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Items: 1 to 50 of 113

1.

Multi-modal image cytometry approach - From dynamic to whole organ imaging.

Husna N, Gascoigne NRJ, Tey HL, Ng LG, Tan Y.

Cell Immunol. 2019 Jul 2:103946. doi: 10.1016/j.cellimm.2019.103946. [Epub ahead of print]

PMID:
31300150
2.

Dengue virus-elicited tryptase induces endothelial permeability and shock.

Rathore AP, Mantri CK, Aman SA, Syenina A, Ooi J, Jagaraj CJ, Goh CC, Tissera H, Wilder-Smith A, Ng LG, Gubler DJ, St John AL.

J Clin Invest. 2019 Jul 2;130. pii: 128426. doi: 10.1172/JCI128426.

3.

Granulopoiesis and Neutrophil Homeostasis: A Metabolic, Daily Balancing Act.

Yvan-Charvet L, Ng LG.

Trends Immunol. 2019 Jul;40(7):598-612. doi: 10.1016/j.it.2019.05.004. Review.

PMID:
31256783
4.

PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.

Bianchini M, Duchêne J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA.

Sci Immunol. 2019 Jun 21;4(36). pii: eaar3054. doi: 10.1126/sciimmunol.aar3054.

PMID:
31227596
5.

Capturing the Fantastic Voyage of Monocytes Through Time and Space.

Teh YC, Ding JL, Ng LG, Chong SZ.

Front Immunol. 2019 Apr 16;10:834. doi: 10.3389/fimmu.2019.00834. eCollection 2019. Review.

6.

"Cloaking" on Time: A Cover-Up Act by Resident Tissue Macrophages.

Blériot C, Ng LG, Ginhoux F.

Cell. 2019 Apr 18;177(3):514-516. doi: 10.1016/j.cell.2019.03.042.

PMID:
31002790
7.

A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.

Janela B, Patel AA, Lau MC, Goh CC, Msallam R, Kong WT, Fehlings M, Hubert S, Lum J, Simoni Y, Malleret B, Zolezzi F, Chen J, Poidinger M, Satpathy AT, Briseno C, Wohn C, Malissen B, Murphy KM, Maini AA, Vanhoutte L, Guilliams M, Vial E, Hennequin L, Newell E, Ng LG, Musette P, Yona S, Hacini-Rachinel F, Ginhoux F.

Immunity. 2019 Apr 16;50(4):1069-1083.e8. doi: 10.1016/j.immuni.2019.03.001. Epub 2019 Mar 27.

PMID:
30926233
8.

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.

Chakarov S, Lim HY, Tan L, Lim SY, See P, Lum J, Zhang XM, Foo S, Nakamizo S, Duan K, Kong WT, Gentek R, Balachander A, Carbajo D, Bleriot C, Malleret B, Tam JKC, Baig S, Shabeer M, Toh SES, Schlitzer A, Larbi A, Marichal T, Malissen B, Chen J, Poidinger M, Kabashima K, Bajenoff M, Ng LG, Angeli V, Ginhoux F.

Science. 2019 Mar 15;363(6432). pii: eaau0964. doi: 10.1126/science.aau0964.

PMID:
30872492
9.

In vivo label-free functional photoacoustic monitoring of ischemic reperfusion.

Bi R, Dinish US, Goh CC, Imai T, Moothanchery M, Li X, Kim JY, Jeon S, Pu Y, Kim C, Ng LG, Wang LV, Olivo M.

J Biophotonics. 2019 Jul;12(7):e201800454. doi: 10.1002/jbio.201800454. Epub 2019 Apr 1.

PMID:
30865386
10.

Evolving trends in the surgical management of renal masses over the past two decades: A contemporary picture from a large prospectively-maintained database.

Chen K, Lee A, Huang HH, Tay KJ, Sim A, Lee LS, Cheng CWS, Ng LG, Ho HSS, Yuen JSP.

Int J Urol. 2019 Apr;26(4):465-474. doi: 10.1111/iju.13909. Epub 2019 Feb 28.

PMID:
30818418
11.

Heterogeneity of neutrophils.

Ng LG, Ostuni R, Hidalgo A.

Nat Rev Immunol. 2019 Apr;19(4):255-265. doi: 10.1038/s41577-019-0141-8. Review.

PMID:
30816340
12.

Polymerization-Enhanced Two-Photon Photosensitization for Precise Photodynamic Therapy.

Wang S, Wu W, Manghnani P, Xu S, Wang Y, Goh CC, Ng LG, Liu B.

ACS Nano. 2019 Mar 26;13(3):3095-3105. doi: 10.1021/acsnano.8b08398. Epub 2019 Feb 18.

PMID:
30763072
13.

'Pop goes the whistle' - Noisy micturition as the main presentation of pneumaturia.

Khor V, Aslim EJ, Ng LG, Lim JKS.

Urol Case Rep. 2019 Jan 19;23:106-107. doi: 10.1016/j.eucr.2019.01.013. eCollection 2019 Mar. No abstract available.

14.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29.

PMID:
30709741
15.

Two Weeks Too Long: Optimal Duration for Ureteral Prestenting and Its Physiologic Effects on the Ureter in a Yorkshire-Landrace Pig Model.

Lim KS, Lim YW, Yong DZP, Hao Y, Ho HSS, Ng LG, Sim ASP.

J Endourol. 2019 Apr;33(4):325-330. doi: 10.1089/end.2018.0872. Epub 2019 Mar 20.

PMID:
30672310
16.

Neutrophil: A mobile fertilizer.

Ng LG.

J Exp Med. 2019 Jan 7;216(1):4-6. doi: 10.1084/jem.20182059. Epub 2018 Dec 19.

17.

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Lim HY, Lim SY, Tan CK, Thiam CH, Goh CC, Carbajo D, Chew SHS, See P, Chakarov S, Wang XN, Lim LH, Johnson LA, Lum J, Fong CY, Bongso A, Biswas A, Goh C, Evrard M, Yeo KP, Basu R, Wang JK, Tan Y, Jain R, Tikoo S, Choong C, Weninger W, Poidinger M, Stanley ER, Collin M, Tan NS, Ng LG, Jackson DG, Ginhoux F, Angeli V.

Immunity. 2018 Dec 18;49(6):1191. doi: 10.1016/j.immuni.2018.12.009. No abstract available.

PMID:
30566884
18.

Dimensionality reduction for visualizing single-cell data using UMAP.

Becht E, McInnes L, Healy J, Dutertre CA, Kwok IWH, Ng LG, Ginhoux F, Newell EW.

Nat Biotechnol. 2018 Dec 3. doi: 10.1038/nbt.4314. [Epub ahead of print]

PMID:
30531897
19.

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells.

Loh JT, Lim TJF, Ikumi K, Matoba T, Janela B, Gunawan M, Toyama T, Bunjamin M, Ng LG, Poidinger M, Morita A, Ginhoux F, Yamazaki S, Lam KP, Su IH.

iScience. 2018 Dec 21;10:23-39. doi: 10.1016/j.isci.2018.11.019. Epub 2018 Nov 14.

20.

3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation.

Tan Y, Ng WJ, Lee SZX, Lee BTK, Nattkemper LA, Yosipovitch G, Ng LG, Tey HL.

J Invest Dermatol. 2019 May;139(5):1201-1204. doi: 10.1016/j.jid.2018.11.006. Epub 2018 Nov 22. No abstract available.

PMID:
30471253
21.

Neutrophils instruct homeostatic and pathological states in naive tissues.

Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A.

J Exp Med. 2018 Nov 5;215(11):2778-2795. doi: 10.1084/jem.20181468. Epub 2018 Oct 3.

22.

Streamlining volumetric multi-channel image cytometry using hue-saturation-brightness-based surface creation.

Tan Y, Li JLY, Goh CC, Lee BTK, Kwok IWH, Ng WJ, Evrard M, Poidinger M, Tey HL, Ng LG.

Commun Biol. 2018 Sep 6;1:136. doi: 10.1038/s42003-018-0139-y. eCollection 2018.

23.

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Lim HY, Lim SY, Tan CK, Thiam CH, Goh CC, Carbajo D, Chew SHS, See P, Chakarov S, Wang XN, Lim LH, Johnson LA, Lum J, Fong CY, Bongso A, Biswas A, Goh C, Evrard M, Yeo KP, Basu R, Wang JK, Tan Y, Jain R, Tikoo S, Choong C, Weninger W, Poidinger M, Stanley RE, Collin M, Tan NS, Ng LG, Jackson DG, Ginhoux F, Angeli V.

Immunity. 2018 Aug 21;49(2):326-341.e7. doi: 10.1016/j.immuni.2018.06.008. Epub 2018 Jul 24. Erratum in: Immunity. 2018 Dec 18;49(6):1191.

PMID:
30054204
24.

Anti-Allergic Inflammatory Activity of Interleukin-37 Is Mediated by Novel Signaling Cascades in Human Eosinophils.

Zhu J, Dong J, Ji L, Jiang P, Leung TF, Liu D, Ng LG, Tsang MS, Jiao D, Lam CW, Wong CK.

Front Immunol. 2018 Jun 22;9:1445. doi: 10.3389/fimmu.2018.01445. eCollection 2018.

25.

Reverse-engineering flow-cytometry gating strategies for phenotypic labelling and high-performance cell sorting.

Becht E, Simoni Y, Coustan-Smith E, Evrard M, Cheng Y, Ng LG, Campana D, Newell EW.

Bioinformatics. 2019 Jan 15;35(2):301-308. doi: 10.1093/bioinformatics/bty491.

PMID:
29931307
26.

Intermediate Outcomes of Image-Guided Radiofrequency Ablation of Renal Tumours.

Chua JM, Rasheed S, Gogna A, Yuen JS, Lo RH, Ng LG, Chong TW, Irani FG, Too CW, Tan BS.

Ann Acad Med Singapore. 2018 Mar;47(3):119-122. No abstract available.

27.

Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging.

Feng G, Mao D, Liu J, Goh CC, Ng LG, Kong D, Tang BZ, Liu B.

Nanoscale. 2018 Mar 29;10(13):5869-5874. doi: 10.1039/C7NR09196F.

PMID:
29560485
28.

The impact of ischemia-reperfusion injuries on skin resident murine dendritic cells.

Goh CC, Evrard M, Chong SZ, Tan Y, Tan LL, Teng KWW, Weninger W, Becker DL, Tey HL, Newell EW, Liu B, Ng LG.

Eur J Immunol. 2018 Jun;48(6):1014-1019. doi: 10.1002/eji.201747347. Epub 2018 Mar 23.

29.

Nanostring Analysis of Skin Biopsies from Patients with Henoch-Schönlein Purpura Reveals Genes Associated with Pathology and Heterogeneity in the Disease Process.

Tan Y, Li JLY, Lee BTK, Lum J, Pramono ZAD, Evrard M, Poidinger M, Tey HL, Ng LG.

Acta Derm Venereol. 2018 Oct 10;98(9):896-897. doi: 10.2340/00015555-2914. No abstract available.

30.

Imaging of Inflammatory Responses in the Mouse Ear Skin.

Li JL, Goh CC, Ng LG.

Methods Mol Biol. 2018;1763:87-107. doi: 10.1007/978-1-4939-7762-8_9.

PMID:
29476491
31.

Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions.

Evrard M, Kwok IWH, Chong SZ, Teng KWW, Becht E, Chen J, Sieow JL, Penny HL, Ching GC, Devi S, Adrover JM, Li JLY, Liong KH, Tan L, Poon Z, Foo S, Chua JW, Su IH, Balabanian K, Bachelerie F, Biswas SK, Larbi A, Hwang WYK, Madan V, Koeffler HP, Wong SC, Newell EW, Hidalgo A, Ginhoux F, Ng LG.

Immunity. 2018 Feb 20;48(2):364-379.e8. doi: 10.1016/j.immuni.2018.02.002.

32.

Botulinum toxin and benign prostatic hyperplasia.

Ng LG.

Asian J Urol. 2018 Jan;5(1):33-36. doi: 10.1016/j.ajur.2017.11.003. Epub 2017 Nov 22. Review.

33.

Illuminating the covert mission of mononuclear phagocytes in their regional niches.

Chong SZ, Evrard M, Goh CC, Ng LG.

Curr Opin Immunol. 2018 Feb;50:94-101. doi: 10.1016/j.coi.2017.12.004. Epub 2017 Dec 21. Review.

PMID:
29275187
34.

A 3D Printed Implantable Device for Voiding the Bladder Using Shape Memory Alloy (SMA) Actuators.

Hassani FA, Peh WYX, Gammad GGL, Mogan RP, Ng TK, Kuo TLC, Ng LG, Luu P, Yen SC, Lee C.

Adv Sci (Weinh). 2017 Jul 26;4(11):1700143. doi: 10.1002/advs.201700143. eCollection 2017 Nov.

35.

Dual modal ultra-bright nanodots with aggregation-induced emission and gadolinium-chelation for vascular integrity and leakage detection.

Feng G, Li JLY, Claser C, Balachander A, Tan Y, Goh CC, Kwok IWH, Rénia L, Tang BZ, Ng LG, Liu B.

Biomaterials. 2018 Jan;152:77-85. doi: 10.1016/j.biomaterials.2017.10.031. Epub 2017 Oct 20.

PMID:
29111495
36.

A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment.

Sierro F, Evrard M, Rizzetto S, Melino M, Mitchell AJ, Florido M, Beattie L, Walters SB, Tay SS, Lu B, Holz LE, Roediger B, Wong YC, Warren A, Ritchie W, McGuffog C, Weninger W, Le Couteur DG, Ginhoux F, Britton WJ, Heath WR, Saunders BM, McCaughan GW, Luciani F, MacDonald KPA, Ng LG, Bowen DG, Bertolino P.

Immunity. 2017 Aug 15;47(2):374-388.e6. doi: 10.1016/j.immuni.2017.07.018.

37.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Takata K, Kozaki T, Lee CZW, Thion MS, Otsuka M, Lim S, Utami KH, Fidan K, Park DS, Malleret B, Chakarov S, See P, Low D, Low G, Garcia-Miralles M, Zeng R, Zhang J, Goh CC, Gul A, Hubert S, Lee B, Chen J, Low I, Shadan NB, Lum J, Wei TS, Mok E, Kawanishi S, Kitamura Y, Larbi A, Poidinger M, Renia L, Ng LG, Wolf Y, Jung S, Önder T, Newell E, Huber T, Ashihara E, Garel S, Pouladi MA, Ginhoux F.

Immunity. 2017 Jul 18;47(1):183-198.e6. doi: 10.1016/j.immuni.2017.06.017.

38.

Intravital multiphoton imaging of mouse tibialis anterior muscle.

Lau J, Goh CC, Devi S, Keeble J, See P, Ginhoux F, Ng LG.

Intravital. 2016 Apr 8;5(2):e1156272. doi: 10.1080/21659087.2016.1156272. eCollection 2016.

39.

Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2.

Ler LD, Ghosh S, Chai X, Thike AA, Heng HL, Siew EY, Dey S, Koh LK, Lim JQ, Lim WK, Myint SS, Loh JL, Ong P, Sam XX, Huang D, Lim T, Tan PH, Nagarajan S, Cheng CW, Ho H, Ng LG, Yuen J, Lin PH, Chuang CK, Chang YH, Weng WH, Rozen SG, Tan P, Creasy CL, Pang ST, McCabe MT, Poon SL, Teh BT.

Sci Transl Med. 2017 Feb 22;9(378). pii: eaai8312. doi: 10.1126/scitranslmed.aai8312.

PMID:
28228601
40.

Inducing Ischemia-reperfusion Injury in the Mouse Ear Skin for Intravital Multiphoton Imaging of Immune Responses.

Goh CC, Li JL, Becker D, Weninger W, Angeli V, Ng LG.

J Vis Exp. 2016 Dec 22;(118). doi: 10.3791/54956.

41.

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.

Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Duchene J, Lum J, Poidinger M, Chen Q, Rénia L, Wang CI, Larbi A, Randolph GJ, Weninger W, Looney MR, Krummel MF, Biswas SK, Ginhoux F, Hidalgo A, Bachelerie F, Ng LG.

J Exp Med. 2016 Oct 17;213(11):2293-2314. Epub 2016 Oct 10.

42.

Nanocrystallization: A Unique Approach to Yield Bright Organic Nanocrystals for Biological Applications.

Fateminia SM, Wang Z, Goh CC, Manghnani PN, Wu W, Mao D, Ng LG, Zhao Z, Tang BZ, Liu B.

Adv Mater. 2017 Jan;29(1). doi: 10.1002/adma.201604100. Epub 2016 Nov 2.

PMID:
27805762
43.

Tumor size and Fuhrman grade further enhance the prognostic impact of perinephric fat invasion and renal vein extension in T3a staging of renal cell carcinoma.

Chen K, Lee BL, Huang HH, Tan BY, Lee LS, Ng LG, Lau W, Yuen JS.

Int J Urol. 2017 Jan;24(1):51-58. doi: 10.1111/iju.13237. Epub 2016 Oct 18.

44.

Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains.

Ariyasu S, Too PC, Mu J, Goh CC, Ding Y, Tnay YL, Yeow EK, Yang L, Ng LG, Chiba S, Xing B.

Chem Commun (Camb). 2016 Mar 28;52(25):4667-70. doi: 10.1039/c5cc10230h.

PMID:
26953360
45.

Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation through CXCL2.

Li JL, Lim CH, Tay FW, Goh CC, Devi S, Malleret B, Lee B, Bakocevic N, Chong SZ, Evrard M, Tanizaki H, Lim HY, Russell B, Renia L, Zolezzi F, Poidinger M, Angeli V, St John AL, Harris JE, Tey HL, Tan SM, Kabashima K, Weninger W, Larbi A, Ng LG.

J Invest Dermatol. 2016 Feb;136(2):416-424. doi: 10.1038/JID.2015.410.

46.

Metformin Use in Relation With Survival Outcomes of Patients With Renal Cell Carcinoma.

Cheng JJ, Li H, Tan HS, Tan PH, Ng LG, Ng QS, Toh CK, Kanesvaran R, Tan MH.

Clin Genitourin Cancer. 2016 Apr;14(2):168-75. doi: 10.1016/j.clgc.2015.12.012. Epub 2015 Dec 21.

PMID:
26794391
47.

The clinical presentation and diagnosis of ketamine-associated urinary tract dysfunction in Singapore.

Yek J, Sundaram P, Aydin H, Kuo T, Ng LG.

Singapore Med J. 2015 Dec;56(12):660-4; quiz 665. doi: 10.11622/smedj.2015185.

48.

Identification of a novel lymphoid population in the murine epidermis.

Almeida FF, Tenno M, Brzostek J, Li JL, Allies G, Hoeffel G, See P, Ng LG, Fehling HJ, Gascoigne NR, Taniuchi I, Ginhoux F.

Sci Rep. 2015 Jul 30;5:12554. doi: 10.1038/srep12554.

49.

Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging.

Geng J, Goh CC, Qin W, Liu R, Tomczak N, Ng LG, Tang BZ, Liu B.

Chem Commun (Camb). 2015 Sep 7;51(69):13416-9. doi: 10.1039/c5cc03603h.

PMID:
26213866
50.

Biocompatible Green and Red Fluorescent Organic Dots with Remarkably Large Two-Photon Action Cross Sections for Targeted Cellular Imaging and Real-Time Intravital Blood Vascular Visualization.

Xiang J, Cai X, Lou X, Feng G, Min X, Luo W, He B, Goh CC, Ng LG, Zhou J, Zhao Z, Liu B, Tang BZ.

ACS Appl Mater Interfaces. 2015 Jul 15;7(27):14965-74. doi: 10.1021/acsami.5b03766. Epub 2015 Jul 2.

PMID:
26094687

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