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The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development.

Shohayeb B, Ho U, Yeap YY, Parton RG, Millard SS, Xu Z, Piper M, Ng DCH.

Hum Mol Genet. 2019 Dec 9. pii: ddz281. doi: 10.1093/hmg/ddz281. [Epub ahead of print]


Catheter-Directed Computed Tomography Hepatic Angiography for Yttrium-90 Selective Internal Radiotherapy of Hepatocellular Carcinoma Reduces Prophylactic Embolization of Extrahepatic Vessels.

Goh WXT, Leong S, Too CW, Cheng LT, Saffari SE, Lee RZ, Ng STS, Lo RHG, Tay KH, Chan SXJM, Gogna A, Irani FG, Venkatanarasimha N, Loke KSH, Chow PKH, Ng DCE, Urlings TAJ, Patel A, Damodharan K, Toh LHW, Tan BS.

Cardiovasc Intervent Radiol. 2019 Nov 8. doi: 10.1007/s00270-019-02362-y. [Epub ahead of print]


Caring for the mother-child dyad as a family physician.

Tsang LPM, Ng DCC, Chan YH, Chen HY.

Singapore Med J. 2019 Oct;60(10):497-501. doi: 10.11622/smedj.2019128.


Current Status and Growth of Nuclear Theranostics in Singapore.

Huang HL, Tong AKT, Thang SP, Yan SX, Lam WWC, Loke KSH, Tang CYL, Cheng LTJ, Ooi GSK, Low HC, Magsombol BM, Tham WY, Goh CXY, Tan CJ, Khor YM, Zaheer S, Bharadwaj P, Xie W, Ng DCE.

Nucl Med Mol Imaging. 2019 Apr;53(2):96-101. doi: 10.1007/s13139-019-00580-3. Epub 2019 Jan 25.


Invasive Salmonella infections among children in Bintulu, Sarawak, Malaysian Borneo: a 6-year retrospective review.

Mohan A, Munusamy C, Tan YC, Muthuvelu S, Hashim R, Chien SL, Wong MK, Khairuddin NA, Podin Y, Lau PS, Ng DC, Ooi MH.

BMC Infect Dis. 2019 Apr 18;19(1):330. doi: 10.1186/s12879-019-3963-x.


Pathogenic E2K mutation of doublecortin X (DCX) alters microtubule stabilisation and actin filament association.

Moslehi M, Ng DCH, Bogoyevitch MA.

Biochem Biophys Res Commun. 2019 Jun 4;513(3):540-545. doi: 10.1016/j.bbrc.2019.04.005. Epub 2019 Apr 9.


Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death.

Hoque A, Williamson NA, Ameen SS, Ciccotosto GD, Hossain MI, Oakhill JS, Ng DCH, Ang CS, Cheng HC.

Cell Death Dis. 2019 Mar 1;10(3):213. doi: 10.1038/s41419-019-1445-0.


Doublecortin X (DCX) serine 28 phosphorylation is a regulatory switch, modulating association of DCX with microtubules and actin filaments.

Moslehi M, Ng DCH, Bogoyevitch MA.

Biochim Biophys Acta Mol Cell Res. 2019 Apr;1866(4):638-649. doi: 10.1016/j.bbamcr.2019.01.003. Epub 2019 Jan 6.


MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis.

Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, Feng Y, Ma T, Wang Y, Ng DCH, Niu X, Su B, Behrens A, Xu Z.

PLoS Biol. 2018 Dec 19;16(12):e2006613. doi: 10.1371/journal.pbio.2006613. eCollection 2018 Dec.


Unilateral periorbital swelling with vesicular golden crust forehead rash.

Khoo EJ, Vijayakulasingam T, Ng DC.

J Paediatr Child Health. 2018 Dec;54(12):1397. doi: 10.1111/jpc.2_14277. No abstract available.


Unilateral periorbital swelling with vesicular golden crust forehead rash.

Khoo EJ, Vijayakulasingam T, Ng DC.

J Paediatr Child Health. 2018 Dec;54(12):1394. doi: 10.1111/jpc.1_14277. No abstract available.


Clinicopathologic Characteristics and Survival of Patients with Gastroenteropancreatic Neuroendocrine Neoplasm in a Multi-Ethnic Asian Institution.

Tai WM, Tan SH, Tan DMY, Loke KSH, Ng DCE, Yan SX, Hwang JSG, Lim KH, Loh LM, Kek PC, Goh BKP, Lee SY, Chung AYF, Ong SYK.

Neuroendocrinology. 2019;108(4):265-277. doi: 10.1159/000495140. Epub 2018 Nov 6.


Integrated Dissection of Cysteine Oxidative Post-translational Modification Proteome During Cardiac Hypertrophy.

Wang J, Choi H, Chung NC, Cao Q, Ng DCM, Mirza B, Scruggs SB, Wang D, Garlid AO, Ping P.

J Proteome Res. 2018 Dec 7;17(12):4243-4257. doi: 10.1021/acs.jproteome.8b00372. Epub 2018 Aug 31.


Heart healthy integrative nutritional counseling (H2INC): Creating a Chinese medicine + western medicine patient education curriculum for Chinese Americans.

Ho EY, Acquah J, Chao C, Leung G, Ng DC, Chao MT, Wang A, Ku S, Chen W, Yu CK, Xu S, Chen M, Jih J.

Patient Educ Couns. 2018 Dec;101(12):2202-2208. doi: 10.1016/j.pec.2018.08.011. Epub 2018 Aug 9.


Effectiveness of proximal interphalangeal joint-blocking orthosis vs metacarpophalangeal joint-blocking orthosis in trigger digit management: A randomized clinical trial.

Teo SH, Ng DCL, Wong YKY.

J Hand Ther. 2019 Oct - Dec;32(4):444-451. doi: 10.1016/j.jht.2018.02.007. Epub 2018 Jul 18.


18F-FDG PET-MRI with T1 MOLLI mapping to detect systemic sclerosis bowel inflammation and fibrosis.

Marchesseau S, Ng SA, Wang YT, Xie W, Ng DC, Totman JJ, Low AHL.

Eur J Radiol. 2018 Aug;105:289-295. doi: 10.1016/j.ejrad.2018.06.022. Epub 2018 Jun 26.


Quantitative temporal analysis of protein dynamics in cardiac remodeling.

McClatchy DB, Ma Y, Liem DA, Ng DCM, Ping P, Yates JR 3rd.

J Mol Cell Cardiol. 2018 Aug;121:163-172. doi: 10.1016/j.yjmcc.2018.07.126. Epub 2018 Jul 19.


Complications of 90Y Transarterial Radioembolization of Hepatic Tumors: Primer for Interventional Radiology Residents and Fellows RadioGraphics Fundamentals | Online Presentation.

Venkatanarasimha N, Gogna A, Muli Jogi R, Damodharan K, Chan SX, Ng DCE, Loke KSH, Irani FG, Lo RHG, Chandramohan S.

Radiographics. 2018 Jul-Aug;38(4):1282-1283. doi: 10.1148/rg.2018180062. Review. No abstract available.


Flavonols and Flavones - Protecting Against Myocardial Ischemia/Reperfusion Injury by Targeting Protein Kinases.

Woodman OL, Chin KY, Thomas CJ, Ng DCH, May CN.

Curr Med Chem. 2018;25(34):4402-4415. doi: 10.2174/0929867325666180326161730. Review.


SIRveNIB: Selective Internal Radiation Therapy Versus Sorafenib in Asia-Pacific Patients With Hepatocellular Carcinoma.

Chow PKH, Gandhi M, Tan SB, Khin MW, Khasbazar A, Ong J, Choo SP, Cheow PC, Chotipanich C, Lim K, Lesmana LA, Manuaba TW, Yoong BK, Raj A, Law CS, Cua IHY, Lobo RR, Teh CSC, Kim YH, Jong YW, Han HS, Bae SH, Yoon HK, Lee RC, Hung CF, Peng CY, Liang PC, Bartlett A, Kok KYY, Thng CH, Low AS, Goh ASW, Tay KH, Lo RHG, Goh BKP, Ng DCE, Lekurwale G, Liew WM, Gebski V, Mak KSW, Soo KC; Asia-Pacific Hepatocellular Carcinoma Trials Group.

J Clin Oncol. 2018 Jul 1;36(19):1913-1921. doi: 10.1200/JCO.2017.76.0892. Epub 2018 Mar 2.


Factors that influence adult neurogenesis as potential therapy.

Shohayeb B, Diab M, Ahmed M, Ng DCH.

Transl Neurodegener. 2018 Feb 21;7:4. doi: 10.1186/s40035-018-0109-9. eCollection 2018. Review.


Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2.

Chin KY, Silva LS, Darby IA, Ng DCH, Woodman OL.

Int J Cardiol. 2018 Mar 1;254:265-271. doi: 10.1016/j.ijcard.2017.11.101. Epub 2018 Jan 28.


Integrated omics dissection of proteome dynamics during cardiac remodeling.

Lau E, Cao Q, Lam MPY, Wang J, Ng DCM, Bleakley BJ, Lee JM, Liem DA, Wang D, Hermjakob H, Ping P.

Nat Commun. 2018 Jan 9;9(1):120. doi: 10.1038/s41467-017-02467-3.


Prospective study to determine early hypertrophy of the contra-lateral liver lobe after unilobar, Yttrium-90, selective internal radiation therapy in patients with hepatocellular carcinoma.

Teo JY, Allen JC, Ng DCE, Abdul Latiff JB, Choo SP, Tai DW, Low ASC, Cheah FK, Chang JPE, Kam JH, Lee VTW, Chung AYF, Chan CY, Chow PKH, Goh BKP.

Surgery. 2018 May;163(5):1008-1013. doi: 10.1016/j.surg.2017.10.014. Epub 2018 Jan 3.


Validating a Culturally-sensitive Social Competence Training Programme for Adolescents with ASD in a Chinese Context: An Initial Investigation.

Chan RWS, Leung CNW, Ng DCY, Yau SSW.

J Autism Dev Disord. 2018 Feb;48(2):450-460. doi: 10.1007/s10803-017-3335-6.


Unequal pupils in an asthmatic child.

Ng DC, Shangkeree RP, Khoo EJ.

J Paediatr Child Health. 2017 Oct;53(10):1024-1025. doi: 10.1111/jpc.1_13531. No abstract available.


The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development.

Shohayeb B, Lim NR, Ho U, Xu Z, Dottori M, Quinn L, Ng DCH.

Mol Neurobiol. 2018 Jul;55(7):5409-5424. doi: 10.1007/s12035-017-0778-x. Epub 2017 Sep 22. Review.


Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus.

Moslehi M, Ng DCH, Bogoyevitch MA.

Sci Rep. 2017 Jul 12;7(1):5245. doi: 10.1038/s41598-017-05340-x.


WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells.

Alshawaf AJ, Antonic A, Skafidas E, Ng DC, Dottori M.

Stem Cells Int. 2017;2017:7848932. doi: 10.1155/2017/7848932. Epub 2017 Jun 13.


Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth.

Lim NR, Shohayeb B, Zaytseva O, Mitchell N, Millard SS, Ng DCH, Quinn LM.

Stem Cell Reports. 2017 Jul 11;9(1):32-41. doi: 10.1016/j.stemcr.2017.05.015. Epub 2017 Jun 15.


Intravenous lignocaine infusion facilitates acute rehabilitation after laparoscopic colectomy in the Chinese patients.

Lee MW, Or DY, Tsang AC, Ng DC, Chen PP, Cheung MH, Li RS, Leong HT.

Hong Kong Med J. 2017 Oct;23(5):441-5. doi: 10.12809/hkmj164984. Epub 2017 Jan 27.


Cardiovascular proteomics in the era of big data: experimental and computational advances.

Lam MP, Lau E, Ng DC, Wang D, Ping P.

Clin Proteomics. 2016 Dec 5;13:23. eCollection 2016. Review.


Single administration of Selective Internal Radiation Therapy versus continuous treatment with sorafeNIB in locally advanced hepatocellular carcinoma (SIRveNIB): study protocol for a phase iii randomized controlled trial.

Gandhi M, Choo SP, Thng CH, Tan SB, Low AS, Cheow PC, Goh AS, Tay KH, Lo RH, Goh BK, Wong JS, Ng DC, Soo KC, Liew WM, Chow PK; Asia-Pacific Hepatocellular Carcinoma Trials Group.

BMC Cancer. 2016 Nov 7;16(1):856.


Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems.

Lam MP, Venkatraman V, Xing Y, Lau E, Cao Q, Ng DC, Su AI, Ge J, Van Eyk JE, Ping P.

J Proteome Res. 2016 Nov 4;15(11):4126-4134. Epub 2016 Jul 19.


National Cancer Centre Singapore Consensus Guidelines for Hepatocellular Carcinoma.

Chow PK, Choo SP, Ng DC, Lo RH, Wang ML, Toh HC, Tai DW, Goh BK, Wong JS, Tay KH, Goh AS, Yan SX, Loke KS, Thang SP, Gogna A, Too CW, Irani FG, Leong S, Lim KH, Thng CH.

Liver Cancer. 2016 Apr;5(2):97-106. doi: 10.1159/000367759. Epub 2016 Mar 17.


Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration.

Fife CM, Sagnella SM, Teo WS, Po'uha ST, Byrne FL, Yeap YY, Ng DC, Davis TP, McCarroll JA, Kavallaris M.

Oncogene. 2017 Jan 26;36(4):501-511. doi: 10.1038/onc.2016.220. Epub 2016 Jun 20.


Early clearance of Chikungunya virus in children is associated with a strong innate immune response.

Simarmata D, Ng DC, Kam YW, Lee B, Sum MS, Her Z, Chow A, Leo YS, Cardosa J, Perera D, Ooi MH, Ng LF.

Sci Rep. 2016 May 16;6:26097. doi: 10.1038/srep26097.


Current role of selective internal radiation with yttrium-90 in liver tumors.

Lau WY, Teoh YL, Win KM, Lee RC, de Villa VH, Kim YH, Liang PC, Santos-Ocampo RS, Lo RH, Lim KB, Tai DW, Ng DC, Irani FG, Gogna A, Chow PK.

Future Oncol. 2016 May;12(9):1193-204. doi: 10.2217/fon-2016-0035. Epub 2016 Mar 23. Review. Erratum in: Future Oncol. 2016 Sep;12 (18):2174.


A large dataset of protein dynamics in the mammalian heart proteome.

Lau E, Cao Q, Ng DC, Bleakley BJ, Dincer TU, Bot BM, Wang D, Liem DA, Lam MP, Ge J, Ping P.

Sci Data. 2016 Mar 15;3:160015. doi: 10.1038/sdata.2016.15.


Yttrium-90 hepatic radioembolization: clinical review and current techniques in interventional radiology and personalized dosimetry.

Tong AK, Kao YH, Too CW, Chin KF, Ng DC, Chow PK.

Br J Radiol. 2016 Jun;89(1062):20150943. doi: 10.1259/bjr.20150943. Epub 2016 Mar 24. Review.


A beacon of hope in stroke therapy-Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies.

Hoque A, Hossain MI, Ameen SS, Ang CS, Williamson N, Ng DC, Chueh AC, Roulston C, Cheng HC.

Pharmacol Ther. 2016 Apr;160:159-79. doi: 10.1016/j.pharmthera.2016.02.009. Epub 2016 Feb 17. Review.


A systematic review of contralateral liver lobe hypertrophy after unilobar selective internal radiation therapy with Y90.

Teo JY, Allen JC Jr, Ng DC, Choo SP, Tai DW, Chang JP, Cheah FK, Chow PK, Goh BK.

HPB (Oxford). 2016 Jan;18(1):7-12. doi: 10.1016/j.hpb.2015.07.002. Epub 2015 Dec 11. Review.


Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.

Lim NR, Yeap YY, Ang CS, Williamson NA, Bogoyevitch MA, Quinn LM, Ng DC.

Cell Cycle. 2016;15(3):413-24. doi: 10.1080/15384101.2015.1127472.


Gender, Race, and Age at Diagnosis as Risk Factors for Metastasis or Recurrence among 1,657 Thyroid Cancer Patients Treated with Radioiodine across 40 Years in Singapore.

Kao YH, Gan HK, Zaheer S, Lam WW, Loke KS, Wong WY, Ng DC, Goh AS.

Oncol Res Treat. 2015;38(12):679-82. doi: 10.1159/000442114. Epub 2015 Nov 18.


A systematic review of contralateral liver lobe hypertrophy after unilobar selective internal radiation therapy with Y90.

Teo JY, Allen JC Jr, Ng DC, Choo SP, Tai DW, Chang JP, Cheah FK, Chow PK, Goh BK.

HPB (Oxford). 2015 Oct 16. doi: 10.1111/hpb.12490. [Epub ahead of print] Review.


The incidence and sites of Nasopharyngeal carcinoma (NPC) metastases on FDG PET/CT scans.

Al Tamimi AS, Zaheer S, Ng DC, Osmany S.

Oral Oncol. 2015 Nov;51(11):1047-1050. doi: 10.1016/j.oraloncology.2015.08.001. Epub 2015 Aug 24.


Phosphaturic mesenchymal tumour mixed connective tissue variant: report of three cases with unusual histological findings.

Shustik DA, Ng DC, Sittampalam K.

Int J Clin Exp Pathol. 2015 Jun 1;8(6):7506-17. eCollection 2015.

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