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Development and Validation of Apolipoprotein AI-Associated Lipoprotein Proteome Panel for the Prediction of Cholesterol Efflux Capacity and Coronary Artery Disease.

Jin Z, Collier TS, Dai DLY, Chen V, Hollander Z, Ng RT, McManus BM, Balshaw R, Apostolidou S, Penn MS, Bystrom C.

Clin Chem. 2019 Feb;65(2):282-290. doi: 10.1373/clinchem.2018.291922. Epub 2018 Nov 21.


Excellent 10-year patient-reported outcomes and survival in a single-radius, cruciate-retaining total knee arthroplasty.

Scott CEH, Bell KR, Ng RT, MacDonald DJ, Patton JT, Burnett R.

Knee Surg Sports Traumatol Arthrosc. 2018 Oct 1. doi: 10.1007/s00167-018-5179-9. [Epub ahead of print]


Vitamin D non-sufficiency is prevalent in children with chronic liver disease in a tropical country.

Lee WS, Jalaludin MY, Wong SY, Ong SY, Foo HW, Ng RT.

Pediatr Neonatol. 2019 Feb;60(1):12-18. doi: 10.1016/j.pedneo.2018.03.011. Epub 2018 Apr 5.


Quality indicators in pediatric colonoscopy in a low-volume center: Implications for training.

Lee WS, Tee CW, Koay ZL, Wong TS, Zahraq F, Foo HW, Ong SY, Wong SY, Ng RT.

World J Gastroenterol. 2018 Mar 7;24(9):1013-1021. doi: 10.3748/wjg.v24.i9.1013.


Inferring RNA sequence preferences for poorly studied RNA-binding proteins based on co-evolution.

Yang S, Wang J, Ng RT.

BMC Bioinformatics. 2018 Mar 12;19(1):96. doi: 10.1186/s12859-018-2091-8.


Phenotyping COPD exacerbations using imaging and blood-based biomarkers.

Alotaibi NM, Chen V, Hollander Z, Hague CJ, Murphy DT, Leipsic JA, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 8;13:217-229. doi: 10.2147/COPD.S152484. eCollection 2018.


Complementary and alternative medicine (CAM) practices and dietary patterns in children with inflammatory bowel disease in Singapore and Malaysia.

Ong F, Seah Lee W, Lin C, Ng RT, Yee Wong S, Lim SL, Quak SH, Aw M.

Pediatr Neonatol. 2018 Oct;59(5):494-500. doi: 10.1016/j.pedneo.2017.12.007. Epub 2017 Dec 26.


Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation.

Sukma Dewi I, Gidlöf O, Hollander Z, Lam KK, Benson MD, Braun OO, Nilsson J, Tebbutt SJ, Ng RT, Öhman J, McManus BM, Smith JG.

J Am Coll Cardiol. 2017 Dec 12;70(23):2946-2947. doi: 10.1016/j.jacc.2017.10.012. No abstract available.


Chronic liver disease is universal in children with biliary atresia living with native liver.

Lee WS, Ong SY, Foo HW, Wong SY, Kong CX, Seah RB, Ng RT.

World J Gastroenterol. 2017 Nov 21;23(43):7776-7784. doi: 10.3748/wjg.v23.i43.7776.


Multiple reaction monitoring mass spectrometry to identify novel plasma protein biomarkers of treatment response in cystic fibrosis pulmonary exacerbations.

Roberts JM, Dai DLY, Hollander Z, Ng RT, Tebbutt SJ, Wilcox PG, Sin DD, Quon BS.

J Cyst Fibros. 2018 May;17(3):333-340. doi: 10.1016/j.jcf.2017.10.013. Epub 2017 Nov 22.


Fatal infections in older patients with inflammatory bowel disease on anti-tumor necrosis factor therapy.

Lee WS, Azmi N, Ng RT, Ong SY, Ponnampalavanar SS, Mahadeva S, Hilmi I.

Intest Res. 2017 Oct;15(4):524-528. doi: 10.5217/ir.2017.15.4.524. Epub 2017 Oct 23.


Differentiating heart failure phenotypes using sex-specific transcriptomic and proteomic biomarker panels.

Toma M, Mak GJ, Chen V, Hollander Z, Shannon CP, Lam KKY, Ng RT, Tebbutt SJ, Wilson-McManus JE, Ignaszewski A, Anderson T, Dyck JRB, Howlett J, Ezekowitz J, McManus BM, Oudit GY.

ESC Heart Fail. 2017 Aug;4(3):301-311. doi: 10.1002/ehf2.12136. Epub 2017 Mar 4.


PGCA: An algorithm to link protein groups created from MS/MS data.

Kepplinger D, Takhar M, Sasaki M, Hollander Z, Smith D, McManus B, McMaster WR, Ng RT, Cohen Freue GV.

PLoS One. 2017 May 31;12(5):e0177569. doi: 10.1371/journal.pone.0177569. eCollection 2017.


Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers.

Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, Miller BE, Rennard S, Spira A, Hackett TL, Lam W, Lam S, Faner R, Agusti A, Hogg JC, Sin DD, Paré PD.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):411-418. doi: 10.1165/rcmb.2016-0284OC.


Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease.

Obeidat M, Nie Y, Chen V, Shannon CP, Andiappan AK, Lee B, Rotzschke O, Castaldi PJ, Hersh CP, Fishbane N, Ng RT, McManus B, Miller BE, Rennard S, Paré PD, Sin DD.

Respir Res. 2017 Apr 24;18(1):72. doi: 10.1186/s12931-017-0558-1.


C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations.

Chen YR, Chen V, Hollander Z, Leipsic JA, Hague CJ, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

PLoS One. 2017 Mar 22;12(3):e0174063. doi: 10.1371/journal.pone.0174063. eCollection 2017.


Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation.

Sukma Dewi I, Hollander Z, Lam KK, McManus JW, Tebbutt SJ, Ng RT, Keown PA, McMaster RW, McManus BM, Gidlöf O, Öhman J.

PLoS One. 2017 Jan 26;12(1):e0170842. doi: 10.1371/journal.pone.0170842. eCollection 2017.


Variable outcome in infantile-onset inflammatory bowel disease in an Asian cohort.

Lee WS, Ng RT, Chan KW, Lau YL.

World J Gastroenterol. 2016 Dec 28;22(48):10653-10662. doi: 10.3748/wjg.v22.i48.10653.


Enumerateblood - an R package to estimate the cellular composition of whole blood from Affymetrix Gene ST gene expression profiles.

Shannon CP, Balshaw R, Chen V, Hollander Z, Toma M, McManus BM, FitzGerald JM, Sin DD, Ng RT, Tebbutt SJ.

BMC Genomics. 2017 Jan 6;18(1):43. doi: 10.1186/s12864-016-3460-1.


SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations.

Shannon CP, Chen V, Takhar M, Hollander Z, Balshaw R, McManus BM, Tebbutt SJ, Sin DD, Ng RT.

BMC Bioinformatics. 2016 Nov 14;17(1):460.


Transcutaneous electrical stimulation (TES) for treatment of constipation in children.

Ng RT, Lee WS, Ang HL, Teo KM, Yik YI, Lai NM.

Cochrane Database Syst Rev. 2016 Nov 11;11:CD010873. Review.


WITHDRAWN: Transcutaneous electrical stimulation (TES) for treatment of constipation in children.

Ng RT, Lee WS, Ang HL, Teo KM, Yik YI, Lai NM.

Cochrane Database Syst Rev. 2016 Oct 12;10:CD010873. Review. Update in: Cochrane Database Syst Rev. 2016 Nov 11;11:CD010873.


Biomarker Development in COPD: Moving From P Values to Products to Impact Patient Care.

Hollander Z, DeMarco ML, Sadatsafavi M, McManus BM, Ng RT, Sin DD.

Chest. 2017 Feb;151(2):455-467. doi: 10.1016/j.chest.2016.09.012. Epub 2016 Sep 29. Review.


COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry.

Leung JM, Chen V, Hollander Z, Dai D, Tebbutt SJ, Aaron SD, Vandemheen KL, Rennard SI, FitzGerald JM, Woodruff PG, Lazarus SC, Connett JE, Coxson HO, Miller B, Borchers C, McManus BM, Ng RT, Sin DD.

PLoS One. 2016 Aug 15;11(8):e0161129. doi: 10.1371/journal.pone.0161129. eCollection 2016.


Transcutaneous electrical stimulation (TES) for treatment of constipation in children.

Ng RT, Lee WS, Ang HL, Teo KM, Yik YI, Lai NM.

Cochrane Database Syst Rev. 2016 Jul 5;7:CD010873. doi: 10.1002/14651858.CD010873.pub2. Review.


The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease.

Obeidat M, Ding X, Fishbane N, Hollander Z, Ng RT, McManus B, Tebbutt SJ, Miller BE, Rennard S, Paré PD, Sin DD.

Nicotine Tob Res. 2016 Sep;18(9):1903-9. doi: 10.1093/ntr/ntw129. Epub 2016 May 6.


Novel mutations in SKIV2L and TTC37 genes in Malaysian children with trichohepatoenteric syndrome.

Lee WS, Teo KM, Ng RT, Chong SY, Kee BP, Chua KH.

Gene. 2016 Jul 15;586(1):1-6. doi: 10.1016/j.gene.2016.03.049. Epub 2016 Apr 12.


The Effect of Statins on Blood Gene Expression in COPD.

Obeidat M, Fishbane N, Nie Y, Chen V, Hollander Z, Tebbutt SJ, Bossé Y, Ng RT, Miller BE, McManus B, Rennard S, Paré PD, Sin DD.

PLoS One. 2015 Oct 13;10(10):e0140022. doi: 10.1371/journal.pone.0140022. eCollection 2015.


Biomarker Development for Chronic Obstructive Pulmonary Disease. From Discovery to Clinical Implementation.

Sin DD, Hollander Z, DeMarco ML, McManus BM, Ng RT.

Am J Respir Crit Care Med. 2015 Nov 15;192(10):1162-70. doi: 10.1164/rccm.201505-0871PP.


High levels of sound pressure: acoustic reflex thresholds and auditory complaints of workers with noise exposure.

Duarte AS, Ng RT, de Carvalho GM, Guimarães AC, Pinheiro LA, Costa EA, Gusmão RJ.

Braz J Otorhinolaryngol. 2015 Jul-Aug;81(4):374-83. doi: 10.1016/j.bjorl.2014.07.017. Epub 2015 Jun 9.


Characteristics and outcome of autoimmune liver disease in Asian children.

Lee WS, Lum SH, Lim CB, Chong SY, Khoh KM, Ng RT, Teo KM, Boey CC, Pailoor J.

Hepatol Int. 2015 Apr;9(2):292-302. doi: 10.1007/s12072-014-9558-0. Epub 2014 Aug 6.


Discovery of novel plasma protein biomarkers to predict imminent cystic fibrosis pulmonary exacerbations using multiple reaction monitoring mass spectrometry.

Quon BS, Dai DL, Hollander Z, Ng RT, Tebbutt SJ, Man SF, Wilcox PG, Sin DD.

Thorax. 2016 Mar;71(3):216-22. doi: 10.1136/thoraxjnl-2014-206710. Epub 2015 Mar 16.


Audiogram comparison of workers from five professional categories.

Duarte AS, Guimarães AC, de Carvalho GM, Pinheiro LA, Ng RT, Sampaio MH, da Costa EA, Gusmão RJ.

Biomed Res Int. 2015;2015:201494. doi: 10.1155/2015/201494. Epub 2015 Feb 3.


Nasal potential difference in cystic fibrosis considering severe CFTR mutations.

Ng RT, Marson FA, Ribeiro JD, Ribeiro AF, Bertuzzo CS, Ribeiro MA, Severino SD, Sakano E.

Dis Markers. 2015;2015:306825. doi: 10.1155/2015/306825. Epub 2015 Jan 15.


Novel multivariate methods for integration of genomics and proteomics data: applications in a kidney transplant rejection study.

Günther OP, Shin H, Ng RT, McMaster WR, McManus BM, Keown PA, Tebbutt SJ, Lê Cao KA.

OMICS. 2014 Nov;18(11):682-95. doi: 10.1089/omi.2014.0062.


Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection.

Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ.

PLoS One. 2014 Apr 14;9(4):e95224. doi: 10.1371/journal.pone.0095224. eCollection 2014.


Variation in RNA-Seq transcriptome profiles of peripheral whole blood from healthy individuals with and without globin depletion.

Shin H, Shannon CP, Fishbane N, Ruan J, Zhou M, Balshaw R, Wilson-McManus JE, Ng RT, McManus BM, Tebbutt SJ; PROOF Centre of Excellence Team.

PLoS One. 2014 Mar 7;9(3):e91041. doi: 10.1371/journal.pone.0091041. eCollection 2014.


Proteomic biomarkers of recovered heart function.

Hollander Z, Lazárová M, Lam KK, Ignaszewski A, Oudit GY, Dyck JR, Schreiner G, Pauwels J, Chen V, Cohen Freue GV, Ng RT, Wilson-McManus JE, Balshaw R, Tebbutt SJ, McMaster RW, Keown PA, McManus BM; NCE CECR PROOF Prevention of Organ Failure (PROOF) Centre of Excellence.

Eur J Heart Fail. 2014 May;16(5):551-9. doi: 10.1002/ejhf.65. Epub 2014 Feb 23.


Longitudinal analysis of whole blood transcriptomes to explore molecular signatures associated with acute renal allograft rejection.

Shin H, Günther O, Hollander Z, Wilson-McManus JE, Ng RT, Balshaw R, Keown PA, McMaster R, McManus BM, Isbel NM, Knoll G, Tebbutt SJ.

Bioinform Biol Insights. 2014 Jan 22;8:17-33. doi: 10.4137/BBI.S13376.. eCollection 2014.


Plasma protein biosignatures for detection of cardiac allograft vasculopathy.

Lin D, Cohen Freue G, Hollander Z, John Mancini GB, Sasaki M, Mui A, Wilson-McManus J, Ignaszewski A, Imai C, Meredith A, Balshaw R, Ng RT, Keown PA, Robert McMaster W, Carere R, Webb JG, McManus BM; Biomarkers in Transplantation Team; Networks of Centres of Excellence, Centres of Excellence for Commercialization and Research-Prevention of Organ Failure Centre of Excellence.

J Heart Lung Transplant. 2013 Jul;32(7):723-33. doi: 10.1016/j.healun.2013.04.011.


Computational biomarker pipeline from discovery to clinical implementation: plasma proteomic biomarkers for cardiac transplantation.

Cohen Freue GV, Meredith A, Smith D, Bergman A, Sasaki M, Lam KK, Hollander Z, Opushneva N, Takhar M, Lin D, Wilson-McManus J, Balshaw R, Keown PA, Borchers CH, McManus B, Ng RT, McMaster WR; Biomarkers in Transplantation and the NCE CECR Prevention of Organ Failure Centre of Excellence Teams.

PLoS Comput Biol. 2013 Apr;9(4):e1002963. doi: 10.1371/journal.pcbi.1002963. Epub 2013 Apr 4.


Predicting acute cardiac rejection from donor heart and pre-transplant recipient blood gene expression.

Hollander Z, Chen V, Sidhu K, Lin D, Ng RT, Balshaw R, Cohen-Freue GV, Ignaszewski A, Imai C, Kaan A, Tebbutt SJ, Wilson-McManus JE, McMaster RW, Keown PA, McManus BM; NCE CECR PROOF Centre of Excellence.

J Heart Lung Transplant. 2013 Feb;32(2):259-65. doi: 10.1016/j.healun.2012.11.008. Epub 2012 Dec 21.


A computational pipeline for the development of multi-marker bio-signature panels and ensemble classifiers.

Günther OP, Chen V, Freue GC, Balshaw RF, Tebbutt SJ, Hollander Z, Takhar M, McMaster WR, McManus BM, Keown PA, Ng RT.

BMC Bioinformatics. 2012 Dec 8;13:326. doi: 10.1186/1471-2105-13-326.


White blood cell differentials enrich whole blood expression data in the context of acute cardiac allograft rejection.

Shannon CP, Hollander Z, Wilson-McManus J, Balshaw R, Ng RT, McMaster R, McManus BM, Keown PA, Tebbutt SJ.

Bioinform Biol Insights. 2012;6:49-61. doi: 10.4137/BBI.S9197. Epub 2012 Apr 10.


Molecular signatures of end-stage heart failure.

Lin D, Hollander Z, Meredith A, Stadnick E, Sasaki M, Cohen Freue G, Qasimi P, Mui A, Ng RT, Balshaw R, Wilson-McManus JE, Wishart D, Hau D, Keown PA, McMaster R, McManus BM; Biomarkers in Transplantation Team; NCE CECR PROOF Centre of Excellence.

J Card Fail. 2011 Oct;17(10):867-74. doi: 10.1016/j.cardfail.2011.07.001. Epub 2011 Sep 3.


Microbiology of rhinosinusitis in immunosupressed patients from the University Hospital.

Ortiz E, Ng RT, Alliegro FC, Teixeira C, Muranaka EB, Sakano E.

Braz J Otorhinolaryngol. 2011 Jul-Aug;77(4):522-5. English, Portuguese.


Long non-coding RNAs are expressed in oral mucosa and altered in oral premalignant lesions.

Gibb EA, Enfield KS, Stewart GL, Lonergan KM, Chari R, Ng RT, Zhang L, MacAulay CE, Rosin MP, Lam WL.

Oral Oncol. 2011 Nov;47(11):1055-61. doi: 10.1016/j.oraloncology.2011.07.008. Epub 2011 Aug 10.


ChemModLab: a web-based cheminformatics modeling laboratory.

Hughes-Oliver JM, Brooks AD, Welch WJ, Khaledi MG, Hawkins D, Young SS, Patil K, Howell GW, Ng RT, Chu MT.

In Silico Biol. 2011-2012;11(1-2):61-81. doi: 10.3233/CI-2008-0016.


Effects of sample timing and treatment on gene expression in early acute renal allograft rejection.

Günther OP, Lin D, Balshaw RF, Ng RT, Hollander Z, Wilson-McManus J, McMaster WR, McManus BM, Keown PA; Biomarkers in Transplantation Team.

Transplantation. 2011 Feb 15;91(3):323-9. doi: 10.1097/TP.0b013e3182029b16.


Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection.

Garmaroudi FS, Marchant D, Si X, Khalili A, Bashashati A, Wong BW, Tabet A, Ng RT, Murphy K, Luo H, Janes KA, McManus BM.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):17053-8. doi: 10.1073/pnas.1006478107. Epub 2010 Sep 10.

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