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Items: 1 to 50 of 72

1.

Developing a three-dimensional animation for deeper molecular understanding of michaelis-menten enzyme kinetics.

Florjanczyk U, Ng DP, Andreopoulos S, Jenkinson J.

Biochem Mol Biol Educ. 2018 Sep;46(5):561-565. doi: 10.1002/bmb.21168.

PMID:
30369036
2.

An Evaluation of a Factor Xa-Based Clotting Time Test for Enoxaparin: A Proof-of-Concept Study.

Ng DPJ, Duffull SB, Faed JM, Isbister GK, Gulati A.

Clin Appl Thromb Hemost. 2018 May;24(4):669-676. doi: 10.1177/1076029617711802. Epub 2017 Jul 21.

3.

Modulating Transmembrane α-Helix Interactions through pH-Sensitive Boundary Residues.

Ng DP, Deber CM.

Biochemistry. 2016 Aug 9;55(31):4306-15. doi: 10.1021/acs.biochem.6b00380. Epub 2016 Aug 1.

PMID:
27434090
4.

Computer-aided detection of rare tumor populations in flow cytometry: an example with classic Hodgkin lymphoma.

Ng DP, Wu D, Wood BL, Fromm JR.

Am J Clin Pathol. 2015 Sep;144(3):517-24. doi: 10.1309/AJCPY8E2LYHCGUFP.

PMID:
26276783
5.

Helix-helix interactions: is the medium the message?

Deber CM, Ng DP.

Structure. 2015 Mar 3;23(3):437-438. doi: 10.1016/j.str.2015.02.004.

6.

Terminal residue hydrophobicity modulates transmembrane helix-helix interactions.

Ng DP, Deber CM.

Biochemistry. 2014 Jun 17;53(23):3747-57. doi: 10.1021/bi500317h. Epub 2014 Jun 9.

PMID:
24857611
7.

Accurate fetal chromosome dosage determination by shotgun sequencing of maternal plasma DNA without PCR amplification during library preparation.

Jin S, Lim YC, Ng DP, Law HY, Kwek KY, Yeo GS, Ding C.

Clin Chem. 2014 Apr;60(4):690-2. doi: 10.1373/clinchem.2013.216838. Epub 2014 Feb 3. No abstract available.

8.

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese.

Ma RC, Lee HM, Lam VK, Tam CH, Ho JS, Zhao HL, Guan J, Kong AP, Lau E, Zhang G, Luk A, Wang Y, Tsui SK, Chan TF, Hu C, Jia WP, Park KS, Lee HK, Furuta H, Nanjo K, Tai ES, Ng DP, Tang NL, Woo J, Leung PC, Xue H, Wong J, Leung PS, Lau TC, Tong PC, Xu G, Ng MC, So WY, Chan JC.

PLoS One. 2014 Jan 20;9(1):e84770. doi: 10.1371/journal.pone.0084770. eCollection 2014.

9.

Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples.

Lee YK, Jin S, Duan S, Lim YC, Ng DP, Lin XM, Yeo GS, Ding C.

Biol Proced Online. 2014 Jan 9;16(1):1. doi: 10.1186/1480-9222-16-1.

10.

Short-term preoperative diet modification reduces steatosis and blood loss in patients undergoing liver resection.

Reeves JG, Suriawinata AA, Ng DP, Holubar SD, Mills JB, Barth RJ Jr.

Surgery. 2013 Nov;154(5):1031-7. doi: 10.1016/j.surg.2013.04.012. Epub 2013 Jun 27.

PMID:
23809869
11.

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations.

Lam VK, Ma RC, Lee HM, Hu C, Park KS, Furuta H, Wang Y, Tam CH, Sim X, Ng DP, Liu J, Wong TY, Tai ES, Morris AP; DIAGRAM Consortium, Tang NL, Woo J, Leung PC, Kong AP, Ozaki R, Jia WP, Lee HK, Nanjo K, Xu G, Ng MC, So WY, Chan JC.

PLoS One. 2013 Jun 11;8(6):e62378. doi: 10.1371/journal.pone.0062378. Print 2013.

12.

Global DNA hypermethylation in down syndrome placenta.

Jin S, Lee YK, Lim YC, Zheng Z, Lin XM, Ng DP, Holbrook JD, Law HY, Kwek KY, Yeo GS, Ding C.

PLoS Genet. 2013 Jun;9(6):e1003515. doi: 10.1371/journal.pgen.1003515. Epub 2013 Jun 6.

13.

Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.

Ma RC, Hu C, Tam CH, Zhang R, Kwan P, Leung TF, Thomas GN, Go MJ, Hara K, Sim X, Ho JS, Wang C, Li H, Lu L, Wang Y, Li JW, Wang Y, Lam VK, Wang J, Yu W, Kim YJ, Ng DP, Fujita H, Panoutsopoulou K, Day-Williams AG, Lee HM, Ng AC, Fang YJ, Kong AP, Jiang F, Ma X, Hou X, Tang S, Lu J, Yamauchi T, Tsui SK, Woo J, Leung PC, Zhang X, Tang NL, Sy HY, Liu J, Wong TY, Lee JY, Maeda S, Xu G, Cherny SS, Chan TF, Ng MC, Xiang K, Morris AP; DIAGRAM Consortium, Keildson S; MuTHER Consortium, Hu R, Ji L, Lin X, Cho YS, Kadowaki T, Tai ES, Zeggini E, McCarthy MI, Hon KL, Baum L, Tomlinson B, So WY, Bao Y, Chan JC, Jia W.

Diabetologia. 2013 Jun;56(6):1291-305. doi: 10.1007/s00125-013-2874-4. Epub 2013 Mar 27.

14.

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.

Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho WK, Rasheed A, Frossard P, Sim X, Hassanali N, Radha V, Chidambaram M, Liju S, Rees SD, Ng DP, Wong TY, Yamauchi T, Hara K, Tanaka Y, Hirose H, McCarthy MI, Morris AP; DIAGRAM; MuTHER; AGEN, Basit A, Barnett AH, Katulanda P, Matthews D, Mohan V, Wander GS, Singh JR, Mehra NK, Ralhan S, Kamboh MI, Mulvihill JJ, Maegawa H, Tobe K, Maeda S, Cho YS, Tai ES, Kelly MA, Chambers JC, Kooner JS, Kadowaki T, Deloukas P, Rader DJ, Danesh J, Sanghera DK.

Diabetes. 2013 May;62(5):1746-55. doi: 10.2337/db12-1077. Epub 2013 Jan 8.

15.

Is supervised exercise training safe in patients with anorexia nervosa? A meta-analysis.

Ng LW, Ng DP, Wong WP.

Physiotherapy. 2013 Mar;99(1):1-11. doi: 10.1016/j.physio.2012.05.006. Epub 2012 Aug 21.

PMID:
23219634
16.

Retrograde patient blood flow and rouleaux preventing red blood cell transfusion.

Dunbar NM, Marx-Wood CR, Maynard KJ, Ng DP, Szczepiorkowski ZM, Dumont LJ.

Transfusion. 2012 Nov;52(11):2284. doi: 10.1111/j.1537-2995.2012.03601.x. No abstract available.

PMID:
23140428
17.

Pentosidine levels in nonproteinuric diabetes associated with both low estimated glomerular filtration rate and cataract.

Lim XL, Teo BW, Tai BC, Wong TY, Ng DP.

Diabetes Metab Syndr Obes. 2012;5:155-64. doi: 10.2147/DMSO.S32283. Epub 2012 Jun 29.

18.

KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes.

Lim XL, Nurbaya S, Salim A, Tai ES, Maeda S, Nakamura Y, Ng DP.

Diabetologia. 2012 Sep;55(9):2402-6. doi: 10.1007/s00125-012-2602-5. Epub 2012 Jun 14.

PMID:
22696034
19.

Meta-analysis identifies common variants associated with body mass index in east Asians.

Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Le Marchand L, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C, Nakamura Y, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO.

Nat Genet. 2012 Feb 19;44(3):307-11. doi: 10.1038/ng.1087.

20.

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.

Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, Aung T, Cai Q, Chang LC, Chen YT, Gao Y, Hu FB, Kim HL, Kim S, Kim YJ, Lee JJ, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, Ng DP, Tay WT, Tsai FJ, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang TJ, Bao Y, Hedman ÅK, Morris AP, McCarthy MI; DIAGRAM Consortium; MuTHER Consortium, Takayanagi R, Park KS, Jia W, Chuang LM, Chan JC, Maeda S, Kadowaki T, Lee JY, Wu JY, Teo YY, Tai ES, Shu XO, Mohlke KL, Kato N, Han BG, Seielstad M.

Nat Genet. 2011 Dec 11;44(1):67-72. doi: 10.1038/ng.1019.

21.

A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations.

Wang X, Liu X, Sim X, Xu H, Khor CC, Ong RT, Tay WT, Suo C, Poh WT, Ng DP, Liu J, Aung T, Chia KS, Wong TY, Tai ES, Teo YY.

Eur J Hum Genet. 2012 Apr;20(4):469-75. doi: 10.1038/ejhg.2011.219. Epub 2011 Nov 30.

22.

A metabolomic study of low estimated GFR in non-proteinuric type 2 diabetes mellitus.

Ng DP, Salim A, Liu Y, Zou L, Xu FG, Huang S, Leong H, Ong CN.

Diabetologia. 2012 Feb;55(2):499-508. doi: 10.1007/s00125-011-2339-6. Epub 2011 Oct 25.

PMID:
22038517
23.

Membrane protein misassembly in disease.

Ng DP, Poulsen BE, Deber CM.

Biochim Biophys Acta. 2012 Apr;1818(4):1115-22. doi: 10.1016/j.bbamem.2011.07.046. Epub 2011 Aug 5. Review.

24.

Estimated glomerular filtration rate and its association with the retinol-binding protein 4 (RBP4) locus on human chromosome 10q23.

Ng DP, Salim A, Lim XL, Nurbaya S.

Nephrol Dial Transplant. 2012 Apr;27(4):1511-5. doi: 10.1093/ndt/gfr442. Epub 2011 Aug 5.

PMID:
21821833
25.

Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.

Dorajoo R, Blakemore AI, Sim X, Ong RT, Ng DP, Seielstad M, Wong TY, Saw SM, Froguel P, Liu J, Tai ES.

Int J Obes (Lond). 2012 Jan;36(1):159-63. doi: 10.1038/ijo.2011.86. Epub 2011 Apr 19.

PMID:
21544081
26.

Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

Sim X, Ong RT, Suo C, Tay WT, Liu J, Ng DP, Boehnke M, Chia KS, Wong TY, Seielstad M, Teo YY, Tai ES.

PLoS Genet. 2011 Apr;7(4):e1001363. doi: 10.1371/journal.pgen.1001363. Epub 2011 Apr 7.

27.

Nephrinuria associates with multiple renal traits in type 2 diabetes.

Ng DP, Tai BC, Tan E, Leong H, Nurbaya S, Lim XL, Chia KS, Wong CS, Lim WY, Holthöfer H.

Nephrol Dial Transplant. 2011 Aug;26(8):2508-14. doi: 10.1093/ndt/gfq738. Epub 2010 Dec 31.

PMID:
21196468
28.

Novel hydrophobic standards for membrane protein molecular weight determinations via sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

Rath A, Nadeau VG, Poulsen BE, Ng DP, Deber CM.

Biochemistry. 2010 Dec 21;49(50):10589-91. doi: 10.1021/bi101840j. Epub 2010 Nov 30.

PMID:
21105732
29.

Identification of new genetic risk variants for type 2 diabetes.

Shu XO, Long J, Cai Q, Qi L, Xiang YB, Cho YS, Tai ES, Li X, Lin X, Chow WH, Go MJ, Seielstad M, Bao W, Li H, Cornelis MC, Yu K, Wen W, Shi J, Han BG, Sim XL, Liu L, Qi Q, Kim HL, Ng DP, Lee JY, Kim YJ, Li C, Gao YT, Zheng W, Hu FB.

PLoS Genet. 2010 Sep 16;6(9):e1001127. doi: 10.1371/journal.pgen.1001127.

30.

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jørgensen T, Lauritzen T, Sandbæk A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T.

Nat Genet. 2010 Oct;42(10):864-8. doi: 10.1038/ng.660. Epub 2010 Sep 5.

PMID:
20818381
31.

Human genetics of diabetic retinopathy: current perspectives.

Ng DP.

J Ophthalmol. 2010;2010. pii: 172593. doi: 10.1155/2010/172593. Epub 2010 Jul 13.

32.

Modulation of the oligomerization of myelin proteolipid protein by transmembrane helix interaction motifs.

Ng DP, Deber CM.

Biochemistry. 2010 Aug 17;49(32):6896-902. doi: 10.1021/bi100739r.

PMID:
20695528
33.

Deletion of a terminal residue disrupts oligomerization of a transmembrane alpha-helix.

Ng DP, Deber CM.

Biochem Cell Biol. 2010 Apr;88(2):339-45. doi: 10.1139/o09-162.

PMID:
20453934
34.

Ethnicity, gender, genotype, and anger as related to nocturnal dipping.

Bishop GD, Ng DP, Ngau F, Nurbaya S.

Psychophysiology. 2010 Nov;47(6):1094-101. doi: 10.1111/j.1469-8986.2010.01011.x.

PMID:
20409018
35.

A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.

Maeda S, Kobayashi MA, Araki S, Babazono T, Freedman BI, Bostrom MA, Cooke JN, Toyoda M, Umezono T, Tarnow L, Hansen T, Gaede P, Jorsal A, Ng DP, Ikeda M, Yanagimoto T, Tsunoda T, Unoki H, Kawai K, Imanishi M, Suzuki D, Shin HD, Park KS, Kashiwagi A, Iwamoto Y, Kaku K, Kawamori R, Parving HH, Bowden DW, Pedersen O, Nakamura Y.

PLoS Genet. 2010 Feb 12;6(2):e1000842. doi: 10.1371/journal.pgen.1000842.

36.

International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants.

Truong T, Sauter W, McKay JD, Hosgood HD 3rd, Gallagher C, Amos CI, Spitz M, Muscat J, Lazarus P, Illig T, Wichmann HE, Bickeböller H, Risch A, Dienemann H, Zhang ZF, Naeim BP, Yang P, Zienolddiny S, Haugen A, Le Marchand L, Hong YC, Kim JH, Duell EJ, Andrew AS, Kiyohara C, Shen H, Matsuo K, Suzuki T, Seow A, Ng DP, Lan Q, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Constantinescu V, Bencko V, Foretova L, Janout V, Caporaso NE, Albanes D, Thun M, Landi MT, Trubicka J, Lener M, Lubinski J; EPIC-lung, Wang Y, Chabrier A, Boffetta P, Brennan P, Hung RJ.

Carcinogenesis. 2010 Apr;31(4):625-33. doi: 10.1093/carcin/bgq001. Epub 2010 Jan 27.

37.

Polymorphisms Identified through Genome-Wide Association Studies and Their Associations with Type 2 Diabetes in Chinese, Malays, and Asian-Indians in Singapore.

Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

Endocr Rev. 2009 Dec 1;30(7):926. doi: 10.1210/edrv.30.7.9999. No abstract available.

PMID:
28199501
38.

Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore.

Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

J Clin Endocrinol Metab. 2010 Jan;95(1):390-7. doi: 10.1210/jc.2009-0688. Epub 2009 Nov 5.

PMID:
19892838
39.

cMET and refractive error progression in children.

Khor CC, Grignani R, Ng DP, Toh KY, Chia KS, Tan D, Goh DL, Saw SM.

Ophthalmology. 2009 Aug;116(8):1469-74, 1474.e1. doi: 10.1016/j.ophtha.2009.02.026. Epub 2009 Jun 4.

PMID:
19500853
40.

Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.

Tan JT, Nurbaya S, Gardner D, Ye S, Tai ES, Ng DP.

Diabetes. 2009 Jun;58(6):1445-9. doi: 10.2337/db08-1138. Epub 2009 Feb 27.

41.

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB; DCCT/EDIC Research Group, Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Jun;58(6):1403-10. doi: 10.2337/db08-1514. Epub 2009 Feb 27.

42.

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.

Hung RJ, Christiani DC, Risch A, Popanda O, Haugen A, Zienolddiny S, Benhamou S, Bouchardy C, Lan Q, Spitz MR, Wichmann HE, LeMarchand L, Vineis P, Matullo G, Kiyohara C, Zhang ZF, Pezeshki B, Harris C, Mechanic L, Seow A, Ng DP, Szeszenia-Dabrowska N, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Mates D, Foretova L, Janout V, Bencko V, Caporaso N, Chen C, Duell EJ, Goodman G, Field JK, Houlston RS, Hong YC, Landi MT, Lazarus P, Muscat J, McLaughlin J, Schwartz AG, Shen H, Stucker I, Tajima K, Matsuo K, Thun M, Yang P, Wiencke J, Andrew AS, Monnier S, Boffetta P, Brennan P.

Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3081-9. doi: 10.1158/1055-9965.EPI-08-0411.

43.

Reduced GFR and albuminuria in Chinese type 2 diabetes mellitus patients are both independently associated with activation of the TNF-alpha system.

Ng DP, Fukushima M, Tai BC, Koh D, Leong H, Imura H, Lim XL.

Diabetologia. 2008 Dec;51(12):2318-24. doi: 10.1007/s00125-008-1162-1. Epub 2008 Oct 7.

PMID:
18839132
45.

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, Andersen G, Ng DP, Holmkvist J, Borch-Johnsen K, Jørgensen T, Sandbaek A, Lauritzen T, Hansen T, Nurbaya S, Tsunoda T, Kubo M, Babazono T, Hirose H, Hayashi M, Iwamoto Y, Kashiwagi A, Kaku K, Kawamori R, Tai ES, Pedersen O, Kamatani N, Kadowaki T, Kikkawa R, Nakamura Y, Maeda S.

Nat Genet. 2008 Sep;40(9):1098-102. doi: 10.1038/ng.208.

PMID:
18711366
47.

An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.

Ng DP, Nurbaya S, Ye SH, Krolewski AS.

Kidney Int. 2008 Aug;74(4):521-7. doi: 10.1038/ki.2008.202. Epub 2008 May 21.

48.

Genetic variation at the SLC12A3 locus is unlikely to explain risk for advanced diabetic nephropathy in Caucasians with type 2 diabetes.

Ng DP, Nurbaya S, Choo S, Koh D, Chia KS, Krolewski AS.

Nephrol Dial Transplant. 2008 Jul;23(7):2260-4. doi: 10.1093/ndt/gfm946. Epub 2008 Feb 10.

PMID:
18263927
49.

A randomised controlled trial of prophylactic levonorgestrel intrauterine system in tamoxifen-treated women.

Chan SS, Tam WH, Yeo W, Yu MM, Ng DP, Wong AW, Kwan WH, Yuen PM.

BJOG. 2007 Dec;114(12):1510-5.

50.

Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.

Kamiyama M, Kobayashi M, Araki S, Iida A, Tsunoda T, Kawai K, Imanishi M, Nomura M, Babazono T, Iwamoto Y, Kashiwagi A, Kaku K, Kawamori R, Ng DP, Hansen T, Gaede P, Pedersen O, Nakamura Y, Maeda S.

Hum Genet. 2007 Nov;122(3-4):397-407. Epub 2007 Aug 2.

PMID:
17671797

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