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Superhydrophobic Polydimethylsiloxane via Nanocontact Molding of Solvent Crystallized Polycarbonate: Optimized Fabrication, Mechanistic Investigation, and Application Potential.

Schultz CW, Ng CLW, Yu HZ.

ACS Appl Mater Interfaces. 2020 Jan 15;12(2):3161-3170. doi: 10.1021/acsami.9b18041. Epub 2020 Jan 3.


Anterior Nasal Spine Relocation for Caudal Septal Deviation: A Case Series and Discussion of Common Scenarios.

Ng CL, Rival R, Solomon P.

Aesthetic Plast Surg. 2019 Dec 9. doi: 10.1007/s00266-019-01568-2. [Epub ahead of print]


Time to computed tomography: does this affect trauma patient outcomes? A retrospective analysis at an Australian major trauma centre.

Ng CLH, Kim J, Dobson B, Campbell D, Wullschleger M.

ANZ J Surg. 2019 Nov;89(11):1475-1479. doi: 10.1111/ans.15470. Epub 2019 Nov 5.


Traumatic Vidian Nerve Injury: An Underrecognized Complication in Basisphenoid Fractures.

Chee J, Ng CL.

JAMA Otolaryngol Head Neck Surg. 2019 Sep 26. doi: 10.1001/jamaoto.2019.2796. [Epub ahead of print] No abstract available.


Notch and Delta are required for survival of the germline stem cell lineage in testes of Drosophila melanogaster.

Ng CL, Qian Y, Schulz C.

PLoS One. 2019 Sep 12;14(9):e0222471. doi: 10.1371/journal.pone.0222471. eCollection 2019.


Plasmodium falciparum In Vitro Drug Resistance Selections and Gene Editing.

Ng CL, Fidock DA.

Methods Mol Biol. 2019;2013:123-140. doi: 10.1007/978-1-4939-9550-9_9.


Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents.

Stokes BH, Yoo E, Murithi JM, Luth MR, Afanasyev P, da Fonseca PCA, Winzeler EA, Ng CL, Bogyo M, Fidock DA.

PLoS Pathog. 2019 Jun 6;15(6):e1007722. doi: 10.1371/journal.ppat.1007722. eCollection 2019 Jun.


Crystal structure and epitope analysis of house dust mite allergen Der f 21.

Pang SL, Ho KL, Waterman J, Rambo RP, Teh AH, Mathavan I, Harris G, Beis K, Say YH, Anusha MS, Sio YY, Chew FT, Ng CL.

Sci Rep. 2019 Mar 20;9(1):4933. doi: 10.1038/s41598-019-40879-x.


A Theory-based Educational Pamphlet With Low-residue Diet Improves Colonoscopy Attendance and Bowel Preparation Quality.

Gausman V, Quarta G, Lee MH, Chtourmine N, Ganotisi C, Nanton-Gonzalez F, Ng CL, Jun J, Perez L, Dominitz JA, Sherman SE, Poles MA, Liang PS.

J Clin Gastroenterol. 2020 Feb;54(2):164-169. doi: 10.1097/MCG.0000000000001151.


Functional Genomics.

Goh HH, Ng CL, Loke KK.

Adv Exp Med Biol. 2018;1102:11-30. doi: 10.1007/978-3-319-98758-3_2. Review.


Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.

White J, Dhingra SK, Deng X, El Mazouni F, Lee MCS, Afanador GA, Lawong A, Tomchick DR, Ng CL, Bath J, Rathod PK, Fidock DA, Phillips MA.

ACS Infect Dis. 2019 Jan 11;5(1):90-101. doi: 10.1021/acsinfecdis.8b00211. Epub 2018 Nov 13.


Crystal structure and functional analysis of human C1ORF123.

A Rahaman SN, Mat Yusop J, Mohamed-Hussein ZA, Aizat WM, Ho KL, Teh AH, Waterman J, Tan BK, Tan HL, Li AY, Chen ES, Ng CL.

PeerJ. 2018 Sep 28;6:e5377. doi: 10.7717/peerj.5377. eCollection 2018.


Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors.

Yoo E, Stokes BH, de Jong H, Vanaerschot M, Kumar T, Lawrence N, Njoroge M, Garcia A, Van der Westhuyzen R, Momper JD, Ng CL, Fidock DA, Bogyo M.

J Am Chem Soc. 2018 Sep 12;140(36):11424-11437. doi: 10.1021/jacs.8b06656. Epub 2018 Aug 29.


Effects of meaningful weight loss beyond symptomatic relief in adults with knee osteoarthritis and obesity: a systematic review and meta-analysis.

Chu IJH, Lim AYT, Ng CLW.

Obes Rev. 2018 Nov;19(11):1597-1607. doi: 10.1111/obr.12726. Epub 2018 Jul 27.


Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study.

Llanos-Cuentas A, Casapia M, Chuquiyauri R, Hinojosa JC, Kerr N, Rosario M, Toovey S, Arch RH, Phillips MA, Rozenberg FD, Bath J, Ng CL, Cowell AN, Winzeler EA, Fidock DA, Baker M, Möhrle JJ, Hooft van Huijsduijnen R, Gobeau N, Araeipour N, Andenmatten N, Rückle T, Duparc S.

Lancet Infect Dis. 2018 Aug;18(8):874-883. doi: 10.1016/S1473-3099(18)30309-8. Epub 2018 Jun 13. Erratum in: Lancet Infect Dis. 2018 Aug;18(8):829.


Metabolomics data of Mitragyna speciosa leaf using LC-ESI-TOF-MS.

Veeramohan R, Azizan KA, Aizat WM, Goh HH, Mansor SM, Yusof NSM, Baharum SN, Ng CL.

Data Brief. 2018 Apr 4;18:1212-1216. doi: 10.1016/j.dib.2018.04.001. eCollection 2018 Jun.


Impact of financial background and student debt on postgraduate residency choices of medical students in Singapore.

Fong JMN, Tan YTW, Sayampanathan AA, Mohan N, Koh YQ, Jang JHJ, Low JRI, Vasudevan A, Ng CL, Tambyah PA.

Singapore Med J. 2018 Dec;59(12):647-651. doi: 10.11622/smedj.2018068. Epub 2018 Jun 7.


The clinical characteristics and histopathological features of chronic rhinosinusitis with unilateral nasal polyps in 136 patients in Southern China.

Chen Z, Peng Y, Ng CL, Jin P, Liu J, Li YY, Yan Y, Liu YH, Luo XL, Qiu QH, Wang DY.

Clin Otolaryngol. 2018 Oct;43(5):1345-1349. doi: 10.1111/coa.13147. Epub 2018 Jun 13. No abstract available.


The efficacy of sublingual immunotherapy for allergic diseases in Asia.

Liu X, Ng CL, Wang Y.

Allergol Int. 2018 Jul;67(3):309-319. doi: 10.1016/j.alit.2018.02.007. Epub 2018 Mar 16. Review.


Factors affecting choice of sponsoring institution for residency among medical students in Singapore.

Ng CL, Liu XD, Murali Govind R, Tan JWJ, Ooi SBS, Archuleta S.

Singapore Med J. 2018 Dec;59(12):642-646. doi: 10.11622/smedj.2018024. Epub 2018 Mar 16.


Pulmonary melioidosis with laryngeal involvement: an unusual site of infection.

Ng CL, Liu X, Tan NJH, Prasad VMN, Lee P.

Thorax. 2018 Jan 26. pii: thoraxjnl-2017-211046. doi: 10.1136/thoraxjnl-2017-211046. [Epub ahead of print] No abstract available.


Clinical Characteristics and Allergen Sensitization Patterns of Patients with Local Allergic Rhinitis in Southern China.

Tao XY, Ng CL, Chen D, Lin ZB, Wu SL, Liang MJ, Li CW, Xu R.

Int Arch Allergy Immunol. 2018;175(1-2):107-113. doi: 10.1159/000485896. Epub 2018 Jan 20.


A Prototype Sensor for In Situ Sensing of Fine Particulate Matter and Volatile Organic Compounds.

Ng CL, Kai FM, Tee MH, Tan N, Hemond HF.

Sensors (Basel). 2018 Jan 18;18(1). pii: E265. doi: 10.3390/s18010265.


Structural and kinetic studies of a novel nerol dehydrogenase from Persicaria minor, a nerol-specific enzyme for citral biosynthesis.

Tan CS, Hassan M, Mohamed Hussein ZA, Ismail I, Ho KL, Ng CL, Zainal Z.

Plant Physiol Biochem. 2018 Feb;123:359-368. doi: 10.1016/j.plaphy.2017.12.033. Epub 2017 Dec 26.


Genomic characterization of a new endophytic Streptomyces kebangsaanensis identifies biosynthetic pathway gene clusters for novel phenazine antibiotic production.

Remali J, Sarmin N'M, Ng CL, Tiong JJL, Aizat WM, Keong LK, Zin NM.

PeerJ. 2017 Nov 29;5:e3738. doi: 10.7717/peerj.3738. eCollection 2017.


Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity.

Vanaerschot M, Lucantoni L, Li T, Combrinck JM, Ruecker A, Kumar TRS, Rubiano K, Ferreira PE, Siciliano G, Gulati S, Henrich PP, Ng CL, Murithi JM, Corey VC, Duffy S, Lieberman OJ, Veiga MI, Sinden RE, Alano P, Delves MJ, Lee Sim K, Winzeler EA, Egan TJ, Hoffman SL, Avery VM, Fidock DA.

Nat Microbiol. 2017 Oct;2(10):1403-1414. doi: 10.1038/s41564-017-0007-4. Epub 2017 Aug 14.


Effect on health-related quality of life of ongoing feedback during a 12-month maintenance walking programme in patients with COPD: a randomized controlled trial.

Wootton SL, McKeough Z, Ng CLW, Jenkins S, Hill K, Eastwood PR, Hillman D, Jenkins C, Cecins N, Spencer L, Alison J.

Respirology. 2018 Jan;23(1):60-67. doi: 10.1111/resp.13128. Epub 2017 Jul 30.


Primary nasopharyngeal polyps: a case series on a rare clinical entity.

Chen H, Mo MQ, Ng CL, Lin ZB, Li TY, Wen WP, Li CW.

Eur Arch Otorhinolaryngol. 2017 Oct;274(10):3659-3665. doi: 10.1007/s00405-017-4682-9. Epub 2017 Jul 26.


Protein Degradation Systems as Antimalarial Therapeutic Targets.

Ng CL, Fidock DA, Bogyo M.

Trends Parasitol. 2017 Sep;33(9):731-743. doi: 10.1016/ Epub 2017 Jul 5. Review.


Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element.

Leung W, Shaffer CD, Chen EJ, Quisenberry TJ, Ko K, Braverman JM, Giarla TC, Mortimer NT, Reed LK, Smith ST, Robic S, McCartha SR, Perry DR, Prescod LM, Sheppard ZA, Saville KJ, McClish A, Morlock EA, Sochor VR, Stanton B, Veysey-White IC, Revie D, Jimenez LA, Palomino JJ, Patao MD, Patao SM, Himelblau ET, Campbell JD, Hertz AL, McEvilly MF, Wagner AR, Youngblom J, Bedi B, Bettincourt J, Duso E, Her M, Hilton W, House S, Karimi M, Kumimoto K, Lee R, Lopez D, Odisho G, Prasad R, Robbins HL, Sandhu T, Selfridge T, Tsukashima K, Yosif H, Kokan NP, Britt L, Zoellner A, Spana EP, Chlebina BT, Chong I, Friedman H, Mammo DA, Ng CL, Nikam VS, Schwartz NU, Xu TQ, Burg MG, Batten SM, Corbeill LM, Enoch E, Ensign JJ, Franks ME, Haiker B, Ingles JA, Kirkland LD, Lorenz-Guertin JM, Matthews J, Mittig CM, Monsma N, Olson KJ, Perez-Aragon G, Ramic A, Ramirez JR, Scheiber C, Schneider PA, Schultz DE, Simon M, Spencer E, Wernette AC, Wykle ME, Zavala-Arellano E, McDonald MJ, Ostby K, Wendland P, DiAngelo JR, Ceasrine AM, Cox AH, Docherty JEB, Gingras RM, Grieb SM, Pavia MJ, Personius CL, Polak GL, Beach DL, Cerritos HL, Horansky EA, Sharif KA, Moran R, Parrish S, Bickford K, Bland J, Broussard J, Campbell K, Deibel KE, Forka R, Lemke MC, Nelson MB, O'Keeffe C, Ramey SM, Schmidt L, Villegas P, Jones CJ, Christ SL, Mamari S, Rinaldi AS, Stity G, Hark AT, Scheuerman M, Silver Key SC, McRae BD, Haberman AS, Asinof S, Carrington H, Drumm K, Embry T, McGuire R, Miller-Foreman D, Rosen S, Safa N, Schultz D, Segal M, Shevin Y, Svoronos P, Vuong T, Skuse G, Paetkau DW, Bridgman RK, Brown CM, Carroll AR, Gifford FM, Gillespie JB, Herman SE, Holtcamp KL, Host MA, Hussey G, Kramer DM, Lawrence JQ, Martin MM, Niemiec EN, O'Reilly AP, Pahl OA, Quintana G, Rettie EAS, Richardson TL, Rodriguez AE, Rodriguez MO, Schiraldi L, Smith JJ, Sugrue KF, Suriano LJ, Takach KE, Vasquez AM, Velez X, Villafuerte EJ, Vives LT, Zellmer VR, Hauke J, Hauser CR, Barker K, Cannon L, Parsamian P, Parsons S, Wichman Z, Bazinet CW, Johnson DE, Bangura A, Black JA, Chevee V, Einsteen SA, Hilton SK, Kollmer M, Nadendla R, Stamm J, Fafara-Thompson AE, Gygi AM, Ogawa EE, Van Camp M, Kocsisova Z, Leatherman JL, Modahl CM, Rubin MR, Apiz-Saab SS, Arias-Mejias SM, Carrion-Ortiz CF, Claudio-Vazquez PN, Espada-Green DM, Feliciano-Camacho M, Gonzalez-Bonilla KM, Taboas-Arroyo M, Vargas-Franco D, Montañez-Gonzalez R, Perez-Otero J, Rivera-Burgos M, Rivera-Rosario FJ, Eisler HL, Alexander J, Begley SK, Gabbard D, Allen RJ, Aung WY, Barshop WD, Boozalis A, Chu VP, Davis JS, Duggal RN, Franklin R, Gavinski K, Gebreyesus H, Gong HZ, Greenstein RA, Guo AD, Hanson C, Homa KE, Hsu SC, Huang Y, Huo L, Jacobs S, Jia S, Jung KL, Wai-Chee Kong S, Kroll MR, Lee BM, Lee PF, Levine KM, Li AS, Liu C, Liu MM, Lousararian AP, Lowery PB, Mallya AP, Marcus JE, Ng PC, Nguyen HP, Patel R, Precht H, Rastogi S, Sarezky JM, Schefkind A, Schultz MB, Shen D, Skorupa T, Spies NC, Stancu G, Vivian Tsang HM, Turski AL, Venkat R, Waldman LE, Wang K, Wang T, Wei JW, Wu DY, Xiong DD, Yu J, Zhou K, McNeil GP, Fernandez RW, Menzies PG, Gu T, Buhler J, Mardis ER, Elgin SCR.

G3 (Bethesda). 2017 Aug 7;7(8):2439-2460. doi: 10.1534/g3.117.040907.


Whole-genome shotgun sequence of phenazine-producing endophytic Streptomyces kebangsaanensis SUK12.

Remali J, Loke KK, Ng CL, Aizat WM, Tiong J, Zin NM.

Genom Data. 2017 May 24;13:7-10. doi: 10.1016/j.gdata.2017.05.015. eCollection 2017 Sep.


Following Instructions in Patients With Schizophrenia: The Benefits of Actions at Encoding and Recall.

Lui SSY, Yang TX, Ng CLY, Wong PTY, Wong JOY, Ettinger U, Cheung EFC, Chan RCK.

Schizophr Bull. 2018 Jan 13;44(1):137-146. doi: 10.1093/schbul/sbx026.


A Multi-Platform Optical Sensor for In Vivo and In Vitro Algae Classification.

Ng CL, Chen QQ, Chua JJ, Hemond HF.

Sensors (Basel). 2017 Apr 20;17(4). pii: E912. doi: 10.3390/s17040912.


Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study.

McCarthy JS, Lotharius J, Rückle T, Chalon S, Phillips MA, Elliott S, Sekuloski S, Griffin P, Ng CL, Fidock DA, Marquart L, Williams NS, Gobeau N, Bebrevska L, Rosario M, Marsh K, Möhrle JJ.

Lancet Infect Dis. 2017 Jun;17(6):626-635. doi: 10.1016/S1473-3099(17)30171-8. Epub 2017 Mar 28.


Characterization of Textile-Insulated Capacitive Biosensors.

Ng CL, Reaz MB.

Sensors (Basel). 2017 Mar 12;17(3). pii: E574. doi: 10.3390/s17030574.


Purification and biochemical characterization of recombinant Persicaria minor β-sesquiphellandrene synthase.

Ker DS, Pang SL, Othman NF, Kumaran S, Tan EF, Krishnan T, Chan KG, Othman R, Hassan M, Ng CL.

PeerJ. 2017 Feb 28;5:e2961. doi: 10.7717/peerj.2961. eCollection 2017.


A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue.

Sonoiki E, Ng CL, Lee MC, Guo D, Zhang YK, Zhou Y, Alley MR, Ahyong V, Sanz LM, Lafuente-Monasterio MJ, Dong C, Schupp PG, Gut J, Legac J, Cooper RA, Gamo FJ, DeRisi J, Freund YR, Fidock DA, Rosenthal PJ.

Nat Commun. 2017 Mar 6;8:14574. doi: 10.1038/ncomms14574.


Crystallization and X-ray crystallographic analysis of recombinant TylP, a putative γ-butyrolactone receptor protein from Streptomyces fradiae.

Mohd-Sharif N, Shaibullah S, Givajothi V, Tan CS, Ho KL, Teh AH, Baharum SN, Waterman J, Ng CL.

Acta Crystallogr F Struct Biol Commun. 2017 Feb 1;73(Pt 2):109-115. doi: 10.1107/S2053230X17001212. Epub 2017 Jan 31.


Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

Le Bihan A, de Kanter R, Angulo-Barturen I, Binkert C, Boss C, Brun R, Brunner R, Buchmann S, Burrows J, Dechering KJ, Delves M, Ewerling S, Ferrer S, Fischli C, Gamo-Benito FJ, Gnädig NF, Heidmann B, Jiménez-Díaz MB, Leroy D, Martínez MS, Meyer S, Moehrle JJ, Ng CL, Noviyanti R, Ruecker A, Sanz LM, Sauerwein RW, Scheurer C, Schleiferboeck S, Sinden R, Snyder C, Straimer J, Wirjanata G, Marfurt J, Price RN, Weller T, Fischli W, Fidock DA, Clozel M, Wittlin S.

PLoS Med. 2016 Oct 4;13(10):e1002138. doi: 10.1371/journal.pmed.1002138. eCollection 2016 Oct.


Solubilization and formulation of chrysosplenol C in solid dispersion with hydrophilic carriers.

Ng CL, Lee SE, Lee JK, Kim TH, Jang WS, Choi JS, Kim YH, Kim JK, Park JS.

Int J Pharm. 2016 Oct 15;512(1):314-321. doi: 10.1016/j.ijpharm.2016.08.062. Epub 2016 Sep 1.


Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic Pathway in Plant.

Seman-Kamarulzaman AF, Mohamed-Hussein ZA, Ng CL, Hassan M.

PLoS One. 2016 Aug 25;11(8):e0161707. doi: 10.1371/journal.pone.0161707. eCollection 2016.


An update on finances and financial support for medical students in Yong Loo Lin School of Medicine.

Sayampanathan AA, Tan YT, Fong JM, Koh YQ, Ng CL, Mohan N, Jang JH, Tambyah PA.

Singapore Med J. 2017 Apr;58(4):206-211. doi: 10.11622/smedj.2016142. Epub 2016 Aug 12.


A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence.

Chia JY, Tan WS, Ng CL, Hu NJ, Foo HL, Ho KL.

Sci Rep. 2016 Aug 9;6:31210. doi: 10.1038/srep31210.


CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs.

Ng CL, Siciliano G, Lee MC, de Almeida MJ, Corey VC, Bopp SE, Bertuccini L, Wittlin S, Kasdin RG, Le Bihan A, Clozel M, Winzeler EA, Alano P, Fidock DA.

Mol Microbiol. 2016 Aug;101(3):381-93. doi: 10.1111/mmi.13397. Epub 2016 May 7.


Characterization of a type I pullulanase from Anoxybacillus sp. SK3-4 reveals an unusual substrate hydrolysis.

Kahar UM, Ng CL, Chan KG, Goh KM.

Appl Microbiol Biotechnol. 2016 Jul;100(14):6291-307. doi: 10.1007/s00253-016-7451-6. Epub 2016 Mar 22.


Crystal structure of Anoxybacillus α-amylase provides insights into maltose binding of a new glycosyl hydrolase subclass.

Chai KP, Othman NF, Teh AH, Ho KL, Chan KG, Shamsir MS, Goh KM, Ng CL.

Sci Rep. 2016 Mar 15;6:23126. doi: 10.1038/srep23126.


Results of the treatment of keratocystic odontogenic tumours using enucleation and treatment of the residual bony defect with Carnoy's solution.

Leung YY, Lau SL, Tsoi KY, Ma HL, Ng CL.

Int J Oral Maxillofac Surg. 2016 Sep;45(9):1154-8. doi: 10.1016/j.ijom.2016.02.002. Epub 2016 Feb 26.


Cloning, expression, purification, crystallization and X-ray crystallographic analysis of recombinant human C1ORF123 protein.

Rahaman SN, Mat Yusop J, Mohamed-Hussein ZA, Ho KL, Teh AH, Waterman J, Ng CL.

Acta Crystallogr F Struct Biol Commun. 2016 Mar;72(Pt 3):207-13. doi: 10.1107/S2053230X16002016. Epub 2016 Feb 16.


Cloning, expression, purification, characterization, crystallization and X-ray crystallographic analysis of recombinant Der f 21 (rDer f 21) from Dermatophagoides farinae.

Pang SL, Ho KL, Waterman J, Teh AH, Chew FT, Ng CL.

Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1396-400. doi: 10.1107/S2053230X1501818X. Epub 2015 Oct 23.


Latest developments in allergic rhinitis in Allergy for clinicians and researchers.

Ng CL, Wang DY.

Allergy. 2015 Dec;70(12):1521-30. doi: 10.1111/all.12782. Review.


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