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Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches.

Lim XF, Lee CB, Pascoe SM, How CB, Chan S, Tan JH, Yang X, Zhou P, Shi Z, Sessions OM, Wang LF, Ng LC, Anderson DE, Yap G.

J Gen Virol. 2019 Aug 16. doi: 10.1099/jgv.0.001307. [Epub ahead of print]


The applications of metabolomics in the molecular diagnostics of cancer.

Cheung PK, Ma MH, Tse HF, Yeung KF, Tsang HF, Chu MKM, Kan CM, Cho WCS, Ng LBW, Chan LWC, Wong SCC.

Expert Rev Mol Diagn. 2019 Aug 15. doi: 10.1080/14737159.2019.1656530. [Epub ahead of print]


Combined use of trimethylamine N-oxide with BNP for risk stratification in heart failure with preserved ejection fraction: findings from the DIAMONDHFpEF study.

Salzano A, Israr MZ, Yazaki Y, Heaney LM, Kanagala P, Singh A, Arnold JR, Gulsin GS, Squire IB, McCann GP, Ng LL, Suzuki T.

Eur J Prev Cardiol. 2019 Aug 14:2047487319870355. doi: 10.1177/2047487319870355. [Epub ahead of print] No abstract available.


Left atrial ejection fraction and outcomes in heart failure with preserved ejection fraction.

Kanagala P, Arnold JR, Cheng ASH, Singh A, Khan JN, Gulsin GS, Yang J, Zhao L, Gupta P, Squire IB, Ng LL, McCann GP.

Int J Cardiovasc Imaging. 2019 Aug 10. doi: 10.1007/s10554-019-01684-9. [Epub ahead of print]


People With COPD Who Respond to Ground-Based Walking Training Are Characterized by Lower Pre-training Exercise Capacity and Better Lung Function and Have Greater Progression in Walking Training Distance.

Ho JP, Alison JA, Ng LWC, Wootton SL, McKeough ZJ, Jenkins SC, Eastwood PR, Hillman DR, Jenkins C, Spencer LM, Cavalheri V, Hill K.

J Cardiopulm Rehabil Prev. 2019 Aug 6. doi: 10.1097/HCR.0000000000000421. [Epub ahead of print]


WNT Signaling in Disease.

Ng LF, Kaur P, Bunnag N, Suresh J, Sung ICH, Tan QH, Gruber J, Tolwinski NS.

Cells. 2019 Aug 3;8(8). pii: E826. doi: 10.3390/cells8080826. Review.


Pre-vaccination screening strategies for the use of the CYD-TDV dengue vaccine: A meeting report.

Wilder-Smith A, Smith PG, Luo R, Kelly-Cirino C, Curry D, Larson H, Durbin A, Chu M, Tharmaphornpilas P, Ng LC, Sartori AMC, Luna EJA, Gubler DJ, España G, Yoon IK, Flasche S.

Vaccine. 2019 Aug 23;37(36):5137-5146. doi: 10.1016/j.vaccine.2019.07.016. Epub 2019 Jul 31.


Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients.

Amrun SN, Yee WX, Abu Bakar F, Lee B, Kam YW, Lum FM, Tan JJ, Lim VW, Watthanaworawit W, Ling C, Nosten F, Renia L, Leo YS, Ng LF.

Clin Transl Immunology. 2019 Jul 26;8(7):e1066. doi: 10.1002/cti2.1066. eCollection 2019.


Geographical location affects the levels and association of trimethylamine N-oxide with heart failure mortality in BIOSTAT-CHF: a post-hoc analysis.

Yazaki Y, Salzano A, Nelson CP, Voors AA, Anker SD, Cleland JG, Lang CC, Metra M, Samani NJ, Ng LL, Suzuki T.

Eur J Heart Fail. 2019 Jul 28. doi: 10.1002/ejhf.1550. [Epub ahead of print] No abstract available.


Overexpression of Pin1 and rho signaling partners correlates with metastatic behavior and poor recurrence-free survival of hepatocellular carcinoma patients.

Ng L, Kwan V, Chow A, Yau TC, Poon RT, Pang R, Law WL.

BMC Cancer. 2019 Jul 19;19(1):713. doi: 10.1186/s12885-019-5919-3.


Opening TRPP2 (PKD2L1) requires the transfer of gating charges.

Ng LCT, Vien TN, Yarov-Yarovoy V, DeCaen PG.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15540-15549. doi: 10.1073/pnas.1902917116. Epub 2019 Jul 17.


Differential left ventricular and left atrial remodelling in heart failure with preserved ejection fraction patients with and without diabetes.

Gulsin GS, Kanagala P, Chan DCS, Cheng ASH, Athithan L, Graham-Brown MPM, Singh A, Yang J, Li Z, Khunti K, Davies MJ, Arnold JR, Squire IB, Ng LL, McCann GP.

Ther Adv Endocrinol Metab. 2019 Jul 5;10:2042018819861593. doi: 10.1177/2042018819861593. eCollection 2019.


Microdosing psychedelics: More questions than answers? An overview and suggestions for future research.

Kuypers KP, Ng L, Erritzoe D, Knudsen GM, Nichols CD, Nichols DE, Pani L, Soula A, Nutt D.

J Psychopharmacol. 2019 Jul 14:269881119857204. doi: 10.1177/0269881119857204. [Epub ahead of print]


Multi-modal image cytometry approach - From dynamic to whole organ imaging.

Husna N, Gascoigne NRJ, Tey HL, Ng LG, Tan Y.

Cell Immunol. 2019 Jul 2:103946. doi: 10.1016/j.cellimm.2019.103946. [Epub ahead of print]


Second WIN International Conference on "Integrated approaches and innovative tools for combating insecticide resistance in vectors of arboviruses", October 2018, Singapore.

Corbel V, Durot C, Achee NL, Chandre F, Coulibaly MB, David JP, Devine GJ, Dusfour I, Fonseca DM, Griego J, Juntarajumnong W, Lenhart A, Kasai S, Martins AJ, Moyes C, Ng LC, Pinto J, Pompon JF, Muller P, Raghavendra K, Roiz D, Vatandoost H, Vontas J, Weetman D.

Parasit Vectors. 2019 Jul 3;12(1):331. doi: 10.1186/s13071-019-3591-8.


Dengue virus-elicited tryptase induces endothelial permeability and shock.

Rathore AP, Mantri CK, Aman SA, Syenina A, Ooi J, Jagaraj CJ, Goh CC, Tissera H, Wilder-Smith A, Ng LG, Gubler DJ, St John AL.

J Clin Invest. 2019 Jul 2;130. pii: 128426. doi: 10.1172/JCI128426.


The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure.

Santema BT, Chan MMY, Tromp J, Dokter M, van der Wal HH, Emmens JE, Takens J, Samani NJ, Ng LL, Lang CC, van der Meer P, Ter Maaten JM, Damman K, Dickstein K, Cleland JG, Zannad F, Anker SD, Metra M, van der Harst P, de Boer RA, van Veldhuisen DJ, Rienstra M, Lam CSP, Voors AA.

Clin Res Cardiol. 2019 Jul 1. doi: 10.1007/s00392-019-01513-y. [Epub ahead of print]


Granulopoiesis and Neutrophil Homeostasis: A Metabolic, Daily Balancing Act.

Yvan-Charvet L, Ng LG.

Trends Immunol. 2019 Jul;40(7):598-612. doi: 10.1016/ Review.


One hypervirulent clone, sequence type 283, accounts for a large proportion of invasive Streptococcus agalactiae isolated from humans and diseased tilapia in Southeast Asia.

Barkham T, Zadoks RN, Azmai MNA, Baker S, Bich VTN, Chalker V, Chau ML, Dance D, Deepak RN, van Doorn HR, Gutierrez RA, Holmes MA, Huong LNP, Koh TH, Martins E, Mehershahi K, Newton P, Ng LC, Phuoc NN, Sangwichian O, Sawatwong P, Surin U, Tan TY, Tang WY, Thuy NV, Turner P, Vongsouvath M, Zhang D, Whistler T, Chen SL.

PLoS Negl Trop Dis. 2019 Jun 27;13(6):e0007421. doi: 10.1371/journal.pntd.0007421. eCollection 2019 Jun.


Interaction between Antibiotic Resistance, Resistance Genes and Treatment Response for Urinary Tract Infections in Primary Care.

Ho HJ, Tan MX, Chen MI, Tan TY, Koo SH, Koong AYL, Ng LP, Hu PL, Tan KT, Moey PKS, Koh EYL, Wong CS, Lye DC, Tan NC.

J Clin Microbiol. 2019 Jun 26. pii: JCM.00143-19. doi: 10.1128/JCM.00143-19. [Epub ahead of print]


The effectiveness of inspections on reported mosquito larval habitats in households: A case-control study.

Aik J, Neo ZW, Rajarethinam J, Chio K, Lam WM, Ng LC.

PLoS Negl Trop Dis. 2019 Jun 26;13(6):e0007492. doi: 10.1371/journal.pntd.0007492. eCollection 2019 Jun.


Documenting psychiatric risk: more than ticking boxes.

Ng L, Zeng I, Kalinowski C, Watson P.

Australas Psychiatry. 2019 Jun 26:1039856219859272. doi: 10.1177/1039856219859272. [Epub ahead of print]


Association of systemic lupus erythematosus (SLE) genetic susceptibility loci with lupus nephritis in childhood-onset and adult-onset SLE.

Webber D, Cao J, Dominguez D, Gladman DD, Levy DM, Ng L, Paterson AD, Touma Z, Urowitz MB, Wither JE, Silverman ED, Hiraki LT.

Rheumatology (Oxford). 2019 Jun 24. pii: kez220. doi: 10.1093/rheumatology/kez220. [Epub ahead of print]


PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.

Bianchini M, Duchêne J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA.

Sci Immunol. 2019 Jun 21;4(36). pii: eaar3054. doi: 10.1126/sciimmunol.aar3054.


Locating "gold standard" evidence for simulation as a substitute for clinical practice in prelicensure health professional education: A systematic review.

Bogossian FE, Cant RP, Ballard EL, Cooper SJ, Levett-Jones TL, McKenna LG, Ng LC, Seaton PC.

J Clin Nurs. 2019 Jun 19. doi: 10.1111/jocn.14965. [Epub ahead of print] Review.


Inferring who-infected-whom-where in the 2016 Zika outbreak in Singapore-a spatio-temporal model.

Prem K, Lau MSY, Tam CC, Ho MZJ, Ng LC, Cook AR.

J R Soc Interface. 2019 Jun 28;16(155):20180604. doi: 10.1098/rsif.2018.0604. Epub 2019 Jun 19.


Inhibition of amyloid-induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model.

Cheah IK, Ng LT, Ng LF, Lam VY, Gruber J, Huang CYW, Goh FQ, Lim KHC, Halliwell B.

FEBS Lett. 2019 Jun 18. doi: 10.1002/1873-3468.13497. [Epub ahead of print]


Classification of electrophysiological and morphological neuron types in the mouse visual cortex.

Gouwens NW, Sorensen SA, Berg J, Lee C, Jarsky T, Ting J, Sunkin SM, Feng D, Anastassiou CA, Barkan E, Bickley K, Blesie N, Braun T, Brouner K, Budzillo A, Caldejon S, Casper T, Castelli D, Chong P, Crichton K, Cuhaciyan C, Daigle TL, Dalley R, Dee N, Desta T, Ding SL, Dingman S, Doperalski A, Dotson N, Egdorf T, Fisher M, de Frates RA, Garren E, Garwood M, Gary A, Gaudreault N, Godfrey K, Gorham M, Gu H, Habel C, Hadley K, Harrington J, Harris JA, Henry A, Hill D, Josephsen S, Kebede S, Kim L, Kroll M, Lee B, Lemon T, Link KE, Liu X, Long B, Mann R, McGraw M, Mihalas S, Mukora A, Murphy GJ, Ng L, Ngo K, Nguyen TN, Nicovich PR, Oldre A, Park D, Parry S, Perkins J, Potekhina L, Reid D, Robertson M, Sandman D, Schroedter M, Slaughterbeck C, Soler-Llavina G, Sulc J, Szafer A, Tasic B, Taskin N, Teeter C, Thatra N, Tung H, Wakeman W, Williams G, Young R, Zhou Z, Farrell C, Peng H, Hawrylycz MJ, Lein E, Ng L, Arkhipov A, Bernard A, Phillips JW, Zeng H, Koch C.

Nat Neurosci. 2019 Jul;22(7):1182-1195. doi: 10.1038/s41593-019-0417-0. Epub 2019 Jun 17.


A comparison of electronic and paper-based clinical skills assessment: Systematic review.

Phillips AC, Mackintosh SF, Gibbs C, Ng L, Fryer CE.

Med Teach. 2019 Jun 16:1-9. doi: 10.1080/0142159X.2019.1623387. [Epub ahead of print]


Vaginal laceration during barium enema with extraperitoneal extravasation: Case report and literature review.

Towers GD, Ng L, Maxwell RA, Madison S, Yaklic JL.

Radiol Case Rep. 2019 May 9;14(7):851-857. doi: 10.1016/j.radcr.2019.04.017. eCollection 2019 Jul.


Appreciative Inquiry in Psychiatry Peer Groups.

Ng L, Bampton C, Kautoke S, Cheung G.

Acad Psychiatry. 2019 Jun 12. doi: 10.1007/s40596-019-01078-y. [Epub ahead of print]


Chikungunya virus drug discovery: still a long way to go?

Pérez-Pérez MJ, Delang L, Ng LFP, Priego EM.

Expert Opin Drug Discov. 2019 Sep;14(9):855-866. doi: 10.1080/17460441.2019.1629413. Epub 2019 Jun 14.


The Seow Operative Score (SOS) as a decision-making adjunct for paediatric Chiari I malformation: a preliminary study.

Low SYY, Ng LP, Tan AJL, Low DCY, Seow WT.

Childs Nerv Syst. 2019 Jun 7. doi: 10.1007/s00381-019-04226-9. [Epub ahead of print]


Social support network typologies and their association with dementia and depression among older adults in Singapore: a cross-sectional analysis.

Lau YW, Vaingankar JA, Abdin E, Shafie S, Jeyagurunathan A, Zhang Y, Magadi H, Ng LL, Chong SA, Subramaniam M.

BMJ Open. 2019 Jun 1;9(5):e025303. doi: 10.1136/bmjopen-2018-025303.


Prevalence and antibiotic susceptibility of colistin-resistance gene (mcr-1) positive Enterobacteriaceae in stool specimens of patients attending a tertiary care hospital in Singapore.

La MV, Lee B, Hong BZM, Yah JY, Koo SH, Jiang B, Ng LSY, Tan TY.

Int J Infect Dis. 2019 Aug;85:124-126. doi: 10.1016/j.ijid.2019.05.029. Epub 2019 May 30.


The Difference in Lower Limb Landing Kinematics Between Adolescent Dancers and Non-Dancers.

Hendry D, Campbell A, Ng L, Harwood A, Wild C.

J Dance Med Sci. 2019 Jun 15;23(2):72-79. doi: 10.12678/1089-313X.23.2.72.


Serological evidence of continued Japanese encephalitis virus transmission in Singapore nearly three decades after end of pig farming.

Yap G, Lim XF, Chan S, How CB, Humaidi M, Yeo G, Mailepessov D, Kong M, Lai YL, Okumura C, Ng LC.

Parasit Vectors. 2019 May 17;12(1):244. doi: 10.1186/s13071-019-3501-0.


The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemoresistance, EMT and cancer stemness in hepatocellular carcinoma.

Fung SW, Cheung PF, Yip CW, Ng LW, Cheung TT, Chong CC, Lee C, Lai PB, Chan AW, Tsao GS, Wong CH, Chan SL, Lo KW, Cheung ST.

Cancer Lett. 2019 Aug 10;457:98-109. doi: 10.1016/j.canlet.2019.05.010. Epub 2019 May 14.


Proenkephalin, an Opioid System Surrogate, as a Novel Comprehensive Renal Marker in Heart Failure.

Emmens JE, Ter Maaten JM, Damman K, van Veldhuisen DJ, de Boer RA, Struck J, Bergmann A, Sama IE, Streng KW, Anker SD, Dickstein K, Lang CC, Metra M, Samani NJ, Ng LL, Voors AA.

Circ Heart Fail. 2019 May;12(5):e005544. doi: 10.1161/CIRCHEARTFAILURE.118.005544.


The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study.

Markousis-Mavrogenis G, Tromp J, Ouwerkerk W, Devalaraja M, Anker SD, Cleland JG, Dickstein K, Filippatos GS, van der Harst P, Lang CC, Metra M, Ng LL, Ponikowski P, Samani NJ, Zannad F, Zwinderman AH, Hillege HL, van Veldhuisen DJ, Kakkar R, Voors AA, van der Meer P.

Eur J Heart Fail. 2019 Aug;21(8):965-973. doi: 10.1002/ejhf.1482. Epub 2019 May 14.


Balancing Energy and IAQ: NIST Net-Zero Energy Residential Test Facility.

Ng L, Poppendieck D, Dols WS, Dougherty BP, Emmerich SJ.

ASHRAE J. 2018 Apr;60(4). pii: D-AJ18Apr01. No abstract available.


Force-of-infection and True Infection Rate of Dengue in Singapore - its implication on dengue control and management.

Tan LK, Low SL, Sun H, Shi Y, Liu L, Lam S, Tan HH, Ang LW, Wong WY, Chua R, Teo D, Ng LC, Cook AR.

Am J Epidemiol. 2019 May 7. pii: kwz110. doi: 10.1093/aje/kwz110. [Epub ahead of print]


Capturing the Fantastic Voyage of Monocytes Through Time and Space.

Teh YC, Ding JL, Ng LG, Chong SZ.

Front Immunol. 2019 Apr 16;10:834. doi: 10.3389/fimmu.2019.00834. eCollection 2019. Review.


Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan.

Ng LF, Ng LT, van Breugel M, Halliwell B, Gruber J.

Front Genet. 2019 Apr 12;10:311. doi: 10.3389/fgene.2019.00311. eCollection 2019.


Application of a targeted-enrichment methodology for full-genome sequencing of Dengue 1-4, Chikungunya and Zika viruses directly from patient samples.

Kamaraj US, Tan JH, Xin Mei O, Pan L, Chawla T, Uehara A, Wang LF, Ooi EE, Gubler DJ, Tissera H, Ng LC, Wilder-Smith A, de Sessions PF, Barkham T, Anderson DE, Sessions OM.

PLoS Negl Trop Dis. 2019 Apr 25;13(4):e0007184. doi: 10.1371/journal.pntd.0007184. eCollection 2019 Apr.


Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate.

Chan YH, Teo TH, Utt A, Tan JJ, Amrun SN, Abu Bakar F, Yee WX, Becht E, Lee CY, Lee B, Rajarethinam R, Newell E, Merits A, Carissimo G, Lum FM, Ng LF.

EMBO Mol Med. 2019 Jun;11(6). pii: e10092. doi: 10.15252/emmm.201810092.


"Cloaking" on Time: A Cover-Up Act by Resident Tissue Macrophages.

Blériot C, Ng LG, Ginhoux F.

Cell. 2019 Apr 18;177(3):514-516. doi: 10.1016/j.cell.2019.03.042.


Effects of Ongoing Feedback During a 12-Month Maintenance Walking Program on Daily Physical Activity in People with COPD.

Wootton SL, Hill K, Alison JA, Ng LWC, Jenkins S, Eastwood PR, Hillman DR, Jenkins C, Spencer LM, Cecins N, McKeough ZJ.

Lung. 2019 Jun;197(3):315-319. doi: 10.1007/s00408-019-00216-5. Epub 2019 Apr 15.


Augmented Adsorptive Blood Purification during Continuous Veno-Venous Haemodiafiltration in a Severe Septic, Acute Kidney Injury Patient: Use of oXiris®: A Single Centre Case Report.

Tan HK, Kaushik M, Tan CW, Liew ZH, Teo SH, Loo CM, Ng LC, Choong LHL, Foo MWY.

Blood Purif. 2019;47 Suppl 3:1-6. doi: 10.1159/000499633. Epub 2019 Apr 12.


A germline variant of TP53 in paediatric diffuse leptomeningeal glioneuronal tumour.

Tan GIL, Merchant K, Tan EEK, Low DCY, Ng LP, Seow WT, Low SYY.

Childs Nerv Syst. 2019 Jun;35(6):1021-1027. doi: 10.1007/s00381-019-04128-w. Epub 2019 Apr 2.


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