the macrofollicular variant of papillary thyroid carcinoma.

Ng SC, Huang BY, Kuo SF, Hsueh C, Chiang KC, Chen CH, Lin JD.

Biomed J. 2019 Feb;42(1):59-65. doi: 10.1016/ Epub 2019 Mar 20.


Best practices on immunomodulators and biological agents for Ulcerative colitis and Crohn's disease in Asia.

Ooi CJ, Hilmi I, Banerjee R, Chuah SW, Ng SC, Wei SC, Makharia GK, Pisespongsa P, Chen MH, Ran ZH, Ye BD, Park DI, Ling KL, Ong D, Ahuja V, Goh KL, Sollano J, Lim WC, Leung WK, Raja Ali RA, Wu DC, Ong E, Mustaffa N, Limsrivilai J, Hisamatsu T, Yang SK, Ouyang Q, Geary R, De Silva JH, Rerknimitr R, Simadibrata M, Abdullah M, Leong RWL; Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease and Asian Organization for Crohn's and Colitis.

J Gastroenterol Hepatol. 2019 Mar 8. doi: 10.1111/jgh.14648. [Epub ahead of print] Review.


Gut mucosal virome alterations in ulcerative colitis.

Zuo T, Lu XJ, Zhang Y, Cheung CP, Lam S, Zhang F, Tang W, Ching JYL, Zhao R, Chan PKS, Sung JJY, Yu J, Chan FKL, Cao Q, Sheng JQ, Ng SC.

Gut. 2019 Jul;68(7):1169-1179. doi: 10.1136/gutjnl-2018-318131. Epub 2019 Mar 6.


Evaluation of Scleroderma Clinical Trials Consortium training recommendations on modified Rodnan skin score assessment in scleroderma.

Low AHL, Ng SA, Berrocal V, Brennan B, Chan G, Ng SC, Khanna D.

Int J Rheum Dis. 2019 Mar 6. doi: 10.1111/1756-185X.13523. [Epub ahead of print]


Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling.

Chen Z, Hui PC, Hui M, Yeoh YK, Wong PY, Chan MCW, Wong MCS, Ng SC, Chan FKL, Chan PKS.

mSystems. 2019 Feb 26;4(1). pii: e00271-18. doi: 10.1128/mSystems.00271-18. eCollection 2019 Jan-Feb.


Sex-based differences in the incidence of inflammatory bowel diseases-pooled analysis of population-based studies from the Asia-Pacific region.

Shah SC, Khalili H, Chen CY, Ahn HS, Ng SC, Burisch J, Colombel JF.

Aliment Pharmacol Ther. 2019 Apr;49(7):904-911. doi: 10.1111/apt.15178. Epub 2019 Feb 17.


Trends in hospitalisation rates for inflammatory bowel disease in western versus newly industrialised countries: a population-based study of countries in the Organisation for Economic Co-operation and Development.

King JA, Underwood FE, Panaccione N, Quan J, Windsor JW, Kotze PG, Ng SC, Ghosh S, Lakatos PL, Jess T, Panaccione R, Seow CH, Ben-Horin S, Burisch J, Colombel JF, Loftus EV Jr, Gearry R, Halfvarson J, Kaplan GG.

Lancet Gastroenterol Hepatol. 2019 Apr;4(4):287-295. doi: 10.1016/S2468-1253(19)30013-5. Epub 2019 Feb 12.


Impact of inter- and intra-individual variation, sample storage and sampling fraction on human stool microbial community profiles.

Yeoh YK, Chen Z, Hui M, Wong MCS, Ho WCS, Chin ML, Ng SC, Chan FKL, Chan PKS.

PeerJ. 2019 Jan 11;7:e6172. doi: 10.7717/peerj.6172. eCollection 2019.


Traditional Chinese medicine (TCM) collaborative care for patients with axial spondyloarthritis (AcuSpA): protocol for a pragmatic randomized controlled trial.

Kwan YH, Fong W, Ang XL, Tan CS, Tai BC, Huang Y, Bilger M, Phang JK, Tan HC, Lee JV, Sun L, Tan CT, Dong BQ, Koh HL, Leung YY, Lui NL, Yeo SI, Ng SC, Fong KY, Thumboo J, Østbye T.

Trials. 2019 Jan 14;20(1):46. doi: 10.1186/s13063-018-3117-2.


Effect of far-infrared radiation on perineal wound pain and sexual function in primiparous women undergoing an episiotomy.

Huang LH, Lai YF, Chen GD, Lee MS, Ng SC.

Taiwan J Obstet Gynecol. 2019 Jan;58(1):68-71. doi: 10.1016/j.tjog.2018.11.013.


Systematic review with meta-analysis: review of donor features, procedures and outcomes in 168 clinical studies of faecal microbiota transplantation.

Lai CY, Sung J, Cheng F, Tang W, Wong SH, Chan PKS, Kamm MA, Sung JJY, Kaplan G, Chan FKL, Ng SC.

Aliment Pharmacol Ther. 2019 Feb;49(4):354-363. doi: 10.1111/apt.15116. Epub 2019 Jan 9. Review.


Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles.

Degenhardt F, Wendorff M, Wittig M, Ellinghaus E, Datta LW, Schembri J, Ng SC, Rosati E, Hübenthal M, Ellinghaus D, Jung ES, Lieb W, Abedian S, Malekzadeh R, Cheon JH, Ellul P, Sood A, Midha V, Thelma BK, Wong SH, Schreiber S, Yamazaki K, Kubo M, Boucher G, Rioux JD, Lenz TL, Brant SR, Franke A.

Hum Mol Genet. 2019 Jun 15;28(12):2078-2092. doi: 10.1093/hmg/ddy443.


Standards of diagnostic colonoscopy for early-stage neoplasia: Recommendations by an Asian private group.

Sano Y, Chiu HM, Li XB, Khomvilai S, Pisespongsa P, Co JT, Kawamura T, Kobayashi N, Tanaka S, Hewett DG, Takeuchi Y, Imai K, Utsumi T, Teramoto A, Hirata D, Iwatate M, Singh R, Ng SC, Ho SH, Chiu P, Tajiri H.

Dig Endosc. 2019 May;31(3):227-244. doi: 10.1111/den.13330. Epub 2019 Mar 29.


Risk of tuberculosis in patients with immune-mediated diseases on biological therapies: a population-based study in a tuberculosis endemic region.

Wang X, Wong SH, Wang XS, Tang W, Liu CQ, Niamul G, Wu B, Tam LS, Wu JCY, Chan FKL, Sung JJY, Ng SC.

Rheumatology (Oxford). 2018 Dec 14. doi: 10.1093/rheumatology/key364. [Epub ahead of print]


Risk of Postpolypectomy Bleeding With Uninterrupted Clopidogrel Therapy in an Industry-Independent, Double-Blind, Randomized Trial.

Chan FKL, Kyaw MH, Hsiang JC, Suen BY, Kee KM, Tse YK, Ching JYL, Cheong PK, Ng D, Lam K, Lo A, Lee V, Ng SC.

Gastroenterology. 2019 Mar;156(4):918-925.e1. doi: 10.1053/j.gastro.2018.10.036. Epub 2018 Oct 25.


Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer.

Coker OO, Nakatsu G, Dai RZ, Wu WKK, Wong SH, Ng SC, Chan FKL, Sung JJY, Yu J.

Gut. 2019 Apr;68(4):654-662. doi: 10.1136/gutjnl-2018-317178. Epub 2018 Nov 24.


New approaches along the IBD course: diet, tight control and stem cells.

Ng SC, Ananthakrishnan AN.

Nat Rev Gastroenterol Hepatol. 2019 Feb;16(2):82-84. doi: 10.1038/s41575-018-0088-4. No abstract available.


Impact of the Receptor for Advanced Glycation End Products Genetic Polymorphisms on the Progression in Uterine Cervical Cancer.

Lee CY, Ng SC, Hsiao YH, Yang SF, Hsu CF, Wang PH.

J Cancer. 2018 Oct 10;9(21):3886-3893. doi: 10.7150/jca.27960. eCollection 2018.


The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease.

Zuo T, Ng SC.

Front Microbiol. 2018 Sep 25;9:2247. doi: 10.3389/fmicb.2018.02247. eCollection 2018. Review.


Low Frequency of Opportunistic Infections in Patients Receiving Vedolizumab in Clinical Trials and Post-Marketing Setting.

Ng SC, Hilmi IN, Blake A, Bhayat F, Adsul S, Khan QR, Wu DC.

Inflamm Bowel Dis. 2018 Oct 12;24(11):2431-2441. doi: 10.1093/ibd/izy153.


International Validation of the Eighth Edition of the American Joint Committee on Cancer (AJCC) TNM Staging System in Patients With Resected Pancreatic Cancer.

van Roessel S, Kasumova GG, Verheij J, Najarian RM, Maggino L, de Pastena M, Malleo G, Marchegiani G, Salvia R, Ng SC, de Geus SW, Lof S, Giovinazzo F, van Dam JL, Kent TS, Busch OR, van Eijck CH, Koerkamp BG, Abu Hilal M, Bassi C, Tseng JF, Besselink MG.

JAMA Surg. 2018 Dec 1;153(12):e183617. doi: 10.1001/jamasurg.2018.3617. Epub 2018 Dec 19.


A Global Survey of Gastroenterologists' Travel Advice to Patients with Inflammatory Bowel Disease on Immunosuppressive Agents and Management of Those Visiting Tuberculosis-Endemic Areas.

Chan W, Shim HH, Ng SC; Asia–Pacific Crohn’s and Colitis Epidemiologic Study (ACCESS) Study Group, Liu J, Inglis C, Greveson K, Baraty B, Haifer C, Leong RWL.

J Crohns Colitis. 2018 Nov 15;12(11):1261-1269. doi: 10.1093/ecco-jcc/jjy110.


Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection.

Zuo T, Wong SH, Cheung CP, Lam K, Lui R, Cheung K, Zhang F, Tang W, Ching JYL, Wu JCY, Chan PKS, Sung JJY, Yu J, Chan FKL, Ng SC.

Nat Commun. 2018 Sep 10;9(1):3663. doi: 10.1038/s41467-018-06103-6.


Adaptive template matching of photoplethysmogram pulses to detect motion artefact.

Lim PK, Ng SC, Lovell NH, Yu YP, Tan MP, McCombie D, Lim E, Redmond SJ.

Physiol Meas. 2018 Oct 11;39(10):105005. doi: 10.1088/1361-6579/aadf1e.


Population Density and Risk of Inflammatory Bowel Disease: A Prospective Population-Based Study in 13 Countries or Regions in Asia-Pacific.

Ng SC, Kaplan GG, Tang W, Banerjee R, Adigopula B, Underwood FE, Tanyingoh D, Wei SC, Lin WC, Lin HH, Li J, Bell S, Niewiadomski O, Kamm MA, Zeng Z, Chen M, Hu P, Ong D, Ooi CJ, Ling KL, Miao Y, Miao J, Janaka de Silva H, Niriella M, Aniwan S, Limsrivilai J, Pisespongsa P, Wu K, Yang H, Ng KK, Yu HH, Wang Y, Ouyang Q, Abdullah M, Simadibrata M, Gunawan J, Hilmi I, Lee Goh K, Cao Q, Sheng H, Ong-Go A, Chong VH, Ching JYL, Wu JCY, Chan FKL, Sung JJY.

Am J Gastroenterol. 2019 Jan;114(1):107-115. doi: 10.1038/s41395-018-0233-2.


Significant Medical and Surgical Morbidity in Perianal Crohn's Disease: Results from a Territory-Wide Study.

Mak WY, Mak OS, Lee CK, Tang W, Leung WK, Wong MTL, Sze ASF, Li M, Leung CM, Lo FH, Lam BCY, Chan KH, Shan EHS, Tsang SWC, Hui AJ, Chow WH, Chan FKL, Sung JJY, Ng SC.

J Crohns Colitis. 2018 Nov 28;12(12):1392-1398. doi: 10.1093/ecco-jcc/jjy120.


An Overview on Image Registration Techniques for Cardiac Diagnosis and Treatment.

Khalil A, Ng SC, Liew YM, Lai KW.

Cardiol Res Pract. 2018 Aug 8;2018:1437125. doi: 10.1155/2018/1437125. eCollection 2018. Review.


The changing epidemiology of liver diseases in the Asia-Pacific region.

Wong MCS, Huang JLW, George J, Huang J, Leung C, Eslam M, Chan HLY, Ng SC.

Nat Rev Gastroenterol Hepatol. 2019 Jan;16(1):57-73. doi: 10.1038/s41575-018-0055-0. Review.


The association between new generation oral contraceptive pill and the development of inflammatory bowel diseases.

Sanagapalli S, Ko Y, Kariyawasam V, Ng SC, Tang W, de Silva HJ, Chen M, Wu K, Aniwan S, Ng KK, Ong D, Ouyang Q, Hilmi I, Simadibrata M, Pisespongsa P, Gopikrishna S, Leong RW; IBD Sydney Organisation and the Asia-Pacific Crohn's and Colitis Epidemiology Study (ACCESS) Group.

Intest Res. 2018 Jul;16(3):409-415. doi: 10.5217/ir.2018.16.3.409. Epub 2018 Jul 27.


Gastrointestinal disease burden and mortality: A public hospital-based study from 2005 to 2014.

Chan JSH, Chao ACW, Cheung VCH, Wong SSK, Tang W, Wu JCY, Chan HLY, Chan FKL, Sung JJY, Ng SC.

J Gastroenterol Hepatol. 2019 Jan;34(1):124-131. doi: 10.1111/jgh.14377. Epub 2018 Jul 30.


The state of the art on treatment of Crohn's disease.

Shi HY, Ng SC.

J Gastroenterol. 2018 Sep;53(9):989-998. doi: 10.1007/s00535-018-1479-6. Epub 2018 Jul 6. Review.


Sex-Based Differences in Incidence of Inflammatory Bowel Diseases-Pooled Analysis of Population-Based Studies From Western Countries.

Shah SC, Khalili H, Gower-Rousseau C, Olen O, Benchimol EI, Lynge E, Nielsen KR, Brassard P, Vutcovici M, Bitton A, Bernstein CN, Leddin D, Tamim H, Stefansson T, Loftus EV Jr, Moum B, Tang W, Ng SC, Gearry R, Sincic B, Bell S, Sands BE, Lakatos PL, Végh Z, Ott C, Kaplan GG, Burisch J, Colombel JF.

Gastroenterology. 2018 Oct;155(4):1079-1089.e3. doi: 10.1053/j.gastro.2018.06.043. Epub 2018 Jun 27.


Surface Properties Determining Passage Rates of Proteins through Nuclear Pores.

Frey S, Rees R, Schünemann J, Ng SC, Fünfgeld K, Huyton T, Görlich D.

Cell. 2018 Jun 28;174(1):202-217.e9. doi: 10.1016/j.cell.2018.05.045.


Risk factors for advanced colorectal neoplasms in the proximal colon in 6218 subjects undergoing complete colonoscopy.

Hirai HW, Ching JYL, Wu JCY, Sung JJY, Chan FKL, Ng SC.

J Gastroenterol Hepatol. 2019 Jan;34(1):113-119. doi: 10.1111/jgh.14357. Epub 2018 Jul 12.



Ananthakrishnan AN, Ng SC.

Clin Gastroenterol Hepatol. 2018 Jul;16(7):1177. doi: 10.1016/j.cgh.2018.03.015. No abstract available.


Proteus spp. as Putative Gastrointestinal Pathogens.

Hamilton AL, Kamm MA, Ng SC, Morrison M.

Clin Microbiol Rev. 2018 Jun 13;31(3). pii: e00085-17. doi: 10.1128/CMR.00085-17. Print 2018 Jul. Review.


Anastomotic leaks in stage IV colorectal cancer.

Ng SC, Stupart D, Bartolo D, Watters D.

ANZ J Surg. 2018 Sep;88(9):E649-E653. doi: 10.1111/ans.14494. Epub 2018 Jun 12.


A Prospective Study to Monitor for Tuberculosis During Anti-tumour Necrosis Factor Therapy in Patients With Inflammatory Bowel Disease and Immune-mediated Inflammatory Diseases.

Lee CK, Wong SHV, Lui G, Tang W, Tam LS, Ip M, Hung E, Chen M, Wu JC, Ng SC.

J Crohns Colitis. 2018 Jul 30;12(8):954-962. doi: 10.1093/ecco-jcc/jjy057.


Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer.

Kwong TNY, Wang X, Nakatsu G, Chow TC, Tipoe T, Dai RZW, Tsoi KKK, Wong MCS, Tse G, Chan MTV, Chan FKL, Ng SC, Wu JCY, Wu WKK, Yu J, Sung JJY, Wong SH.

Gastroenterology. 2018 Aug;155(2):383-390.e8. doi: 10.1053/j.gastro.2018.04.028. Epub 2018 May 3.


Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes.

Nakatsu G, Zhou H, Wu WKK, Wong SH, Coker OO, Dai Z, Li X, Szeto CH, Sugimura N, Lam TY, Yu AC, Wang X, Chen Z, Wong MC, Ng SC, Chan MTV, Chan PKS, Chan FKL, Sung JJ, Yu J.

Gastroenterology. 2018 Aug;155(2):529-541.e5. doi: 10.1053/j.gastro.2018.04.018. Epub 2018 Apr 22.


Urbanization and the gut microbiota in health and inflammatory bowel disease.

Zuo T, Kamm MA, Colombel JF, Ng SC.

Nat Rev Gastroenterol Hepatol. 2018 Jul;15(7):440-452. doi: 10.1038/s41575-018-0003-z. Review.


Pathological Margin Clearance and Survival After Pancreaticoduodenectomy in a US and European Pancreatic Center.

van Roessel S, Kasumova GG, Tabatabaie O, Ng SC, van Rijssen LB, Verheij J, Najarian RM, van Gulik TM, Besselink MG, Busch OR, Tseng JF.

Ann Surg Oncol. 2018 Jun;25(6):1760-1767. doi: 10.1245/s10434-018-6467-9. Epub 2018 Apr 12.


Editorial: ways to reduce emergency department utilisation among IBD patients.

Mak WY, Ng SC.

Aliment Pharmacol Ther. 2018 May;47(9):1325-1326. doi: 10.1111/apt.14601. No abstract available.


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