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Utility of a standardized training program for endoscopic diagnosis of early gastrointestinal neoplasia.

Chiu PW, Sano Y, Uedo N, Singh R, Ng EKW, Aang TL, Chiu HM, Ho SH, Banerjee R, Tanaka S, Li XB, Yao F, Lau JYW, Yao K.

Endosc Int Open. 2019 Apr;7(4):E452-E458. doi: 10.1055/a-0854-3525. Epub 2019 Mar 21.


Per oral endoscopic tumor (POET) resection for treatment of upper gastrointestinal subepithelial tumors.

Chiu PWY, Yip HC, Teoh AYB, Wong VWY, Chan SM, Wong SKH, Ng EKW.

Surg Endosc. 2019 Apr;33(4):1326-1333. doi: 10.1007/s00464-018-06627-4. Epub 2019 Jan 2.


How I do it: Flexible 3-D endoscope for endoscopic submucosal dissection.

Chiu PWY, Yip HC, Xia XF, Chan SM, Ng EKW, Lau JYW.

Dig Endosc. 2019 May;31(3):323-328. doi: 10.1111/den.13315. Epub 2019 Mar 21.


An Asian consensus on standards of diagnostic upper endoscopy for neoplasia.

Chiu PWY, Uedo N, Singh R, Gotoda T, Ng EKW, Yao K, Ang TL, Ho SH, Kikuchi D, Yao F, Pittayanon R, Goda K, Lau JYW, Tajiri H, Inoue H.

Gut. 2019 Feb;68(2):186-197. doi: 10.1136/gutjnl-2018-317111. Epub 2018 Nov 12.


Portomesenteric vein thrombosis following laparoscopic greater curve plication for morbid obesity.

Lai CM, Liu SY, Wong JK, Wong SK, Ng EK.

Obes Res Clin Pract. 2018 Nov - Dec;12(6):578-582. doi: 10.1016/j.orcp.2018.10.001.


Validation of water-fat MRI and proton MRS in assessment of hepatic fat and the heterogeneous distribution of hepatic fat and iron in subjects with non-alcoholic fatty liver disease.

Hui SCN, So HK, Chan DFY, Wong SKH, Yeung DKW, Ng EKW, Chu WCW.

Eur J Radiol. 2018 Oct;107:7-13. doi: 10.1016/j.ejrad.2018.08.008. Epub 2018 Aug 11.


Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer.

Liu SS, Chan KKL, Chu DKH, Wei TN, Lau LSK, Ngu SF, Chu MMY, Tse KY, Ip PPC, Ng EKO, Cheung ANY, Ngan HYS.

Mol Oncol. 2018 Dec;12(12):2009-2022. doi: 10.1002/1878-0261.12383. Epub 2018 Sep 27.


Observed changes in brown, white, hepatic and pancreatic fat after bariatric surgery: Evaluation with MRI.

Hui SCN, Wong SKH, Ai Q, Yeung DKW, Ng EKW, Chu WCW.

Eur Radiol. 2019 Feb;29(2):849-856. doi: 10.1007/s00330-018-5611-z. Epub 2018 Jul 30.


CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.

Li W, Wong CC, Zhang X, Kang W, Nakatsu G, Zhao Q, Chen H, Go MYY, Chiu PWY, Wang X, Ji J, Li X, Cai Z, Ng EKW, Yu J.

Oncogene. 2018 Dec;37(50):6383-6398. doi: 10.1038/s41388-018-0402-1. Epub 2018 Jul 27.


MicroRNA-125b Interacts with Foxp3 to Induce Autophagy in Thyroid Cancer.

Wang S, Wu J, Ren J, Vlantis AC, Li MY, Liu SYW, Ng EKW, Chan ABW, Luo DC, Liu Z, Guo W, Xue L, Ng SK, van Hasselt CA, Tong MCF, Chen GG.

Mol Ther. 2018 Sep 5;26(9):2295-2303. doi: 10.1016/j.ymthe.2018.06.015. Epub 2018 Jun 21.


MiR-92 suppresses proliferation and induces apoptosis by targeting EP4/Notch1 axis in gastric cancer.

Shin VY, Siu MT, Liu X, Ng EKO, Kwong A, Chu KM.

Oncotarget. 2018 May 11;9(36):24209-24220. doi: 10.18632/oncotarget.24819. eCollection 2018 May 11.


Molecular alterations of cancer cell and tumour microenvironment in metastatic gastric cancer.

Li W, Ng JM, Wong CC, Ng EKW, Yu J.

Oncogene. 2018 Sep;37(36):4903-4920. doi: 10.1038/s41388-018-0341-x. Epub 2018 May 23. Review.


Global Incidence and mortality of oesophageal cancer and their correlation with socioeconomic indicators temporal patterns and trends in 41 countries.

Wong MCS, Hamilton W, Whiteman DC, Jiang JY, Qiao Y, Fung FDH, Wang HHX, Chiu PWY, Ng EKW, Wu JCY, Yu J, Chan FKL, Sung JJY.

Sci Rep. 2018 Mar 14;8(1):4522. doi: 10.1038/s41598-018-19819-8.


EUS-FNA using 22G nitinol or ProCore needles without on-site cytopathology.

Chong CCN, Teoh AYB, Tang RSY, Chan AWH, Ng EKW, Lai PBS.

Endosc Ultrasound. 2018 Jan-Feb;7(1):56-60. doi: 10.4103/eus.eus_113_17.


Serum microRNA-193b as a promising biomarker for prediction of chemoradiation sensitivity in esophageal squamous cell carcinoma patients.

Chan CM, Lai KKY, Ng EKO, Kiang MN, Kwok TWH, Wang HK, Chan KW, Law TT, Tong DK, Chan KT, Lee NP, Law S.

Oncol Lett. 2018 Mar;15(3):3273-3280. doi: 10.3892/ol.2017.7698. Epub 2017 Dec 27.


Knowledge and attitudes of Singapore schoolchildren learning cardiopulmonary resuscitation and automated external defibrillator skills.

Kua PHJ, White AE, Ng WY, Fook-Chong S, Ng EKX, Ng YY, Ong MEH.

Singapore Med J. 2018 Sep;59(9):487-499. doi: 10.11622/smedj.2018021. Epub 2018 Feb 12.


Na+ /H+ exchanger 3 blockade ameliorates type 2 diabetes mellitus via inhibition of sodium-glucose co-transporter 1-mediated glucose absorption in the small intestine.

Chan LKY, Wang Y, Ng EKW, Leung PS.

Diabetes Obes Metab. 2018 Mar;20(3):709-717. doi: 10.1111/dom.13151. Epub 2017 Dec 5.


Secretome from hypoxia-conditioned adipose-derived mesenchymal stem cells promotes the healing of gastric mucosal injury in a rodent model.

Xia X, Chiu PWY, Lam PK, Chin WC, Ng EKW, Lau JYW.

Biochim Biophys Acta Mol Basis Dis. 2018 Jan;1864(1):178-188. doi: 10.1016/j.bbadis.2017.10.009. Epub 2017 Oct 6.


Randomized controlled trial of EndoWrist-enabled robotic versus human laparoendoscopic single-site access surgery (LESS) in the porcine model.

Teoh AYB, Chan SM, Yip HC, Wong VWY, Chiu PWY, Ng EKW.

Surg Endosc. 2018 Mar;32(3):1273-1279. doi: 10.1007/s00464-017-5803-7. Epub 2017 Aug 11.


Robust and accurate digital measurement for HER2 amplification in HER2 equivocal breast cancer diagnosis.

Wang Y, Tsang JYS, Cui Y, Cui J, Lin Y, Zhao S, Law PTW, Cheung SY, Ng EKO, Tse GMK, Ke Z.

Sci Rep. 2017 Jul 28;7(1):6752. doi: 10.1038/s41598-017-07176-x.


Electroacupuncture-reduced sedative and analgesic requirements for diagnostic EUS: a prospective, randomized, double-blinded, sham-controlled study.

Teoh AYB, Chong CCN, Leung WW, Chan SKC, Tse YK, Ng EKW, Lai PBS, Wu JCY, Lau JYW.

Gastrointest Endosc. 2018 Feb;87(2):476-485. doi: 10.1016/j.gie.2017.07.029. Epub 2017 Jul 24.


Clinical pattern and prevalence of upper gastrointestinal toxicity in patients abusing ketamine.

Liu SYW, Ng SKK, Tam YH, Yee SCH, Lai FPT, Hong CYL, Chiu PWY, Ng EKW, Ng CF.

J Dig Dis. 2017 Sep;18(9):504-510. doi: 10.1111/1751-2980.12512.


Measuring the effectiveness of a novel CPRcard™ feedback device during simulated chest compressions by non-healthcare workers.

White AE, Ng HX, Ng WY, Ng EK, Fook-Chong S, Kua PH, Ong ME.

Singapore Med J. 2017 Jul;58(7):438-445. doi: 10.11622/smedj.2017072.


Circulating MicroRNA in patients with repaired tetralogy of Fallot.

Lai CTM, Ng EKO, Chow PC, Kwong A, Cheung YF.

Eur J Clin Invest. 2017 Aug;47(8):574-582. doi: 10.1111/eci.12778. Epub 2017 Jul 18.


Roux-en-Y or Billroth II Reconstruction After Radical Distal Gastrectomy for Gastric Cancer: A Multicenter Randomized Controlled Trial.

So JB, Rao J, Wong AS, Chan YH, Pang NQ, Tay AYL, Yung MY, Su Z, Phua JNS, Shabbir A, Ng EKW.

Ann Surg. 2018 Feb;267(2):236-242. doi: 10.1097/SLA.0000000000002229.


Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.

Qian Y, Wong CC, Xu J, Chen H, Zhang Y, Kang W, Wang H, Zhang L, Li W, Chu ESH, Go MYY, Chiu PWY, Ng EKW, Chan FKL, Sung JJY, Si J, Yu J.

Cancer Res. 2017 Apr 15;77(8):1968-1982. doi: 10.1158/0008-5472.CAN-16-1595. Epub 2017 Feb 15.


Removal of submucosal embedded fish bone in the esophagus with endoscopic submucosal dissection.

Yip HC, Chiu PW, Chan SM, Teoh AY, Ng EK.

VideoGIE. 2016 Dec 7;2(1):1. doi: 10.1016/j.vgie.2016.11.007. eCollection 2017 Jan. No abstract available.


Endoscopic ultrasound-guided gallbladder drainage reduces adverse events compared with percutaneous cholecystostomy in patients who are unfit for cholecystectomy.

Teoh AYB, Serna C, Penas I, Chong CCN, Perez-Miranda M, Ng EKW, Lau JYW.

Endoscopy. 2017 Feb;49(2):130-138. doi: 10.1055/s-0042-119036. Epub 2016 Nov 22.


Esophageal leakage after surgical repair of spontaneous rupture: successful closure with endoscopic suture device.

Yip HC, Chiu PW, Chan SM, Wong VW, Teoh AY, Wong SK, Ng EK.

Endoscopy. 2016 0;48(S 01):E344-E345. Epub 2016 Nov 16. No abstract available.


Robotic-assisted minimally invasive esophagectomy for treatment of esophageal carcinoma.

Chiu PW, Teoh AY, Wong VW, Yip HC, Chan SM, Wong SK, Ng EK.

J Robot Surg. 2017 Jun;11(2):193-199. doi: 10.1007/s11701-016-0644-2. Epub 2016 Oct 25.


Feasibility of per-oral cholecystoscopy and advanced gallbladder interventions after EUS-guided gallbladder stenting (with video).

Chan SM, Teoh AYB, Yip HC, Wong VWY, Chiu PWY, Ng EKW.

Gastrointest Endosc. 2017 Jun;85(6):1225-1232. doi: 10.1016/j.gie.2016.10.014. Epub 2016 Oct 15.


Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation-Long-term Results and Recurrence Rate.

Liu SY, Chu CC, Tsui TK, Wong SK, Kong AP, Chiu PW, Chow FC, Ng EK.

Radiology. 2016 Nov;281(2):625-634. Epub 2016 May 27.


An innovative ex-vivo porcine upper gastrointestinal model for submucosal tunnelling endoscopic resection (STER).

Yeung B, Chiu P, Teoh A, Zheng L, Chan S, Lam K, Tang R, Ng EK.

Endosc Int Open. 2016 Oct;4(10):E1101-E1106. Epub 2016 Sep 14.


Re: Colorectal endoscopic submucosal dissection at a low-volume centre.

Ng EK.

Hong Kong Med J. 2016 Oct;22(5):512. doi: 10.12809/hkmj164994. No abstract available.


Epigenetic silencing of the NR4A3 tumor suppressor, by aberrant JAK/STAT signaling, predicts prognosis in gastric cancer.

Yeh CM, Chang LY, Lin SH, Chou JL, Hsieh HY, Zeng LH, Chuang SY, Wang HW, Dittner C, Lin CY, Lin JM, Huang YT, Ng EK, Cheng AS, Wu SF, Lin J, Yeh KT, Chan MW.

Sci Rep. 2016 Aug 16;6:31690. doi: 10.1038/srep31690.


Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma.

Liu SY, Chu CM, Kong AP, Wong SK, Chiu PW, Chow FC, Ng EK.

Br J Surg. 2016 Oct;103(11):1476-86. doi: 10.1002/bjs.10219. Epub 2016 Aug 11.


Is Preoperative Upper Gastrointestinal Endoscopy in Obese Patients Undergoing Bariatric Surgery Mandatory? An Asian Perspective.

Lee J, Wong SK, Liu SY, Ng EK.

Obes Surg. 2017 Jan;27(1):44-50. doi: 10.1007/s11695-016-2243-8.


REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype.

Yu J, Liang Q, Wang J, Wang K, Gao J, Zhang J, Zeng Y, Chiu PW, Ng EK, Sung JJ.

Oncogene. 2017 Jan 12;36(2):182-193. doi: 10.1038/onc.2016.187. Epub 2016 May 23.


Robotic versus Open Thyroidectomy for Differentiated Thyroid Cancer: An Evidence-Based Review.

Liu SY, Ng EK.

Int J Endocrinol. 2016;2016:4309087. doi: 10.1155/2016/4309087. Epub 2016 Mar 16. Review.


Asian consensus on the relationship between obesity and gastrointestinal and liver diseases.

Koh JC, Loo WM, Goh KL, Sugano K, Chan WK, Chiu WY, Choi MG, Gonlachanvit S, Lee WJ, Lee WJ, Lee YY, Lesmana LA, Li YM, Liu CJ, Matsuura B, Nakajima A, Ng EK, Sollano JD, Wong SK, Wong VW, Yang Y, Ho KY, Dan YY.

J Gastroenterol Hepatol. 2016 Aug;31(8):1405-13. doi: 10.1111/jgh.13385. Review.


Expression of Antioxidant Molecules and Heat Shock Protein 27 in Thyroid Tumors.

Wang S, Yang S, Vlantis AC, Liu SY, Ng EK, Chan AB, Wu J, Du J, Wei W, Liu X, Liu Z, Ng SK, van Hasselt CA, Tong MC, Chen GG.

J Cell Biochem. 2016 Nov;117(11):2473-81. doi: 10.1002/jcb.25539. Epub 2016 Aug 16.


Correlation of CBD/CHD angulation with recurrent cholangitis in patients treated with ERCP.

Chong CC, Chiu PW, Tan T, Teoh AY, Lee KF, Ng EK, Lai PB, Lau JY.

Endosc Int Open. 2016 Jan;4(1):E62-7. doi: 10.1055/s-0035-1569689.


Ex vivo comparison of the lumen-apposing properties of EUS-specific stents (with video).

Teoh AY, Ng EK, Chan SM, Lai M, Moran S, Binmoeller KF, Moon JH, Ho KY.

Gastrointest Endosc. 2016 Jul;84(1):62-8. doi: 10.1016/j.gie.2015.11.041. Epub 2015 Dec 10.


A three-miRNA signature as promising non-invasive diagnostic marker for gastric cancer.

Shin VY, Ng EK, Chan VW, Kwong A, Chu KM.

Mol Cancer. 2015 Nov 25;14:202. doi: 10.1186/s12943-015-0473-3.


Epigenetic silencing of GDF1 disrupts SMAD signaling to reinforce gastric cancer development.

Yang W, Mok MT, Li MS, Kang W, Wang H, Chan AW, Chou JL, Chen J, Ng EK, To KF, Yu J, Chan MW, Chan FK, Sung JJ, Cheng AS.

Oncogene. 2016 Apr 21;35(16):2133-44. doi: 10.1038/onc.2015.276. Epub 2015 Jul 27.


MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome.

Wang K, Liang Q, Li X, Tsoi H, Zhang J, Wang H, Go MY, Chiu PW, Ng EK, Sung JJ, Yu J.

Gut. 2016 Oct;65(10):1619-31. doi: 10.1136/gutjnl-2015-309276. Epub 2015 Jul 23.


Health-Related Quality of Life after Bariatric Surgery and its Correlation with Glycaemic Status in Hong Kong Chinese Adults.

Wu E, Luk A, Wong SK, So WY, Kong A, Chow F, Zhang Y, Lam C, Ng EK.

Obes Surg. 2016 Mar;26(3):538-45. doi: 10.1007/s11695-015-1787-3.


Comparison of early outcomes and quality of life after laparoscopic Heller's cardiomyotomy to peroral endoscopic myotomy for treatment of achalasia.

Chan SM, Wu JC, Teoh AY, Yip HC, Ng EK, Lau JY, Chiu PW.

Dig Endosc. 2016 Jan;28(1):27-32. doi: 10.1111/den.12507. Epub 2015 Aug 11.


Circulating cell-free miRNAs as biomarker for triple-negative breast cancer.

Shin VY, Siu JM, Cheuk I, Ng EK, Kwong A.

Br J Cancer. 2015 May 26;112(11):1751-9. doi: 10.1038/bjc.2015.143. Epub 2015 Apr 23.


Long-term Results on Weight Loss and Diabetes Remission after Laparoscopic Sleeve Gastrectomy for A Morbidly Obese Chinese Population.

Liu SY, Wong SK, Lam CC, Yung MY, Kong AP, Ng EK.

Obes Surg. 2015 Oct;25(10):1901-8. doi: 10.1007/s11695-015-1628-4.


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